Publications Authored by IOA Division Leaders

• The role of Medicaid home- and community-based services in use of Medicare post-acute care.
  Health services research. 2024 Oct;59(5):e14325 Epub 2024 May 28; Authors: Wang S, Werner RM, Coe NB, Chua R, Qi M, Konetzka RT

• Association of quantitative histopathology measurements with antemortem medial temporal lobe cortical thickness in the Alzheimer's disease continuum.
  Acta neuropathologica. 2024 Sep 3;148(1):37; Authors: Denning AE, Ittyerah R, Levorse LM, Sadeghpour N, Athalye C, Chung E, Ravikumar S, Dong M, Duong MT, Li Y, Ilesanmi A, Sreepada LP, Sabatini P, Lowe M, Bahena A, Zablah J, Spencer BE, Watanabe R, Kim B, Sørensen MH, Khandelwal P, Brown C, Hrybouski S, Xie SX, de Flores R, Robinson JL, Schuck T, Ohm DT, Arezoumandan S, Porta S, Detre JA, Insausti R, Wisse LEM, Das SR, Irwin DJ, Lee EB, Wolk DA, Yushkevich PA

• The ADNI4 Digital Study: A novel approach to recruitment, screening, and assessment of participants for AD clinical research.
  Alzheimer's & dementia : the journal of the Alzheimer's Association. 2024 Sep 1; Authors: Miller MJ, Diaz A, Conti C, Albala B, Flenniken D, Fockler J, Kwang W, Sacrey DT, Ashford MT, Skirrow C, Weston J, Fristed E, Farias ST, Korecka M, Wan Y, Aisen PS, Beckett L, Harvey D, Lee EB, Petersen RC, Shaw LM, Okonkwo OC, Mindt MR, Weiner MW, Nosheny RL, Alzheimer's Disease Neuroimaging Initiative

• Ischemic stroke associated with amyloid-related imaging abnormalities in a patient treated with lecanemab.
  Alzheimer's & dementia : the journal of the Alzheimer's Association. 2024 Aug 30; Authors: Gibson AW, Elser H, Rosso M, Cornblath EJ, Fonkeu Y, Prasad S, Rothstein A, Nasrallah IM, Wolk DA, Guo MH

• Bridging the gap: Multi-omics profiling of brain tissue in Alzheimer's disease and older controls in multi-ethnic populations.
  Alzheimer's & dementia : the journal of the Alzheimer's Association. 2024 Aug 30; Authors: Reddy JS, Heath L, Linden AV, Allen M, Lopes KP, Seifar F, Wang E, Ma Y, Poehlman WL, Quicksall ZS, Runnels A, Wang Y, Duong DM, Yin L, Xu K, Modeste ES, Shantaraman A, Dammer EB, Ping L, Oatman SR, Scanlan J, Ho C, Carrasquillo MM, Atik M, Yepez G, Mitchell AO, Nguyen TT, Chen X, Marquez DX, Reddy H, Xiao H, Seshadri S, Mayeux R, Prokop S, Lee EB, Serrano GE, Beach TG, Teich AF, Haroutunian V, Fox EJ, Gearing M, Wingo A, Wingo T, Lah JJ, Levey AI, Dickson DW, Barnes LL, De Jager P, Zhang B, Bennett D, Seyfried NT, Greenwood AK, Ertekin-Taner N

• Alzheimer's Disease Seeded Tau Forms Paired Helical Filaments Yet Lacks Seeding Potential.
  The Journal of biological chemistry. 2024 Aug 28;:107730; Authors: Duan P, Dregni AJ, Xu H, Changolkar L, Lee VM, Lee EB, Hong M

• Epigenetic and genetic risk of Alzheimer disease from autopsied brains in two ethnic groups.
  Acta neuropathologica. 2024 Aug 23;148(1):27; Authors: Ma Y, Reyes-Dumeyer D, Piriz A, Recio P, Mejia DR, Medrano M, Lantigua RA, Vonsattel JPG, Tosto G, Teich AF, Ciener B, Leskinen S, Sivakumar S, DeTure M, Ranjan D, Dickson D, Murray M, Lee E, Wolk DA, Jin LW, Dugger BN, Hiniker A, Rissman RA, Mayeux R, Vardarajan BN

• Whole-genome sequencing analysis reveals new susceptibility loci and structural variants associated with progressive supranuclear palsy.
  Molecular neurodegeneration. 2024 Aug 16;19(1):61; Authors: Wang H, Chang TS, Dombroski BA, Cheng PL, Patil V, Valiente-Banuet L, Farrell K, Mclean C, Molina-Porcel L, Rajput A, De Deyn PP, Le Bastard N, Gearing M, Kaat LD, Van Swieten JC, Dopper E, Ghetti BF, Newell KL, Troakes C, de Yébenes JG, Rábano-Gutierrez A, Meller T, Oertel WH, Respondek G, Stamelou M, Arzberger T, Roeber S, Müller U, Hopfner F, Pastor P, Brice A, Durr A, Le Ber I, Beach TG, Serrano GE, Hazrati LN, Litvan I, Rademakers R, Ross OA, Galasko D, Boxer AL, Miller BL, Seeley WW, Van Deerlin VM, Lee EB, White CL 3rd, Morris H, de Silva R, Crary JF, Goate AM, Friedman JS, Leung YY, Coppola G, Naj AC, Wang LS, P. S. P. genetics study group, Dalgard C, Dickson DW, Höglinger GU, Schellenberg GD, Geschwind DH, Lee WP

• Brain aging patterns in a large and diverse cohort of 49,482 individuals.
  Nature medicine. 2024 Aug 15; Authors: Yang Z, Wen J, Erus G, Govindarajan ST, Melhem R, Mamourian E, Cui Y, Srinivasan D, Abdulkadir A, Parmpi P, Wittfeld K, Grabe HJ, Bülow R, Frenzel S, Tosun D, Bilgel M, An Y, Yi D, Marcus DS, LaMontagne P, Benzinger TLS, Heckbert SR, Austin TR, Waldstein SR, Evans MK, Zonderman AB, Launer LJ, Sotiras A, Espeland MA, Masters CL, Maruff P, Fripp J, Toga AW, O'Bryant S, Chakravarty MM, Villeneuve S, Johnson SC, Morris JC, Albert MS, Yaffe K, Völzke H, Ferrucci L, Nick Bryan R, Shinohara RT, Fan Y, Habes M, Lalousis PA, Koutsouleris N, Wolk DA, Resnick SM, Shou H, Nasrallah IM, Davatzikos C

• Cytoarchitectonic gradients of laminar degeneration in behavioural variant frontotemporal dementia.
  Brain : a journal of neurology. 2024 Aug 9; Authors: Ohm DT, Xie SX, Capp N, Arezoumandan S, Cousins KAQ, Rascovsky K, Wolk DA, Van Deerlin VM, Lee EB, McMillan CT, Irwin DJ

• Network proteomics of the Lewy body dementia brain reveals presynaptic signatures distinct from Alzheimer's disease.
  Molecular neurodegeneration. 2024 Aug 6;19(1):60; Authors: Shantaraman A, Dammer EB, Ugochukwu O, Duong DM, Yin L, Carter EK, Gearing M, Chen-Plotkin A, Lee EB, Trojanowski JQ, Bennett DA, Lah JJ, Levey AI, Seyfried NT, Higginbotham L

• Modernizing the Data Infrastructure for Clinical Research to Meet Evolving Demands for Evidence.
  JAMA. 2024 Aug 5; Authors: Franklin JB, Marra C, Abebe KZ, Butte AJ, Cook DJ, Esserman L, Fleisher LA, Grossman CI, Kass NE, Krumholz HM, Rowan K, Abernethy AP, JAMA Summit on Clinical Trials Participants

• A cross-sectional study of α-synuclein seed amplification assay in Alzheimer's disease neuroimaging initiative: Prevalence and associations with Alzheimer's disease biomarkers and cognitive function.
  Alzheimer's & dementia : the journal of the Alzheimer's Association. 2024 Aug;20(8):5114-5131 Epub 2024 May 21; Authors: Tosun D, Hausle Z, Iwaki H, Thropp P, Lamoureux J, Lee EB, MacLeod K, McEvoy S, Nalls M, Perrin RJ, Saykin AJ, Shaw LM, Singleton AB, Lebovitz R, Weiner MW, Blauwendraat C, Alzheimer's Disease Neuroimaging Initiative

• Comparison of the Amyloid Plaque Proteome in Down Syndrome, Early-Onset Alzheimer's Disease and Late-Onset Alzheimer's Disease.
  Research square. 2024 Jul 15; Authors: Martá-Ariza M, Leitner DF, Kanshin E, Suazo J, Pedrosa AG, Thierry M, Lee EB, Devinsky O, Drummond E, Fortea J, Lleó A, Ueberheide B, Wisniewski T

• Medicare expenditures among spouses of persons with dementia.
  Journal of the American Geriatrics Society. 2024 Jul 8; Authors: Ingraham BC, Barthold D, Coe NB, Fishman P

• Baseline levels and longitudinal changes in plasma Aβ42/40 among Black and white individuals.
  Nature communications. 2024 Jul 2;15(1):5539; Authors: Xiong C, Luo J, Wolk DA, Shaw LM, Roberson ED, Murchison CF, Henson RL, Benzinger TLS, Bui Q, Agboola F, Grant E, Gremminger EN, Moulder KL, Geldmacher DS, Clay OJ, Babulal G, Cruchaga C, Holtzman DM, Bateman RJ, Morris JC, Schindler SE

• Beyond Macrostructure: Is There a Role for Radiomics Analysis in Neuroimaging ?
  Magnetic resonance in medical sciences : MRMS : an official journal of Japan Society of Magnetic Resonance in Medicine. 2024 Jul 1;23(3):367-376 Epub 2024 Jun 14; Authors: Das SR, Ilesanmi A, Wolk DA, Gee JC

• Personalized and muscle-specific OXPHOS measurement with integrated CrCEST MRI and proton MR spectroscopy.
  Nature communications. 2024 Jun 25;15(1):5387; Authors: Armbruster RR, Kumar D, Benyard B, Jacobs P, Khandavilli A, Liu F, Nanga RPR, McCormack S, Cappola AR, Wilson N, Reddy R

• Annexin A11 aggregation in FTLD-TDP type C and related neurodegenerative disease proteinopathies.
  Acta neuropathologica. 2024 Jun 19;147(1):104; Authors: Robinson JL, Suh E, Xu Y, Hurtig HI, Elman L, McMillan CT, Irwin DJ, Porta S, Van Deerlin VM, Lee EB

• Double malnutrition and associated factors in a middle-aged and older, rural South African population.
  BMC nutrition. 2024 Jun 10;10(1):84; Authors: Seedat F, Tollman SM, Twine W, Cappola AR, Wade AN

• Impact of Magnetic Resonance Imaging Markers on the Diagnostic Performance of the International Parkinson and Movement Disorder Society Multiple System Atrophy Criteria.
  Movement disorders : official journal of the Movement Disorder Society. 2024 Jun 7; Authors: Jensen I, Heine J, Ruf VC, Compta Y, Porcel LM, Troakes C, Vamanu A, Downes S, Irwin D, Cohen J, Lee EB, Nilsson C, Englund E, Nemati M, Katzdobler S, Levin J, Pantelyat A, Seemiller J, Berger S, van Swieten J, Dopper E, Rozenmuller A, Kovacs GG, Bendahan N, Lang AE, Herms J, Höglinger G, Hopfner F

• Postmortem imaging reveals patterns of medial temporal lobe vulnerability to tau pathology in Alzheimer's disease.
  Nature communications. 2024 Jun 5;15(1):4803; Authors: Ravikumar S, Denning AE, Lim S, Chung E, Sadeghpour N, Ittyerah R, Wisse LEM, Das SR, Xie L, Robinson JL, Schuck T, Lee EB, Detre JA, Tisdall MD, Prabhakaran K, Mizsei G, de Onzono Martin MMI, Arroyo Jiménez MDM, Mũnoz M, Marcos Rabal MDP, Cebada Sánchez S, Delgado González JC, de la Rosa Prieto C, Irwin DJ, Wolk DA, Insausti R, Yushkevich PA

• Proteomic changes in the human cerebrovasculature in Alzheimer's disease and related tauopathies linked to peripheral biomarkers in plasma and cerebrospinal fluid.
  Alzheimer's & dementia : the journal of the Alzheimer's Association. 2024 Jun;20(6):4043-4065 Epub 2024 May 7; Authors: Wojtas AM, Dammer EB, Guo Q, Ping L, Shantaraman A, Duong DM, Yin L, Fox EJ, Seifar F, Lee EB, Johnson ECB, Lah JJ, Levey AI, Levites Y, Rangaraju S, Golde TE, Seyfried NT

• Pathologic and cognitive correlates of plasma biomarkers in neurodegenerative disease.
  Alzheimer's & dementia : the journal of the Alzheimer's Association. 2024 Jun;20(6):3889-3905 Epub 2024 Apr 21; Authors: Cousins KAQ, Phillips JS, Das SR, O'Brien K, Tropea TF, Chen-Plotkin A, Shaw LM, Nasrallah IM, Mechanic-Hamilton D, McMillan CT, Irwin DJ, Lee EB, Wolk DA

• Youth Caregivers of Adults in the United States: Prevalence and the Association Between Caregiving and Education.
  Demography. 2024 Jun 1;61(3):829-847; Authors: Miller KEM, Hart JL, Useche Rosania M, Coe NB

• Automatic segmentation of medial temporal lobe subregions in multi-scanner, multi-modality MRI of variable quality.
  bioRxiv : the preprint server for biology. 2024 May 23; Authors: Li Y, Xie L, Khandelwal P, Wisse LEM, Brown CA, Prabhakaran K, Dylan Tisdall M, Mechanic-Hamilton D, Detre JA, Das SR, Wolk DA, Yushkevich PA

• Improving Medical Communication-Reply.
  JAMA. 2024 May 14;331(18):1593; Authors: Cappola AR, Cohen KS

• Human iPSC 4R tauopathy model uncovers modifiers of tau propagation.
  Cell. 2024 May 9;187(10):2446-2464.e22 Epub 2024 Apr 5; Authors: Parra Bravo C, Giani AM, Madero-Perez J, Zhao Z, Wan Y, Samelson AJ, Wong MY, Evangelisti A, Cordes E, Fan L, Ye P, Zhu D, Pozner T, Mercedes M, Patel T, Yarahmady A, Carling GK, Sterky FH, Lee VMY, Lee EB, DeTure M, Dickson DW, Sharma M, Mok SA, Luo W, Zhao M, Kampmann M, Gong S, Gan L

• Comparison of histological delineations of medial temporal lobe cortices by four independent neuroanatomy laboratories.
  Hippocampus. 2024 May;34(5):241-260 Epub 2024 Feb 28; Authors: Wuestefeld A, Baumeister H, Adams JN, de Flores R, Hodgetts CJ, Mazloum-Farzaghi N, Olsen RK, Puliyadi V, Tran TT, Bakker A, Canada KL, Dalton MA, Daugherty AM, La Joie R, Wang L, Bedard ML, Buendia E, Chung E, Denning A, Del Mar Arroyo-Jiménez M, Artacho-Pérula E, Irwin DJ, Ittyerah R, Lee EB, Lim S, Del Pilar Marcos-Rabal M, Iñiguez de Onzoño Martin MM, Lopez MM, de la Rosa Prieto C, Schuck T, Trotman W, Vela A, Yushkevich P, Amunts K, Augustinack JC, Ding SL, Insausti R, Kedo O, Berron D, Wisse LEM

• MAPT H2 haplotype and risk of Pick's disease in the Pick's disease International Consortium: a genetic association study.
  The Lancet. Neurology. 2024 May;23(5):487-499; Authors: Valentino RR, Scotton WJ, Roemer SF, Lashley T, Heckman MG, Shoai M, Martinez-Carrasco A, Tamvaka N, Walton RL, Baker MC, Macpherson HL, Real R, Soto-Beasley AI, Mok K, Revesz T, Christopher EA, DeTure M, Seeley WW, Lee EB, Frosch MP, Molina-Porcel L, Gefen T, Redding-Ochoa J, Ghetti B, Robinson AC, Kobylecki C, Rowe JB, Beach TG, Teich AF, Keith JL, Bodi I, Halliday GM, Gearing M, Arzberger T, Morris CM, White CL 3rd, Mechawar N, Boluda S, MacKenzie IR, McLean C, Cykowski MD, Wang SJ, Graff C, Nagra RM, Kovacs GG, Giaccone G, Neumann M, Ang LC, Carvalho A, Morris HR, Rademakers R, Hardy JA, Dickson DW, Rohrer JD, Ross OA, Pick's disease International Consortium

• Large-scale Deep Proteomic Analysis in Alzheimer's Disease Brain Regions Across Race and Ethnicity.
  bioRxiv : the preprint server for biology. 2024 Apr 26; Authors: Seifar F, Fox EJ, Shantaraman A, Liu Y, Dammer EB, Modeste E, Duong DM, Yin L, Trautwig AN, Guo Q, Xu K, Ping L, Reddy JS, Allen M, Quicksall Z, Heath L, Scanlan J, Wang E, Wang M, Linden AV, Poehlman W, Chen X, Baheti S, Ho C, Nguyen T, Yepez G, Mitchell AO, Oatman SR, Wang X, Carrasquillo MM, Runnels A, Beach T, Serrano GE, Dickson DW, Lee EB, Golde TE, Prokop S, Barnes LL, Zhang B, Haroutunian V, Gearing M, Lah JJ, Jager P, Bennett DA, Greenwood A, Ertekin-Taner N, Levey AI, Wingo A, Wingo T, Seyfried NT

• Bridging the Gap: Multi-Omics Profiling of Brain Tissue in Alzheimer's Disease and Older Controls in Multi-Ethnic Populations.
  bioRxiv : the preprint server for biology. 2024 Apr 20; Authors: Reddy JS, Heath L, Vander Linden A, Allen M, de Paiva Lopes K, Seifar F, Wang E, Ma Y, Poehlman WL, Quicksall ZS, Runnels A, Wang Y, Duong DM, Yin L, Xu K, Modeste ES, Shantaraman A, Dammer EB, Ping L, Oatman SR, Scanlan J, Ho C, Carrasquillo MM, Atik M, Yepez G, Mitchell AO, Nguyen TT, Chen X, Marquez DX, Reddy H, Xiao H, Seshadri S, Mayeux R, Prokop S, Lee EB, Serrano GE, Beach TG, Teich AF, Haroutunian V, Fox EJ, Gearing M, Wingo A, Wingo T, Lah JJ, Levey AI, Dickson DW, Barnes LL, De Jager P, Zhang B, Bennett D, Seyfried NT, Greenwood AK, Ertekin-Taner N

• Default mode network tau predicts future clinical decline in atypical early Alzheimer's disease.
  medRxiv : the preprint server for health sciences. 2024 Apr 19; Authors: Katsumi Y, Howe IA, Eckbo R, Wong B, Quimby M, Hochberg D, McGinnis SM, Putcha D, Wolk DA, Touroutoglou A, Dickerson BC

• Money may matter: Financial hardship and its association with satisfaction of care among people living with dementia.
  Journal of the American Geriatrics Society. 2024 Apr;72(4):1272-1274 Epub 2023 Dec 29; Authors: Miller KEM, White L, Coe NB, Khandelwal N

• Neighborhood disadvantage reduces cognitive reserve independent of neuropathologic change.
  Alzheimer's & dementia : the journal of the Alzheimer's Association. 2024 Apr;20(4):2707-2718 Epub 2024 Feb 23; Authors: Kim B, Yannatos I, Blam K, Wiebe D, Xie SX, McMillan CT, Mechanic-Hamilton D, Wolk DA, Lee EB

• Misinformation and the Vaccine Adverse Event Reporting System.
  JAMA. 2024 Mar 26;331(12):1005-1006; Authors: Jamieson KH, Johnson KB, Cappola AR

• Ultrastructure of human brain tissue vitrified from autopsy revealed by cryo-ET with cryo-plasma FIB milling.
  Nature communications. 2024 Mar 26;15(1):2660; Authors: Creekmore BC, Kixmoeller K, Black BE, Lee EB, Chang YW

• Greater white matter degeneration and lower structural connectivity in non-amnestic vs. amnestic Alzheimer's disease.
  Frontiers in neuroscience. 2024;18:1353306 Epub 2024 Mar 18; Authors: Phillips JS, Adluru N, Chung MK, Radhakrishnan H, Olm CA, Cook PA, Gee JC, Cousins KAQ, Arezoumandan S, Wolk DA, McMillan CT, Grossman M, Irwin DJ

• MSUT2 regulates tau spreading via adenosinergic signaling mediated ASAP1 pathway in neurons.
  Acta neuropathologica. 2024 Mar 12;147(1):55; Authors: Xu H, Qiu Q, Hu P, Hoxha K, Jang E, O'Reilly M, Kim C, He Z, Marotta N, Changolkar L, Zhang B, Wu H, Schellenberg GD, Kraemer B, Luk KC, Lee EB, Trojanowski JQ, Brunden KR, Lee VM

• Deep sequencing of proteotoxicity modifier genes uncovers a Presenilin-2/beta-amyloid-actin genetic risk module shared among alpha-synucleinopathies.
  bioRxiv : the preprint server for biology. 2024 Mar 7; Authors: Nazeen S, Wang X, Zielinski D, Lam I, Hallacli E, Xu P, Ethier E, Strom R, Zanella CA, Nithianandam V, Ritter D, Henderson A, Saurat N, Afroz J, Nutter-Upham A, Benyamini H, Copty J, Ravishankar S, Morrow A, Mitchel J, Neavin D, Gupta R, Farbehi N, Grundman J, Myers RH, Scherzer CR, Trojanowski JQ, Van Deerlin VM, Cooper AA, Lee EB, Erlich Y, Lindquist S, Peng J, Geschwind DH, Powell J, Studer L, Feany MB, Sunyaev SR, Khurana V

• Tau maturation in the clinicopathological spectrum of Lewy body and Alzheimer's disease.
  Annals of clinical and translational neurology. 2024 Mar;11(3):673-685 Epub 2024 Jan 23; Authors: Arezoumandan S, Cousins KAQ, Ohm DT, Lowe M, Chen M, Gee J, Phillips JS, McMillan CT, Luk KC, Deik A, Spindler MA, Tropea TF, Weintraub D, Wolk DA, Grossman M, Lee V, Chen-Plotkin AS, Lee EB, Irwin DJ

• Impact of white matter hyperintensities on structural connectivity and cognition in cognitively intact ADNI participants.
  Neurobiology of aging. 2024 Mar;135:79-90 Epub 2023 Dec 12; Authors: Taghvaei M, Mechanic-Hamilton DJ, Sadaghiani S, Shakibajahromi B, Dolui S, Das S, Brown C, Tackett W, Khandelwal P, Cook P, Shinohara RT, Yushkevich P, Bassett DS, Wolk DA, Detre JA, Alzheimer’s Disease Neuroimaging Initiative

• Changing places: Longitudinal trends in living arrangements of persons living with dementia.
  Journal of the American Geriatrics Society. 2024 Mar;72(3):928-930 Epub 2023 Dec 5; Authors: White LLY, Sun C, Coe NB

• Tau-neurodegeneration mismatch reveals vulnerability and resilience to comorbidities in Alzheimer's continuum.
  Alzheimer's & dementia : the journal of the Alzheimer's Association. 2024 Mar;20(3):1586-1600 Epub 2023 Dec 5; Authors: Lyu X, Duong MT, Xie L, de Flores R, Richardson H, Hwang G, Wisse LEM, DiCalogero M, McMillan CT, Robinson JL, Xie SX, Lee EB, Irwin DJ, Dickerson BC, Davatzikos C, Nasrallah IM, Yushkevich PA, Wolk DA, Das SR, Alzheimer's Disease Neuroimaging Initiative

• Association of Structural Forms of 17q21.31 with the Risk of Progressive Supranuclear Palsy and MAPT Sub-haplotypes.
  medRxiv : the preprint server for health sciences. 2024 Feb 28; Authors: Wang H, Chang TS, Dombroski BA, Cheng PL, Si YQ, Tucci A, Patil V, Valiente-Banuet L, Farrell K, Mclean C, Molina-Porcel L, Alex R, Paul De Deyn P, Le Bastard N, Gearing M, Donker Kaat L, Van Swieten JC, Dopper E, Ghetti BF, Newell KL, Troakes C, G de Yébenes J, Rábano-Gutierrez A, Meller T, Oertel WH, Respondek G, Stamelou M, Arzberger T, Roeber S, Müller U, Hopfner F, Pastor P, Brice A, Durr A, Ber IL, Beach TG, Serrano GE, Hazrati LN, Litvan I, Rademakers R, Ross OA, Galasko D, Boxer AL, Miller BL, Seeley WW, Van Deerlin VM, Lee EB, White CL 3rd, Morris HR, de Silva R, Crary JF, Goate AM, Friedman JS, Leung YY, Coppola G, Naj AC, Wang LS, PSP genetics study group, Dickson DW, Höglinger GU, Tzeng JY, Geschwind DH, Schellenberg GD, Lee WP

• Automated Quality Evaluation Index for Arterial Spin Labeling Derived Cerebral Blood Flow Maps.
  Journal of magnetic resonance imaging : JMRI. 2024 Feb 24; Authors: Dolui S, Wang Z, Wolf RL, Nabavizadeh A, Xie L, Tosun D, Nasrallah IM, Wolk DA, Detre JA, Alzheimer's Disease Neuroimaging Initiative

• Does Consumer Credit Precede or Follow Health Among Older Adults? An Investigation in the Advanced Cognitive Training for Independent and Vital Elderly (ACTIVE) Trial.
  Innovation in aging. 2024;8(3):igae016 Epub 2024 Feb 22; Authors: Dean LT, Chung SE, Gross AL, Clay OJ, Willis SL, McDonough IM, Thomas KR, Marsiske M, Aysola J, Thorpe RJ Jr, Felix C, Berkowitz M, Coe NB

• Caregiving for dementia: trends pre-post onset and predictive factors of family caregiving (2002-2018).
  Health affairs scholar. 2024 Mar;2(3):qxae020 Epub 2024 Feb 16; Authors: Ingraham BC, Barthold D, Fishman P, Coe NB

• Polypathologic Associations with Gray Matter Atrophy in Neurodegenerative Disease.
  The Journal of neuroscience : the official journal of the Society for Neuroscience. 2024 Feb 7;44(6); Authors: Phillips JS, Robinson JL, Cousins KAQ, Wolk DA, Lee EB, McMillan CT, Trojanowski JQ, Grossman M, Irwin DJ

• Correlational analyses of biomarkers that are harmonized through a bridging study due to measurement errors.
  Statistical methods in medical research. 2024 Feb;33(2):185-202 Epub 2023 Nov 22; Authors: Xiong C, Schindler SE, Henson RL, Wolk DA, Shaw LM, Agboola F, Morris JC, Lu R, Luo J

• Demographic, clinical, biomarker, and neuropathological correlates of posterior cortical atrophy: an international cohort study and individual participant data meta-analysis.
  The Lancet. Neurology. 2024 Feb;23(2):168-177; Authors: Chapleau M, La Joie R, Yong K, Agosta F, Allen IE, Apostolova L, Best J, Boon BDC, Crutch S, Filippi M, Fumagalli GG, Galimberti D, Graff-Radford J, Grinberg LT, Irwin DJ, Josephs KA, Mendez MF, Mendez PC, Migliaccio R, Miller ZA, Montembeault M, Murray ME, Nemes S, Pelak V, Perani D, Phillips J, Pijnenburg Y, Rogalski E, Schott JM, Seeley W, Sullivan AC, Spina S, Tanner J, Walker J, Whitwell JL, Wolk DA, Ossenkoppele R, Rabinovici GD, PCA International Work Group

• Whole-Genome Sequencing Analysis Reveals New Susceptibility Loci and Structural Variants Associated with Progressive Supranuclear Palsy.
  medRxiv : the preprint server for health sciences. 2024 Jan 30; Authors: Wang H, Chang TS, Dombroski BA, Cheng PL, Patil V, Valiente-Banuet L, Farrell K, Mclean C, Molina-Porcel L, Rajput A, De Deyn PP, Bastard NL, Gearing M, Kaat LD, Swieten JCV, Dopper E, Ghetti BF, Newell KL, Troakes C, de Yébenes JG, Rábano-Gutierrez A, Meller T, Oertel WH, Respondek G, Stamelou M, Arzberger T, Roeber S, Müller U, Hopfner F, Pastor P, Brice A, Durr A, Ber IL, Beach TG, Serrano GE, Hazrati LN, Litvan I, Rademakers R, Ross OA, Galasko D, Boxer AL, Miller BL, Seeley WW, Deerlin VMV, Lee EB, White CL 3rd, Morris H, de Silva R, Crary JF, Goate AM, Friedman JS, Leung YY, Coppola G, Naj AC, Wang LS, PSP genetics study group, Dickson DW, Höglinger GU, Schellenberg GD, Geschwind DH, Lee WP

• Multi-trait analysis characterizes the genetics of thyroid function and identifies causal associations with clinical implications.
  Nature communications. 2024 Jan 30;15(1):888; Authors: Sterenborg RBTM, Steinbrenner I, Li Y, Bujnis MN, Naito T, Marouli E, Galesloot TE, Babajide O, Andreasen L, Astrup A, Åsvold BO, Bandinelli S, Beekman M, Beilby JP, Bork-Jensen J, Boutin T, Brody JA, Brown SJ, Brumpton B, Campbell PJ, Cappola AR, Ceresini G, Chaker L, Chasman DI, Concas MP, Coutinho de Almeida R, Cross SM, Cucca F, Deary IJ, Kjaergaard AD, Echouffo Tcheugui JB, Ellervik C, Eriksson JG, Ferrucci L, Freudenberg J, GHS DiscovEHR, Regeneron Genetics Center, Fuchsberger C, Gieger C, Giulianini F, Gögele M, Graham SE, Grarup N, Gunjača I, Hansen T, Harding BN, Harris SE, Haunsø S, Hayward C, Hui J, Ittermann T, Jukema JW, Kajantie E, Kanters JK, Kårhus LL, Kiemeney LALM, Kloppenburg M, Kühnel B, Lahti J, Langenberg C, Lapauw B, Leese G, Li S, Liewald DCM, Linneberg A, Lominchar JVT, Luan J, Martin NG, Matana A, Meima ME, Meitinger T, Meulenbelt I, Mitchell BD, Møllehave LT, Mora S, Naitza S, Nauck M, Netea-Maier RT, Noordam R, Nursyifa C, Okada Y, Onano S, Papadopoulou A, Palmer CNA, Pattaro C, Pedersen O, Peters A, Pietzner M, Polašek O, Pramstaller PP, Psaty BM, Punda A, Ray D, Redmond P, Richards JB, Ridker PM, Russ TC, Ryan KA, Olesen MS, Schultheiss UT, Selvin E, Siddiqui MK, Sidore C, Slagboom PE, Sørensen TIA, Soto-Pedre E, Spector TD, Spedicati B, Srinivasan S, Starr JM, Stott DJ, Tanaka T, Torlak V, Trompet S, Tuhkanen J, Uitterlinden AG, van den Akker EB, van den Eynde T, van der Klauw MM, van Heemst D, Verroken C, Visser WE, Vojinovic D, Völzke H, Waldenberger M, Walsh JP, Wareham NJ, Weiss S, Willer CJ, Wilson SG, Wolffenbuttel BHR, Wouters HJCM, Wright MJ, Yang Q, Zemunik T, Zhou W, Zhu G, Zöllner S, Smit JWA, Peeters RP, Köttgen A, Teumer A, Medici M

• Neurodegenerative Disease Tauopathies.
  Annual review of pathology. 2024 Jan 24;19:345-370 Epub 2023 Oct 13; Authors: Creekmore BC, Watanabe R, Lee EB

• Network Proteomics of the Lewy Body Dementia Brain Reveals Presynaptic Signatures Distinct from Alzheimer's Disease.
  bioRxiv : the preprint server for biology. 2024 Jan 24; Authors: Shantaraman A, Dammer EB, Ugochukwu O, Duong DM, Yin L, Carter EK, Gearing M, Chen-Plotkin A, Lee EB, Trojanowski JQ, Bennett DA, Lah JJ, Levey AI, Seyfried NT, Higginbotham L

• Correction: Baseline structural MRI and plasma biomarkers predict longitudinal structural atrophy and cognitive decline in early Alzheimer's disease.
  Alzheimer's research & therapy. 2024 Jan 12;16(1):11; Authors: Xie L, Das SR, Wisse LEM, Ittyerah R, de Flores R, Shaw LM, Yushkevich PA, Wolk DA, Alzheimer’s Disease Neuroimaging Initiative

• Proteomic Changes in the Human Cerebrovasculature in Alzheimer's Disease and Related Tauopathies Linked to Peripheral Biomarkers in Plasma and Cerebrospinal Fluid.
  medRxiv : the preprint server for health sciences. 2024 Jan 11; Authors: Wojtas AM, Dammer EB, Guo Q, Ping L, Shantaraman A, Duong DM, Yin L, Fox EJ, Seifar F, Lee EB, Johnson ECB, Lah JJ, Levey AI, Levites Y, Rangaraju S, Golde TE, Seyfried NT

• Gene-SGAN: discovering disease subtypes with imaging and genetic signatures via multi-view weakly-supervised deep clustering.
  Nature communications. 2024 Jan 8;15(1):354; Authors: Yang Z, Wen J, Abdulkadir A, Cui Y, Erus G, Mamourian E, Melhem R, Srinivasan D, Govindarajan ST, Chen J, Habes M, Masters CL, Maruff P, Fripp J, Ferrucci L, Albert MS, Johnson SC, Morris JC, LaMontagne P, Marcus DS, Benzinger TLS, Wolk DA, Shen L, Bao J, Resnick SM, Shou H, Nasrallah IM, Davatzikos C

• Comparison of histological delineations of medial temporal lobe cortices by four independent neuroanatomy laboratories.
  bioRxiv : the preprint server for biology. 2024 Jan 3; Authors: Wuestefeld A, Baumeister H, Adams JN, de Flores R, Hodgetts C, Mazloum-Farzaghi N, Olsen RK, Puliyadi V, Tran TT, Bakker A, Canada KL, Dalton MA, Daugherty AM, Joie R, Wang L, Bedard M, Buendia E, Chung E, Denning A, Arroyo-Jiménez MDM, Artacho-Pérula E, Irwin DJ, Ittyerah R, Lee EB, Lim S, Marcos-Rabal MDP, Martin MMIO, Lopez MM, Prieto CR, Schuck T, Trotman W, Vela A, Yushkevich P, Amunts K, Augustinack JC, Ding SL, Insausti R, Kedo O, Berron D, Wisse LEM

• Strategies to Improve Medical Communication.
  JAMA. 2024 Jan 2;331(1):70-71; Authors: Cappola AR, Cohen KS

• Inferring super-resolution tissue architecture by integrating spatial transcriptomics with histology.
  Nature biotechnology. 2024 Jan 2; Authors: Zhang D, Schroeder A, Yan H, Yang H, Hu J, Lee MYY, Cho KS, Susztak K, Xu GX, Feldman MD, Lee EB, Furth EE, Wang L, Li M

• WarpDrive: Improving spatial normalization using manual refinements.
  Medical image analysis. 2024 Jan;91:103041 Epub 2023 Nov 19; Authors: Oxenford S, Ríos AS, Hollunder B, Neudorfer C, Boutet A, Elias GJB, Germann J, Loh A, Deeb W, Salvato B, Almeida L, Foote KD, Amaral R, Rosenberg PB, Tang-Wai DF, Wolk DA, Burke AD, Sabbagh MN, Salloway S, Chakravarty MM, Smith GS, Lyketsos CG, Okun MS, Anderson WS, Mari Z, Ponce FA, Lozano A, Neumann WJ, Al-Fatly B, Horn A

• Five dominant dimensions of brain aging are identified via deep learning: associations with clinical, lifestyle, and genetic measures.
  medRxiv : the preprint server for health sciences. 2023 Dec 30; Authors: Yang Z, Wen J, Erus G, Govindarajan ST, Melhem R, Mamourian E, Cui Y, Srinivasan D, Abdulkadir A, Parmpi P, Wittfeld K, Grabe HJ, Bülow R, Frenzel S, Tosun D, Bilgel M, An Y, Yi D, Marcus DS, LaMontagne P, Benzinger TLS, Heckbert SR, Austin TR, Waldstein SR, Evans MK, Zonderman AB, Launer LJ, Sotiras A, Espeland MA, Masters CL, Maruff P, Fripp J, Toga A, O'Bryant S, Chakravarty MM, Villeneuve S, Johnson SC, Morris JC, Albert MS, Yaffe K, Völzke H, Ferrucci L, Bryan NR, Shinohara RT, Fan Y, Habes M, Lalousis PA, Koutsouleris N, Wolk DA, Resnick SM, Shou H, Nasrallah IM, Davatzikos C

• The neuropathology of intimate partner violence.
  Acta neuropathologica. 2023 Dec;146(6):803-815 Epub 2023 Oct 28; Authors: Dams-O'Connor K, Seifert AC, Crary JF, Delman BN, Del Bigio MR, Kovacs GG, Lee EB, Nolan AL, Pruyser A, Selmanovic E, Stewart W, Woodoff-Leith E, Folkerth RD

• Risk of chronic traumatic encephalopathy in rugby union is associated with length of playing career.
  Acta neuropathologica. 2023 Dec;146(6):829-832 Epub 2023 Oct 24; Authors: Stewart W, Buckland ME, Abdolmohammadi B, Affleck AJ, Alvarez VE, Gilchrist S, Huber BR, Lee EB, Lyall DM, Nowinski CJ, Russell ER, Stein TD, Suter CM, McKee AC

• APC and P53 mutations synergise to create a therapeutic vulnerability to NOTUM inhibition in advanced colorectal cancer.
  Gut. 2023 Nov 24;72(12):2294-2306; Authors: Tian Y, Wang X, Cramer Z, Rhoades J, Estep KN, Ma X, Adams-Tzivelekidis S, Katona BW, Johnson FB, Yu Z, Blanco MA, Lengner CJ, Li N

• Antiamyloid Monoclonal Antibody Therapy for Alzheimer Disease: Emerging Issues in Neurology.
  Neurology. 2023 Nov 7;101(19):842-852 Epub 2023 Jul 26; Authors: Ramanan VK, Armstrong MJ, Choudhury P, Coerver KA, Hamilton RH, Klein BC, Wolk DA, Wessels SR, Jones LK Jr, AAN Quality Committee

• Alzheimer Disease Biomarkers: Moving from CSF to Plasma for Reliable Detection of Amyloid and tau Pathology.
  Clinical chemistry. 2023 Nov 2;69(11):1247-1259; Authors: Kang JH, Korecka M, Lee EB, Cousins KAQ, Tropea TF, Chen-Plotkin AA, Irwin DJ, Wolk D, Brylska M, Wan Y, Shaw LM

• An autosomal-dominant childhood-onset disorder associated with pathogenic variants in VCP.
  American journal of human genetics. 2023 Nov 2;110(11):1959-1975 Epub 2023 Oct 25; Authors: Mah-Som AY, Daw J, Huynh D, Wu M, Creekmore BC, Burns W, Skinner SA, Holla ØL, Smeland MF, Planes M, Uguen K, Redon S, Bierhals T, Scholz T, Denecke J, Mensah MA, Sczakiel HL, Tichy H, Verheyen S, Blatterer J, Schreiner E, Thies J, Lam C, Spaeth CG, Pena L, Ramsey K, Narayanan V, Seaver LH, Rodriguez D, Afenjar A, Burglen L, Lee EB, Chou TF, Weihl CC, Shinawi MS

• Profiling baseline performance on the Longitudinal Early-Onset Alzheimer's Disease Study (LEADS) cohort near the midpoint of data collection.
  Alzheimer's & dementia : the journal of the Alzheimer's Association. 2023 Nov;19 Suppl 9(Suppl 9):S8-S18 Epub 2023 May 31; Authors: Hammers DB, Eloyan A, Taurone A, Thangarajah M, Beckett L, Gao S, Kirby K, Aisen P, Dage JL, Foroud T, Griffin P, Grinberg LT, Jack CR Jr, Kramer J, Koeppe R, Kukull WA, Mundada NS, La Joie R, Soleimani-Meigooni DN, Iaccarino L, Murray ME, Nudelman K, Polsinelli AJ, Rumbaugh M, Toga A, Touroutoglou A, Vemuri P, Atri A, Day GS, Duara R, Graff-Radford NR, Honig LS, Jones DT, Masdeu J, Mendez MF, Womack K, Musiek E, Onyike CU, Riddle M, Rogalski E, Salloway S, Sha SJ, Turner RS, Wingo TS, Wolk DA, Carrillo MC, Dickerson BC, Rabinovici GD, Apostolova LG, LEADS Consortium

• Baseline neuropsychiatric symptoms and psychotropic medication use midway through data collection of the Longitudinal Early-Onset Alzheimer's Disease Study (LEADS) cohort.
  Alzheimer's & dementia : the journal of the Alzheimer's Association. 2023 Nov;19 Suppl 9(Suppl 9):S42-S48 Epub 2023 Jun 9; Authors: Polsinelli AJ, Wonderlin RJ, Hammers DB, Garcia AP, Eloyan A, Taurone A, Thangarajah M, Beckett L, Gao S, Wang S, Kirby K, Logan PE, Aisen P, Dage JL, Foroud T, Griffin P, Iaccarino L, Kramer JH, Koeppe R, Kukull WA, La Joie R, Mundada NS, Murray ME, Nudelman K, Soleimani-Meigooni DN, Rumbaugh M, Toga AW, Touroutoglou A, Vemuri P, Atri A, Day GS, Duara R, Graff-Radford NR, Honig LS, Jones DT, Masdeu J, Mendez MF, Womack K, Musiek E, Onyike CU, Riddle M, Rogalski E, Salloway S, Sha SJ, Turner RS, Wingo TS, Wolk DA, Carrillo MC, Dickerson BC, Rabinovici GD, Apostolova LG, LEADS Consortium

• White matter hyperintensities are higher among early-onset Alzheimer's disease participants than their cognitively normal and early-onset nonAD peers: Longitudinal Early-onset Alzheimer's Disease Study (LEADS).
  Alzheimer's & dementia : the journal of the Alzheimer's Association. 2023 Nov;19 Suppl 9(Suppl 9):S89-S97 Epub 2023 Jul 25; Authors: Eloyan A, Thangarajah M, An N, Borowski BJ, Reddy AL, Aisen P, Dage JL, Foroud T, Ghetti B, Griffin P, Hammers D, Iaccarino L, Jack CR Jr, Kirby K, Kramer J, Koeppe R, Kukull WA, La Joie R, Mundada NS, Murray ME, Nudelman K, Rumbaugh M, Soleimani-Meigooni DN, Toga A, Touroutoglou A, Atri A, Day GS, Duara R, Graff-Radford NR, Honig LS, Jones DT, Masdeu J, Mendez MF, Musiek E, Onyike CU, Rogalski E, Salloway S, Sha S, Turner RS, Wingo TS, Wolk DA, Womack K, Beckett L, Gao S, Carrillo MC, Rabinovici G, Apostolova LG, Dickerson B, Vemuri P, LEADS Consortium

• Sex and APOE ε4 carrier effects on atrophy, amyloid PET, and tau PET burden in early-onset Alzheimer's disease.
  Alzheimer's & dementia : the journal of the Alzheimer's Association. 2023 Nov;19 Suppl 9(Suppl 9):S49-S63 Epub 2023 Jul 26; Authors: Nemes S, Logan PE, Manchella MK, Mundada NS, La Joie R, Polsinelli AJ, Hammers DB, Koeppe RA, Foroud TM, Nudelman KN, Eloyan A, Iaccarino L, Dorsant-Ardón V, Taurone A, Thangarajah M, Dage JL, Aisen P, Grinberg LT, Jack CR Jr, Kramer J, Kukull WA, Murray ME, Rumbaugh M, Soleimani-Meigooni DN, Toga A, Touroutoglou A, Vemuri P, Atri A, Day GS, Duara R, Graff-Radford NR, Honig LS, Jones DT, Masdeu J, Mendez MF, Musiek E, Onyike CU, Riddle M, Rogalski E, Salloway S, Sha SJ, Turner RS, Wingo TS, Womack KB, Wolk DA, Rabinovici GD, Carrillo MC, Dickerson BC, Apostolova LG, LEADS Consortium

• Detection of blood-brain barrier disruption in brains of patients with COVID-19, but no evidence of brain penetration by SARS-CoV-2.
  Acta neuropathologica. 2023 Nov;146(5):771-775 Epub 2023 Aug 25; Authors: Song H, Tomasevich A, Acheampong KK, Schaff DL, Shaffer SM, Dolle JP, Johnson VE, Mikytuck B, Lee EB, Nolan A, Keene CD, Weiss SR, Stewart W, Smith DH

• Influence of amyloid and diagnostic syndrome on non-traditional memory scores in early-onset Alzheimer's disease.
  Alzheimer's & dementia : the journal of the Alzheimer's Association. 2023 Nov;19 Suppl 9(Suppl 9):S29-S41 Epub 2023 Aug 31; Authors: Bushnell J, Hammers DB, Aisen P, Dage JL, Eloyan A, Foroud T, Grinberg LT, Iaccarino L, Jack CR Jr, Kirby K, Kramer J, Koeppe R, Kukull WA, La Joie R, Mundada NS, Murray ME, Nudelman K, Rumbaugh M, Soleimani-Meigooni DN, Toga A, Touroutoglou A, Vemuri P, Atri A, Day GS, Duara R, Graff-Radford NR, Honig LS, Jones DT, Masdeu J, Mendez M, Musiek E, Onyike CU, Riddle M, Rogalski E, Salloway S, Sha S, Turner RS, Wingo TS, Wolk DA, Carrillo MC, Dickerson BC, Rabinovici GD, Apostolova LG, Clark DG, LEADS Consortium

• Amyloid and tau-PET in early-onset AD: Baseline data from the Longitudinal Early-onset Alzheimer's Disease Study (LEADS).
  Alzheimer's & dementia : the journal of the Alzheimer's Association. 2023 Nov;19 Suppl 9(Suppl 9):S98-S114 Epub 2023 Sep 10; Authors: Cho H, Mundada NS, Apostolova LG, Carrillo MC, Shankar R, Amuiri AN, Zeltzer E, Windon CC, Soleimani-Meigooni DN, Tanner JA, Heath CL, Lesman-Segev OH, Aisen P, Eloyan A, Lee HS, Hammers DB, Kirby K, Dage JL, Fagan A, Foroud T, Grinberg LT, Jack CR, Kramer J, Kukull WA, Murray ME, Nudelman K, Toga A, Vemuri P, Atri A, Day GS, Duara R, Graff-Radford NR, Honig LS, Jones DT, Masdeu J, Mendez M, Musiek E, Onyike CU, Riddle M, Rogalski EJ, Salloway S, Sha S, Turner RS, Wingo TS, Wolk DA, Koeppe R, Iaccarino L, Dickerson BC, La Joie R, Rabinovici GD, LEADS Consortium

• Pathogenic variants in the Longitudinal Early-onset Alzheimer's Disease Study cohort.
  Alzheimer's & dementia : the journal of the Alzheimer's Association. 2023 Nov;19 Suppl 9(Suppl 9):S64-S73 Epub 2023 Oct 6; Authors: Nudelman KNH, Jackson T, Rumbaugh M, Eloyan A, Abreu M, Dage JL, Snoddy C, Faber KM, Foroud T, Hammers DB, DIAN/DIAN-TU Clinical/Genetics Committee, Taurone A, Thangarajah M, Aisen P, Beckett L, Kramer J, Koeppe R, Kukull WA, Murray ME, Toga AW, Vemuri P, Atri A, Day GS, Duara R, Graff-Radford NR, Honig LS, Jones DT, Masdeu JC, Mendez M, Musiek E, Onyike CU, Riddle M, Rogalski E, Salloway S, Sha SJ, Turner RS, Wingo TS, Wolk DA, Carrillo MC, Dickerson BC, Rabinovici GD, Apostolova LG, LEADS Consortium

• The Sporadic Early-onset Alzheimer's Disease Signature Of Atrophy: Preliminary Findings From The Longitudinal Early-onset Alzheimer's Disease Study (LEADS) Cohort.
  Alzheimer's & dementia : the journal of the Alzheimer's Association. 2023 Nov;19 Suppl 9(Suppl 9):S74-S88 Epub 2023 Oct 18; Authors: Touroutoglou A, Katsumi Y, Brickhouse M, Zaitsev A, Eckbo R, Aisen P, Beckett L, Dage JL, Eloyan A, Foroud T, Ghetti B, Griffin P, Hammers D, Jack CR Jr, Kramer JH, Iaccarino L, Joie R, Mundada NS, Koeppe R, Kukull WA, Murray ME, Nudelman K, Polsinelli AJ, Rumbaugh M, Soleimani-Meigooni DN, Toga A, Vemuri P, Atri A, Day GS, Duara R, Graff-Radford NR, Honig LS, Jones DT, Masdeu JC, Mendez MF, Musiek E, Onyike CU, Riddle M, Rogalski E, Salloway S, Sha S, Turner RS, Wingo TS, Wolk DA, Womack K, Carrillo MC, Rabinovici GD, Apostolova LG, Dickerson BC, LEADS Consortium

• Learning slopes in early-onset Alzheimer's disease.
  Alzheimer's & dementia : the journal of the Alzheimer's Association. 2023 Nov;19 Suppl 9(Suppl 9):S19-S28 Epub 2023 May 27; Authors: Hammers DB, Nemes S, Diedrich T, Eloyan A, Kirby K, Aisen P, Kramer J, Nudelman K, Foroud T, Rumbaugh M, Atri A, Day GS, Duara R, Graff-Radford NR, Honig LS, Jones DT, Masdeu JC, Mendez MF, Musiek E, Onyike CU, Riddle M, Rogalski E, Salloway S, Sha SJ, Turner RS, Weintraub S, Wingo TS, Wolk DA, Wong B, Carrillo MC, Dickerson BC, Rabinovici GD, Apostolova LG, LEADS Consortium

• Cerebrospinal fluid biomarkers in the Longitudinal Early-onset Alzheimer's Disease Study.
  Alzheimer's & dementia : the journal of the Alzheimer's Association. 2023 Nov;19 Suppl 9(Suppl 9):S115-S125 Epub 2023 Jul 25; Authors: Dage JL, Eloyan A, Thangarajah M, Hammers DB, Fagan AM, Gray JD, Schindler SE, Snoddy C, Nudelman KNH, Faber KM, Foroud T, Aisen P, Griffin P, Grinberg LT, Iaccarino L, Kirby K, Kramer J, Koeppe R, Kukull WA, La Joie R, Mundada NS, Murray ME, Rumbaugh M, Soleimani-Meigooni DN, Toga AW, Touroutoglou A, Vemuri P, Atri A, Beckett LA, Day GS, Graff-Radford NR, Duara R, Honig LS, Jones DT, Masdeu JC, Mendez MF, Musiek E, Onyike CU, Riddle M, Rogalski E, Salloway S, Sha SJ, Turner RS, Wingo TS, Wolk DA, Womack KB, Carrillo MC, Dickerson BC, Rabinovici GD, Apostolova LG, LEADS Consortium

• C9orf72 proline-arginine dipeptide repeats disrupt the proteasome and perturb proteolytic activities.
  Journal of neuropathology and experimental neurology. 2023 Oct 20;82(11):901-910; Authors: Zhang Y, Nelson SCK, Viera Ortiz AP, Lee EB, Fairman R

• Neuroanatomical and cellular degeneration associated with a social disorder characterized by new ritualistic belief systems in a TDP-C patient vs. a Pick patient.
  Frontiers in neurology. 2023;14:1245886 Epub 2023 Oct 11; Authors: Ohm DT, Rhodes E, Bahena A, Capp N, Lowe M, Sabatini P, Trotman W, Olm CA, Phillips J, Prabhakaran K, Rascovsky K, Massimo L, McMillan C, Gee J, Tisdall MD, Yushkevich PA, Lee EB, Grossman M, Irwin DJ

• Predictors of Adherence to Continuous Positive Airway Pressure in Older Adults With Apnea and Amnestic Mild Cognitive Impairment.
  The journals of gerontology. Series A, Biological sciences and medical sciences. 2023 Oct 9;78(10):1861-1870; Authors: Richards KC, Lozano AJ, Morris J, Moelter ST, Ji W, Vallabhaneni V, Wang Y, Chi L, Davis EM, Cheng C, Aguilar V, Khan S, Sankhavaram M, Hanlon AL, Wolk DA, Gooneratne N

• Correction: APOE and TREM2 regulate amyloid-responsive microglia in Alzheimer's disease.
  Acta neuropathologica. 2023 Oct;146(4):661; Authors: Nguyen AT, Wang K, Hu G, Wang X, Miao Z, Azevedo JA, Suh E, Van Deerlin VM, Choi D, Roeder K, Li M, Lee EB

• Effects of Cognitive Training on Alzheimer's Disease and Related Dementias: The Moderating Role of Social Determinants of Health.
  Journal of aging and health. 2023 Oct;35(9_suppl):40S-50S; Authors: Rebok GW, Gellert A, Coe NB, Clay OJ, Wallace G, Parisi JM, Aiken-Morgan AT, Crowe M, Ball K, Thorpe RJ Jr, Marsiske M, Zahodne LB, Felix C, Willis SL

• Does Consumer Credit Precede or Follow Changes in Cognitive Impairment Among Older Adults? An Investigation in the Advanced Cognitive Training for Independent and Vital Elderly (ACTIVE) Trial.
  Journal of aging and health. 2023 Oct;35(9_suppl):84S-94S; Authors: Dean LT, Chung SE, Gross AL, Clay OJ, Willis SL, Crowe M, McDonough IM, Thomas KR, Marsiske M, Aysola J, Thorpe RJ Jr, Felix C, Berkowitz M, Coe NB

• The optimal healthy ranges of thyroid function defined by the risk of cardiovascular disease and mortality: systematic review and individual participant data meta-analysis.
  The lancet. Diabetes & endocrinology. 2023 Oct;11(10):743-754 Epub 2023 Sep 8; Authors: Xu Y, Derakhshan A, Hysaj O, Wildisen L, Ittermann T, Pingitore A, Abolhassani N, Medici M, Kiemeney LALM, Riksen NP, Dullaart RPF, Trompet S, Dörr M, Brown SJ, Schmidt B, Führer-Sakel D, Vanderpump MPJ, Muendlein A, Drexel H, Fink HA, Ikram MK, Kavousi M, Rhee CM, Bensenor IM, Azizi F, Hankey GJ, Iacoviello M, Imaizumi M, Ceresini G, Ferrucci L, Sgarbi JA, Bauer DC, Wareham N, Boelaert K, Bakker SJL, Jukema JW, Vaes B, Iervasi G, Yeap BB, Westendorp RGJ, Korevaar TIM, Völzke H, Razvi S, Gussekloo J, Walsh JP, Cappola AR, Rodondi N, Peeters RP, Chaker L, Thyroid Studies Collaboration

• Telomeric DNA breaks in human induced pluripotent stem cells trigger ATR-mediated arrest and telomerase-independent telomere damage repair.
  Journal of molecular cell biology. 2023 Sep 28; Authors: Estep KN, Tobias JW, Fernandez RJ, Beveridge BM, Johnson FB

• Native ultrastructure of fresh human brain vitrified directly from autopsy revealed by cryo-electron tomography with cryo-plasma focused ion beam milling.
  bioRxiv : the preprint server for biology. 2023 Sep 17; Authors: Creekmore BC, Kixmoeller K, Black BE, Lee EB, Chang YW

• Aging and Alzheimer's disease have dissociable effects on local and regional medial temporal lobe connectivity.
  Brain communications. 2023;5(5):fcad245 Epub 2023 Sep 14; Authors: Hrybouski S, Das SR, Xie L, Wisse LEM, Kelley M, Lane J, Sherin M, DiCalogero M, Nasrallah I, Detre J, Yushkevich PA, Wolk DA

• Can a Home-Based Collaborative Care Model Reduce Health Services Utilization for Older Medicaid Beneficiaries Living with Depression and Co-occurring Chronic Conditions? A Quasi-experimental Study.
  Administration and policy in mental health. 2023 Sep;50(5):712-724 Epub 2023 May 26; Authors: Steinman L, Xing J, Court B, Coe NB, Yip A, Hill C, Rector B, Baquero B, Weiner BJ, Snowden M

• Rural disparities in use of family and formal caregiving for older adults with disabilities.
  Journal of the American Geriatrics Society. 2023 Sep;71(9):2865-2870 Epub 2023 Apr 20; Authors: Miller KEM, Ornstein KA, Coe NB

• Efficacy and Safety of Lenabasum, a Cannabinoid Type 2 Receptor Agonist, in a Phase 3 Randomized Trial in Diffuse Cutaneous Systemic Sclerosis.
  Arthritis & rheumatology (Hoboken, N.J.). 2023 Sep;75(9):1608-1618 Epub 2023 Jun 15; Authors: Spiera R, Kuwana M, Khanna D, Hummers L, Frech TM, Stevens W, Matucci-Cerinic M, Kafaja S, Distler O, Jun JB, Levy Y, Leszcyzński P, Gordon J, Steen V, Lee EB, Jankowski T, Litinsky I, Chung L, Hsu V, Mayes M, Sandorfi N, Simms RW, Finzel S, de Vries-Bouwstra J, Constantine S, Dgetluck N, Dinh Q, Bloom BJ, Furst DE, White B, Denton CP, RESOLVE-1 Study Group

• Gender of Study Partners and Research Participants Associated With Differences in Study Partner Ratings of Cognition and Activity Level.
  The journals of gerontology. Series B, Psychological sciences and social sciences. 2023 Aug 2;78(8):1318-1329; Authors: Stites SD, Gurian A, Coykendall C, Largent EA, Harkins K, Karlawish J, Coe NB

• Human Alzheimer's disease reactive astrocytes exhibit a loss of homeostastic gene expression.
  Acta neuropathologica communications. 2023 Aug 2;11(1):127; Authors: Dai DL, Li M, Lee EB

• When Alzheimer's is LATE: Why Does it Matter?
  Annals of neurology. 2023 Aug;94(2):211-222 Epub 2023 Jun 12; Authors: Nelson PT, Schneider JA, Jicha GA, Duong MT, Wolk DA

• Hormones and Aging: An Endocrine Society Scientific Statement.
  The Journal of clinical endocrinology and metabolism. 2023 Jul 14;108(8):1835-1874; Authors: Cappola AR, Auchus RJ, El-Hajj Fuleihan G, Handelsman DJ, Kalyani RR, McClung M, Stuenkel CA, Thorner MO, Verbalis JG

• Leveraging spatial transcriptomics data to recover cell locations in single-cell RNA-seq with CeLEry.
  Nature communications. 2023 Jul 8;14(1):4050; Authors: Zhang Q, Jiang S, Schroeder A, Hu J, Li K, Zhang B, Dai D, Lee EB, Xiao R, Li M

• Impaired ribosome-associated quality control of C9orf72 arginine-rich dipeptide-repeat proteins.
  Brain : a journal of neurology. 2023 Jul 3;146(7):2897-2912; Authors: Viera Ortiz AP, Cajka G, Olatunji OA, Mikytuck B, Shalem O, Lee EB

• Data-driven neuropathological staging and subtyping of TDP-43 proteinopathies.
  Brain : a journal of neurology. 2023 Jul 3;146(7):2975-2988; Authors: Young AL, Vogel JW, Robinson JL, McMillan CT, Ossenkoppele R, Wolk DA, Irwin DJ, Elman L, Grossman M, Lee VMY, Lee EB, Hansson O

• Young versus older subject diffusion magnetic resonance imaging data for virtual white matter lesion tractography.
  Human brain mapping. 2023 Jul;44(10):3943-3953 Epub 2023 May 6; Authors: Taghvaei M, Cook P, Sadaghiani S, Shakibajahromi B, Tackett W, Dolui S, De D, Brown C, Khandelwal P, Yushkevich P, Das S, Wolk DA, Detre JA

• Cellular processing of α-synuclein fibrils results in distinct physiological C-terminal truncations with a major cleavage site at residue Glu 114.
  The Journal of biological chemistry. 2023 Jul;299(7):104912 Epub 2023 Jun 10; Authors: Quintin S, Lloyd GM, Paterno G, Xia Y, Sorrentino Z, Bell BM, Gorion KM, Lee EB, Prokop S, Giasson BI

• Family spillovers and long-term care insurance.
  Journal of health economics. 2023 Jul;90:102781 Epub 2023 Jun 12; Authors: Coe NB, Goda GS, Van Houtven CH

• Apraxia of Speech in the Spontaneous Speech of Nonfluent/Agrammatic Primary Progressive Aphasia.
  Journal of Alzheimer's disease reports. 2023;7(1):589-604 Epub 2023 Jun 8; Authors: Ash S, Nevler N, Irwin DJ, Shellikeri S, Rascovsky K, Shaw L, Lee EB, Trojanowski JQ, Grossman M

• Associations of phosphorylated tau pathology with whole-hemisphere ex vivo morphometry in 7 tesla MRI.
  Alzheimer's & dementia : the journal of the Alzheimer's Association. 2023 Jun;19(6):2355-2364 Epub 2022 Dec 4; Authors: Sadaghiani S, Trotman W, Lim SA, Chung E, Ittyerah R, Ravikumar S, Khandelwal P, Prabhakaran K, Lavery ML, Ohm DT, Gabrielyan M, Das SR, Schuck T, Capp N, Peterson CS, Migdal E, Artacho-Pérula E, Jiménez MDMA, Rabal MDPM, Sánchez SC, Prieto CR, Parada MC, Insausti R, Robinson JL, McMillan C, Grossman M, Lee EB, Detre JA, Xie SX, Trojanowski JQ, Tisdall MD, Wisse LEM, Irwin DJ, Wolk DA, Yushkevich PA

• Pathological combinations in neurodegenerative disease are heterogeneous and disease-associated.
  Brain : a journal of neurology. 2023 Jun 1;146(6):2557-2569; Authors: Robinson JL, Xie SX, Baer DR, Suh E, Van Deerlin VM, Loh NJ, Irwin DJ, McMillan CT, Wolk DA, Chen-Plotkin A, Weintraub D, Schuck T, Lee VMY, Trojanowski JQ, Lee EB

• The perils of contact sport: pathologies of diffuse brain swelling and chronic traumatic encephalopathy neuropathologic change in a 23-year-old rugby union player.
  Acta neuropathologica. 2023 Jun;145(6):847-850 Epub 2023 Apr 22; Authors: Lee EB, Kennedy-Dietrich C, Geddes JF, Nicoll JAR, Revesz T, Smith DH, Stewart W

• Deciphering tumor ecosystems at super resolution from spatial transcriptomics with TESLA.
  Cell systems. 2023 May 17;14(5):404-417.e4 Epub 2023 May 9; Authors: Hu J, Coleman K, Zhang D, Lee EB, Kadara H, Wang L, Li M

• Antemortem network analysis of spreading pathology in autopsy-confirmed frontotemporal degeneration.
  Brain communications. 2023;5(3):fcad147 Epub 2023 May 12; Authors: Chen M, Burke S, Olm CA, Irwin DJ, Massimo L, Lee EB, Trojanowski JQ, Gee JC, Grossman M

• Retinal photoreceptor layer thickness has disease specificity and distinguishes predicted FTLD-Tau from biomarker-determined Alzheimer's disease.
  Neurobiology of aging. 2023 May;125:74-82 Epub 2023 Feb 1; Authors: Kim BJ, Grossman M, Aleman TS, Song D, Cousins KAQ, McMillan CT, Saludades A, Yu Y, Lee EB, Wolk D, Van Deerlin VM, Shaw LM, Ying GS, Irwin DJ

• Plasma GFAP associates with secondary Alzheimer's pathology in Lewy body disease.
  Annals of clinical and translational neurology. 2023 May;10(5):802-813 Epub 2023 Mar 31; Authors: Cousins KAQ, Irwin DJ, Chen-Plotkin A, Shaw LM, Arezoumandan S, Lee EB, Wolk DA, Weintraub D, Spindler M, Deik A, Grossman M, Tropea TF

• Concomitant Alzheimer Disease Pathology in Parkinson Disease Dementia.
  Annals of neurology. 2023 May;93(5):1045-1046 Epub 2023 Mar 16; Authors: Tropea TF, Albuja I, Cousins KAQ, Irwin DJ, Lee EB, Chen-Plotkin AS

• A Step Forward in the Fight Against Dementia-Are We There Yet?
  JAMA neurology. 2023 May 1;80(5):429-430; Authors: Wolk DA, Rabinovici GD, Dickerson BC

• Correction to: Isoform-specific patterns of tau burden and neuronal degeneration in MAPT-associated frontotemporal lobar degeneration.
  Acta neuropathologica. 2023 May;145(5):711; Authors: Giannini LAA, Ohm DT, Rozemuller AJM, Dratch L, Suh E, van Deerlin VM, Trojanowski JQ, Lee EB, van Swieten JC, Grossman M, Seelaar H, Irwin DJ, Netherlands Brain Bank

• Patient Experience at US Hospitals Following the Caregiver Advise, Record, Enable (CARE) Act.
  JAMA network open. 2023 May 1;6(5):e2311253; Authors: Lee CR, Taggert E, Coe NB, Chatterjee P

• Creating the Pick's disease International Consortium: Association study of MAPT H2 haplotype with risk of Pick's disease.
  medRxiv : the preprint server for health sciences. 2023 Apr 24; Authors: Valentino RR, Scotton WJ, Roemer SF, Lashley T, Heckman MG, Shoai M, Martinez-Carrasco A, Tamvaka N, Walton RL, Baker MC, Macpherson HL, Real R, Soto-Beasley AI, Mok K, Revesz T, Warner TT, Jaunmuktane Z, Boeve BF, Christopher EA, DeTure M, Duara R, Graff-Radford NR, Josephs KA, Knopman DS, Koga S, Murray ME, Lyons KE, Pahwa R, Parisi JE, Petersen RC, Whitwell J, Grinberg LT, Miller B, Schlereth A, Seeley WW, Spina S, Grossman M, Irwin DJ, Lee EB, Suh E, Trojanowski JQ, Van Deerlin VM, Wolk DA, Connors TR, Dooley PM, Frosch MP, Oakley DH, Aldecoa I, Balasa M, Gelpi E, Borrego-Écija S, de Eugenio Huélamo RM, Gascon-Bayarri J, Sánchez-Valle R, Sanz-Cartagena P, Piñol-Ripoll G, Molina-Porcel L, Bigio EH, Flanagan ME, Gefen T, Rogalski EJ, Weintraub S, Redding-Ochoa J, Chang K, Troncoso JC, Prokop S, Newell KL, Ghetti B, Jones M, Richardson A, Robinson AC, Roncaroli F, Snowden J, Allinson K, Green O, Rowe JB, Singh P, Beach TG, Serrano GE, Flowers XE, Goldman JE, Heaps AC, Leskinen SP, Teich AF, Black SE, Keith JL, Masellis M, Bodi I, King A, Sarraj SA, Troakes C, Halliday GM, Hodges JR, Kril JJ, Kwok JB, Piguet O, Gearing M, Arzberger T, Roeber S, Attems J, Morris CM, Thomas AJ, Evers BM, White CL, Mechawar N, Sieben AA, Cras PP, De Vil BB, De Deyn PPPP, Duyckaerts C, Le Ber I, Seihean D, Turbant-Leclere S, MacKenzie IR, McLean C, Cykowski MD, Ervin JF, Wang SJ, Graff C, Nennesmo I, Nagra RM, Riehl J, Kovacs GG, Giaccone G, Nacmias B, Neumann M, Ang LC, Finger EC, Blauwendraat C, Nalls MA, Singleton AB, Vitale D, Cunha C, Carvalho A, Wszolek ZK, Morris HR, Rademakers R, Hardy JA, Dickson DW, Rohrer JD, Ross OA

• Baseline structural MRI and plasma biomarkers predict longitudinal structural atrophy and cognitive decline in early Alzheimer's disease.
  Alzheimer's research & therapy. 2023 Apr 11;15(1):79; Authors: Xie L, Das SR, Wisse LEM, Ittyerah R, de Flores R, Shaw LM, Yushkevich PA, Wolk DA, Alzheimer’s Disease Neuroimaging Initiative

• Regional Deep Atrophy: a Self-Supervised Learning Method to Automatically Identify Regions Associated With Alzheimer's Disease Progression From Longitudinal MRI.
  ArXiv. 2023 Apr 10; Authors: Dong M, Xie L, Das SR, Wang J, Wisse LEM, deFlores R, Wolk DA, Yushkevich PA, Alzheimer’s Disease Neuroimaging Initiative

• SpaDecon: cell-type deconvolution in spatial transcriptomics with semi-supervised learning.
  Communications biology. 2023 Apr 7;6(1):378; Authors: Coleman K, Hu J, Schroeder A, Lee EB, Li M

• Racial and ethnic disparities in access to and enrollment in high-quality Medicare Advantage plans.
  Health services research. 2023 Apr;58(2):303-313 Epub 2022 Apr 9; Authors: Park S, Werner RM, Coe NB

• Multiscale functional connectivity patterns of the aging brain learned from harmonized rsfMRI data of the multi-cohort iSTAGING study.
  NeuroImage. 2023 Apr 1;269:119911 Epub 2023 Jan 30; Authors: Zhou Z, Li H, Srinivasan D, Abdulkadir A, Nasrallah IM, Wen J, Doshi J, Erus G, Mamourian E, Bryan NR, Wolk DA, Beason-Held L, Resnick SM, Satterthwaite TD, Davatzikos C, Shou H, Fan Y, ISTAGING Consortium

• Ex vivo, in situ perfusion protocol for human brain fixation compatible with microscopy, MRI techniques, and anatomical studies.
  Frontiers in neuroanatomy. 2023;17:1149674 Epub 2023 Mar 23; Authors: Insausti R, Insausti AM, Muñoz López M, Medina Lorenzo I, Arroyo-Jiménez MDM, Marcos Rabal MP, de la Rosa-Prieto C, Delgado-González JC, Montón Etxeberria J, Cebada-Sánchez S, Raspeño-García JF, Iñiguez de Onzoño MM, Molina Romero FJ, Benavides-Piccione R, Tapia-González S, Wisse LEM, Ravikumar S, Wolk DA, DeFelipe J, Yushkevich P, Artacho-Pérula E

• Novel VCP activator reverses multisystem proteinopathy nuclear proteostasis defects and enhances TDP-43 aggregate clearance.
  bioRxiv : the preprint server for biology. 2023 Mar 15; Authors: Phan JM, Creekmore BC, Nguyen AT, Bershadskaya DD, Darwich NF, Lee EB

• Paid Care Services and Transitioning out of the Community Among Black and White Older Adults With Dementia.
  The journals of gerontology. Series B, Psychological sciences and social sciences. 2023 Mar 13;78(Suppl 1):S91-S100; Authors: Roche-Dean M, Baik S, Moon H, Coe NB, Oh A, Zahodne LB

• Medicaid Integrated Purchasing for Physical and Behavioral Health: Early Adopters' Perceptions of Payment Reform Implementation in Washington State.
  Hospital topics. 2023 Mar 2;:1-13; Authors: Wood SJ, Conrad D, Grembowski D, Coe NB, Fishman P, Teutsch E

• Association of Intensive vs Standard Blood Pressure Control With Regional Changes in Cerebral Small Vessel Disease Biomarkers: Post Hoc Secondary Analysis of the SPRINT MIND Randomized Clinical Trial.
  JAMA network open. 2023 Mar 1;6(3):e231055; Authors: Rashid T, Li K, Toledo JB, Nasrallah I, Pajewski NM, Dolui S, Detre J, Wolk DA, Liu H, Heckbert SR, Bryan RN, Williamson J, Davatzikos C, Seshadri S, Launer LJ, Habes M

• Data-driven neuropathological staging and subtyping of TDP-43 proteinopathies.
  medRxiv : the preprint server for health sciences. 2023 Feb 2; Authors: Young AL, Vogel JW, Robinson JL, McMillan CT, Ossenkoppele R, Wolk DA, Irwin DJ, Elman L, Grossman M, Lee VM, Lee EB, Hansson O

• Growth of Private Pay Senior Housing Communities in Metropolitan Statistical Areas in the United States: 2015-2019.
  Medical care research and review : MCRR. 2023 Feb;80(1):101-108 Epub 2022 Jul 5; Authors: Miller KEM, Zhao J, Laine LT, Coe NB

• LATE-NC staging in routine neuropathologic diagnosis: an update.
  Acta neuropathologica. 2023 Feb;145(2):159-173 Epub 2022 Dec 13; Authors: Nelson PT, Lee EB, Cykowski MD, Alafuzoff I, Arfanakis K, Attems J, Brayne C, Corrada MM, Dugger BN, Flanagan ME, Ghetti B, Grinberg LT, Grossman M, Grothe MJ, Halliday GM, Hasegawa M, Hokkanen SRK, Hunter S, Jellinger K, Kawas CH, Keene CD, Kouri N, Kovacs GG, Leverenz JB, Latimer CS, Mackenzie IR, Mao Q, McAleese KE, Merrick R, Montine TJ, Murray ME, Myllykangas L, Nag S, Neltner JH, Newell KL, Rissman RA, Saito Y, Sajjadi SA, Schwetye KE, Teich AF, Thal DR, Tomé SO, Troncoso JC, Wang SJ, White CL 3rd, Wisniewski T, Yang HS, Schneider JA, Dickson DW, Neumann M

• Abundant copathologies of polyglucosan bodies, frontotemporal lobar degeneration with TDP-43 inclusions and ageing-related tau astrogliopathy in a family with a GBE1 mutation.
  Neuropathology and applied neurobiology. 2023 Feb;49(1):e12865; Authors: Uemura MT, Suh ER, Robinson JL, Brunden KR, Grossman M, Irwin DJ, Lee VM, Trojanowski JQ, Lee EB, Van Deerlin VM

• Association of CSF GAP-43 With the Rate of Cognitive Decline and Progression to Dementia in Amyloid-Positive Individuals.
  Neurology. 2023 Jan 17;100(3):e275-e285 Epub 2022 Oct 3; Authors: Öhrfelt A, Benedet AL, Ashton NJ, Kvartsberg H, Vandijck M, Weiner MW, Trojanowski JQ, Shaw LM, Zetterberg H, Blennow K, Alzheimer's Disease Neuroimaging Initiative

• Patient-Induced Pluripotent Stem Cell-Derived Hepatostellate Organoids Establish a Basis for Liver Pathologies in Telomeropathies.
  Cellular and molecular gastroenterology and hepatology. 2023;16(3):451-472 Epub 2023 Jun 9; Authors: Choi YJ, Kim MS, Rhoades JH, Johnson NM, Berry CT, Root S, Chen Q, Tian Y, Fernandez RJ 3rd, Cramer Z, Adams-Tzivelekidis S, Li N, Johnson FB, Lengner CJ

• Association of Medicare Advantage star ratings with patterns of end-of-life care.
  Journal of the American Geriatrics Society. 2023 Jan;71(1):279-282 Epub 2022 Sep 12; Authors: Park S, Teno JM, White L, Coe NB

• Public spending on acute and long-term care for Alzheimer's disease and related dementias.
  Alzheimer's & dementia : the journal of the Alzheimer's Association. 2023 Jan;19(1):150-157 Epub 2022 Mar 16; Authors: Coe NB, White L, Oney M, Basu A, Larson EB

• Deep label fusion: A generalizable hybrid multi-atlas and deep convolutional neural network for medical image segmentation.
  Medical image analysis. 2023 Jan;83:102683 Epub 2022 Nov 5; Authors: Xie L, Wisse LEM, Wang J, Ravikumar S, Khandelwal P, Glenn T, Luther A, Lim S, Wolk DA, Yushkevich PA

• Event-based modeling of T1-weighted MRI is related to pathology in frontotemporal lobar degeneration due to tau and TDP.
  NeuroImage. Clinical. 2023;37:103285 Epub 2022 Dec 7; Authors: Olm CA, Burke SE, Peterson C, Lee EB, Trojanowski JQ, Massimo L, Irwin DJ, Grossman M, Gee JC

• Plasma phosphorylated tau181 predicts cognitive and functional decline.
  Annals of clinical and translational neurology. 2023 Jan;10(1):18-31 Epub 2022 Dec 14; Authors: Tropea TF, Waligorska T, Xie SX, Nasrallah IM, Cousins KAQ, Trojanowski JQ, Grossman M, Irwin DJ, Weintraub D, Lee EB, Wolk DA, Chen-Plotkin AS, Shaw LM, Alzheimer's Disease Neuroimaging Initiative

• Let's Not Repeat History's Mistakes: Two Cautions to Scientists on the Use of Race in Alzheimer's Disease and Alzheimer's Disease Related Dementias Research.
  Journal of Alzheimer's disease : JAD. 2023;92(3):729-740; Authors: Stites SD, Coe NB

• ApoJ/Clusterin concentrations are determinants of cerebrospinal fluid cholesterol efflux capacity and reduced levels are associated with Alzheimer's disease.
  Alzheimer's research & therapy. 2022 Dec 26;14(1):194; Authors: Ko YA, Billheimer JT, Lyssenko NN, Kueider-Paisley A, Wolk DA, Arnold SE, Leung YY, Shaw LM, Trojanowski JQ, Kaddurah-Daouk RF, Kling MA, Rader DJ

• Optimal deep brain stimulation sites and networks for stimulation of the fornix in Alzheimer's disease.
  Nature communications. 2022 Dec 14;13(1):7707; Authors: Ríos AS, Oxenford S, Neudorfer C, Butenko K, Li N, Rajamani N, Boutet A, Elias GJB, Germann J, Loh A, Deeb W, Wang F, Setsompop K, Salvato B, Almeida LB, Foote KD, Amaral R, Rosenberg PB, Tang-Wai DF, Wolk DA, Burke AD, Salloway S, Sabbagh MN, Chakravarty MM, Smith GS, Lyketsos CG, Okun MS, Anderson WS, Mari Z, Ponce FA, Lozano AM, Horn A

• Barriers to and solutions for representative inclusion across the lifespan and in life course research: The need for structural competency highlighted by the COVID-19 pandemic.
  Journal of clinical and translational science. 2023;7(1):e38 Epub 2022 Dec 6; Authors: LeCroy MN, Potter LN, Bandeen-Roche K, Bianco ME, Cappola AR, Carter EB, Dayan PS, Eckstrom E, Edwards DF, Farabi SS, Fisher SD, Giordano J, Hanson HA, Jenkins E, Juhn Y, Kaskel F, Stake CE, Reeds DN, Schleiss MR, Wafford QE, McColley SA

• Regional distribution and maturation of tau pathology among phenotypic variants of Alzheimer's disease.
  Acta neuropathologica. 2022 Dec;144(6):1103-1116 Epub 2022 Jul 23; Authors: Arezoumandan S, Xie SX, Cousins KAQ, Mechanic-Hamilton DJ, Peterson CS, Huang CY, Ohm DT, Ittyerah R, McMillan CT, Wolk DA, Yushkevich P, Trojanowski JQ, Lee EB, Grossman M, Phillips JS, Irwin DJ

• Isoform-specific patterns of tau burden and neuronal degeneration in MAPT-associated frontotemporal lobar degeneration.
  Acta neuropathologica. 2022 Dec;144(6):1065-1084 Epub 2022 Sep 6; Authors: Giannini LAA, Ohm DT, Rozemuller AJM, Dratch L, Suh E, van Deerlin VM, Trojanowski JQ, Lee EB, van Swieten JC, Grossman M, Seelaar H, Irwin DJ, Netherlands Brain Bank

• TREM2 risk variants are associated with atypical Alzheimer's disease.
  Acta neuropathologica. 2022 Dec;144(6):1085-1102 Epub 2022 Sep 16; Authors: Kim B, Suh E, Nguyen AT, Prokop S, Mikytuck B, Olatunji OA, Robinson JL, Grossman M, Phillips JS, Irwin DJ, Mechanic-Hamilton D, Wolk DA, Trojanowski JQ, McMillan CT, Van Deerlin VM, Lee EB

• The continuing legacy of John.
  Acta neuropathologica. 2022 Dec;144(6):1063-1064 Epub 2022 Oct 27; Authors: Lee EB

• Association of Medicare Advantage Star Ratings With Racial and Ethnic Disparities in Hospitalizations for Ambulatory Care Sensitive Conditions.
  Medical care. 2022 Dec 1;60(12):872-879 Epub 2022 Nov 10; Authors: Park S, Werner RM, Coe NB

• Limbic-Predominant Age-Related TDP-43 Encephalopathy: LATE-Breaking Updates in Clinicopathologic Features and Biomarkers.
  Current neurology and neuroscience reports. 2022 Nov;22(11):689-698 Epub 2022 Oct 3; Authors: Duong MT, Wolk DA

• Distinguishing Frontotemporal Lobar Degeneration Tau From TDP-43 Using Plasma Biomarkers.
  JAMA neurology. 2022 Nov 1;79(11):1155-1164; Authors: Cousins KAQ, Shaw LM, Chen-Plotkin A, Wolk DA, Van Deerlin VM, Lee EB, McMillan CT, Grossman M, Irwin DJ

• Elevated Plasma Phosphorylated Tau 181 in Amyotrophic Lateral Sclerosis.
  Annals of neurology. 2022 Nov;92(5):807-818 Epub 2022 Aug 17; Authors: Cousins KAQ, Shaw LM, Shellikeri S, Dratch L, Rosario L, Elman LB, Quinn C, Amado DA, Wolk DA, Tropea TF, Chen-Plotkin A, Irwin DJ, Grossman M, Lee EB, Trojanowski JQ, McMillan CT

• Alzheimer's Dementia After Exposure to Anesthesia and Surgery in the Elderly: A Matched Natural Experiment Using Appendicitis.
  Annals of surgery. 2022 Nov 1;276(5):e377-e385 Epub 2020 Nov 17; Authors: Silber JH, Rosenbaum PR, Reiter JG, Hill AS, Jain S, Wolk DA, Small D, Hashemi S, Niknam BA, Neuman MD, Fleisher LA, Eckenhoff R

• Aging is associated with maladaptive episodic memory-guided social decision-making.
  Proceedings of the National Academy of Sciences of the United States of America. 2022 Oct 18;119(42):e2208681119 Epub 2022 Oct 10; Authors: Lempert KM, Cohen MS, MacNear KA, Reckers FM, Zaneski L, Wolk DA, Kable JW

• Rainwater Charitable Foundation criteria for the neuropathologic diagnosis of progressive supranuclear palsy.
  Acta neuropathologica. 2022 Oct;144(4):603-614 Epub 2022 Aug 10; Authors: Roemer SF, Grinberg LT, Crary JF, Seeley WW, McKee AC, Kovacs GG, Beach TG, Duyckaerts C, Ferrer IA, Gelpi E, Lee EB, Revesz T, White CL 3rd, Yoshida M, Pereira FL, Whitney K, Ghayal NB, Dickson DW

• Common Variants Near ZIC1 and ZIC4 in Autopsy-Confirmed Multiple System Atrophy.
  Movement disorders : official journal of the Movement Disorder Society. 2022 Oct;37(10):2110-2121 Epub 2022 Aug 23; Authors: Hopfner F, Tietz AK, Ruf VC, Ross OA, Koga S, Dickson D, Aguzzi A, Attems J, Beach T, Beller A, Cheshire WP, van Deerlin V, Desplats P, Deuschl G, Duyckaerts C, Ellinghaus D, Evsyukov V, Flanagan ME, Franke A, Frosch MP, Gearing M, Gelpi E, van Gerpen JA, Ghetti B, Glass JD, Grinberg LT, Halliday G, Helbig I, Höllerhage M, Huitinga I, Irwin DJ, Keene DC, Kovacs GG, Lee EB, Levin J, Martí MJ, Mackenzie I, McKeith I, Mclean C, Mollenhauer B, Neumann M, Newell KL, Pantelyat A, Pendziwiat M, Peters A, Molina Porcel L, Rabano A, Matěj R, Rajput A, Rajput A, Reimann R, Scott WK, Seeley W, Selvackadunco S, Simuni T, Stadelmann C, Svenningsson P, Thomas A, Trenkwalder C, Troakes C, Trojanowski JQ, Uitti RJ, White CL, Wszolek ZK, Xie T, Ximelis T, Yebenes J, Alzheimer's Disease Genetics Consortium, Müller U, Schellenberg GD, Herms J, Kuhlenbäumer G, Höglinger G

• Subclinical thyroid dysfunction and incident diabetes: a systematic review and an individual participant data analysis of prospective cohort studies.
  European journal of endocrinology. 2022 Nov 1;187(5):S35-S46 Epub 2022 Sep 30; Authors: Alwan H, Villoz F, Feller M, Dullaart RPF, Bakker SJL, Peeters RP, Kavousi M, Bauer DC, Cappola AR, Yeap BB, Walsh JP, Brown SJ, Ceresini G, Ferrucci L, Gussekloo J, Trompet S, Iacoviello M, Moon JH, Razvi S, Bensenor IM, Azizi F, Amouzegar A, Valdés S, Colomo N, Wareham NJ, Jukema JW, Westendorp RGJ, Kim KW, Rodondi N, Del Giovane C

• Observational study of patient characteristics associated with a timely diagnosis of dementia and mild cognitive impairment without dementia.
  Journal of general internal medicine. 2022 Sep;37(12):2957-2965 Epub 2021 Oct 13; Authors: White L, Ingraham B, Larson E, Fishman P, Park S, Coe NB

• Associations between shortened telomeres and rheumatoid arthritis-associated interstitial lung disease among U.S. Veterans.
  Respiratory medicine. 2022 Sep;201:106943 Epub 2022 Aug 3; Authors: Natalini JG, England BR, Baker JF, Chen Q, Singh N, Mahajan TD, Roul P, Thiele GM, Sauer BC, Mikuls TR, Johnson FB, Kawut SM

• Natural speech markers of Alzheimer's disease co-pathology in Lewy body dementias.
  Parkinsonism & related disorders. 2022 Sep;102:94-100 Epub 2022 Aug 6; Authors: Shellikeri S, Cho S, Cousins KAQ, Liberman M, Howard E, Balganorth Y, Weintraub D, Spindler M, Deik A, Lee EB, Trojanowski JQ, Irwin D, Wolk D, Grossman M, Nevler N

• GPNMB confers risk for Parkinson's disease through interaction with α-synuclein.
  Science (New York, N.Y.). 2022 Aug 19;377(6608):eabk0637; Authors: Diaz-Ortiz ME, Seo Y, Posavi M, Carceles Cordon M, Clark E, Jain N, Charan R, Gallagher MD, Unger TL, Amari N, Skrinak RT, Davila-Rivera R, Brody EM, Han N, Zack R, Van Deerlin VM, Tropea TF, Luk KC, Lee EB, Weintraub D, Chen-Plotkin AS

• Changes in the Hierarchy of Functional Impairment From Middle Age to Older Age.
  The journals of gerontology. Series A, Biological sciences and medical sciences. 2022 Aug 12;77(8):1577-1584; Authors: Brown RT, Diaz-Ramirez LG, Boscardin WJ, Cappola AR, Lee SJ, Steinman MA

• Effects of Medicare advantage on patterns of end-of-life care among Medicare decedents.
  Health services research. 2022 Aug;57(4):863-871 Epub 2022 Feb 28; Authors: Park S, Teno JM, White L, Coe NB

• Self- and Partner-Reported Subjective Memory Complaints: Association with Objective Cognitive Impairment and Risk of Decline.
  Journal of Alzheimer's disease reports. 2022;6(1):411-430 Epub 2022 Jul 22; Authors: Zuroff L, Wisse LE, Glenn T, Xie SX, Nasrallah IM, Habes M, Dubroff J, de Flores R, Xie L, Yushkevich P, Doshi J, Davatsikos C, Shaw LM, Tropea TF, Chen-Plotkin AS, Wolk DA, Das S, Mechanic-Hamilton D

• Sex Differences in Recovery Across Multiple Domains Among Older Adults With Hip Fracture.
  The journals of gerontology. Series A, Biological sciences and medical sciences. 2022 Jul 5;77(7):1463-1471; Authors: Orwig DL, Abraham DS, Hochberg MC, Gruber-Baldini A, Guralnik JM, Cappola AR, Golden J, Hicks GE, Miller RR, Resnick B, Shardell M, Sterling RS, Bajracharya R, Magaziner J

• Non-tremor motor dysfunction in Lewy body dementias is associated with AD biomarkers.
  Parkinsonism & related disorders. 2022 Jul;100:33-36 Epub 2022 Jun 8; Authors: Walker IM, Cousins KA, Siderowf A, Duda JE, Morley JF, Dahodwala N, Tropea T, Vaishnavi S, Wolk DA, Chen-Plotkin AS, Shaw LM, Lee EB, Trojanowski JQ, Grossman M, Weintraub D, Irwin DJ

• Sweetened beverage taxes: Economic benefits and costs according to household income.
  Food policy. 2022 Jul;110 Epub 2022 Jun 2; Authors: Jones-Smith JC, Knox MA, Coe NB, Walkinshaw LP, Schoof J, Hamilton D, Hurvitz PM, Krieger J

• Quantitative detection of α-Synuclein and Tau oligomers and other aggregates by digital single particle counting.
  NPJ Parkinson's disease. 2022 Jun 2;8(1):68; Authors: Blömeke L, Pils M, Kraemer-Schulien V, Dybala A, Schaffrath A, Kulawik A, Rehn F, Cousin A, Nischwitz V, Willbold J, Zack R, Tropea TF, Bujnicki T, Tamgüney G, Weintraub D, Irwin D, Grossman M, Wolk DA, Trojanowski JQ, Bannach O, Chen-Plotkin A, Willbold D

• Racial and Ethnic Disparities in Dementia Care: Next Steps.
  JAMA network open. 2022 Jun 1;5(6):e2216267; Authors: Coe NB, Lee C

• Establishing a Framework for Gathering Structural and Social Determinants of Health in Alzheimer's Disease Research Centers.
  The Gerontologist. 2022 May 26;62(5):694-703; Authors: Stites SD, Midgett S, Mechanic-Hamilton D, Zuelsdorff M, Glover CM, Marquez DX, Balls-Berry JE, Streitz ML, Babulal G, Trani JF, Henderson JN, Barnes LL, Karlawish J, Wolk DA

• The Impact of Care Intensity and Work on the Mental Health of Family Caregivers: Losses and Gains.
  The journals of gerontology. Series B, Psychological sciences and social sciences. 2022 May 20;77(Suppl_1):S98-S111; Authors: Kolodziej IWK, Coe NB, Van Houtven CH

• A tribute to John Q. Trojanowski (1946-2022).
  The Journal of clinical investigation. 2022 May 16;132(10); Authors: Irwin DJ, Lee EB

• GSK3 inhibition rescues growth and telomere dysfunction in dyskeratosis congenita iPSC-derived type II alveolar epithelial cells.
  eLife. 2022 May 13;11; Authors: Fernandez RJ, Gardner ZJG, Slovik KJ, Liberti DC, Estep KN, Yang W, Chen Q, Santini GT, Perez JV, Root S, Bhatia R, Tobias JW, Babu A, Morley MP, Frank DB, Morrisey EE, Lengner CJ, Johnson FB

• Lateralized ante mortem and post mortem pathology in a case of Lewy body disease with corticobasal syndrome.
  Alzheimer's & dementia (New York, N. Y.). 2022;8(1):e12294 Epub 2022 May 11; Authors: Coughlin DG, Coslett HB, Peterson C, Phillips JS, McMillan C, Lee EB, Trojanowski JQ, Grossman M, Irwin DJ

• Disentangling Alzheimer's disease neurodegeneration from typical brain ageing using machine learning.
  Brain communications. 2022;4(3):fcac117 Epub 2022 May 7; Authors: Hwang G, Abdulkadir A, Erus G, Habes M, Pomponio R, Shou H, Doshi J, Mamourian E, Rashid T, Bilgel M, Fan Y, Sotiras A, Srinivasan D, Morris JC, Albert MS, Bryan NR, Resnick SM, Nasrallah IM, Davatzikos C, Wolk DA, from the iSTAGING consortium, ADNI

• Divergent Histopathological Networks of Frontotemporal Degeneration Proteinopathy Subytpes.
  The Journal of neuroscience : the official journal of the Society for Neuroscience. 2022 May 4;42(18):3868-3877 Epub 2022 Mar 22; Authors: Chen M, Ohm DT, Phillips JS, McMillan CT, Capp N, Peterson C, Xie E, Wolk DA, Trojanowski JQ, Lee EB, Gee J, Grossman M, Irwin DJ

• Younger Individuals Increase Their Use of Nursing Homes Following ACA Medicaid Expansion.
  Journal of the American Medical Directors Association. 2022 May;23(5):852-857.e5 Epub 2021 Sep 21; Authors: Ritter AZ, Freed S, Coe NB

• Out-of-pocket costs attributable to dementia: A longitudinal analysis.
  Journal of the American Geriatrics Society. 2022 May;70(5):1538-1545 Epub 2022 Mar 12; Authors: Oney M, White L, Coe NB

• The methyltransferase enzymes KMT2D, SETD1B, and ASH1L are key mediators of both metabolic and epigenetic changes during cellular senescence.
  Molecular biology of the cell. 2022 May 1;33(5):ar36 Epub 2022 Feb 23; Authors: Nacarelli T, Azar A, Potnis M, Johannes G, Mell J, Johnson FB, Brown-Borg H, Noguchi E, Sell C

• Characterizing Heterogeneity in Neuroimaging, Cognition, Clinical Symptoms, and Genetics Among Patients With Late-Life Depression.
  JAMA psychiatry. 2022 May 1;79(5):464-474; Authors: Wen J, Fu CHY, Tosun D, Veturi Y, Yang Z, Abdulkadir A, Mamourian E, Srinivasan D, Skampardoni I, Singh A, Nawani H, Bao J, Erus G, Shou H, Habes M, Doshi J, Varol E, Mackin RS, Sotiras A, Fan Y, Saykin AJ, Sheline YI, Shen L, Ritchie MD, Wolk DA, Albert M, Resnick SM, Davatzikos C, iSTAGING consortium, ADNI, BIOCARD, and BLSA

• Phases of volume loss in patients with known frontotemporal lobar degeneration spectrum pathology.
  Neurobiology of aging. 2022 May;113:95-107 Epub 2022 Feb 24; Authors: Burke SE, Phillips JS, Olm CA, Peterson CS, Cook PA, Gee JC, Lee EB, Trojanowski JQ, Massimo L, Irwin DJ, Grossman M

• Dopamine neurons exhibit emergent glutamatergic identity in Parkinson's disease.
  Brain : a journal of neurology. 2022 Apr 29;145(3):879-886; Authors: Steinkellner T, Conrad WS, Kovacs I, Rissman RA, Lee EB, Trojanowski JQ, Freyberg Z, Roy S, Luk KC, Lee VM, Hnasko TS

• Addressing Online Health Privacy Risks for Older Adults: A Perspective on Ethical Considerations and Recommendations.
  Gerontology & geriatric medicine. 2022 Jan-Dec;8:23337214221095705 Epub 2022 Apr 21; Authors: Friedman AB, Pathmanabhan C, Glicksman A, Demiris G, Cappola AR, McCoy MS

• Detection of astrocytic tau pathology facilitates recognition of chronic traumatic encephalopathy neuropathologic change.
  Acta neuropathologica communications. 2022 Apr 11;10(1):50; Authors: Ameen-Ali KE, Bretzin A, Lee EB, Folkerth R, Hazrati LN, Iacono D, Keene CD, Kofler J, Kovacs GG, Nolan A, Perl DP, Priemer DS, Smith DH, Wiebe DJ, Stewart W, CONNECT-TBI Investigators

• Multimarker synaptic protein cerebrospinal fluid panels reflect TDP-43 pathology and cognitive performance in a pathological cohort of frontotemporal lobar degeneration.
  Molecular neurodegeneration. 2022 Apr 8;17(1):29; Authors: Cervantes González A, Irwin DJ, Alcolea D, McMillan CT, Chen-Plotkin A, Wolk D, Sirisi S, Dols-Icardo O, Querol-Vilaseca M, Illán-Gala I, Santos-Santos MA, Fortea J, Lee EB, Trojanowski JQ, Grossman M, Lleó A, Belbin O

• New insights into the genetic etiology of Alzheimer's disease and related dementias.
  Nature genetics. 2022 Apr;54(4):412-436 Epub 2022 Apr 4; Authors: Bellenguez C, Küçükali F, Jansen IE, Kleineidam L, Moreno-Grau S, Amin N, Naj AC, Campos-Martin R, Grenier-Boley B, Andrade V, Holmans PA, Boland A, Damotte V, van der Lee SJ, Costa MR, Kuulasmaa T, Yang Q, de Rojas I, Bis JC, Yaqub A, Prokic I, Chapuis J, Ahmad S, Giedraitis V, Aarsland D, Garcia-Gonzalez P, Abdelnour C, Alarcón-Martín E, Alcolea D, Alegret M, Alvarez I, Álvarez V, Armstrong NJ, Tsolaki A, Antúnez C, Appollonio I, Arcaro M, Archetti S, Pastor AA, Arosio B, Athanasiu L, Bailly H, Banaj N, Baquero M, Barral S, Beiser A, Pastor AB, Below JE, Benchek P, Benussi L, Berr C, Besse C, Bessi V, Binetti G, Bizarro A, Blesa R, Boada M, Boerwinkle E, Borroni B, Boschi S, Bossù P, Bråthen G, Bressler J, Bresner C, Brodaty H, Brookes KJ, Brusco LI, Buiza-Rueda D, Bûrger K, Burholt V, Bush WS, Calero M, Cantwell LB, Chene G, Chung J, Cuccaro ML, Carracedo Á, Cecchetti R, Cervera-Carles L, Charbonnier C, Chen HH, Chillotti C, Ciccone S, Claassen JAHR, Clark C, Conti E, Corma-Gómez A, Costantini E, Custodero C, Daian D, Dalmasso MC, Daniele A, Dardiotis E, Dartigues JF, de Deyn PP, de Paiva Lopes K, de Witte LD, Debette S, Deckert J, Del Ser T, Denning N, DeStefano A, Dichgans M, Diehl-Schmid J, Diez-Fairen M, Rossi PD, Djurovic S, Duron E, Düzel E, Dufouil C, Eiriksdottir G, Engelborghs S, Escott-Price V, Espinosa A, Ewers M, Faber KM, Fabrizio T, Nielsen SF, Fardo DW, Farotti L, Fenoglio C, Fernández-Fuertes M, Ferrari R, Ferreira CB, Ferri E, Fin B, Fischer P, Fladby T, Fließbach K, Fongang B, Fornage M, Fortea J, Foroud TM, Fostinelli S, Fox NC, Franco-Macías E, Bullido MJ, Frank-García A, Froelich L, Fulton-Howard B, Galimberti D, García-Alberca JM, García-González P, Garcia-Madrona S, Garcia-Ribas G, Ghidoni R, Giegling I, Giorgio G, Goate AM, Goldhardt O, Gomez-Fonseca D, González-Pérez A, Graff C, Grande G, Green E, Grimmer T, Grünblatt E, Grunin M, Gudnason V, Guetta-Baranes T, Haapasalo A, Hadjigeorgiou G, Haines JL, Hamilton-Nelson KL, Hampel H, Hanon O, Hardy J, Hartmann AM, Hausner L, Harwood J, Heilmann-Heimbach S, Helisalmi S, Heneka MT, Hernández I, Herrmann MJ, Hoffmann P, Holmes C, Holstege H, Vilas RH, Hulsman M, Humphrey J, Biessels GJ, Jian X, Johansson C, Jun GR, Kastumata Y, Kauwe J, Kehoe PG, Kilander L, Ståhlbom AK, Kivipelto M, Koivisto A, Kornhuber J, Kosmidis MH, Kukull WA, Kuksa PP, Kunkle BW, Kuzma AB, Lage C, Laukka EJ, Launer L, Lauria A, Lee CY, Lehtisalo J, Lerch O, Lleó A, Longstreth W Jr, Lopez O, de Munain AL, Love S, Löwemark M, Luckcuck L, Lunetta KL, Ma Y, Macías J, MacLeod CA, Maier W, Mangialasche F, Spallazzi M, Marquié M, Marshall R, Martin ER, Montes AM, Rodríguez CM, Masullo C, Mayeux R, Mead S, Mecocci P, Medina M, Meggy A, Mehrabian S, Mendoza S, Menéndez-González M, Mir P, Moebus S, Mol M, Molina-Porcel L, Montrreal L, Morelli L, Moreno F, Morgan K, Mosley T, Nöthen MM, Muchnik C, Mukherjee S, Nacmias B, Ngandu T, Nicolas G, Nordestgaard BG, Olaso R, Orellana A, Orsini M, Ortega G, Padovani A, Paolo C, Papenberg G, Parnetti L, Pasquier F, Pastor P, Peloso G, Pérez-Cordón A, Pérez-Tur J, Pericard P, Peters O, Pijnenburg YAL, Pineda JA, Piñol-Ripoll G, Pisanu C, Polak T, Popp J, Posthuma D, Priller J, Puerta R, Quenez O, Quintela I, Thomassen JQ, Rábano A, Rainero I, Rajabli F, Ramakers I, Real LM, Reinders MJT, Reitz C, Reyes-Dumeyer D, Ridge P, Riedel-Heller S, Riederer P, Roberto N, Rodriguez-Rodriguez E, Rongve A, Allende IR, Rosende-Roca M, Royo JL, Rubino E, Rujescu D, Sáez ME, Sakka P, Saltvedt I, Sanabria Á, Sánchez-Arjona MB, Sanchez-Garcia F, Juan PS, Sánchez-Valle R, Sando SB, Sarnowski C, Satizabal CL, Scamosci M, Scarmeas N, Scarpini E, Scheltens P, Scherbaum N, Scherer M, Schmid M, Schneider A, Schott JM, Selbæk G, Seripa D, Serrano M, Sha J, Shadrin AA, Skrobot O, Slifer S, Snijders GJL, Soininen H, Solfrizzi V, Solomon A, Song Y, Sorbi S, Sotolongo-Grau O, Spalletta G, Spottke A, Squassina A, Stordal E, Tartan JP, Tárraga L, Tesí N, Thalamuthu A, Thomas T, Tosto G, Traykov L, Tremolizzo L, Tybjærg-Hansen A, Uitterlinden A, Ullgren A, Ulstein I, Valero S, Valladares O, Broeckhoven CV, Vance J, Vardarajan BN, van der Lugt A, Dongen JV, van Rooij J, van Swieten J, Vandenberghe R, Verhey F, Vidal JS, Vogelgsang J, Vyhnalek M, Wagner M, Wallon D, Wang LS, Wang R, Weinhold L, Wiltfang J, Windle G, Woods B, Yannakoulia M, Zare H, Zhao Y, Zhang X, Zhu C, Zulaica M, EADB, GR@ACE, DEGESCO, EADI, GERAD, Demgene, FinnGen, ADGC, CHARGE, Farrer LA, Psaty BM, Ghanbari M, Raj T, Sachdev P, Mather K, Jessen F, Ikram MA, de Mendonça A, Hort J, Tsolaki M, Pericak-Vance MA, Amouyel P, Williams J, Frikke-Schmidt R, Clarimon J, Deleuze JF, Rossi G, Seshadri S, Andreassen OA, Ingelsson M, Hiltunen M, Sleegers K, Schellenberg GD, van Duijn CM, Sims R, van der Flier WM, Ruiz A, Ramirez A, Lambert JC

• Risk of Parkinson's disease after anaesthesia and surgery.
  British journal of anaesthesia. 2022 Apr;128(4):e268-e270 Epub 2022 Jan 29; Authors: Jain S, Rosenbaum PR, Reiter JG, Hill AS, Wolk DA, Hashemi S, Fleisher LA, Eckenhoff R, Silber JH

• John Q. Trojanowski: neuropathology icon.
  Acta neuropathologica. 2022 Apr;143(4):419-425 Epub 2022 Mar 22; Authors: Lee EB

• Combining plasma phospho-tau and accessible measures to evaluate progression to Alzheimer's dementia in mild cognitive impairment patients.
  Alzheimer's research & therapy. 2022 Mar 29;14(1):46; Authors: Pichet Binette A, Palmqvist S, Bali D, Farrar G, Buckley CJ, Wolk DA, Zetterberg H, Blennow K, Janelidze S, Hansson O

• Dissociation of tau pathology and neuronal hypometabolism within the ATN framework of Alzheimer's disease.
  Nature communications. 2022 Mar 21;13(1):1495; Authors: Duong MT, Das SR, Lyu X, Xie L, Richardson H, Xie SX, Yushkevich PA, Alzheimer’s Disease Neuroimaging Initiative (ADNI), Wolk DA, Nasrallah IM

• Tau deposition patterns are associated with functional connectivity in primary tauopathies.
  Nature communications. 2022 Mar 15;13(1):1362; Authors: Franzmeier N, Brendel M, Beyer L, Slemann L, Kovacs GG, Arzberger T, Kurz C, Respondek G, Lukic MJ, Biel D, Rubinski A, Frontzkowski L, Hummel S, Müller A, Finze A, Palleis C, Joseph E, Weidinger E, Katzdobler S, Song M, Biechele G, Kern M, Scheifele M, Rauchmann BS, Perneczky R, Rullman M, Patt M, Schildan A, Barthel H, Sabri O, Rumpf JJ, Schroeter ML, Classen J, Villemagne V, Seibyl J, Stephens AW, Lee EB, Coughlin DG, Giese A, Grossman M, McMillan CT, Gelpi E, Molina-Porcel L, Compta Y, van Swieten JC, Laat LD, Troakes C, Al-Sarraj S, Robinson JL, Xie SX, Irwin DJ, Roeber S, Herms J, Simons M, Bartenstein P, Lee VM, Trojanowski JQ, Levin J, Höglinger G, Ewers M

• TMEM106B deficiency impairs cerebellar myelination and synaptic integrity with Purkinje cell loss.
  Acta neuropathologica communications. 2022 Mar 14;10(1):33; Authors: Feng T, Luan L, Katz II, Ullah M, Van Deerlin VM, Trojanowski JQ, Lee EB, Hu F

• Application of predictive models in boosting power of Alzheimer's disease clinical trials: A post hoc analysis of phase 3 solanezumab trials.
  Alzheimer's & dementia (New York, N. Y.). 2022;8(1):e12223 Epub 2022 Mar 14; Authors: Ezzati A, Davatzikos C, Wolk DA, Hall CB, Habeck C, Lipton RB

• Medial Temporal Lobe Networks in Alzheimer's Disease: Structural and Molecular Vulnerabilities.
  The Journal of neuroscience : the official journal of the Society for Neuroscience. 2022 Mar 9;42(10):2131-2141 Epub 2022 Jan 27; Authors: de Flores R, Das SR, Xie L, Wisse LEM, Lyu X, Shah P, Yushkevich PA, Wolk DA

• Signature laminar distributions of pathology in frontotemporal lobar degeneration.
  Acta neuropathologica. 2022 Mar;143(3):363-382 Epub 2022 Jan 8; Authors: Ohm DT, Cousins KAQ, Xie SX, Peterson C, McMillan CT, Massimo L, Raskovsky K, Wolk DA, Van Deerlin VM, Elman L, Spindler M, Deik A, Trojanowski JQ, Lee EB, Grossman M, Irwin DJ

• Prevalence Estimates of Amyloid Abnormality Across the Alzheimer Disease Clinical Spectrum.
  JAMA neurology. 2022 Mar 1;79(3):228-243; Authors: Jansen WJ, Janssen O, Tijms BM, Vos SJB, Ossenkoppele R, Visser PJ, Amyloid Biomarker Study Group, Aarsland D, Alcolea D, Altomare D, von Arnim C, Baiardi S, Baldeiras I, Barthel H, Bateman RJ, Van Berckel B, Binette AP, Blennow K, Boada M, Boecker H, Bottlaender M, den Braber A, Brooks DJ, Van Buchem MA, Camus V, Carill JM, Cerman J, Chen K, Chételat G, Chipi E, Cohen AD, Daniels A, Delarue M, Didic M, Drzezga A, Dubois B, Eckerström M, Ekblad LL, Engelborghs S, Epelbaum S, Fagan AM, Fan Y, Fladby T, Fleisher AS, Van der Flier WM, Förster S, Fortea J, Frederiksen KS, Freund-Levi Y, Frings L, Frisoni GB, Fröhlich L, Gabryelewicz T, Gertz HJ, Gill KD, Gkatzima O, Gómez-Tortosa E, Grimmer T, Guedj E, Habeck CG, Hampel H, Handels R, Hansson O, Hausner L, Hellwig S, Heneka MT, Herukka SK, Hildebrandt H, Hodges J, Hort J, Huang CC, Iriondo AJ, Itoh Y, Ivanoiu A, Jagust WJ, Jessen F, Johannsen P, Johnson KA, Kandimalla R, Kapaki EN, Kern S, Kilander L, Klimkowicz-Mrowiec A, Klunk WE, Koglin N, Kornhuber J, Kramberger MG, Kuo HC, Van Laere K, Landau SM, Landeau B, Lee DY, de Leon M, Leyton CE, Lin KJ, Lleó A, Löwenmark M, Madsen K, Maier W, Marcusson J, Marquié M, Martinez-Lage P, Maserejian N, Mattsson N, de Mendonça A, Meyer PT, Miller BL, Minatani S, Mintun MA, Mok VCT, Molinuevo JL, Morbelli SD, Morris JC, Mroczko B, Na DL, Newberg A, Nobili F, Nordberg A, Olde Rikkert MGM, de Oliveira CR, Olivieri P, Orellana A, Paraskevas G, Parchi P, Pardini M, Parnetti L, Peters O, Poirier J, Popp J, Prabhakar S, Rabinovici GD, Ramakers IH, Rami L, Reiman EM, Rinne JO, Rodrigue KM, Rodríguez-Rodriguez E, Roe CM, Rosa-Neto P, Rosen HJ, Rot U, Rowe CC, Rüther E, Ruiz A, Sabri O, Sakhardande J, Sánchez-Juan P, Sando SB, Santana I, Sarazin M, Scheltens P, Schröder J, Selnes P, Seo SW, Silva D, Skoog I, Snyder PJ, Soininen H, Sollberger M, Sperling RA, Spiru L, Stern Y, Stomrud E, Takeda A, Teichmann M, Teunissen CE, Thompson LI, Tomassen J, Tsolaki M, Vandenberghe R, Verbeek MM, Verhey FRJ, Villemagne V, Villeneuve S, Vogelgsang J, Waldemar G, Wallin A, Wallin ÅK, Wiltfang J, Wolk DA, Yen TC, Zboch M, Zetterberg H

• Deep Generative Medical Image Harmonization for Improving Cross-Site Generalization in Deep Learning Predictors.
  Journal of magnetic resonance imaging : JMRI. 2022 Mar;55(3):908-916 Epub 2021 Sep 25; Authors: Bashyam VM, Doshi J, Erus G, Srinivasan D, Abdulkadir A, Singh A, Habes M, Fan Y, Masters CL, Maruff P, Zhuo C, Völzke H, Johnson SC, Fripp J, Koutsouleris N, Satterthwaite TD, Wolf DH, Gur RE, Gur RC, Morris JC, Albert MS, Grabe HJ, Resnick SM, Bryan NR, Wittfeld K, Bülow R, Wolk DA, Shou H, Nasrallah IM, Davatzikos C, iSTAGING and PHENOM consortia

• Incorporating Baseline Outcome Data in Individual Participant Data Meta-Analysis of Non-randomized Studies.
  Frontiers in psychiatry. 2022;13:774251 Epub 2022 Feb 22; Authors: Syrogiannouli L, Wildisen L, Meuwese C, Bauer DC, Cappola AR, Gussekloo J, den Elzen WPJ, Trompet S, Westendorp RGJ, Jukema JW, Ferrucci L, Ceresini G, Åsvold BO, Chaker L, Peeters RP, Imaizumi M, Ohishi W, Vaes B, Völzke H, Sgarbi JA, Walsh JP, Dullaart RPF, Bakker SJL, Iacoviello M, Rodondi N, Del Giovane C

• Subclinical hypothyroidism in older individuals.
  The lancet. Diabetes & endocrinology. 2022 Feb;10(2):129-141 Epub 2021 Dec 22; Authors: Biondi B, Cappola AR

• Evaluation and disposition of older adults presenting to the emergency department with abdominal pain.
  Journal of the American Geriatrics Society. 2022 Feb;70(2):501-511 Epub 2021 Oct 10; Authors: Friedman AB, Chen AT, Wu R, Coe NB, Halpern SD, Hwang U, Kelz RR, Cappola AR

• Osteoporosis, Rather Than Sarcopenia, Is the Predominant Musculoskeletal Disease in a Rural South African Community Where Human Immunodeficiency Virus Prevalence Is High: A Cross-Sectional Study.
  Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research. 2022 Feb;37(2):244-255 Epub 2021 Nov 23; Authors: Gregson CL, Madanhire T, Rehman A, Ferrand RA, Cappola AR, Tollman S, Mokoena T, ARK Consortium, Micklesfield LK, Wade AN, Fabian J

• Challenges in the Management of Atrial Fibrillation With Subclinical Hyperthyroidism.
  Frontiers in endocrinology. 2021;12:795492 Epub 2022 Jan 4; Authors: Gencer B, Cappola AR, Rodondi N, Collet TH

• Distinct characteristics of limbic-predominant age-related TDP-43 encephalopathy in Lewy body disease.
  Acta neuropathologica. 2022 Jan;143(1):15-31 Epub 2021 Dec 2; Authors: Uemura MT, Robinson JL, Cousins KAQ, Tropea TF, Kargilis DC, McBride JD, Suh E, Xie SX, Xu Y, Porta S, Uemura N, Van Deerlin VM, Wolk DA, Irwin DJ, Brunden KR, Lee VM, Lee EB, Trojanowski JQ

• Diagnosing Mild Cognitive Impairment Among Racially Diverse Older Adults: Comparison of Consensus, Actuarial, and Statistical Methods.
  Journal of Alzheimer's disease : JAD. 2022;85(2):627-644; Authors: Devlin KN, Brennan L, Saad L, Giovannetti T, Hamilton RH, Wolk DA, Xie SX, Mechanic-Hamilton D

• Ex vivo MRI and histopathology detect novel iron-rich cortical inflammation in frontotemporal lobar degeneration with tau versus TDP-43 pathology.
  NeuroImage. Clinical. 2022;33:102913 Epub 2021 Dec 14; Authors: Tisdall MD, Ohm DT, Lobrovich R, Das SR, Mizsei G, Prabhakaran K, Ittyerah R, Lim S, McMillan CT, Wolk DA, Gee J, Trojanowski JQ, Lee EB, Detre JA, Yushkevich P, Grossman M, Irwin DJ

• Informal Caregivers Provide Considerable Front-Line Support In Residential Care Facilities And Nursing Homes.
  Health affairs (Project Hope). 2022 Jan;41(1):105-111; Authors: Coe NB, Werner RM

• Cerebrovascular disease lesions are additive and tied to vascular risk factors and cognitive impairment.
  Free neuropathology. 2022;3 Epub 2022 Mar 14; Authors: Robinson JL, Richardson H, Xie SX, Alfaro B, Loh N, Lee VM, Lee EB, Trojanowski JQ

• Genome-wide association study and functional validation implicates JADE1 in tauopathy.
  Acta neuropathologica. 2022 Jan;143(1):33-53 Epub 2021 Nov 1; Authors: Farrell K, Kim S, Han N, Iida MA, Gonzalez EM, Otero-Garcia M, Walker JM, Richardson TE, Renton AE, Andrews SJ, Fulton-Howard B, Humphrey J, Vialle RA, Bowles KR, de Paiva Lopes K, Whitney K, Dangoor DK, Walsh H, Marcora E, Hefti MM, Casella A, Sissoko CT, Kapoor M, Novikova G, Udine E, Wong G, Tang W, Bhangale T, Hunkapiller J, Ayalon G, Graham RR, Cherry JD, Cortes EP, Borukov VY, McKee AC, Stein TD, Vonsattel JP, Teich AF, Gearing M, Glass J, Troncoso JC, Frosch MP, Hyman BT, Dickson DW, Murray ME, Attems J, Flanagan ME, Mao Q, Mesulam MM, Weintraub S, Woltjer RL, Pham T, Kofler J, Schneider JA, Yu L, Purohit DP, Haroutunian V, Hof PR, Gandy S, Sano M, Beach TG, Poon W, Kawas CH, Corrada MM, Rissman RA, Metcalf J, Shuldberg S, Salehi B, Nelson PT, Trojanowski JQ, Lee EB, Wolk DA, McMillan CT, Keene CD, Latimer CS, Montine TJ, Kovacs GG, Lutz MI, Fischer P, Perrin RJ, Cairns NJ, Franklin EE, Cohen HT, Raj T, Cobos I, Frost B, Goate A, White Iii CL, Crary JF

• Tau pathology mediates age effects on medial temporal lobe structure.
  Neurobiology of aging. 2022 Jan;109:135-144 Epub 2021 Sep 24; Authors: Wisse LE, Xie L, Das SR, de Flores R, Hansson O, Habes M, Doshi J, Davatzikos C, Yushkevich PA, Wolk DA, Alzheimers Disease Neuroimaging Initiative

• Induction of IL19 expression through JNK and cGAS-STING modulates DNA damage-induced cytokine production.
  Science signaling. 2021 Dec 21;14(714):eaba2611; Authors: Small SH, Tang EJ, Ragland RL, Ruzankina Y, Schoppy DW, Mandal RS, Glineburg MR, Ustelenca Z, Powell DJ, Simpkins F, Johnson FB, Brown EJ

• A deep learning framework identifies dimensional representations of Alzheimer's Disease from brain structure.
  Nature communications. 2021 Dec 3;12(1):7065; Authors: Yang Z, Nasrallah IM, Shou H, Wen J, Doshi J, Habes M, Erus G, Abdulkadir A, Resnick SM, Albert MS, Maruff P, Fripp J, Morris JC, Wolk DA, Davatzikos C, iSTAGING Consortium, Baltimore Longitudinal Study of Aging (BLSA), Alzheimer’s Disease Neuroimaging Initiative (ADNI)

• Association of Medicare Advantage Penetration With Per Capita Spending, Emergency Department Visits, and Readmission Rates Among Fee-for-Service Medicare Beneficiaries With High Comorbidity Burden.
  Medical care research and review : MCRR. 2021 Dec;78(6):703-712 Epub 2020 Aug 26; Authors: Park S, Langellier BA, Burke RE, Figueroa JF, Coe NB

• Distinct brain-derived TDP-43 strains from FTLD-TDP subtypes induce diverse morphological TDP-43 aggregates and spreading patterns in vitro and in vivo.
  Neuropathology and applied neurobiology. 2021 Dec;47(7):1033-1049 Epub 2021 May 21; Authors: Porta S, Xu Y, Lehr T, Zhang B, Meymand E, Olufemi M, Stieber A, Lee EB, Trojanowski JQ, Lee VM

• Statewide Evaluation of Washington's State Innovation Model Initiative: A Mixed-Methods Approach.
  Population health management. 2021 Dec;24(6):727-737 Epub 2021 May 19; Authors: Grembowski D, Ingraham B, Wood S, Coe NB, Fishman P, Conrad DA

• The Longitudinal Early-onset Alzheimer's Disease Study (LEADS): Framework and methodology.
  Alzheimer's & dementia : the journal of the Alzheimer's Association. 2021 Dec;17(12):2043-2055 Epub 2021 May 21; Authors: Apostolova LG, Aisen P, Eloyan A, Fagan A, Fargo KN, Foroud T, Gatsonis C, Grinberg LT, Jack CR Jr, Kramer J, Koeppe R, Kukull WA, Murray ME, Nudelman K, Rumbaugh M, Toga A, Vemuri P, Trullinger A, Iaccarino L, Day GS, Graff-Radford NR, Honig LS, Jones DT, Masdeu J, Mendez M, Musiek E, Onyike CU, Rogalski E, Salloway S, Wolk DA, Wingo TS, Carrillo MC, Dickerson BC, Rabinovici GD, LEADS Consortium

• Neurofilament Light Chain as a Biomarker for Cognitive Decline in Parkinson Disease.
  Movement disorders : official journal of the Movement Disorder Society. 2021 Dec;36(12):2945-2950 Epub 2021 Sep 4; Authors: Aamodt WW, Waligorska T, Shen J, Tropea TF, Siderowf A, Weintraub D, Grossman M, Irwin D, Wolk DA, Xie SX, Trojanowski JQ, Shaw LM, Chen-Plotkin AS

• Retina tissue validation of optical coherence tomography determined outer nuclear layer loss in FTLD-tau.
  Acta neuropathologica communications. 2021 Nov 18;9(1):184; Authors: Kim BJ, Lee V, Lee EB, Saludades A, Trojanowski JQ, Dunaief JL, Grossman M, Irwin DJ

• Trends in Receipt of Help at Home After Hospital Discharge Among Older Adults in the US.
  JAMA network open. 2021 Nov 1;4(11):e2135346; Authors: Bressman E, Coe NB, Chen X, Konetzka RT, Werner RM

• Racial Disparities in Avoidable Hospitalizations in Traditional Medicare and Medicare Advantage.
  Medical care. 2021 Nov 1;59(11):989-996; Authors: Park S, Fishman P, Coe NB

• DeepAtrophy: Teaching a neural network to detect progressive changes in longitudinal MRI of the hippocampal region in Alzheimer's disease.
  NeuroImage. 2021 Nov;243:118514 Epub 2021 Aug 24; Authors: Dong M, Xie L, Das SR, Wang J, Wisse LEM, deFlores R, Wolk DA, Yushkevich PA, Alzheimer's Disease Neuroimaging Initiative

• Association of Thyroid Dysfunction With Cognitive Function: An Individual Participant Data Analysis.
  JAMA internal medicine. 2021 Nov 1;181(11):1440-1450; Authors: van Vliet NA, van Heemst D, Almeida OP, Åsvold BO, Aubert CE, Bae JB, Barnes LE, Bauer DC, Blauw GJ, Brayne C, Cappola AR, Ceresini G, Comijs HC, Dartigues JF, Degryse JM, Dullaart RPF, van Eersel MEA, den Elzen WPJ, Ferrucci L, Fink HA, Flicker L, Grabe HJ, Han JW, Helmer C, Huisman M, Ikram MA, Imaizumi M, de Jongh RT, Jukema JW, Kim KW, Kuller LH, Lopez OL, Mooijaart SP, Moon JH, Moutzouri E, Nauck M, Parle J, Peeters RP, Samuels MH, Schmidt CO, Schminke U, Slagboom PE, Stordal E, Vaes B, Völzke H, Westendorp RGJ, Yamada M, Yeap BB, Rodondi N, Gussekloo J, Trompet S, Thyroid Studies Collaboration

• Do the telomere ends justify the physical means?
  Journal of the American Geriatrics Society. 2021 Nov;69(11):3071-3073 Epub 2021 Sep 17; Authors: Pignolo RJ, Johnson FB

• Astrocyte activation imaging with 11C-acetate and amyloid PET in mild cognitive impairment due to Alzheimer pathology.
  Nuclear medicine communications. 2021 Nov 1;42(11):1261-1269; Authors: Duong MT, Chen YJ, Doot RK, Young AJ, Lee H, Cai J, Pilania A, Wolk DA, Nasrallah IM

• Tau-Atrophy Variability Reveals Phenotypic Heterogeneity in Alzheimer's Disease.
  Annals of neurology. 2021 Nov;90(5):751-762 Epub 2021 Oct 15; Authors: Das SR, Lyu X, Duong MT, Xie L, McCollum L, de Flores R, DiCalogero M, Irwin DJ, Dickerson BC, Nasrallah IM, Yushkevich PA, Wolk DA, Alzheimer's Disease Neuroimaging Initiative

• SpaGCN: Integrating gene expression, spatial location and histology to identify spatial domains and spatially variable genes by graph convolutional network.
  Nature methods. 2021 Nov;18(11):1342-1351 Epub 2021 Oct 28; Authors: Hu J, Li X, Coleman K, Schroeder A, Ma N, Irwin DJ, Lee EB, Shinohara RT, Li M

• Ex vivo MRI atlas of the human medial temporal lobe: characterizing neurodegeneration due to tau pathology.
  Acta neuropathologica communications. 2021 Oct 24;9(1):173; Authors: Ravikumar S, Wisse LEM, Lim S, Ittyerah R, Xie L, Bedard ML, Das SR, Lee EB, Tisdall MD, Prabhakaran K, Lane J, Detre JA, Mizsei G, Trojanowski JQ, Robinson JL, Schuck T, Grossman M, Artacho-Pérula E, de Onzoño Martin MMI, Del Mar Arroyo Jiménez M, Muñoz M, Romero FJM, Del Pilar Marcos Rabal M, Sánchez SC, González JCD, de la Rosa Prieto C, Parada MC, Irwin DJ, Wolk DA, Insausti R, Yushkevich PA

• Mapping autonomic, mood and cognitive effects of hypothalamic region deep brain stimulation.
  Brain : a journal of neurology. 2021 Oct 22;144(9):2837-2851; Authors: Neudorfer C, Elias GJB, Jakobs M, Boutet A, Germann J, Narang K, Loh A, Paff M, Horn A, Kucharczyk W, Deeb W, Salvato B, Almeida L, Foote KD, Rosenberg PB, Tang-Wai DF, Anderson WS, Mari Z, Ponce FA, Wolk DA, Burke AD, Salloway S, Sabbagh MN, Chakravarty MM, Smith GS, Lyketsos CG, Okun MS, Lozano AM

• Three-dimensional mapping of neurofibrillary tangle burden in the human medial temporal lobe.
  Brain : a journal of neurology. 2021 Oct 22;144(9):2784-2797; Authors: Yushkevich PA, Muñoz López M, Iñiguez de Onzoño Martin MM, Ittyerah R, Lim S, Ravikumar S, Bedard ML, Pickup S, Liu W, Wang J, Hung LY, Lasserve J, Vergnet N, Xie L, Dong M, Cui S, McCollum L, Robinson JL, Schuck T, de Flores R, Grossman M, Tisdall MD, Prabhakaran K, Mizsei G, Das SR, Artacho-Pérula E, Arroyo Jiménez MDM, Marcos Raba MP, Molina Romero FJ, Cebada Sánchez S, Delgado González JC, de la Rosa-Prieto C, Córcoles Parada M, Lee EB, Trojanowski JQ, Ohm DT, Wisse LEM, Wolk DA, Irwin DJ, Insausti R

• TMEM106B modifies TDP-43 pathology in human ALS brain and cell-based models of TDP-43 proteinopathy.
  Acta neuropathologica. 2021 Oct;142(4):629-642 Epub 2021 Jun 21; Authors: Mao F, Robinson JL, Unger T, Posavi M, Amado DA, Elman L, Grossman M, Wolk DA, Lee EB, Van Deerlin VM, Porta S, Lee VMY, Trojanowski JQ, Chen-Plotkin AS

• TDP-43 mediates SREBF2-regulated gene expression required for oligodendrocyte myelination.
  The Journal of cell biology. 2021 Sep 6;220(9) Epub 2021 Aug 4; Authors: Ho WY, Chang JC, Lim K, Cazenave-Gassiot A, Nguyen AT, Foo JC, Muralidharan S, Viera-Ortiz A, Ong SJM, Hor JH, Agrawal I, Hoon S, Arogundade OA, Rodriguez MJ, Lim SM, Kim SH, Ravits J, Ng SY, Wenk MR, Lee EB, Tucker-Kellogg G, Ling SC

• Predictors of cognitive impairment in primary age-related tauopathy: an autopsy study.
  Acta neuropathologica communications. 2021 Aug 5;9(1):134; Authors: Iida MA, Farrell K, Walker JM, Richardson TE, Marx GA, Bryce CH, Purohit D, Ayalon G, Beach TG, Bigio EH, Cortes EP, Gearing M, Haroutunian V, McMillan CT, Lee EB, Dickson DW, McKee AC, Stein TD, Trojanowski JQ, Woltjer RL, Kovacs GG, Kofler JK, Kaye J, White CL 3rd, Crary JF

• The one-year impact of accountable care networks among Washington State employees.
  Health services research. 2021 Aug;56(4):604-614 Epub 2021 Apr 16; Authors: Coe NB, Ingraham B, Albertson E, Zhou L, Wood S, Grembowski D, Conrad D

• Tau immunotherapy is associated with glial responses in FTLD-tau.
  Acta neuropathologica. 2021 Aug;142(2):243-257 Epub 2021 May 5; Authors: Kim B, Mikytuck B, Suh E, Gibbons GS, Van Deerlin VM, Vaishnavi SN, Spindler MA, Massimo L, Grossman M, Trojanowski JQ, Irwin DJ, Lee EB

• Interactions between ALS-linked FUS and nucleoporins are associated with defects in the nucleocytoplasmic transport pathway.
  Nature neuroscience. 2021 Aug;24(8):1077-1088 Epub 2021 May 31; Authors: Lin YC, Kumar MS, Ramesh N, Anderson EN, Nguyen AT, Kim B, Cheung S, McDonough JA, Skarnes WC, Lopez-Gonzalez R, Landers JE, Fawzi NL, Mackenzie IRA, Lee EB, Nickerson JA, Grunwald D, Pandey UB, Bosco DA

• Downstream effects of polypathology on neurodegeneration of medial temporal lobe subregions.
  Acta neuropathologica communications. 2021 Jul 21;9(1):128; Authors: Wisse LEM, Ravikumar S, Ittyerah R, Lim S, Lane J, Bedard ML, Xie L, Das SR, Schuck T, Grossman M, Lee EB, Tisdall MD, Prabhakaran K, Detre JA, Mizsei G, Trojanowski JQ, Artacho-Pérula E, de Iñiguez de Onzono Martin MM, M Arroyo-Jiménez M, Muñoz Lopez M, Molina Romero FJ, P Marcos Rabal M, Cebada Sánchez S, Delgado González JC, de la Rosa Prieto C, Córcoles Parada M, Wolk DA, Irwin DJ, Insausti R, Yushkevich PA

• Sex-specific 25-hydroxyvitamin D threshold concentrations for functional outcomes in older adults: PRoject on Optimal VItamin D in Older adults (PROVIDO).
  The American journal of clinical nutrition. 2021 Jul 1;114(1):16-28; Authors: Shardell M, Cappola AR, Guralnik JM, Hicks GE, Kritchevsky SB, Simonsick EM, Ferrucci L, Semba RD, Shaffer NC, Harris T, Eiriksdottir G, Gudnason V, Cotch MF, Orwoll E, Ensrud KE, Cawthon PM

• Chronic Care, Dementia Care Management, and Financial Considerations.
  Journal of the American Medical Directors Association. 2021 Jul;22(7):1371-1376 Epub 2021 May 31; Authors: Coe NB, Boyd CM, Chodosh J

• Concordance between fasting plasma glucose and HbA(1c) in the diagnosis of diabetes in black South African adults: a cross-sectional study.
  BMJ open. 2021 Jun 17;11(6):e046060; Authors: Wade AN, Crowther NJ, Abrahams-Gessel S, Berkman L, George JA, Gómez-Olivé FX, Manne-Goehler J, Salomon JA, Wagner RG, Gaziano TA, Tollman SM, Cappola AR

• Autoimmune Thyroid Disease in Women.
  JAMA. 2021 Jun 15;325(23):2392-2393; Authors: Mammen JSR, Cappola AR

• The Cryo-EM Effect: Structural Biology of Neurodegenerative Disease Proteostasis Factors.
  Journal of neuropathology and experimental neurology. 2021 Jun 4;80(6):494-513; Authors: Creekmore BC, Chang YW, Lee EB

• The Cryo-EM Effect: Structural Biology of Neurodegenerative Disease Aggregates.
  Journal of neuropathology and experimental neurology. 2021 Jun 4;80(6):514-529; Authors: Creekmore BC, Chang YW, Lee EB

• Demographic Characteristics Driving Disparities in Receipt of Long-term Services and Supports in the Community Setting.
  Medical care. 2021 Jun 1;59(6):537-542; Authors: Travers JL, Naylor MD, Coe NB, Meng C, Li F, Cohen AB

• Effect of Targeted Messaging on Return to In-Person Visits During the COVID-19 Pandemic: A Randomized Clinical Trial.
  JAMA network open. 2021 Jun 1;4(6):e2115211; Authors: Cappola AR, Schriver ER, Mowery DL, Wollack C, Ives CT, Gonzales R, Cappella JN

• Pathological drivers of neurodegeneration in suspected non-Alzheimer's disease pathophysiology.
  Alzheimer's research & therapy. 2021 May 14;13(1):100; Authors: Wisse LEM, de Flores R, Xie L, Das SR, McMillan CT, Trojanowski JQ, Grossman M, Lee EB, Irwin D, Yushkevich PA, Wolk DA, Alzheimer’s Disease NeuroImaging Initiative

• ATN incorporating cerebrospinal fluid neurofilament light chain detects frontotemporal lobar degeneration.
  Alzheimer's & dementia : the journal of the Alzheimer's Association. 2021 May;17(5):822-830 Epub 2020 Nov 23; Authors: Cousins KAQ, Phillips JS, Irwin DJ, Lee EB, Wolk DA, Shaw LM, Zetterberg H, Blennow K, Burke SE, Kinney NG, Gibbons GS, McMillan CT, Trojanowski JQ, Grossman M

• Brain structures and networks responsible for stimulation-induced memory flashbacks during forniceal deep brain stimulation for Alzheimer's disease.
  Alzheimer's & dementia : the journal of the Alzheimer's Association. 2021 May;17(5):777-787 Epub 2021 Jan 21; Authors: Germann J, Elias GJB, Boutet A, Narang K, Neudorfer C, Horn A, Loh A, Deeb W, Salvato B, Almeida L, Foote KD, Rosenberg PB, Tang-Wai DF, Wolk DA, Burke AD, Salloway S, Sabbagh MN, Chakravarty MM, Smith GS, Lyketsos CG, Okun MS, Lozano AM

• Association of Intensive vs Standard Blood Pressure Control With Magnetic Resonance Imaging Biomarkers of Alzheimer Disease: Secondary Analysis of the SPRINT MIND Randomized Trial.
  JAMA neurology. 2021 May 1;78(5):568-577; Authors: Nasrallah IM, Gaussoin SA, Pomponio R, Dolui S, Erus G, Wright CB, Launer LJ, Detre JA, Wolk DA, Davatzikos C, Williamson JD, Pajewski NM, Bryan RN, SPRINT Research Group

• Nursing Home Staffing Levels Did Not Change Significantly During COVID-19.
  Health affairs (Project Hope). 2021 May;40(5):795-801; Authors: Werner RM, Coe NB

• Cortisol and Dehydroepiandrosterone Response to Adrenocorticotropic Hormone and Frailty in Older Women.
  The journals of gerontology. Series A, Biological sciences and medical sciences. 2021 Apr 30;76(5):901-905; Authors: Le NP, Varadhan R, Fried LP, Cappola AR

• The USPSTF 2021 Recommendations on Screening for Asymptomatic Vitamin D Deficiency in Adults: The Challenge for Clinicians Continues.
  JAMA. 2021 Apr 13;325(14):1401-1402; Authors: Burnett-Bowie SM, Cappola AR

• The development and convergence of co-pathologies in Alzheimer's disease.
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• Cognitive Profile and Markers of Alzheimer Disease-Type Pathology in Patients With Lewy Body Dementias.
  Neurology. 2021 Apr 6;96(14):e1855-e1864 Epub 2021 Feb 16; Authors: Howard E, Irwin DJ, Rascovsky K, Nevler N, Shellikeri S, Tropea TF, Spindler M, Deik A, Chen-Plotkin A, Siderowf A, Dahodwala N, Weintraub D, Shaw LM, Trojanowski JQ, Vaishnavi SN, Wolk DA, Mechanic-Hamilton D, Morley JF, Duda JE, Grossman M, Cousins KAQ

• Difficulty with Taking Medications Is Associated with Future Diagnosis of Alzheimer's Disease and Related Dementias.
  Journal of general internal medicine. 2021 Apr;36(4):863-868 Epub 2020 Oct 9; Authors: Barthold D, Marcum ZA, Chen S, White L, Ailabouni N, Basu A, Coe NB, Gray SL

• The Effects of Home Care Provider Mix on the Care Recipient: An International, Systematic Review of Articles from 2000 to 2020.
  Annual review of public health. 2021 Apr 1;42:483-503 Epub 2021 Jan 4; Authors: Coe NB, Konetzka RT, Berkowitz M, Blecker E, Van Houtven CH

• Successful transatlantic bilateral hand transplant in a young female highly sensitized to HLA class II antigens.
  Transplant immunology. 2021 Apr;65:101377 Epub 2021 Feb 18; Authors: Azoury SC, Johnson FB, Levine M, Veasey S, McAndrew C, Shaked A, Lantieri L, Kamoun M, Levin LS

• Neurofilament Light Chain Related to Longitudinal Decline in Frontotemporal Lobar Degeneration.
  Neurology. Clinical practice. 2021 Apr;11(2):105-116; Authors: Zhang JV, Irwin DJ, Blennow K, Zetterberg H, Lee EB, Shaw LM, Rascovsky K, Massimo L, McMillan CT, Chen-Plotkin A, Elman L, Lee VM, McCluskey L, Toledo JB, Weintraub D, Wolk D, Trojanowski JQ, Grossman M

• Cholesterol, Atherosclerosis, and APOE in Vascular Contributions to Cognitive Impairment and Dementia (VCID): Potential Mechanisms and Therapy.
  Frontiers in aging neuroscience. 2021;13:647990 Epub 2021 Mar 25; Authors: Duong MT, Nasrallah IM, Wolk DA, Chang CCY, Chang TY

• Local Health Jurisdiction Staff Deliver Health Promotion to Small Worksites, Washington.
  Journal of public health management and practice : JPHMP. 2021 Mar-Apr 01;27(2):117-124; Authors: Harris JR, Hammerback K, Brown M, Ryan DE, Coe NB, Pike KJ, Santiago PM, Hannon PA

• COllaborative Neuropathology NEtwork Characterizing ouTcomes of TBI (CONNECT-TBI).
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• Evidence-Based Use of Levothyroxine/Liothyronine Combinations in Treating Hypothyroidism: A Consensus Document.
  European thyroid journal. 2021 Mar;10(1):10-38 Epub 2021 Feb 16; Authors: Jonklaas J, Bianco AC, Cappola AR, Celi FS, Fliers E, Heuer H, McAninch EA, Moeller LC, Nygaard B, Sawka AM, Watt T, Dayan CM

• Author Correction: Determinants of response and resistance to CD19 chimeric antigen receptor (CAR) T cell therapy of chronic lymphocytic leukemia.
  Nature medicine. 2021 Mar;27(3):561; Authors: Fraietta JA, Lacey SF, Orlando EJ, Pruteanu-Malinici I, Gohil M, Lundh S, Boesteanu AC, Wang Y, O'Connor RS, Hwang WT, Pequignot E, Ambrose DE, Zhang C, Wilcox N, Bedoya F, Dorfmeier C, Chen F, Tian L, Parakandi H, Gupta M, Young RM, Johnson FB, Kulikovskaya I, Liu L, Xu J, Kassim SH, Davis MM, Levine BL, Frey NV, Siegel DL, Huang AC, Wherry EJ, Bitter H, Brogdon JL, Porter DL, June CH, Melenhorst JJ

• Frontotemporal lobar degeneration proteinopathies have disparate microscopic patterns of white and grey matter pathology.
  Acta neuropathologica communications. 2021 Feb 23;9(1):30; Authors: Giannini LAA, Peterson C, Ohm D, Xie SX, McMillan CT, Raskovsky K, Massimo L, Suh E, Van Deerlin VM, Wolk DA, Trojanowski JQ, Lee EB, Grossman M, Irwin DJ

• TERRA G-quadruplex RNA interaction with TRF2 GAR domain is required for telomere integrity.
  Scientific reports. 2021 Feb 10;11(1):3509; Authors: Mei Y, Deng Z, Vladimirova O, Gulve N, Johnson FB, Drosopoulos WC, Schildkraut CL, Lieberman PM

• Pathogenic Huntingtin Repeat Expansions in Patients with Frontotemporal Dementia and Amyotrophic Lateral Sclerosis.
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• Evidence-Based Use of Levothyroxine/Liothyronine Combinations in Treating Hypothyroidism: A Consensus Document.
  Thyroid : official journal of the American Thyroid Association. 2021 Feb;31(2):156-182; Authors: Jonklaas J, Bianco AC, Cappola AR, Celi FS, Fliers E, Heuer H, McAninch EA, Moeller LC, Nygaard B, Sawka AM, Watt T, Dayan CM

• Cross-sectional and longitudinal medial temporal lobe subregional atrophy patterns in semantic variant primary progressive aphasia.
  Neurobiology of aging. 2021 Feb;98:231-241 Epub 2020 Nov 23; Authors: Wisse LEM, Ungrady MB, Ittyerah R, Lim SA, Yushkevich PA, Wolk DA, Irwin DJ, Das SR, Grossman M

• Neuropathological consensus criteria for the evaluation of Lewy pathology in post-mortem brains: a multi-centre study.
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• Neuropathology associated with SARS-CoV-2 infection.
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• Early Selective Vulnerability of the CA2 Hippocampal Subfield in Primary Age-Related Tauopathy.
  Journal of neuropathology and experimental neurology. 2021 Jan 20;80(2):102-111; Authors: Walker JM, Richardson TE, Farrell K, Iida MA, Foong C, Shang P, Attems J, Ayalon G, Beach TG, Bigio EH, Budson A, Cairns NJ, Corrada M, Cortes E, Dickson DW, Fischer P, Flanagan ME, Franklin E, Gearing M, Glass J, Hansen LA, Haroutunian V, Hof PR, Honig L, Kawas C, Keene CD, Kofler J, Kovacs GG, Lee EB, Lutz MI, Mao Q, Masliah E, McKee AC, McMillan CT, Mesulam MM, Murray M, Nelson PT, Perrin R, Pham T, Poon W, Purohit DP, Rissman RA, Sakai K, Sano M, Schneider JA, Stein TD, Teich AF, Trojanowski JQ, Troncoso JC, Vonsattel JP, Weintraub S, Wolk DA, Woltjer RL, Yamada M, Yu L, White CL, Crary JF

• Inhibitory signaling sustains a distinct early memory CD8(+) T cell precursor that is resistant to DNA damage.
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• Machine learning suggests polygenic risk for cognitive dysfunction in amyotrophic lateral sclerosis.
  EMBO molecular medicine. 2021 Jan 11;13(1):e12595 Epub 2020 Dec 3; Authors: Placek K, Benatar M, Wuu J, Rampersaud E, Hennessy L, Van Deerlin VM, Grossman M, Irwin DJ, Elman L, McCluskey L, Quinn C, Granit V, Statland JM, Burns TM, Ravits J, Swenson A, Katz J, Pioro EP, Jackson C, Caress J, So Y, Maiser S, Walk D, Lee EB, Trojanowski JQ, Cook P, Gee J, Sha J, Naj AC, Rademakers R, CReATe Consortium, Chen W, Wu G, Paul Taylor J, McMillan CT

• Frontotemporal Lobar Degeneration TDP-43-Immunoreactive Pathological Subtypes: Clinical and Mechanistic Significance.
  Advances in experimental medicine and biology. 2021;1281:201-217; Authors: Neumann M, Lee EB, Mackenzie IR

• Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition)(1).
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• Astroglial tau pathology alone preferentially concentrates at sulcal depths in chronic traumatic encephalopathy neuropathologic change.
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• SLC25A51 is a mammalian mitochondrial NAD(+) transporter.
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• Multimodal in vivo and postmortem assessments of tau in Lewy body disorders.
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• Tau pathology associates with in vivo cortical thinning in Lewy body disorders.
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• Hippocampal subfield pathologic burden in Lewy body diseases vs. Alzheimer's disease.
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• Autosomal dominant VCP hypomorph mutation impairs disaggregation of PHF-tau.
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• An individual participant data analysis of prospective cohort studies on the association between subclinical thyroid dysfunction and depressive symptoms.
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• Distinct clinicopathologic clusters of persons with TDP-43 proteinopathy.
  Acta neuropathologica. 2020 Nov;140(5):659-674 Epub 2020 Aug 14; Authors: Katsumata Y, Abner EL, Karanth S, Teylan MA, Mock CN, Cykowski MD, Lee EB, Boehme KL, Mukherjee S, Kauwe JSK, Kryscio RJ, Schmitt FA, Fardo DW, Nelson PT

• Degeneration of the locus coeruleus is a common feature of tauopathies and distinct from TDP-43 proteinopathies in the frontotemporal lobar degeneration spectrum.
  Acta neuropathologica. 2020 Nov;140(5):675-693 Epub 2020 Aug 17; Authors: Ohm DT, Peterson C, Lobrovich R, Cousins KAQ, Gibbons GS, McMillan CT, Wolk DA, Van Deerlin V, Elman L, Spindler M, Deik A, Siderowf A, Trojanowski JQ, Lee EB, Grossman M, Irwin DJ

• Longitudinal atrophy in early Braak regions in preclinical Alzheimer's disease.
  Human brain mapping. 2020 Nov;41(16):4704-4717 Epub 2020 Aug 26; Authors: Xie L, Wisse LEM, Das SR, Vergnet N, Dong M, Ittyerah R, de Flores R, Yushkevich PA, Wolk DA, Alzheimer's Disease Neuroimaging Initiative

• A quantitative meta-analysis of brain glutamate metabolites in aging.
  Neurobiology of aging. 2020 Nov;95:240-249 Epub 2020 Jul 21; Authors: Roalf DR, Sydnor VJ, Woods M, Wolk DA, Scott JC, Reddy R, Moberg PJ

• Differences in Health Care Utilization, Process of Diabetes Care, Care Satisfaction, and Health Status in Patients With Diabetes in Medicare Advantage Versus Traditional Medicare.
  Medical care. 2020 Nov;58(11):1004-1012; Authors: Park S, Larson EB, Fishman P, White L, Coe NB

• Using Medicare claims in identifying Alzheimer's disease and related dementias.
  Alzheimer's & dementia : the journal of the Alzheimer's Association. 2020 Oct 8; Authors: Jain S, Rosenbaum PR, Reiter JG, Hoffman G, Small DS, Ha J, Hill AS, Wolk DA, Gaulton T, Neuman MD, Eckenhoff RG, Fleisher LA, Silber JH

• APOE and TREM2 regulate amyloid-responsive microglia in Alzheimer's disease.
  Acta neuropathologica. 2020 Oct;140(4):477-493 Epub 2020 Aug 25; Authors: Nguyen AT, Wang K, Hu G, Wang X, Miao Z, Azevedo JA, Suh E, Van Deerlin VM, Choi D, Roeder K, Li M, Lee EB

• ADNC-RS, a clinical-genetic risk score, predicts Alzheimer's pathology in autopsy-confirmed Parkinson's disease and Dementia with Lewy bodies.
  Acta neuropathologica. 2020 Oct;140(4):449-461 Epub 2020 Aug 4; Authors: Dai DL, Tropea TF, Robinson JL, Suh E, Hurtig H, Weintraub D, Van Deerlin V, Lee EB, Trojanowski JQ, Chen-Plotkin AS

• Long-Term Care Policy after Covid-19 - Solving the Nursing Home Crisis.
  The New England journal of medicine. 2020 Sep 3;383(10):903-905 Epub 2020 May 27; Authors: Werner RM, Hoffman AK, Coe NB

• Neural and behavioral correlates of episodic memory are associated with temporal discounting in older adults.
  Neuropsychologia. 2020 Sep;146:107549 Epub 2020 Jul 2; Authors: Lempert KM, Mechanic-Hamilton DJ, Xie L, Wisse LEM, de Flores R, Wang J, Das SR, Yushkevich PA, Wolk DA, Kable JW

• Health Care Costs of Alzheimer's and Related Dementias Within a Medicare Managed Care Provider.
  Medical care. 2020 Sep;58(9):833-841; Authors: Fishman PA, White L, Ingraham B, Park S, Larson EB, Crane P, Coe NB

• Dementia Is Associated With Earlier Mortality for Men and Women in the United States.
  Gerontology & geriatric medicine. 2020 Jan-Dec;6:2333721420945922 Epub 2020 Aug 19; Authors: White L, Fishman P, Basu A, Crane PK, Larson EB, Coe NB

• Primary Care Utilization and Expenditures in Traditional Medicare and Medicare Advantage, 2007-2016.
  Journal of general internal medicine. 2020 Aug;35(8):2480-2481 Epub 2020 May 6; Authors: Park S, Figueroa JF, Fishman P, Coe NB

• Distribution patterns of tau pathology in progressive supranuclear palsy.
  Acta neuropathologica. 2020 Aug;140(2):99-119 Epub 2020 May 7; Authors: Kovacs GG, Lukic MJ, Irwin DJ, Arzberger T, Respondek G, Lee EB, Coughlin D, Giese A, Grossman M, Kurz C, McMillan CT, Gelpi E, Compta Y, van Swieten JC, Laat LD, Troakes C, Al-Sarraj S, Robinson JL, Roeber S, Xie SX, Lee VM, Trojanowski JQ, Höglinger GU

• Informal And Formal Home Care For Older Adults With Disabilities Increased, 2004-16.
  Health affairs (Project Hope). 2020 Aug;39(8):1297-1301; Authors: Van Houtven CH, Konetzka RT, Taggert E, Coe NB

• Defining and predicting transdiagnostic categories of neurodegenerative disease.
  Nature biomedical engineering. 2020 Aug;4(8):787-800 Epub 2020 Aug 3; Authors: Cornblath EJ, Robinson JL, Irwin DJ, Lee EB, Lee VM, Trojanowski JQ, Bassett DS

• Essential Long-Term Care Workers Commonly Hold Second Jobs and Double- or Triple-Duty Caregiving Roles.
  Journal of the American Geriatrics Society. 2020 Aug;68(8):1657-1660 Epub 2020 May 14; Authors: Van Houtven CH, DePasquale N, Coe NB

• Disentangling Heterogeneity in Alzheimer's Disease and Related Dementias Using Data-Driven Methods.
  Biological psychiatry. 2020 Jul 1;88(1):70-82 Epub 2020 Jan 31; Authors: Habes M, Grothe MJ, Tunc B, McMillan C, Wolk DA, Davatzikos C

• Letter to the Editor: "Our Response to COVID-19 as Endocrinologists and Diabetologists".
  The Journal of clinical endocrinology and metabolism. 2020 Jul 1;105(7); Authors: Kobaly K, Mandel SJ, Cappola AR, Kim CS

• Living Arrangements of Older Adults and COVID-19 Risk: It Is Not Just Nursing Homes.
  Journal of the American Geriatrics Society. 2020 Jul;68(7):1398-1399 Epub 2020 May 26; Authors: Coe NB, Van Houtven CH

• MRI signatures of brain age and disease over the lifespan based on a deep brain network and 14 468 individuals worldwide.
  Brain : a journal of neurology. 2020 Jul 1;143(7):2312-2324; Authors: Bashyam VM, Erus G, Doshi J, Habes M, Nasrallah I, Truelove-Hill M, Srinivasan D, Mamourian L, Pomponio R, Fan Y, Launer LJ, Masters CL, Maruff P, Zhuo C, Völzke H, Johnson SC, Fripp J, Koutsouleris N, Satterthwaite TD, Wolf D, Gur RE, Gur RC, Morris J, Albert MS, Grabe HJ, Resnick S, Bryan RN, Wolk DA, Shou H, Davatzikos C

• ATN status in amnestic and non-amnestic Alzheimer's disease and frontotemporal lobar degeneration.
  Brain : a journal of neurology. 2020 Jul 1;143(7):2295-2311; Authors: Cousins KAQ, Irwin DJ, Wolk DA, Lee EB, Shaw LMJ, Trojanowski JQ, Da Re F, Gibbons GS, Grossman M, Phillips JS

• Editorial: Combination Therapy for Hypothyroidism: The Journey From Bench to Bedside.
  Frontiers in endocrinology. 2020;11:422 Epub 2020 Jun 25; Authors: Jonklaas J, Cappola AR, Celi FS

• Continuous Glucose Monitoring in Adolescent, Young Adult, and Older Patients With Type 1 Diabetes.
  JAMA. 2020 Jun 16;323(23):2384-2385; Authors: Agarwal S, Cappola AR

• Coverage Gaps and Cost-Shifting for Work-Related Injury and Illness: Who Bears the Financial Burden?
  Medical care research and review : MCRR. 2020 Jun;77(3):223-235 Epub 2019 Apr 25; Authors: Sears JM, Edmonds AT, Coe NB

• Characterization of hippocampal subfields using ex vivo MRI and histology data: Lessons for in vivo segmentation.
  Hippocampus. 2020 Jun;30(6):545-564 Epub 2019 Nov 1; Authors: de Flores R, Berron D, Ding SL, Ittyerah R, Pluta JB, Xie L, Adler DH, Robinson JL, Schuck T, Trojanowski JQ, Grossman M, Liu W, Pickup S, Das SR, Wolk DA, Yushkevich PA, Wisse LEM

• Contribution of mixed pathology to medial temporal lobe atrophy in Alzheimer's disease.
  Alzheimer's & dementia : the journal of the Alzheimer's Association. 2020 Jun;16(6):843-852 Epub 2020 Apr 22; Authors: de Flores R, Wisse LEM, Das SR, Xie L, McMillan CT, Trojanowski JQ, Robinson JL, Grossman M, Lee E, Irwin DJ, Yushkevich PA, Wolk DA

• Two nights of recovery sleep restores hippocampal connectivity but not episodic memory after total sleep deprivation.
  Scientific reports. 2020 May 29;10(1):8774; Authors: Chai Y, Fang Z, Yang FN, Xu S, Deng Y, Raine A, Wang J, Yu M, Basner M, Goel N, Kim JJ, Wolk DA, Detre JA, Dinges DF, Rao H

• Large-scale proteomic analysis of Alzheimer's disease brain and cerebrospinal fluid reveals early changes in energy metabolism associated with microglia and astrocyte activation.
  Nature medicine. 2020 May;26(5):769-780 Epub 2020 Apr 13; Authors: Johnson ECB, Dammer EB, Duong DM, Ping L, Zhou M, Yin L, Higginbotham LA, Guajardo A, White B, Troncoso JC, Thambisetty M, Montine TJ, Lee EB, Trojanowski JQ, Beach TG, Reiman EM, Haroutunian V, Wang M, Schadt E, Zhang B, Dickson DW, Ertekin-Taner N, Golde TE, Petyuk VA, De Jager PL, Bennett DA, Wingo TS, Rangaraju S, Hajjar I, Shulman JM, Lah JJ, Levey AI, Seyfried NT

• Tau immunophenotypes in chronic traumatic encephalopathy recapitulate those of ageing and Alzheimer's disease.
  Brain : a journal of neurology. 2020 May 1;143(5):1572-1587; Authors: Arena JD, Smith DH, Lee EB, Gibbons GS, Irwin DJ, Robinson JL, Lee VM, Trojanowski JQ, Stewart W, Johnson VE

• Links between autobiographical memory richness and temporal discounting in older adults.
  Scientific reports. 2020 Apr 14;10(1):6431; Authors: Lempert KM, MacNear KA, Wolk DA, Kable JW

• Design of the Optimal Trial of Combination Therapy.
  Frontiers in endocrinology. 2020;11:168 Epub 2020 Apr 3; Authors: Cappola AR

• Washington's privatization of liquor: effects on household alcohol purchases from Initiative 1183.
  Addiction (Abingdon, England). 2020 Apr;115(4):681-689 Epub 2020 Feb 5; Authors: Barnett SBL, Coe NB, Harris JR, Basu A

• Intraoperative cytology of pituicytomas.
  Diagnostic cytopathology. 2020 Apr;48(4):342-349 Epub 2019 Dec 28; Authors: Viaene AN, Lee EB, Nasrallah MP

• RE-AIM Evaluation Plan for Washington State Innovation Models Project.
  Quality management in health care. 2020 Apr/Jun;29(2):81-94; Authors: Grembowski D, Conrad DA, Naranjo D, Wood S, Coe NB, Kwan-Gett T, Baseman J

• Health Care Utilization, Care Satisfaction, and Health Status for Medicare Advantage and Traditional Medicare Beneficiaries With and Without Alzheimer Disease and Related Dementias.
  JAMA network open. 2020 Mar 2;3(3):e201809; Authors: Park S, White L, Fishman P, Larson EB, Coe NB

• Harmonization of large MRI datasets for the analysis of brain imaging patterns throughout the lifespan.
  NeuroImage. 2020 Mar;208:116450 Epub 2019 Dec 9; Authors: Pomponio R, Erus G, Habes M, Doshi J, Srinivasan D, Mamourian E, Bashyam V, Nasrallah IM, Satterthwaite TD, Fan Y, Launer LJ, Masters CL, Maruff P, Zhuo C, Völzke H, Johnson SC, Fripp J, Koutsouleris N, Wolf DH, Gur R, Gur R, Morris J, Albert MS, Grabe HJ, Resnick SM, Bryan RN, Wolk DA, Shinohara RT, Shou H, Davatzikos C

• Estimating regional cerebral blood flow using resting-state functional MRI via machine learning.
  Journal of neuroscience methods. 2020 Feb 1;331:108528 Epub 2019 Nov 19; Authors: Chand GB, Habes M, Dolui S, Detre JA, Wolk DA, Davatzikos C

• G-quadruplexes in fibrotic scars may open new therapeutic avenues for wound healing.
  FEBS letters. 2020 Jan;594(1):19-20 Epub 2019 Dec 18; Authors: Johnson FB, Yatsunyk LA

• Rap1-mediated nucleosome displacement can regulate gene expression in senescent cells without impacting the pace of senescence.
  Aging cell. 2020 Jan;19(1):e13061 Epub 2019 Nov 19; Authors: Song S, Perez JV, Svitko W, Ricketts MD, Dean E, Schultz D, Marmorstein R, Johnson FB

• Disease-Specific Plan Switching Between Traditional Medicare and Medicare Advantage.
  The Permanente journal. 2020;24 Epub 2019 Nov 22; Authors: Park S, Fishman P, White L, Larson EB, Coe NB

• Spending And Quality After Three Years Of Medicare's Voluntary Bundled Payment For Joint Replacement Surgery.
  Health affairs (Project Hope). 2020 Jan;39(1):58-66; Authors: Navathe AS, Emanuel EJ, Venkataramani AS, Huang Q, Gupta A, Dinh CT, Shan EZ, Small D, Coe NB, Wang E, Ma X, Zhu J, Cousins DS, Liao JM

• Arterial spin labeling versus (18)F-FDG-PET to identify mild cognitive impairment.
  NeuroImage. Clinical. 2020;25:102146 Epub 2019 Dec 23; Authors: Dolui S, Li Z, Nasrallah IM, Detre JA, Wolk DA

• Fundamentals of G-quadruplex biology.
  Annual reports in medicinal chemistry. 2020;54:3-44 Epub 2020 Jul 30; Authors: Johnson FB

• Neuronal Transcriptome from C9orf72 Repeat Expanded Human Tissue is Associated with Loss of C9orf72 Function.
  Free neuropathology. 2020;1 Epub 2020 Aug 21; Authors: Liu EY, Russ J, Lee EB

• Targeted DNA methylation of neurodegenerative disease genes via homology directed repair.
  Nucleic acids research. 2019 Dec 16;47(22):11609-11622; Authors: Cali CP, Park DS, Lee EB

• Diffusion Tensor MRI to Distinguish Progressive Supranuclear Palsy from α-Synucleinopathies.
  Radiology. 2019 Dec;293(3):646-653 Epub 2019 Oct 15; Authors: Spotorno N, Hall S, Irwin DJ, Rumetshofer T, Acosta-Cabronero J, Deik AF, Spindler MA, Lee EB, Trojanowski JQ, van Westen D, Nilsson M, Grossman M, Nestor PJ, McMillan CT, Hansson O

• The impact of Medicare copayments for skilled nursing facilities on length of stay, outcomes, and costs.
  Health services research. 2019 Dec;54(6):1184-1192 Epub 2019 Oct 27; Authors: Werner RM, Konetzka RT, Qi M, Coe NB

• The Thyrotropin Reference Range Should Be Changed in Older Patients.
  JAMA. 2019 Nov 26;322(20):1961-1962; Authors: Cappola AR

• C9orf72 intermediate repeats are associated with corticobasal degeneration, increased C9orf72 expression and disruption of autophagy.
  Acta neuropathologica. 2019 Nov;138(5):795-811 Epub 2019 Jul 20; Authors: Cali CP, Patino M, Tai YK, Ho WY, McLean CA, Morris CM, Seeley WW, Miller BL, Gaig C, Vonsattel JPG, White CL 3rd, Roeber S, Kretzschmar H, Troncoso JC, Troakes C, Gearing M, Ghetti B, Van Deerlin VM, Lee VM, Trojanowski JQ, Mok KY, Ling H, Dickson DW, Schellenberg GD, Ling SC, Lee EB

• Genetic predictors of survival in behavioral variant frontotemporal degeneration.
  Neurology. 2019 Oct 29;93(18):e1707-e1714 Epub 2019 Sep 19; Authors: Caswell C, McMillan CT, Xie SX, Van Deerlin VM, Suh E, Lee EB, Trojanowski JQ, Lee VM, Irwin DJ, Grossman M, Massimo LM

• Prediction and Classification of Alzheimer's Disease Based on Combined Features From Apolipoprotein-E Genotype, Cerebrospinal Fluid, MR, and FDG-PET Imaging Biomarkers.
  Frontiers in computational neuroscience. 2019;13:72 Epub 2019 Oct 16; Authors: Gupta Y, Lama RK, Kwon GR, Alzheimer's Disease Neuroimaging Initiative

• Patient Context and Thyrotropin Levels Are Important When Considering Treatment of Subclinical Hypothyroidism.
  Thyroid : official journal of the American Thyroid Association. 2019 Oct;29(10):1359-1363 Epub 2019 Oct 3; Authors: Sawka AM, Cappola AR, Peeters RP, Kopp PA, Bianco AC, Jonklaas J

• In vivo measures of tau burden are associated with atrophy in early Braak stage medial temporal lobe regions in amyloid-negative individuals.
  Alzheimer's & dementia : the journal of the Alzheimer's Association. 2019 Oct;15(10):1286-1295 Epub 2019 Sep 6; Authors: Das SR, Xie L, Wisse LEM, Vergnet N, Ittyerah R, Cui S, Yushkevich PA, Wolk DA, Alzheimer's Disease Neuroimaging Initiative

• Health coaching to improve self-care of informal caregivers of adults with chronic heart failure - iCare4Me: Study protocol for a randomized controlled trial.
  Contemporary clinical trials. 2019 Oct;85:105845 Epub 2019 Sep 6; Authors: Riegel B, Hanlon AL, Coe NB, Hirschman KB, Thomas G, Stawnychy M, Wald JW, Bowles KH

• Association Between High Discharge Rates of Vulnerable Patients and Skilled Nursing Facility Copayments.
  JAMA internal medicine. 2019 Sep 1;179(9):1296-1298; Authors: Chatterjee P, Qi M, Coe NB, Konetzka RT, Werner RM

• Chronic traumatic encephalopathy is a common co-morbidity, but less frequent primary dementia in former soccer and rugby players.
  Acta neuropathologica. 2019 Sep;138(3):389-399 Epub 2019 Jun 1; Authors: Lee EB, Kinch K, Johnson VE, Trojanowski JQ, Smith DH, Stewart W

• New Perspective for Non-invasive Brain Stimulation Site Selection in Mild Cognitive Impairment: Based on Meta- and Functional Connectivity Analyses.
  Frontiers in aging neuroscience. 2019;11:228 Epub 2019 Aug 27; Authors: Liu J, Zhang B, Wilson G, Kong J, Alzheimer’s Disease Neuroimaging Initiative

• Fornix-Region Deep Brain Stimulation-Induced Memory Flashbacks in Alzheimer's Disease.
  The New England journal of medicine. 2019 Aug 22;381(8):783-785; Authors: Deeb W, Salvato B, Almeida L, Foote KD, Amaral R, Germann J, Rosenberg PB, Tang-Wai DF, Wolk DA, Burke AD, Salloway S, Sabbagh MN, Chakravarty MM, Smith GS, Lyketsos CG, Lozano AM, Okun MS

• Thyroid Function Test Abnormalities During Pregnancy.
  JAMA. 2019 Aug 20;322(7):617-619; Authors: Cappola AR, Casey BM

• Automated segmentation of medial temporal lobe subregions on in vivo T1-weighted MRI in early stages of Alzheimer's disease.
  Human brain mapping. 2019 Aug 15;40(12):3431-3451 Epub 2019 Apr 29; Authors: Xie L, Wisse LEM, Pluta J, de Flores R, Piskin V, Manjón JV, Wang H, Das SR, Ding SL, Wolk DA, Yushkevich PA, Alzheimer's Disease Neuroimaging Initiative

• Medicare expenditures attributable to dementia.
  Health services research. 2019 Aug;54(4):773-781 Epub 2019 Mar 13; Authors: White L, Fishman P, Basu A, Crane PK, Larson EB, Coe NB

• A deep learning model for early prediction of Alzheimer's disease dementia based on hippocampal magnetic resonance imaging data.
  Alzheimer's & dementia : the journal of the Alzheimer's Association. 2019 Aug;15(8):1059-1070 Epub 2019 Jun 11; Authors: Li H, Habes M, Wolk DA, Fan Y, Alzheimer's Disease Neuroimaging Initiative and the Australian Imaging Biomarkers and Lifestyle Study of Aging

• Subclinical thyroid dysfunction and depressive symptoms: protocol for a systematic review and individual participant data meta-analysis of prospective cohort studies.
  BMJ open. 2019 Jul 26;9(7):e029716; Authors: Wildisen L, Moutzouri E, Beglinger S, Syrogiannouli L, Cappola AR, Åsvold BO, Bakker SJL, Ceresini G, Dullaart R, Ferrucci L, Grabe H, Jukema JW, Nauck M, Trompet S, Völzke H, Westendorp RGJ, Gussekloo J, Peeters RP, Klöppel S, Aujesky D, Bauer DC, Rodondi N, Del Giovane C, Feller M, Thyroid Studies Collaboration

• Subclinical Hypothyroidism: A Review.
  JAMA. 2019 Jul 9;322(2):153-160; Authors: Biondi B, Cappola AR, Cooper DS

• Empiric Methods to Account for Pre-analytical Variability in Digital Histopathology in Frontotemporal Lobar Degeneration.
  Frontiers in neuroscience. 2019;13:682 Epub 2019 Jul 3; Authors: Giannini LAA, Xie SX, Peterson C, Zhou C, Lee EB, Wolk DA, Grossman M, Trojanowski JQ, McMillan CT, Irwin DJ

• Associative memory for conceptually unitized word pairs in mild cognitive impairment is related to the volume of the perirhinal cortex.
  Hippocampus. 2019 Jul;29(7):630-638 Epub 2018 Dec 26; Authors: Delhaye E, Mechanic-Hamilton D, Saad L, Das SR, Wisse LEM, Yushkevich PA, Wolk DA, Bastin C

• Thyroid and Cardiovascular Disease: Research Agenda for Enhancing Knowledge, Prevention, and Treatment.
  Circulation. 2019 Jun 18;139(25):2892-2909 Epub 2019 May 13; Authors: Cappola AR, Desai AS, Medici M, Cooper LS, Egan D, Sopko G, Fishman GI, Goldman S, Cooper DS, Mora S, Kudenchuk PJ, Hollenberg AN, McDonald CL, Ladenson PW

• Health Insurance and Out-of-Pocket Costs in the Last Year of Life Among Decedents Utilizing the ICU.
  Critical care medicine. 2019 Jun;47(6):749-756; Authors: Khandelwal N, White L, Curtis JR, Coe NB

• Fractionating the Rey Auditory Verbal Learning Test: Distinct roles of large-scale cortical networks in prodromal Alzheimer's disease.
  Neuropsychologia. 2019 Jun;129:83-92 Epub 2019 Mar 28; Authors: Putcha D, Brickhouse M, Wolk DA, Dickerson BC, Alzheimer's Disease Neuroimaging Initiative

• TMEM106B Effect on cognition in Parkinson disease and frontotemporal dementia.
  Annals of neurology. 2019 Jun;85(6):801-811; Authors: Tropea TF, Mak J, Guo MH, Xie SX, Suh E, Rick J, Siderowf A, Weintraub D, Grossman M, Irwin D, Wolk DA, Trojanowski JQ, Van Deerlin V, Chen-Plotkin AS

• Deletion of ULS1 confers damage tolerance in sgs1 mutants through a Top3-dependent D-loop mediated fork restart pathway.
  DNA repair. 2019 Jun;78:102-113 Epub 2019 Apr 13; Authors: Glineburg MR, Johns E, Johnson FB

• Longitudinal progression of grey matter atrophy in non-amnestic Alzheimer's disease.
  Brain : a journal of neurology. 2019 Jun 1;142(6):1701-1722; Authors: Phillips JS, Da Re F, Irwin DJ, McMillan CT, Vaishnavi SN, Xie SX, Lee EB, Cook PA, Gee JC, Shaw LM, Trojanowski JQ, Wolk DA, Grossman M

• Genome-wide analyses as part of the international FTLD-TDP whole-genome sequencing consortium reveals novel disease risk factors and increases support for immune dysfunction in FTLD.
  Acta neuropathologica. 2019 Jun;137(6):879-899 Epub 2019 Feb 9; Authors: Pottier C, Ren Y, Perkerson RB 3rd, Baker M, Jenkins GD, van Blitterswijk M, DeJesus-Hernandez M, van Rooij JGJ, Murray ME, Christopher E, McDonnell SK, Fogarty Z, Batzler A, Tian S, Vicente CT, Matchett B, Karydas AM, Hsiung GR, Seelaar H, Mol MO, Finger EC, Graff C, Öijerstedt L, Neumann M, Heutink P, Synofzik M, Wilke C, Prudlo J, Rizzu P, Simon-Sanchez J, Edbauer D, Roeber S, Diehl-Schmid J, Evers BM, King A, Mesulam MM, Weintraub S, Geula C, Bieniek KF, Petrucelli L, Ahern GL, Reiman EM, Woodruff BK, Caselli RJ, Huey ED, Farlow MR, Grafman J, Mead S, Grinberg LT, Spina S, Grossman M, Irwin DJ, Lee EB, Suh E, Snowden J, Mann D, Ertekin-Taner N, Uitti RJ, Wszolek ZK, Josephs KA, Parisi JE, Knopman DS, Petersen RC, Hodges JR, Piguet O, Geier EG, Yokoyama JS, Rissman RA, Rogaeva E, Keith J, Zinman L, Tartaglia MC, Cairns NJ, Cruchaga C, Ghetti B, Kofler J, Lopez OL, Beach TG, Arzberger T, Herms J, Honig LS, Vonsattel JP, Halliday GM, Kwok JB, White CL 3rd, Gearing M, Glass J, Rollinson S, Pickering-Brown S, Rohrer JD, Trojanowski JQ, Van Deerlin V, Bigio EH, Troakes C, Al-Sarraj S, Asmann Y, Miller BL, Graff-Radford NR, Boeve BF, Seeley WW, Mackenzie IRA, van Swieten JC, Dickson DW, Biernacka JM, Rademakers R

• Thyroid and Cardiovascular Disease: Research Agenda for Enhancing Knowledge, Prevention, and Treatment.
  Thyroid : official journal of the American Thyroid Association. 2019 Jun;29(6):760-777 Epub 2019 May 13; Authors: Cappola AR, Desai AS, Medici M, Cooper LS, Egan D, Sopko G, Fishman GI, Goldman S, Cooper DS, Mora S, Kudenchuk PJ, Hollenberg AN, McDonald CL, Ladenson PW

• Correction to: HnRNPA2 is a novel histone acetyltransferase that mediates mitochondrial stress-induced nuclear gene expression.
  Cell discovery. 2019;5:28 Epub 2019 May 14; Authors: Guha M, Srinivasan S, Guja K, Mejia E, Garcia-Diaz M, Johnson FB, Ruthel G, Kaufman BA, Rappaport EF, Glineburg MR, Fang JK, Klein-Szanto AJ, Nakagawa H, Basha J, Kundu T, Avadhani NG

• Histologic, immunohistochemical, and molecular features of pituicytomas and atypical pituicytomas.
  Acta neuropathologica communications. 2019 May 2;7(1):69; Authors: Viaene AN, Lee EB, Rosenbaum JN, Nasrallah IM, Nasrallah MP

• Divergent patterns of TDP-43 and tau pathologies in primary progressive aphasia.
  Annals of neurology. 2019 May;85(5):630-643 Epub 2019 Mar 28; Authors: Giannini LAA, Xie SX, McMillan CT, Liang M, Williams A, Jester C, Rascovsky K, Wolk DA, Ash S, Lee EB, Trojanowski JQ, Grossman M, Irwin DJ

• Patient Outcomes After Hospital Discharge to Home With Home Health Care vs to a Skilled Nursing Facility.
  JAMA internal medicine. 2019 May 1;179(5):617-623; Authors: Werner RM, Coe NB, Qi M, Konetzka RT

• What is the marginal benefit of payment-induced family care? Impact on Medicaid spending and health of care recipients.
  Health economics. 2019 May;28(5):678-692 Epub 2019 Mar 18; Authors: Coe NB, Guo J, Konetzka RT, Van Houtven CH

• Loss of Nuclear TDP-43 Is Associated with Decondensation of LINE Retrotransposons.
  Cell reports. 2019 Apr 30;27(5):1409-1421.e6; Authors: Liu EY, Russ J, Cali CP, Phan JM, Amlie-Wolf A, Lee EB

• G-quadruplex dynamics contribute to regulation of mitochondrial gene expression.
  Scientific reports. 2019 Apr 3;9(1):5605; Authors: Falabella M, Kolesar JE, Wallace C, de Jesus D, Sun L, Taguchi YV, Wang C, Wang T, Xiang IM, Alder JK, Maheshan R, Horne W, Turek-Herman J, Pagano PJ, St Croix CM, Sondheimer N, Yatsunyk LA, Johnson FB, Kaufman BA

• Response by Cappola and Cappola to Letter Regarding Article, "Thyroid Dysfunction in Heart Failure and Cardiovascular Outcomes".
  Circulation. Heart failure. 2019 Apr;12(4):e006007; Authors: Cappola AR, Cappola TP

• Low thyroid function is not associated with an accelerated deterioration in renal function.
  Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association. 2019 Apr 1;34(4):650-659; Authors: Meuwese CL, van Diepen M, Cappola AR, Sarnak MJ, Shlipak MG, Bauer DC, Fried LP, Iacoviello M, Vaes B, Degryse J, Khaw KT, Luben RN, Åsvold BO, Bjøro T, Vatten LJ, de Craen AJM, Trompet S, Iervasi G, Molinaro S, Ceresini G, Ferrucci L, Dullaart RPF, Bakker SJL, Jukema JW, Kearney PM, Stott DJ, Peeters RP, Franco OH, Völzke H, Walsh JP, Bremner A, Sgarbi JA, Maciel RMB, Imaizumi M, Ohishi W, Dekker FW, Rodondi N, Gussekloo J, den Elzen WPJ, Thyroid Studies Collaboration

• The Cost-Effectiveness of Interventions to Increase Utilization of Prone Positioning for Severe Acute Respiratory Distress Syndrome.
  Critical care medicine. 2019 Mar;47(3):e198-e205; Authors: Baston CM, Coe NB, Guerin C, Mancebo J, Halpern S

• Primum non nocere: a call for balance when reporting on CTE.
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• Histone Acetyltransferase p300 Induces De Novo Super-Enhancers to Drive Cellular Senescence.
  Molecular cell. 2019 Feb 21;73(4):684-698.e8 Epub 2019 Feb 14; Authors: Sen P, Lan Y, Li CY, Sidoli S, Donahue G, Dou Z, Frederick B, Chen Q, Luense LJ, Garcia BA, Dang W, Johnson FB, Adams PD, Schultz DC, Berger SL

• Understanding the evolving phenotype of vascular complications in telomere biology disorders.
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• Elevated YKL-40 and low sAPPβ:YKL-40 ratio in antemortem cerebrospinal fluid of patients with pathologically confirmed FTLD.
  Journal of neurology, neurosurgery, and psychiatry. 2019 Feb;90(2):180-186 Epub 2018 Oct 8; Authors: Alcolea D, Irwin DJ, Illán-Gala I, Muñoz L, Clarimón J, McMillan CT, Fortea J, Blesa R, Lee EB, Trojanowski JQ, Grossman M, Lleó A

• Cognitive and Pathological Influences of Tau Pathology in Lewy Body Disorders.
  Annals of neurology. 2019 Feb;85(2):259-271 Epub 2019 Jan 7; Authors: Coughlin D, Xie SX, Liang M, Williams A, Peterson C, Weintraub D, McMillan CT, Wolk DA, Akhtar RS, Hurtig HI, Branch Coslett H, Hamilton RH, Siderowf AD, Duda JE, Rascovsky K, Lee EB, Lee VM, Grossman M, Trojanowski JQ, Irwin DJ

• Assessment of the Relationship Between Genetic Determinants of Thyroid Function and Atrial Fibrillation: A Mendelian Randomization Study.
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• Association of Biomarker and Physiologic Indices With Mortality in Older Adults: Cardiovascular Health Study.
  The journals of gerontology. Series A, Biological sciences and medical sciences. 2019 Jan 1;74(1):114-120; Authors: Sanders JL, Arnold AM, Boudreau RM, Hirsch CH, Kizer JR, Kaplan RC, Cappola AR, Cushman M, Jacob ME, Kritchevsky SB, Newman AB

• Task-enhanced arterial spin labeled perfusion MRI predicts longitudinal neurodegeneration in mild cognitive impairment.
  Hippocampus. 2019 Jan;29(1):26-36 Epub 2018 Nov 6; Authors: Xie L, Das SR, Pilania A, Daffner M, Stockbower GE, Dolui S, Yushkevich PA, Detre JA, Wolk DA

• Computational assessment of miRNA binding to low and high expression HLA-DPB1 allelic sequences.
  Human immunology. 2019 Jan;80(1):53-61 Epub 2018 Sep 15; Authors: Shieh M, Chitnis N, Clark P, Johnson FB, Kamoun M, Monos D

• Elevated CSF GAP-43 is Alzheimer's disease specific and associated with tau and amyloid pathology.
  Alzheimer's & dementia : the journal of the Alzheimer's Association. 2019 Jan;15(1):55-64 Epub 2018 Oct 12; Authors: Sandelius Å, Portelius E, Källén Å, Zetterberg H, Rot U, Olsson B, Toledo JB, Shaw LM, Lee VMY, Irwin DJ, Grossman M, Weintraub D, Chen-Plotkin A, Wolk DA, McCluskey L, Elman L, Kostanjevecki V, Vandijck M, McBride J, Trojanowski JQ, Blennow K

• UNC13A polymorphism contributes to frontotemporal disease in sporadic amyotrophic lateral sclerosis.
  Neurobiology of aging. 2019 Jan;73:190-199 Epub 2018 Sep 27; Authors: Placek K, Baer GM, Elman L, McCluskey L, Hennessy L, Ferraro PM, Lee EB, Lee VMY, Trojanowski JQ, Van Deerlin VM, Grossman M, Irwin DJ, McMillan CT

• Potential Roles for G-Quadruplexes in Mitochondria.
  Current medicinal chemistry. 2019;26(16):2918-2932; Authors: Falabella M, Fernandez RJ, Johnson FB, Kaufman BA

• Characterizing a perfusion-based periventricular small vessel region of interest.
  NeuroImage. Clinical. 2019;23:101897 Epub 2019 Jun 12; Authors: Dolui S, Tisdall D, Vidorreta M, Jacobs DR Jr, Nasrallah IM, Bryan RN, Wolk DA, Detre JA

• Thyroid Dysfunction in Heart Failure and Cardiovascular Outcomes.
  Circulation. Heart failure. 2018 Dec;11(12):e005266; Authors: Kannan L, Shaw PA, Morley MP, Brandimarto J, Fang JC, Sweitzer NK, Cappola TP, Cappola AR

• Taste Perception and Water Swallow Screen Results in Old-Old Women.
  Geriatrics (Basel, Switzerland). 2018 Nov 20;3(4); Authors: Mulheren RW, Humbert IA, Cappola AR, Fried LP, González-Fernández M

• hnRNPA2 mediated acetylation reduces telomere length in response to mitochondrial dysfunction.
  PloS one. 2018;13(11):e0206897 Epub 2018 Nov 14; Authors: Guha M, Srinivasan S, Johnson FB, Ruthel G, Guja K, Garcia-Diaz M, Kaufman BA, Glineburg MR, Fang J, Nakagawa H, Basha J, Kundu T, Avadhani NG

• Prevalence of amyloid-β pathology in distinct variants of primary progressive aphasia.
  Annals of neurology. 2018 Nov;84(5):729-740; Authors: Bergeron D, Gorno-Tempini ML, Rabinovici GD, Santos-Santos MA, Seeley W, Miller BL, Pijnenburg Y, Keulen MA, Groot C, van Berckel BNM, van der Flier WM, Scheltens P, Rohrer JD, Warren JD, Schott JM, Fox NC, Sanchez-Valle R, Grau-Rivera O, Gelpi E, Seelaar H, Papma JM, van Swieten JC, Hodges JR, Leyton CE, Piguet O, Rogalski EJ, Mesulam MM, Koric L, Kristensen N, Pariente J, Dickerson B, Mackenzie IR, Hsiung GR, Belliard S, Irwin DJ, Wolk DA, Grossman M, Jones M, Harris J, Mann D, Snowden JS, Chrem-Mendez P, Calandri IL, Amengual AA, Miguet-Alfonsi C, Magnin E, Magnani G, Santangelo R, Deramecourt V, Pasquier F, Mattsson N, Nilsson C, Hansson O, Keith J, Masellis M, Black SE, Matías-Guiu JA, Cabrera-Martin MN, Paquet C, Dumurgier J, Teichmann M, Sarazin M, Bottlaender M, Dubois B, Rowe CC, Villemagne VL, Vandenberghe R, Granadillo E, Teng E, Mendez M, Meyer PT, Frings L, Lleó A, Blesa R, Fortea J, Seo SW, Diehl-Schmid J, Grimmer T, Frederiksen KS, Sánchez-Juan P, Chételat G, Jansen W, Bouchard RW, Laforce RJ, Visser PJ, Ossenkoppele R

• Converging Patterns of α-Synuclein Pathology in Multiple System Atrophy.
  Journal of neuropathology and experimental neurology. 2018 Nov 1;77(11):1005-1016; Authors: Brettschneider J, Suh E, Robinson JL, Fang L, Lee EB, Irwin DJ, Grossman M, Van Deerlin VM, Lee VM, Trojanowski JQ

• Patient-derived frontotemporal lobar degeneration brain extracts induce formation and spreading of TDP-43 pathology in vivo.
  Nature communications. 2018 Oct 11;9(1):4220; Authors: Porta S, Xu Y, Restrepo CR, Kwong LK, Zhang B, Brown HJ, Lee EB, Trojanowski JQ, Lee VM

• A Comprehensive Measure of the Costs of Caring for a Parent: Differences According to Functional Status.
  Journal of the American Geriatrics Society. 2018 Oct;66(10):2003-2008 Epub 2018 Sep 17; Authors: Coe NB, Skira MM, Larson EB

• The Relation Between Thyroid Function and Anemia: A Pooled Analysis of Individual Participant Data.
  The Journal of clinical endocrinology and metabolism. 2018 Oct 1;103(10):3658-3667; Authors: Wopereis DM, Du Puy RS, van Heemst D, Walsh JP, Bremner A, Bakker SJL, Bauer DC, Cappola AR, Ceresini G, Degryse J, Dullaart RPF, Feller M, Ferrucci L, Floriani C, Franco OH, Iacoviello M, Iervasi G, Imaizumi M, Jukema JW, Khaw KT, Luben RN, Molinaro S, Nauck M, Patel KV, Peeters RP, Psaty BM, Razvi S, Schindhelm RK, van Schoor NM, Stott DJ, Vaes B, Vanderpump MPJ, Völzke H, Westendorp RGJ, Rodondi N, Cobbaert CM, Gussekloo J, den Elzen WPJ, Thyroid Studies Collaboration

• Non-beta-amyloid/tau cerebrospinal fluid markers inform staging and progression in Alzheimer's disease.
  Alzheimer's research & therapy. 2018 Sep 25;10(1):98; Authors: Gangishetti U, Christina Howell J, Perrin RJ, Louneva N, Watts KD, Kollhoff A, Grossman M, Wolk DA, Shaw LM, Morris JC, Trojanowski JQ, Fagan AM, Arnold SE, Hu WT

• White matter lesions: Spatial heterogeneity, links to risk factors, cognition, genetics, and atrophy.
  Neurology. 2018 Sep 4;91(10):e964-e975 Epub 2018 Aug 3; Authors: Habes M, Sotiras A, Erus G, Toledo JB, Janowitz D, Wolk DA, Shou H, Bryan NR, Doshi J, Völzke H, Schminke U, Hoffmann W, Resnick SM, Grabe HJ, Davatzikos C

• Cerebrospinal fluid neurogranin concentration in neurodegeneration: relation to clinical phenotypes and neuropathology.
  Acta neuropathologica. 2018 Sep;136(3):363-376 Epub 2018 Apr 26; Authors: Portelius E, Olsson B, Höglund K, Cullen NC, Kvartsberg H, Andreasson U, Zetterberg H, Sandelius Å, Shaw LM, Lee VMY, Irwin DJ, Grossman M, Weintraub D, Chen-Plotkin A, Wolk DA, McCluskey L, Elman L, McBride J, Toledo JB, Trojanowski JQ, Blennow K

• Use of Flutemetamol F 18-Labeled Positron Emission Tomography and Other Biomarkers to Assess Risk of Clinical Progression in Patients With Amnestic Mild Cognitive Impairment.
  JAMA neurology. 2018 Sep 1;75(9):1114-1123; Authors: Wolk DA, Sadowsky C, Safirstein B, Rinne JO, Duara R, Perry R, Agronin M, Gamez J, Shi J, Ivanoiu A, Minthon L, Walker Z, Hasselbalch S, Holmes C, Sabbagh M, Albert M, Fleisher A, Loughlin P, Triau E, Frey K, Høgh P, Bozoki A, Bullock R, Salmon E, Farrar G, Buckley CJ, Zanette M, Sherwin PF, Cherubini A, Inglis F

• Clinical aspects of thyroid function during ageing.
  The lancet. Diabetes & endocrinology. 2018 Sep;6(9):733-742 Epub 2018 Jul 17; Authors: Chaker L, Cappola AR, Mooijaart SP, Peeters RP

• Characterizing Anatomical Variability And Alzheimer's Disease Related Cortical Thinning in the Medial Temporal Lobe Using Graph-Based Groupwise Registration And Point Set Geodesic Shooting.
  Shape in medical imaging : International Workshop, ShapeMI 2018, held in conjunction with MICCAI 2018, Granada, Spain, September 20, 2018 : proceedings. ShapeMI (Workshop) (2018 : Granada, Spain). 2018 Sep;11167:28-37 Epub 2018 Nov 23; Authors: Xie L, Wisse LEM, Das SR, Ittyerah R, Wang J, Wolk DA, Yushkevich PA

• Nuclear poly(ADP-ribose) activity is a therapeutic target in amyotrophic lateral sclerosis.
  Acta neuropathologica communications. 2018 Aug 29;6(1):84; Authors: McGurk L, Mojsilovic-Petrovic J, Van Deerlin VM, Shorter J, Kalb RG, Lee VM, Trojanowski JQ, Lee EB, Bonini NM

• Cerebrospinal fluid α-synuclein contributes to the differential diagnosis of Alzheimer's disease.
  Alzheimer's & dementia : the journal of the Alzheimer's Association. 2018 Aug;14(8):1052-1062 Epub 2018 Mar 28; Authors: Shi M, Tang L, Toledo JB, Ginghina C, Wang H, Aro P, Jensen PH, Weintraub D, Chen-Plotkin AS, Irwin DJ, Grossman M, McCluskey L, Elman LB, Wolk DA, Lee EB, Shaw LM, Trojanowski JQ, Zhang J

• Prevalence of the apolipoprotein E ε4 allele in amyloid β positive subjects across the spectrum of Alzheimer's disease.
  Alzheimer's & dementia : the journal of the Alzheimer's Association. 2018 Jul;14(7):913-924 Epub 2018 Mar 28; Authors: Mattsson N, Groot C, Jansen WJ, Landau SM, Villemagne VL, Engelborghs S, Mintun MM, Lleo A, Molinuevo JL, Jagust WJ, Frisoni GB, Ivanoiu A, Chételat G, Resende de Oliveira C, Rodrigue KM, Kornhuber J, Wallin A, Klimkowicz-Mrowiec A, Kandimalla R, Popp J, Aalten PP, Aarsland D, Alcolea D, Almdahl IS, Baldeiras I, van Buchem MA, Cavedo E, Chen K, Cohen AD, Förster S, Fortea J, Frederiksen KS, Freund-Levi Y, Gill KD, Gkatzima O, Grimmer T, Hampel H, Herukka SK, Johannsen P, van Laere K, de Leon MJ, Maier W, Marcusson J, Meulenbroek O, Møllergård HM, Morris JC, Mroczko B, Nordlund A, Prabhakar S, Peters O, Rami L, Rodríguez-Rodríguez E, Roe CM, Rüther E, Santana I, Schröder J, Seo SW, Soininen H, Spiru L, Stomrud E, Struyfs H, Teunissen CE, Verhey FRJ, Vos SJB, van Waalwijk van Doorn LJC, Waldemar G, Wallin ÅK, Wiltfang J, Vandenberghe R, Brooks DJ, Fladby T, Rowe CC, Drzezga A, Verbeek MM, Sarazin M, Wolk DA, Fleisher AS, Klunk WE, Na DL, Sánchez-Juan P, Lee DY, Nordberg A, Tsolaki M, Camus V, Rinne JO, Fagan AM, Zetterberg H, Blennow K, Rabinovici GD, Hansson O, van Berckel BNM, van der Flier WM, Scheltens P, Visser PJ, Ossenkoppele R

• Neurodegenerative disease concomitant proteinopathies are prevalent, age-related and APOE4-associated.
  Brain : a journal of neurology. 2018 Jul 1;141(7):2181-2193; Authors: Robinson JL, Lee EB, Xie SX, Rennert L, Suh E, Bredenberg C, Caswell C, Van Deerlin VM, Yan N, Yousef A, Hurtig HI, Siderowf A, Grossman M, McMillan CT, Miller B, Duda JE, Irwin DJ, Wolk D, Elman L, McCluskey L, Chen-Plotkin A, Weintraub D, Arnold SE, Brettschneider J, Lee VM, Trojanowski JQ

• Publisher Correction: Dysregulation of the epigenetic landscape of normal aging in Alzheimer's disease.
  Nature neuroscience. 2018 Jul;21(7):1018; Authors: Nativio R, Donahue G, Berson A, Lan Y, Amlie-Wolf A, Tuzer F, Toledo JB, Gosai SJ, Gregory BD, Torres C, Trojanowski JQ, Wang LS, Johnson FB, Bonini NM, Berger SL

• Alzheimer's genetic risk is reduced in primary age-related tauopathy: a potential model of resistance?
  Annals of clinical and translational neurology. 2018 Aug;5(8):927-934 Epub 2018 Jun 19; Authors: McMillan CT, Lee EB, Jefferson-George K, Naj A, Van Deerlin VM, Trojanowski JQ, Wolk DA

• Trajectories of IGF-I Predict Mortality in Older Adults: The Cardiovascular Health Study.
  The journals of gerontology. Series A, Biological sciences and medical sciences. 2018 Jun 14;73(7):953-959; Authors: Sanders JL, Guo W, O'Meara ES, Kaplan RC, Pollak MN, Bartz TM, Newman AB, Fried LP, Cappola AR

• Sequential stages and distribution patterns of aging-related tau astrogliopathy (ARTAG) in the human brain.
  Acta neuropathologica communications. 2018 Jun 11;6(1):50; Authors: Kovacs GG, Xie SX, Robinson JL, Lee EB, Smith DH, Schuck T, Lee VM, Trojanowski JQ

• A 2-Step Cerebrospinal Algorithm for the Selection of Frontotemporal Lobar Degeneration Subtypes.
  JAMA neurology. 2018 Jun 1;75(6):738-745; Authors: Lleó A, Irwin DJ, Illán-Gala I, McMillan CT, Wolk DA, Lee EB, Van Deerlin VM, Shaw LM, Trojanowski JQ, Grossman M

• 2SLS versus 2SRI: Appropriate methods for rare outcomes and/or rare exposures.
  Health economics. 2018 Jun;27(6):937-955 Epub 2018 Mar 26; Authors: Basu A, Coe NB, Chapman CG

• An Online Survey of Hypothyroid Patients Demonstrates Prominent Dissatisfaction.
  Thyroid : official journal of the American Thyroid Association. 2018 Jun;28(6):707-721 Epub 2018 Apr 5; Authors: Peterson SJ, Cappola AR, Castro MR, Dayan CM, Farwell AP, Hennessey JV, Kopp PA, Ross DS, Samuels MH, Sawka AM, Taylor PN, Jonklaas J, Bianco AC

• Potential genetic modifiers of disease risk and age at onset in patients with frontotemporal lobar degeneration and GRN mutations: a genome-wide association study.
  The Lancet. Neurology. 2018 Jun;17(6):548-558 Epub 2018 Apr 30; Authors: Pottier C, Zhou X, Perkerson RB 3rd, Baker M, Jenkins GD, Serie DJ, Ghidoni R, Benussi L, Binetti G, López de Munain A, Zulaica M, Moreno F, Le Ber I, Pasquier F, Hannequin D, Sánchez-Valle R, Antonell A, Lladó A, Parsons TM, Finch NA, Finger EC, Lippa CF, Huey ED, Neumann M, Heutink P, Synofzik M, Wilke C, Rissman RA, Slawek J, Sitek E, Johannsen P, Nielsen JE, Ren Y, van Blitterswijk M, DeJesus-Hernandez M, Christopher E, Murray ME, Bieniek KF, Evers BM, Ferrari C, Rollinson S, Richardson A, Scarpini E, Fumagalli GG, Padovani A, Hardy J, Momeni P, Ferrari R, Frangipane F, Maletta R, Anfossi M, Gallo M, Petrucelli L, Suh E, Lopez OL, Wong TH, van Rooij JGJ, Seelaar H, Mead S, Caselli RJ, Reiman EM, Noel Sabbagh M, Kjolby M, Nykjaer A, Karydas AM, Boxer AL, Grinberg LT, Grafman J, Spina S, Oblak A, Mesulam MM, Weintraub S, Geula C, Hodges JR, Piguet O, Brooks WS, Irwin DJ, Trojanowski JQ, Lee EB, Josephs KA, Parisi JE, Ertekin-Taner N, Knopman DS, Nacmias B, Piaceri I, Bagnoli S, Sorbi S, Gearing M, Glass J, Beach TG, Black SE, Masellis M, Rogaeva E, Vonsattel JP, Honig LS, Kofler J, Bruni AC, Snowden J, Mann D, Pickering-Brown S, Diehl-Schmid J, Winkelmann J, Galimberti D, Graff C, Öijerstedt L, Troakes C, Al-Sarraj S, Cruchaga C, Cairns NJ, Rohrer JD, Halliday GM, Kwok JB, van Swieten JC, White CL 3rd, Ghetti B, Murell JR, Mackenzie IRA, Hsiung GR, Borroni B, Rossi G, Tagliavini F, Wszolek ZK, Petersen RC, Bigio EH, Grossman M, Van Deerlin VM, Seeley WW, Miller BL, Graff-Radford NR, Boeve BF, Dickson DW, Biernacka JM, Rademakers R

• Longitudinal and cross-sectional structural magnetic resonance imaging correlates of AV-1451 uptake.
  Neurobiology of aging. 2018 Jun;66:49-58 Epub 2018 Feb 9; Authors: Das SR, Xie L, Wisse LEM, Ittyerah R, Tustison NJ, Dickerson BC, Yushkevich PA, Wolk DA, Alzheimer's Disease Neuroimaging Initiative

• Diagnostic Accuracy of Ultrasound With Color Flow Doppler in Children With Thyroid Nodules.
  The Journal of clinical endocrinology and metabolism. 2018 May 1;103(5):1958-1965; Authors: Gannon AW, Langer JE, Bellah R, Ratcliffe S, Pizza J, Mostoufi-Moab S, Cappola AR, Bauer AJ

• Determinants of response and resistance to CD19 chimeric antigen receptor (CAR) T cell therapy of chronic lymphocytic leukemia.
  Nature medicine. 2018 May;24(5):563-571 Epub 2018 Apr 30; Authors: Fraietta JA, Lacey SF, Orlando EJ, Pruteanu-Malinici I, Gohil M, Lundh S, Boesteanu AC, Wang Y, O'Connor RS, Hwang WT, Pequignot E, Ambrose DE, Zhang C, Wilcox N, Bedoya F, Dorfmeier C, Chen F, Tian L, Parakandi H, Gupta M, Young RM, Johnson FB, Kulikovskaya I, Liu L, Xu J, Kassim SH, Davis MM, Levine BL, Frey NV, Siegel DL, Huang AC, Wherry EJ, Bitter H, Brogdon JL, Porter DL, June CH, Melenhorst JJ

• Characterizing the human hippocampus in aging and Alzheimer's disease using a computational atlas derived from ex vivo MRI and histology.
  Proceedings of the National Academy of Sciences of the United States of America. 2018 Apr 17;115(16):4252-4257 Epub 2018 Mar 28; Authors: Adler DH, Wisse LEM, Ittyerah R, Pluta JB, Ding SL, Xie L, Wang J, Kadivar S, Robinson JL, Schuck T, Trojanowski JQ, Grossman M, Detre JA, Elliott MA, Toledo JB, Liu W, Pickup S, Miller MI, Das SR, Wolk DA, Yushkevich PA

• TERRA and the histone methyltransferase Dot1 cooperate to regulate senescence in budding yeast.
  PloS one. 2018;13(4):e0195698 Epub 2018 Apr 12; Authors: Wanat JJ, Logsdon GA, Driskill JH, Deng Z, Lieberman PM, Johnson FB

• Epigenetic Mechanisms Impacting Aging: A Focus on Histone Levels and Telomeres.
  Genes. 2018 Apr 9;9(4); Authors: Song S, Johnson FB

• 18F-florbetapir Positron Emission Tomography-determined Cerebral β-Amyloid Deposition and Neurocognitive Performance after Cardiac Surgery.
  Anesthesiology. 2018 Apr;128(4):728-744; Authors: Klinger RY, James OG, Borges-Neto S, Bisanar T, Li YJ, Qi W, Berger M, Terrando N, Newman MF, Doraiswamy PM, Mathew JP, Alzheimer’s Disease Neuroimaging Initiative (ADNI) Study Group, Neurologic Outcomes Research Group (NORG)

• Integrated neurodegenerative disease autopsy diagnosis.
  Acta neuropathologica. 2018 Apr;135(4):643-646 Epub 2018 Mar 3; Authors: Lee EB

• Dysregulation of the epigenetic landscape of normal aging in Alzheimer's disease.
  Nature neuroscience. 2018 Apr;21(4):497-505 Epub 2018 Mar 5; Authors: Nativio R, Donahue G, Berson A, Lan Y, Amlie-Wolf A, Tuzer F, Toledo JB, Gosai SJ, Gregory BD, Torres C, Trojanowski JQ, Wang LS, Johnson FB, Bonini NM, Berger SL

• The National Institute on Aging and the Alzheimer's Association Research Framework for Alzheimer's disease: Perspectives from the Research Roundtable.
  Alzheimer's & dementia : the journal of the Alzheimer's Association. 2018 Apr;14(4):563-575; Authors: Knopman DS, Haeberlein SB, Carrillo MC, Hendrix JA, Kerchner G, Margolin R, Maruff P, Miller DS, Tong G, Tome MB, Murray ME, Nelson PT, Sano M, Mattsson N, Sultzer DL, Montine TJ, Jack CR Jr, Kolb H, Petersen RC, Vemuri P, Canniere MZ, Schneider JA, Resnick SM, Romano G, van Harten AC, Wolk DA, Bain LJ, Siemers E

• A regulatory loop connecting WNT signaling and telomere capping: possible therapeutic implications for dyskeratosis congenita.
  Annals of the New York Academy of Sciences. 2018 Apr;1418(1):56-68; Authors: Fernandez RJ 3rd, Johnson FB

• Genome-wide Analyses Identify KIF5A as a Novel ALS Gene.
  Neuron. 2018 Mar 21;97(6):1267-1288; Authors: Nicolas A, Kenna KP, Renton AE, Ticozzi N, Faghri F, Chia R, Dominov JA, Kenna BJ, Nalls MA, Keagle P, Rivera AM, van Rheenen W, Murphy NA, van Vugt JJFA, Geiger JT, Van der Spek RA, Pliner HA, Shankaracharya, Smith BN, Marangi G, Topp SD, Abramzon Y, Gkazi AS, Eicher JD, Kenna A, ITALSGEN Consortium, Mora G, Calvo A, Mazzini L, Riva N, Mandrioli J, Caponnetto C, Battistini S, Volanti P, La Bella V, Conforti FL, Borghero G, Messina S, Simone IL, Trojsi F, Salvi F, Logullo FO, D'Alfonso S, Corrado L, Capasso M, Ferrucci L, Genomic Translation for ALS Care (GTAC) Consortium, Moreno CAM, Kamalakaran S, Goldstein DB, ALS Sequencing Consortium, Gitler AD, Harris T, Myers RM, NYGC ALS Consortium, Phatnani H, Musunuri RL, Evani US, Abhyankar A, Zody MC, Answer ALS Foundation, Kaye J, Finkbeiner S, Wyman SK, LeNail A, Lima L, Fraenkel E, Svendsen CN, Thompson LM, Van Eyk JE, Berry JD, Miller TM, Kolb SJ, Cudkowicz M, Baxi E, Clinical Research in ALS and Related Disorders for Therapeutic Development (CReATe) Consortium, Benatar M, Taylor JP, Rampersaud E, Wu G, Wuu J, SLAGEN Consortium, Lauria G, Verde F, Fogh I, Tiloca C, Comi GP, Sorarù G, Cereda C, French ALS Consortium, Corcia P, Laaksovirta H, Myllykangas L, Jansson L, Valori M, Ealing J, Hamdalla H, Rollinson S, Pickering-Brown S, Orrell RW, Sidle KC, Malaspina A, Hardy J, Singleton AB, Johnson JO, Arepalli S, Sapp PC, McKenna-Yasek D, Polak M, Asress S, Al-Sarraj S, King A, Troakes C, Vance C, de Belleroche J, Baas F, Ten Asbroek ALMA, Muñoz-Blanco JL, Hernandez DG, Ding J, Gibbs JR, Scholz SW, Floeter MK, Campbell RH, Landi F, Bowser R, Pulst SM, Ravits JM, MacGowan DJL, Kirby J, Pioro EP, Pamphlett R, Broach J, Gerhard G, Dunckley TL, Brady CB, Kowall NW, Troncoso JC, Le Ber I, Mouzat K, Lumbroso S, Heiman-Patterson TD, Kamel F, Van Den Bosch L, Baloh RH, Strom TM, Meitinger T, Shatunov A, Van Eijk KR, de Carvalho M, Kooyman M, Middelkoop B, Moisse M, McLaughlin RL, Van Es MA, Weber M, Boylan KB, Van Blitterswijk M, Rademakers R, Morrison KE, Basak AN, Mora JS, Drory VE, Shaw PJ, Turner MR, Talbot K, Hardiman O, Williams KL, Fifita JA, Nicholson GA, Blair IP, Rouleau GA, Esteban-Pérez J, García-Redondo A, Al-Chalabi A, Project MinE ALS Sequencing Consortium, Rogaeva E, Zinman L, Ostrow LW, Maragakis NJ, Rothstein JD, Simmons Z, Cooper-Knock J, Brice A, Goutman SA, Feldman EL, Gibson SB, Taroni F, Ratti A, Gellera C, Van Damme P, Robberecht W, Fratta P, Sabatelli M, Lunetta C, Ludolph AC, Andersen PM, Weishaupt JH, Camu W, Trojanowski JQ, Van Deerlin VM, Brown RH Jr, van den Berg LH, Veldink JH, Harms MB, Glass JD, Stone DJ, Tienari P, Silani V, Chiò A, Shaw CE, Traynor BJ, Landers JE

• CSF tau and β-amyloid predict cerebral synucleinopathy in autopsied Lewy body disorders.
  Neurology. 2018 Mar 20;90(12):e1038-e1046 Epub 2018 Feb 21; Authors: Irwin DJ, Xie SX, Coughlin D, Nevler N, Akhtar RS, McMillan CT, Lee EB, Wolk DA, Weintraub D, Chen-Plotkin A, Duda JE, Spindler M, Siderowf A, Hurtig HI, Shaw LM, Grossman M, Trojanowski JQ

• The personalized Alzheimer's disease cortical thickness index predicts likely pathology and clinical progression in mild cognitive impairment.
  Alzheimer's & dementia (Amsterdam, Netherlands). 2018;10:301-310 Epub 2018 Mar 17; Authors: Racine AM, Brickhouse M, Wolk DA, Dickerson BC, Alzheimer's Disease Neuroimaging Initiative

• The technical reliability and biotemporal stability of cerebrospinal fluid biomarkers for profiling multiple pathophysiologies in Alzheimer's disease.
  PloS one. 2018;13(3):e0193707 Epub 2018 Mar 5; Authors: Trombetta BA, Carlyle BC, Koenig AM, Shaw LM, Trojanowski JQ, Wolk DA, Locascio JJ, Arnold SE

• Regional tract-specific white matter hyperintensities are associated with patterns to aging-related brain atrophy via vascular risk factors, but also independently.
  Alzheimer's & dementia (Amsterdam, Netherlands). 2018;10:278-284 Epub 2018 Mar 5; Authors: Habes M, Erus G, Toledo JB, Bryan N, Janowitz D, Doshi J, Völzke H, Schminke U, Hoffmann W, Grabe HJ, Wolk DA, Davatzikos C

• Tauopathy with hippocampal 4-repeat tau immunoreactive spherical inclusions: a report of three cases.
  Brain pathology (Zurich, Switzerland). 2018 Mar;28(2):274-283 Epub 2017 Jan 19; Authors: Kovacs GG, Kwong LK, Grossman M, Irwin DJ, Lee EB, Robinson JL, Suh E, Van Deerlin VM, Lee VM, Trojanowski JQ

• Neocortical origin and progression of gray matter atrophy in nonamnestic Alzheimer's disease.
  Neurobiology of aging. 2018 Mar;63:75-87 Epub 2017 Nov 21; Authors: Phillips JS, Da Re F, Dratch L, Xie SX, Irwin DJ, McMillan CT, Vaishnavi SN, Ferrarese C, Lee EB, Shaw LM, Trojanowski JQ, Wolk DA, Grossman M

• Novel and Haplotype Specific MicroRNAs Encoded by the Major Histocompatibility Complex.
  Scientific reports. 2018 Mar 1;8(1):3832; Authors: Clark PM, Chitnis N, Shieh M, Kamoun M, Johnson FB, Monos D

• Defining SNAP by cross-sectional and longitudinal definitions of neurodegeneration.
  NeuroImage. Clinical. 2018;18:407-412 Epub 2018 Feb 8; Authors: Wisse LEM, Das SR, Davatzikos C, Dickerson BC, Xie SX, Yushkevich PA, Wolk DA, Alzheimer's Disease Neuroimaging Initiative

• Tau PET imaging predicts cognition in atypical variants of Alzheimer's disease.
  Human brain mapping. 2018 Feb;39(2):691-708 Epub 2017 Nov 6; Authors: Phillips JS, Das SR, McMillan CT, Irwin DJ, Roll EE, Da Re F, Nasrallah IM, Wolk DA, Grossman M

• (18)F-Flortaucipir PET/MRI Correlations in Nonamnestic and Amnestic Variants of Alzheimer Disease.
  Journal of nuclear medicine : official publication, Society of Nuclear Medicine. 2018 Feb;59(2):299-306 Epub 2017 Jul 26; Authors: Nasrallah IM, Chen YJ, Hsieh MK, Phillips JS, Ternes K, Stockbower GE, Sheline Y, McMillan CT, Grossman M, Wolk DA

• Mapping the structural and functional network architecture of the medial temporal lobe using 7T MRI.
  Human brain mapping. 2018 Feb;39(2):851-865 Epub 2017 Nov 20; Authors: Shah P, Bassett DS, Wisse LEM, Detre JA, Stein JM, Yushkevich PA, Shinohara RT, Pluta JB, Valenciano E, Daffner M, Wolk DA, Elliott MA, Litt B, Davis KA, Das SR

• Association of Cerebral Amyloid-β Aggregation With Cognitive Functioning in Persons Without Dementia.
  JAMA psychiatry. 2018 Jan 1;75(1):84-95; Authors: Jansen WJ, Ossenkoppele R, Tijms BM, Fagan AM, Hansson O, Klunk WE, van der Flier WM, Villemagne VL, Frisoni GB, Fleisher AS, Lleó A, Mintun MA, Wallin A, Engelborghs S, Na DL, Chételat G, Molinuevo JL, Landau SM, Mattsson N, Kornhuber J, Sabri O, Rowe CC, Parnetti L, Popp J, Fladby T, Jagust WJ, Aalten P, Lee DY, Vandenberghe R, Resende de Oliveira C, Kapaki E, Froelich L, Ivanoiu A, Gabryelewicz T, Verbeek MM, Sanchez-Juan P, Hildebrandt H, Camus V, Zboch M, Brooks DJ, Drzezga A, Rinne JO, Newberg A, de Mendonça A, Sarazin M, Rabinovici GD, Madsen K, Kramberger MG, Nordberg A, Mok V, Mroczko B, Wolk DA, Meyer PT, Tsolaki M, Scheltens P, Verhey FRJ, Visser PJ, Amyloid Biomarker Study Group, Aarsland D, Alcolea D, Alexander M, Almdahl IS, Arnold SE, Baldeiras I, Barthel H, van Berckel BNM, Blennow K, van Buchem MA, Cavedo E, Chen K, Chipi E, Cohen AD, Förster S, Fortea J, Frederiksen KS, Freund-Levi Y, Gkatzima O, Gordon MF, Grimmer T, Hampel H, Hausner L, Hellwig S, Herukka SK, Johannsen P, Klimkowicz-Mrowiec A, Köhler S, Koglin N, van Laere K, de Leon M, Lisetti V, Maier W, Marcusson J, Meulenbroek O, Møllergård HM, Morris JC, Nordlund A, Novak GP, Paraskevas GP, Perera G, Peters O, Ramakers IHGB, Rami L, Rodríguez-Rodríguez E, Roe CM, Rot U, Rüther E, Santana I, Schröder J, Seo SW, Soininen H, Spiru L, Stomrud E, Struyfs H, Teunissen CE, Vos SJB, van Waalwijk van Doorn LJC, Waldemar G, Wallin ÅK, Wiltfang J, Zetterberg H

• Asymmetry of post-mortem neuropathology in behavioural-variant frontotemporal dementia.
  Brain : a journal of neurology. 2018 Jan 1;141(1):288-301; Authors: Irwin DJ, McMillan CT, Xie SX, Rascovsky K, Van Deerlin VM, Coslett HB, Hamilton R, Aguirre GK, Lee EB, Lee VMY, Trojanowski JQ, Grossman M

• Association between subclinical thyroid dysfunction and change in bone mineral density in prospective cohorts.
  Journal of internal medicine. 2018 Jan;283(1):56-72 Epub 2017 Oct 16; Authors: Segna D, Bauer DC, Feller M, Schneider C, Fink HA, Aubert CE, Collet TH, da Costa BR, Fischer K, Peeters RP, Cappola AR, Blum MR, van Dorland HA, Robbins J, Naylor K, Eastell R, Uitterlinden AG, Rivadeneira Ramirez F, Gogakos A, Gussekloo J, Williams GR, Schwartz A, Cauley JA, Aujesky DA, Bischoff-Ferrari HA, Rodondi N, Thyroid Studies Collaboration

• Early Tau Burden Correlates with Higher Rate of Atrophy in Transentorhinal Cortex.
  Journal of Alzheimer's disease : JAD. 2018;62(1):85-92; Authors: Xie L, Das SR, Wisse LEM, Ittyerah R, Yushkevich PA, Wolk DA, Alzheimer’s Disease Neuroimaging Initiative

• Automated Multi-Atlas Segmentation of Hippocampal and Extrahippocampal Subregions in Alzheimer's Disease at 3T and 7T: What Atlas Composition Works Best?
  Journal of Alzheimer's disease : JAD. 2018;63(1):217-225; Authors: Xie L, Shinohara RT, Ittyerah R, Kuijf HJ, Pluta JB, Blom K, Kooistra M, Reijmer YD, Koek HL, Zwanenburg JJM, Wang H, Luijten PR, Geerlings MI, Das SR, Biessels GJ, Wolk DA, Yushkevich PA, Wisse LEM

• Disease Course Varies According to Age and Symptom Length in Alzheimer's Disease.
  Journal of Alzheimer's disease : JAD. 2018;64(2):631-642; Authors: Barnes J, Bartlett JW, Wolk DA, van der Flier WM, Frost C

• Assessing robustness of hazard ratio estimates to outcome misclassification in longitudinal panel studies with application to Alzheimer's disease.
  PloS one. 2017;12(12):e0190107 Epub 2017 Dec 22; Authors: Wang L, Hubbard RA, Walker RL, Lee EB, Larson EB, Crane PK

• TDP-43 Promotes Neurodegeneration by Impairing Chromatin Remodeling.
  Current biology : CB. 2017 Dec 4;27(23):3579-3590.e6 Epub 2017 Nov 16; Authors: Berson A, Sartoris A, Nativio R, Van Deerlin V, Toledo JB, Porta S, Liu S, Chung CY, Garcia BA, Lee VM, Trojanowski JQ, Johnson FB, Berger SL, Bonini NM

• Approach to atypical Alzheimer's disease and case studies of the major subtypes.
  CNS spectrums. 2017 Dec;22(6):439-449 Epub 2017 Feb 15; Authors: Dickerson BC, McGinnis SM, Xia C, Price BH, Atri A, Murray ME, Mendez MF, Wolk DA

• Evaluating the Economic Impact of Palliative and End-of-Life Care Interventions on Intensive Care Unit Utilization and Costs from the Hospital and Healthcare System Perspective.
  Journal of palliative medicine. 2017 Dec;20(12):1314-1320 Epub 2017 Oct 3; Authors: Khandelwal N, Brumback LC, Halpern SD, Coe NB, Brumback B, Curtis JR

• Thyroid Function Within the Normal Range, Subclinical Hypothyroidism, and the Risk of Atrial Fibrillation.
  Circulation. 2017 Nov 28;136(22):2100-2116 Epub 2017 Oct 23; Authors: Baumgartner C, da Costa BR, Collet TH, Feller M, Floriani C, Bauer DC, Cappola AR, Heckbert SR, Ceresini G, Gussekloo J, den Elzen WPJ, Peeters RP, Luben R, Völzke H, Dörr M, Walsh JP, Bremner A, Iacoviello M, Macfarlane P, Heeringa J, Stott DJ, Westendorp RGJ, Khaw KT, Magnani JW, Aujesky D, Rodondi N, Thyroid Studies Collaboration

• Circulating brain-enriched microRNAs as novel biomarkers for detection and differentiation of neurodegenerative diseases.
  Alzheimer's research & therapy. 2017 Nov 9;9(1):89; Authors: Sheinerman KS, Toledo JB, Tsivinsky VG, Irwin D, Grossman M, Weintraub D, Hurtig HI, Chen-Plotkin A, Wolk DA, McCluskey LF, Elman LB, Trojanowski JQ, Umansky SR

• Comparison of In Vivo and Ex Vivo MRI of the Human Hippocampal Formation in the Same Subjects.
  Cerebral cortex (New York, N.Y. : 1991). 2017 Nov 1;27(11):5185-5196; Authors: Wisse LEM, Adler DH, Ittyerah R, Pluta JB, Robinson JL, Schuck T, Trojanowski JQ, Grossman M, Detre JA, Elliott MA, Toledo JB, Liu W, Pickup S, Das SR, Wolk DA, Yushkevich PA

• Single Stem Cell Imaging and Analysis Reveals Telomere Length Differences in Diseased Human and Mouse Skeletal Muscles.
  Stem cell reports. 2017 Oct 10;9(4):1328-1341 Epub 2017 Sep 7; Authors: Tichy ED, Sidibe DK, Tierney MT, Stec MJ, Sharifi-Sanjani M, Hosalkar H, Mubarak S, Johnson FB, Sacco A, Mourkioti F

• Comparison of PASL, PCASL, and background-suppressed 3D PCASL in mild cognitive impairment.
  Human brain mapping. 2017 Oct;38(10):5260-5273 Epub 2017 Jul 24; Authors: Dolui S, Vidorreta M, Wang Z, Nasrallah IM, Alavi A, Wolk DA, Detre JA

• Neuron loss and degeneration in the progression of TDP-43 in frontotemporal lobar degeneration.
  Acta neuropathologica communications. 2017 Sep 6;5(1):68; Authors: Yousef A, Robinson JL, Irwin DJ, Byrne MD, Kwong LK, Lee EB, Xu Y, Xie SX, Rennert L, Suh E, Van Deerlin VM, Grossman M, Lee VM, Trojanowski JQ

• Cognitive decline associated with pathological burden in primary age-related tauopathy.
  Alzheimer's & dementia : the journal of the Alzheimer's Association. 2017 Sep;13(9):1048-1053 Epub 2017 Mar 16; Authors: Jefferson-George KS, Wolk DA, Lee EB, McMillan CT

• Effects of cognitive reserve depend on executive and semantic demands of the task.
  Journal of neurology, neurosurgery, and psychiatry. 2017 Sep;88(9):794-802 Epub 2017 Jun 19; Authors: Darby RR, Brickhouse M, Wolk DA, Dickerson BC, Alzheimer’s Disease Neuroimaging Initiative

• Whole-brain background-suppressed pCASL MRI with 1D-accelerated 3D RARE Stack-Of-Spirals readout.
  PloS one. 2017;12(8):e0183762 Epub 2017 Aug 24; Authors: Vidorreta M, Wang Z, Chang YV, Wolk DA, Fernández-Seara MA, Detre JA

• Defining Optimal Health Range for Thyroid Function Based on the Risk of Cardiovascular Disease.
  The Journal of clinical endocrinology and metabolism. 2017 Aug 1;102(8):2853-2861; Authors: Chaker L, Korevaar TIM, Rizopoulos D, Collet TH, Völzke H, Hofman A, Rodondi N, Cappola AR, Peeters RP, Franco OH

• Modeling Esophagitis Using Human Three-Dimensional Organotypic Culture System.
  The American journal of pathology. 2017 Aug;187(8):1787-1799 Epub 2017 Jun 13; Authors: Laczkó D, Wang F, Johnson FB, Jhala N, Rosztóczy A, Ginsberg GG, Falk GW, Rustgi AK, Lynch JP

• Ante mortem cerebrospinal fluid tau levels correlate with postmortem tau pathology in frontotemporal lobar degeneration.
  Annals of neurology. 2017 Aug;82(2):247-258 Epub 2017 Aug 19; Authors: Irwin DJ, Lleó A, Xie SX, McMillan CT, Wolk DA, Lee EB, Van Deerlin VM, Shaw LM, Trojanowski JQ, Grossman M

• Bridging cognitive screening tests in neurologic disorders: A crosswalk between the short Montreal Cognitive Assessment and Mini-Mental State Examination.
  Alzheimer's & dementia : the journal of the Alzheimer's Association. 2017 Aug;13(8):947-952 Epub 2017 Feb 24; Authors: Roalf DR, Moore TM, Mechanic-Hamilton D, Wolk DA, Arnold SE, Weintraub DA, Moberg PJ

• Thyroid Function Tests in the Reference Range and Fracture: Individual Participant Analysis of Prospective Cohorts.
  The Journal of clinical endocrinology and metabolism. 2017 Aug 1;102(8):2719-2728; Authors: Aubert CE, Floriani C, Bauer DC, da Costa BR, Segna D, Blum MR, Collet TH, Fink HA, Cappola AR, Syrogiannouli L, Peeters RP, Åsvold BO, den Elzen WPJ, Luben RN, Bremner AP, Gogakos A, Eastell R, Kearney PM, Hoff M, Le Blanc E, Ceresini G, Rivadeneira F, Uitterlinden AG, Khaw KT, Langhammer A, Stott DJ, Westendorp RGJ, Ferrucci L, Williams GR, Gussekloo J, Walsh JP, Aujesky D, Rodondi N, Thyroid Studies Collaboration

• TDP-43 Depletion in Microglia Promotes Amyloid Clearance but Also Induces Synapse Loss.
  Neuron. 2017 Jul 19;95(2):297-308.e6 Epub 2017 Jun 29; Authors: Paolicelli RC, Jawaid A, Henstridge CM, Valeri A, Merlini M, Robinson JL, Lee EB, Rose J, Appel S, Lee VM, Trojanowski JQ, Spires-Jones T, Schulz PE, Rajendran L

• Multisite Assessment of Aging-Related Tau Astrogliopathy (ARTAG).
  Journal of neuropathology and experimental neurology. 2017 Jul 1;76(7):605-619; Authors: Kovacs GG, Xie SX, Lee EB, Robinson JL, Caswell C, Irwin DJ, Toledo JB, Johnson VE, Smith DH, Alafuzoff I, Attems J, Bencze J, Bieniek KF, Bigio EH, Bodi I, Budka H, Dickson DW, Dugger BN, Duyckaerts C, Ferrer I, Forrest SL, Gelpi E, Gentleman SM, Giaccone G, Grinberg LT, Halliday GM, Hatanpaa KJ, Hof PR, Hofer M, Hortobágyi T, Ironside JW, King A, Kofler J, Kövari E, Kril JJ, Love S, Mackenzie IR, Mao Q, Matej R, McLean C, Munoz DG, Murray ME, Neltner J, Nelson PT, Ritchie D, Rodriguez RD, Rohan Z, Rozemuller A, Sakai K, Schultz C, Seilhean D, Smith V, Tacik P, Takahashi H, Takao M, Rudolf Thal D, Weis S, Wharton SB, White CL 3rd, Woulfe JM, Yamada M, Trojanowski JQ

• Expansion of the classification of FTLD-TDP: distinct pathology associated with rapidly progressive frontotemporal degeneration.
  Acta neuropathologica. 2017 Jul;134(1):65-78 Epub 2017 Jan 27; Authors: Lee EB, Porta S, Michael Baer G, Xu Y, Suh E, Kwong LK, Elman L, Grossman M, Lee VM, Irwin DJ, Van Deerlin VM, Trojanowski JQ

• Clinical marker for Alzheimer disease pathology in logopenic primary progressive aphasia.
  Neurology. 2017 Jun 13;88(24):2276-2284 Epub 2017 May 17; Authors: Giannini LAA, Irwin DJ, McMillan CT, Ash S, Rascovsky K, Wolk DA, Van Deerlin VM, Lee EB, Trojanowski JQ, Grossman M

• Detection of G-quadruplex DNA in mammalian cells.
  Nucleic acids research. 2017 Jun 2;45(10):6252; Authors: Henderson A, Wu Y, Huang YC, Chavez EA, Platt J, Johnson FB, Brosh RM Jr, Sen D, Lansdorp PM

• Structural Correlation-based Outlier Rejection (SCORE) algorithm for arterial spin labeling time series.
  Journal of magnetic resonance imaging : JMRI. 2017 Jun;45(6):1786-1797 Epub 2016 Aug 29; Authors: Dolui S, Wang Z, Shinohara RT, Wolk DA, Detre JA, Alzheimer's Disease Neuroimaging Initiative

• Progression of alpha-synuclein pathology in multiple system atrophy of the cerebellar type.
  Neuropathology and applied neurobiology. 2017 Jun;43(4):315-329 Epub 2016 Oct 18; Authors: Brettschneider J, Irwin DJ, Boluda S, Byrne MD, Fang L, Lee EB, Robinson JL, Suh E, Van Deerlin VM, Toledo JB, Grossman M, Hurtig H, Dengler R, Petri S, Lee VM, Trojanowski JQ

• Editorial overview: Molecular & genetic basis of disease.
  Current opinion in genetics & development. 2017 Jun;44:iv-vi Epub 2017 May 2; Authors: Bonini NM, Lee EB, Wasco W, Roses AD

• A protocol for manual segmentation of medial temporal lobe subregions in 7 Tesla MRI.
  NeuroImage. Clinical. 2017;15:466-482 Epub 2017 May 26; Authors: Berron D, Vieweg P, Hochkeppler A, Pluta JB, Ding SL, Maass A, Luther A, Xie L, Das SR, Wolk DA, Wolbers T, Yushkevich PA, Düzel E, Wisse LEM

• How to Look for Thyroid Cancer.
  JAMA. 2017 May 9;317(18):1840-1841; Authors: Cappola AR

• Response to the Letter by Choy.
  The Journal of clinical endocrinology and metabolism. 2017 Apr 1;102(4):1409-1410; Authors: Chaker L, Cappola AR, Rodondi N, Peeters RP, Thyroid Studies Collaboration

• Evaluating the Patterns of Aging-Related Tau Astrogliopathy Unravels Novel Insights Into Brain Aging and Neurodegenerative Diseases.
  Journal of neuropathology and experimental neurology. 2017 Apr 1;76(4):270-288; Authors: Kovacs GG, Robinson JL, Xie SX, Lee EB, Grossman M, Wolk DA, Irwin DJ, Weintraub D, Kim CF, Schuck T, Yousef A, Wagner ST, Suh E, Van Deerlin VM, Lee VM, Trojanowski JQ

• Effects of the Insulin Sensitizer Metformin in Alzheimer Disease: Pilot Data From a Randomized Placebo-controlled Crossover Study.
  Alzheimer disease and associated disorders. 2017 Apr-Jun;31(2):107-113; Authors: Koenig AM, Mechanic-Hamilton D, Xie SX, Combs MF, Cappola AR, Xie L, Detre JA, Wolk DA, Arnold SE

• Mutual reinforcement between telomere capping and canonical Wnt signalling in the intestinal stem cell niche.
  Nature communications. 2017 Mar 17;8:14766; Authors: Yang TB, Chen Q, Deng JT, Jagannathan G, Tobias JW, Schultz DC, Wang S, Lengner CJ, Rustgi AK, Lynch JP, Johnson FB

• Adding Recognition Discriminability Index to the Delayed Recall Is Useful to Predict Conversion from Mild Cognitive Impairment to Alzheimer's Disease in the Alzheimer's Disease Neuroimaging Initiative.
  Frontiers in aging neuroscience. 2017;9:46 Epub 2017 Mar 10; Authors: Russo MJ, Campos J, Vázquez S, Sevlever G, Allegri RF, Alzheimer's Disease Neuroimaging Initiative

• A quantitative meta-analysis of olfactory dysfunction in mild cognitive impairment.
  Journal of neurology, neurosurgery, and psychiatry. 2017 Mar;88(3):226-232 Epub 2016 Dec 30; Authors: Roalf DR, Moberg MJ, Turetsky BI, Brennan L, Kabadi S, Wolk DA, Moberg PJ

• Decision-Making Deficits Associated with Amyloidosis in Lewy Body Disorders.
  Frontiers in human neuroscience. 2016;10:693 Epub 2017 Jan 11; Authors: Spotorno N, McMillan CT, Irwin DJ, Clark R, Lee EB, Trojanowski JQ, Weintraub D, Grossman M

• Medial temporal lobe subregional morphometry using high resolution MRI in Alzheimer's disease.
  Neurobiology of aging. 2017 Jan;49:204-213 Epub 2016 Sep 30; Authors: Wolk DA, Das SR, Mueller SG, Weiner MW, Yushkevich PA, Alzheimer's Disease Neuroimaging Initiative

• Odor Identification Screening Improves Diagnostic Classification in Incipient Alzheimer's Disease.
  Journal of Alzheimer's disease : JAD. 2017;55(4):1497-1507; Authors: Quarmley M, Moberg PJ, Mechanic-Hamilton D, Kabadi S, Arnold SE, Wolk DA, Roalf DR

• Neuropathological and genetic correlates of survival and dementia onset in synucleinopathies: a retrospective analysis.
  The Lancet. Neurology. 2017 Jan;16(1):55-65; Authors: Irwin DJ, Grossman M, Weintraub D, Hurtig HI, Duda JE, Xie SX, Lee EB, Van Deerlin VM, Lopez OL, Kofler JK, Nelson PT, Jicha GA, Woltjer R, Quinn JF, Kaye J, Leverenz JB, Tsuang D, Longfellow K, Yearout D, Kukull W, Keene CD, Montine TJ, Zabetian CP, Trojanowski JQ

• Multi-template analysis of human perirhinal cortex in brain MRI: Explicitly accounting for anatomical variability.
  NeuroImage. 2017 Jan 1;144(Pt A):183-202 Epub 2016 Oct 1; Authors: Xie L, Pluta JB, Das SR, Wisse LEM, Wang H, Mancuso L, Kliot D, Avants BB, Ding SL, Manjón JV, Wolk DA, Yushkevich PA

• Alzheimer's disease: The influence of age on clinical heterogeneity through the human brain connectome.
  Alzheimer's & dementia (Amsterdam, Netherlands). 2017;6:122-135 Epub 2016 Dec 22; Authors: Dickerson BC, Brickhouse M, McGinnis S, Wolk DA

• Introduction to special edition, "State of the Field: Advances in Neuroimaging from the 2016 Alzheimer's Imaging Consortium".
  Alzheimer's & dementia (Amsterdam, Netherlands). 2016;5:67-69 Epub 2016 Dec 21; Authors: Mormino EC, Wolk DA, Apostolova LG

• Neural signatures of experience-based improvements in deterministic decision-making.
  Behavioural brain research. 2016 Dec 15;315:51-65 Epub 2016 Aug 11; Authors: Tremel JJ, Laurent PA, Wolk DA, Wheeler ME, Fiez JA

• HnRNPA2 is a novel histone acetyltransferase that mediates mitochondrial stress-induced nuclear gene expression.
  Cell discovery. 2016;2:16045 Epub 2016 Dec 6; Authors: Guha M, Srinivasan S, Guja K, Mejia E, Garcia-Diaz M, Johnson FB, Ruthel G, Kaufman BA, Rappaport EF, Glineburg MR, Fang JK, Klein-Szanto AJ, Klein Szanto A, Nakagawa H, Basha J, Kundu T, Avadhani NG

• Defining and validating a short form Montreal Cognitive Assessment (s-MoCA) for use in neurodegenerative disease.
  Journal of neurology, neurosurgery, and psychiatry. 2016 Dec;87(12):1303-1310 Epub 2016 Apr 12; Authors: Roalf DR, Moore TM, Wolk DA, Arnold SE, Mechanic-Hamilton D, Rick J, Kabadi S, Ruparel K, Chen-Plotkin AS, Chahine LM, Dahodwala NA, Duda JE, Weintraub DA, Moberg PJ

• Multimodal evaluation demonstrates in vivo (18)F-AV-1451 uptake in autopsy-confirmed corticobasal degeneration.
  Acta neuropathologica. 2016 Dec;132(6):935-937 Epub 2016 Nov 4; Authors: McMillan CT, Irwin DJ, Nasrallah I, Phillips JS, Spindler M, Rascovsky K, Ternes K, Jester C, Wolk DA, Kwong LK, Lee VM, Lee EB, Trojanowski JQ, Grossman M

• HMGB2 orchestrates the chromatin landscape of senescence-associated secretory phenotype gene loci.
  The Journal of cell biology. 2016 Nov 7;215(3):325-334 Epub 2016 Oct 31; Authors: Aird KM, Iwasaki O, Kossenkov AV, Tanizawa H, Fatkhutdinov N, Bitler BG, Le L, Alicea G, Yang TL, Johnson FB, Noma KI, Zhang R

• Thyroid Function Within the Reference Range and the Risk of Stroke: An Individual Participant Data Analysis.
  The Journal of clinical endocrinology and metabolism. 2016 Nov;101(11):4270-4282 Epub 2016 Sep 7; Authors: Chaker L, Baumgartner C, den Elzen WP, Collet TH, Ikram MA, Blum MR, Dehghan A, Drechsler C, Luben RN, Portegies ML, Iervasi G, Medici M, Stott DJ, Dullaart RP, Ford I, Bremner A, Newman AB, Wanner C, Sgarbi JA, Dörr M, Longstreth WT Jr, Psaty BM, Ferrucci L, Maciel RM, Westendorp RG, Jukema JW, Ceresini G, Imaizumi M, Hofman A, Bakker SJ, Franklyn JA, Khaw KT, Bauer DC, Walsh JP, Razvi S, Gussekloo J, Völzke H, Franco OH, Cappola AR, Rodondi N, Peeters RP, Thyroid Studies Collaboration

• Cognitive reserve in frontotemporal degeneration: Neuroanatomic and neuropsychological evidence.
  Neurology. 2016 Oct 25;87(17):1813-1819 Epub 2016 Sep 28; Authors: Placek K, Massimo L, Olm C, Ternes K, Firn K, Van Deerlin V, Lee EB, Trojanowski JQ, Lee VM, Irwin D, Grossman M, McMillan CT

• Thyroid-Stimulating Hormone in the Evaluation of Subclinical Hypothyroidism.
  JAMA. 2016 Oct 18;316(15):1592-1593; Authors: Papaleontiou M, Cappola AR

• Presence of cerebral amyloid modulates phenotype and pattern of neurodegeneration in early Parkinson's disease.
  Journal of neurology, neurosurgery, and psychiatry. 2016 Oct;87(10):1112-22 Epub 2016 Jun 9; Authors: McMillan CT, Wolk DA

• Accounting for the Confound of Meninges in Segmenting Entorhinal and Perirhinal Cortices in T1-Weighted MRI.
  Medical image computing and computer-assisted intervention : MICCAI ... International Conference on Medical Image Computing and Computer-Assisted Intervention. 2016 Oct;9901:564-571 Epub 2016 Oct 2; Authors: Xie L, Wisse LEM, Das SR, Wang H, Wolk DA, Manjón JV, Yushkevich PA

• Multimodal imaging evidence of pathology-mediated disease distribution in corticobasal syndrome.
  Neurology. 2016 Sep 20;87(12):1227-34 Epub 2016 Aug 19; Authors: McMillan CT, Boyd C, Gross RG, Weinstein J, Firn K, Toledo JB, Rascovsky K, Shaw L, Wolk DA, Irwin DJ, Lee EB, Trojanowski JQ, Grossman M

• A Phase II Study of Fornix Deep Brain Stimulation in Mild Alzheimer's Disease.
  Journal of Alzheimer's disease : JAD. 2016 Sep 6;54(2):777-87; Authors: Lozano AM, Fosdick L, Chakravarty MM, Leoutsakos JM, Munro C, Oh E, Drake KE, Lyman CH, Rosenberg PB, Anderson WS, Tang-Wai DF, Pendergrass JC, Salloway S, Asaad WF, Ponce FA, Burke A, Sabbagh M, Wolk DA, Baltuch G, Okun MS, Foote KD, McAndrews MP, Giacobbe P, Targum SD, Lyketsos CG, Smith GS

• Enhancing a Wnt-Telomere Feedback Loop Restores Intestinal Stem Cell Function in a Human Organotypic Model of Dyskeratosis Congenita.
  Cell stem cell. 2016 Sep 1;19(3):397-405 Epub 2016 Aug 18; Authors: Woo DH, Chen Q, Yang TL, Glineburg MR, Hoge C, Leu NA, Johnson FB, Lengner CJ

• Changes in the Transcriptome of Human Astrocytes Accompanying Oxidative Stress-Induced Senescence.
  Frontiers in aging neuroscience. 2016;8:208 Epub 2016 Aug 31; Authors: Crowe EP, Tuzer F, Gregory BD, Donahue G, Gosai SJ, Cohen J, Leung YY, Yetkin E, Nativio R, Wang LS, Sell C, Bonini NM, Berger SL, Johnson FB, Torres C

• Structural and Functional Role of Acetyltransferase hMOF K274 Autoacetylation.
  The Journal of biological chemistry. 2016 Aug 26;291(35):18190-8 Epub 2016 Jul 5; Authors: McCullough CE, Song S, Shin MH, Johnson FB, Marmorstein R

• Osteoporosis Therapy in Postmenopausal Women With High Risk of Fracture.
  JAMA. 2016 Aug 16;316(7):715-6; Authors: Cappola AR, Shoback DM

• Within-Individual Variability: An Index for Subtle Change in Neurocognition in Mild Cognitive Impairment.
  Journal of Alzheimer's disease : JAD. 2016 Aug 10;54(1):325-35; Authors: Roalf DR, Quarmley M, Mechanic-Hamilton D, Wolk DA, Arnold SE, Moberg PJ, Alzheimer’s Disease Neuroimaging Initiative

• Automated Hippocampal Subfield Segmentation at 7T MRI.
  AJNR. American journal of neuroradiology. 2016 Jun;37(6):1050-7 Epub 2016 Feb 4; Authors: Wisse LE, Kuijf HJ, Honingh AM, Wang H, Pluta JB, Das SR, Wolk DA, Zwanenburg JJ, Yushkevich PA, Geerlings MI

• Short-Term Memory Depends on Dissociable Medial Temporal Lobe Regions in Amnestic Mild Cognitive Impairment.
  Cerebral cortex (New York, N.Y. : 1991). 2016 May;26(5):2006-17 Epub 2015 Feb 27; Authors: Das SR, Mancuso L, Olson IR, Arnold SE, Wolk DA

• Conflict or Confluence of Interest?--Reply.
  JAMA. 2016 Apr 26;315(16):1793-4; Authors: Cappola AR, FitzGerald GA

• White matter hyperintensities are more highly associated with preclinical Alzheimer's disease than imaging and cognitive markers of neurodegeneration.
  Alzheimer's & dementia (Amsterdam, Netherlands). 2016;4:18-27 Epub 2016 Apr 7; Authors: Kandel BM, Avants BB, Gee JC, McMillan CT, Erus G, Doshi J, Davatzikos C, Wolk DA

• A brain stress test: Cerebral perfusion during memory encoding in mild cognitive impairment.
  NeuroImage. Clinical. 2016;11:388-397 Epub 2016 Mar 2; Authors: Xie L, Dolui S, Das SR, Stockbower GE, Daffner M, Rao H, Yushkevich PA, Detre JA, Wolk DA

• Pathological α-synuclein distribution in subjects with coincident Alzheimer's and Lewy body pathology.
  Acta neuropathologica. 2016 Mar;131(3):393-409 Epub 2015 Dec 31; Authors: Toledo JB, Gopal P, Raible K, Irwin DJ, Brettschneider J, Sedor S, Waits K, Boluda S, Grossman M, Van Deerlin VM, Lee EB, Arnold SE, Duda JE, Hurtig H, Lee VM, Adler CH, Beach TG, Trojanowski JQ

• Multisite assessment of NIA-AA guidelines for the neuropathologic evaluation of Alzheimer's disease.
  Alzheimer's & dementia : the journal of the Alzheimer's Association. 2016 Feb;12(2):164-169 Epub 2015 Aug 29; Authors: Montine TJ, Monsell SE, Beach TG, Bigio EH, Bu Y, Cairns NJ, Frosch M, Henriksen J, Kofler J, Kukull WA, Lee EB, Nelson PT, Schantz AM, Schneider JA, Sonnen JA, Trojanowski JQ, Vinters HV, Zhou XH, Hyman BT

• Deep clinical and neuropathological phenotyping of Pick disease.
  Annals of neurology. 2016 Feb;79(2):272-87 Epub 2015 Dec 25; Authors: Irwin DJ, Brettschneider J, McMillan CT, Cooper F, Olm C, Arnold SE, Van Deerlin VM, Seeley WW, Miller BL, Lee EB, Lee VM, Grossman M, Trojanowski JQ

• Type I Interferons Control Proliferation and Function of the Intestinal Epithelium.
  Molecular and cellular biology. 2016 Jan 25;36(7):1124-35; Authors: Katlinskaya YV, Katlinski KV, Lasri A, Li N, Beiting DP, Durham AC, Yang T, Pikarsky E, Lengner CJ, Johnson FB, Ben-Neriah Y, Fuchs SY

• Semi-Automated Digital Image Analysis of Pick's Disease and TDP-43 Proteinopathy.
  The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society. 2016 Jan;64(1):54-66 Epub 2015 Nov 4; Authors: Irwin DJ, Byrne MD, McMillan CT, Cooper F, Arnold SE, Lee EB, Van Deerlin VM, Xie SX, Lee VM, Grossman M, Trojanowski JQ

• Aging-related tau astrogliopathy (ARTAG): harmonized evaluation strategy.
  Acta neuropathologica. 2016 Jan;131(1):87-102 Epub 2015 Dec 10; Authors: Kovacs GG, Ferrer I, Grinberg LT, Alafuzoff I, Attems J, Budka H, Cairns NJ, Crary JF, Duyckaerts C, Ghetti B, Halliday GM, Ironside JW, Love S, Mackenzie IR, Munoz DG, Murray ME, Nelson PT, Takahashi H, Trojanowski JQ, Ansorge O, Arzberger T, Baborie A, Beach TG, Bieniek KF, Bigio EH, Bodi I, Dugger BN, Feany M, Gelpi E, Gentleman SM, Giaccone G, Hatanpaa KJ, Heale R, Hof PR, Hofer M, Hortobágyi T, Jellinger K, Jicha GA, Ince P, Kofler J, Kövari E, Kril JJ, Mann DM, Matej R, McKee AC, McLean C, Milenkovic I, Montine TJ, Murayama S, Lee EB, Rahimi J, Rodriguez RD, Rozemüller A, Schneider JA, Schultz C, Seeley W, Seilhean D, Smith C, Tagliavini F, Takao M, Thal DR, Toledo JB, Tolnay M, Troncoso JC, Vinters HV, Weis S, Wharton SB, White CL 3rd, Wisniewski T, Woulfe JM, Yamada M, Dickson DW

• C9orf72 BAC Transgenic Mice Display Typical Pathologic Features of ALS/FTD.
  Neuron. 2015 Dec 2;88(5):892-901; Authors: O'Rourke JG, Bogdanik L, Muhammad AKMG, Gendron TF, Kim KJ, Austin A, Cady J, Liu EY, Zarrow J, Grant S, Ho R, Bell S, Carmona S, Simpkinson M, Lall D, Wu K, Daughrity L, Dickson DW, Harms MB, Petrucelli L, Lee EB, Lutz CM, Baloh RH

• Suspected non-AD pathology in mild cognitive impairment.
  Neurobiology of aging. 2015 Dec;36(12):3152-3162 Epub 2015 Sep 7; Authors: Wisse LEM, Butala N, Das SR, Davatzikos C, Dickerson BC, Vaishnavi SN, Yushkevich PA, Wolk DA, Alzheimer's Disease Neuroimaging Initiative

• Confluence, Not Conflict of Interest: Name Change Necessary.
  JAMA. 2015 Nov 3;314(17):1791-2; Authors: Cappola AR, FitzGerald GA

• Transcriptomic Changes Due to Cytoplasmic TDP-43 Expression Reveal Dysregulation of Histone Transcripts and Nuclear Chromatin.
  PloS one. 2015;10(10):e0141836 Epub 2015 Oct 28; Authors: Amlie-Wolf A, Ryvkin P, Tong R, Dragomir I, Suh E, Xu Y, Van Deerlin VM, Gregory BD, Kwong LK, Trojanowski JQ, Lee VM, Wang LS, Lee EB

• P50: A candidate ERP biomarker of prodromal Alzheimer's disease.
  Brain research. 2015 Oct 22;1624:390-397 Epub 2015 Aug 6; Authors: Green DL, Payne L, Polikar R, Moberg PJ, Wolk DA, Kounios J

• Metabolic and Phenotypic Differences between Mice Producing a Werner Syndrome Helicase Mutant Protein and Wrn Null Mice.
  PloS one. 2015;10(10):e0140292 Epub 2015 Oct 8; Authors: Aumailley L, Garand C, Dubois MJ, Johnson FB, Marette A, Lebel M

• Semi-automated quantification of C9orf72 expansion size reveals inverse correlation between hexanucleotide repeat number and disease duration in frontotemporal degeneration.
  Acta neuropathologica. 2015 Sep;130(3):363-72 Epub 2015 May 29; Authors: Suh E, Lee EB, Neal D, Wood EM, Toledo JB, Rennert L, Irwin DJ, McMillan CT, Krock B, Elman LB, McCluskey LF, Grossman M, Xie SX, Trojanowski JQ, Van Deerlin VM

• Relationship between Carotenoids, Retinol, and Estradiol Levels in Older Women.
  Nutrients. 2015 Aug 5;7(8):6506-19; Authors: Maggio M, de Vita F, Lauretani F, Bandinelli S, Semba RD, Bartali B, Cherubini A, Cappola AR, Ceda GP, Ferrucci L

• Common neuropathological features underlie distinct clinical presentations in three siblings with hereditary diffuse leukoencephalopathy with spheroids caused by CSF1R p.Arg782His.
  Acta neuropathologica communications. 2015 Jul 4;3:42; Authors: Robinson JL, Suh E, Wood EM, Lee EB, Coslett HB, Raible K, Lee VM, Trojanowski JQ, Van Deerlin VM

• Thyroid function within the normal range and risk of coronary heart disease: an individual participant data analysis of 14 cohorts.
  JAMA internal medicine. 2015 Jun;175(6):1037-47; Authors: Åsvold BO, Vatten LJ, Bjøro T, Bauer DC, Bremner A, Cappola AR, Ceresini G, den Elzen WP, Ferrucci L, Franco OH, Franklyn JA, Gussekloo J, Iervasi G, Imaizumi M, Kearney PM, Khaw KT, Maciel RM, Newman AB, Peeters RP, Psaty BM, Razvi S, Sgarbi JA, Stott DJ, Trompet S, Vanderpump MP, Völzke H, Walsh JP, Westendorp RG, Rodondi N, Thyroid Studies Collaboration

• Erratum to: Sequential distribution of pTDP-43 pathology in behavioral variant frontotemporal dementia (bvFTD).
  Acta neuropathologica. 2015 Jun;129(6):929; Authors: Brettschneider J, Del Tredici K, Irwin DJ, Grossman M, Robinson JL, Toledo JB, Lee EB, Fang L, Van Deerlin VM, Ludolph AC, Lee VM, Braak H, Trojanowski JQ

• Subclinical thyroid dysfunction and fracture risk: a meta-analysis.
  JAMA. 2015 May 26;313(20):2055-65; Authors: Blum MR, Bauer DC, Collet TH, Fink HA, Cappola AR, da Costa BR, Wirth CD, Peeters RP, Åsvold BO, den Elzen WP, Luben RN, Imaizumi M, Bremner AP, Gogakos A, Eastell R, Kearney PM, Strotmeyer ES, Wallace ER, Hoff M, Ceresini G, Rivadeneira F, Uitterlinden AG, Stott DJ, Westendorp RG, Khaw KT, Langhammer A, Ferrucci L, Gussekloo J, Williams GR, Walsh JP, Jüni P, Aujesky D, Rodondi N, Thyroid Studies Collaboration

• Prevalence of cerebral amyloid pathology in persons without dementia: a meta-analysis.
  JAMA. 2015 May 19;313(19):1924-38; Authors: Jansen WJ, Ossenkoppele R, Knol DL, Tijms BM, Scheltens P, Verhey FR, Visser PJ, Amyloid Biomarker Study Group, Aalten P, Aarsland D, Alcolea D, Alexander M, Almdahl IS, Arnold SE, Baldeiras I, Barthel H, van Berckel BN, Bibeau K, Blennow K, Brooks DJ, van Buchem MA, Camus V, Cavedo E, Chen K, Chetelat G, Cohen AD, Drzezga A, Engelborghs S, Fagan AM, Fladby T, Fleisher AS, van der Flier WM, Ford L, Förster S, Fortea J, Foskett N, Frederiksen KS, Freund-Levi Y, Frisoni GB, Froelich L, Gabryelewicz T, Gill KD, Gkatzima O, Gómez-Tortosa E, Gordon MF, Grimmer T, Hampel H, Hausner L, Hellwig S, Herukka SK, Hildebrandt H, Ishihara L, Ivanoiu A, Jagust WJ, Johannsen P, Kandimalla R, Kapaki E, Klimkowicz-Mrowiec A, Klunk WE, Köhler S, Koglin N, Kornhuber J, Kramberger MG, Van Laere K, Landau SM, Lee DY, de Leon M, Lisetti V, Lleó A, Madsen K, Maier W, Marcusson J, Mattsson N, de Mendonça A, Meulenbroek O, Meyer PT, Mintun MA, Mok V, Molinuevo JL, Møllergård HM, Morris JC, Mroczko B, Van der Mussele S, Na DL, Newberg A, Nordberg A, Nordlund A, Novak GP, Paraskevas GP, Parnetti L, Perera G, Peters O, Popp J, Prabhakar S, Rabinovici GD, Ramakers IH, Rami L, Resende de Oliveira C, Rinne JO, Rodrigue KM, Rodríguez-Rodríguez E, Roe CM, Rot U, Rowe CC, Rüther E, Sabri O, Sanchez-Juan P, Santana I, Sarazin M, Schröder J, Schütte C, Seo SW, Soetewey F, Soininen H, Spiru L, Struyfs H, Teunissen CE, Tsolaki M, Vandenberghe R, Verbeek MM, Villemagne VL, Vos SJ, van Waalwijk van Doorn LJ, Waldemar G, Wallin A, Wallin ÅK, Wiltfang J, Wolk DA, Zboch M, Zetterberg H

• Prevalence of amyloid PET positivity in dementia syndromes: a meta-analysis.
  JAMA. 2015 May 19;313(19):1939-49; Authors: Ossenkoppele R, Jansen WJ, Rabinovici GD, Knol DL, van der Flier WM, van Berckel BN, Scheltens P, Visser PJ, Amyloid PET Study Group, Verfaillie SC, Zwan MD, Adriaanse SM, Lammertsma AA, Barkhof F, Jagust WJ, Miller BL, Rosen HJ, Landau SM, Villemagne VL, Rowe CC, Lee DY, Na DL, Seo SW, Sarazin M, Roe CM, Sabri O, Barthel H, Koglin N, Hodges J, Leyton CE, Vandenberghe R, van Laere K, Drzezga A, Forster S, Grimmer T, Sánchez-Juan P, Carril JM, Mok V, Camus V, Klunk WE, Cohen AD, Meyer PT, Hellwig S, Newberg A, Frederiksen KS, Fleisher AS, Mintun MA, Wolk DA, Nordberg A, Rinne JO, Chételat G, Lleo A, Blesa R, Fortea J, Madsen K, Rodrigue KM, Brooks DJ

• DNA-damage-induced type I interferon promotes senescence and inhibits stem cell function.
  Cell reports. 2015 May 5;11(5):785-797 Epub 2015 Apr 23; Authors: Yu Q, Katlinskaya YV, Carbone CJ, Zhao B, Katlinski KV, Zheng H, Guha M, Li N, Chen Q, Yang T, Lengner CJ, Greenberg RA, Johnson FB, Fuchs SY

• Deep brain stimulation for Alzheimer disease: a decision and cost-effectiveness analysis.
  Journal of neurology. 2015 May;262(5):1191-7 Epub 2015 Mar 6; Authors: Mirsaeedi-Farahani K, Halpern CH, Baltuch GH, Wolk DA, Stein SC

• C9orf72 promoter hypermethylation is neuroprotective: Neuroimaging and neuropathologic evidence.
  Neurology. 2015 Apr 21;84(16):1622-30 Epub 2015 Mar 20; Authors: McMillan CT, Russ J, Wood EM, Irwin DJ, Grossman M, McCluskey L, Elman L, Van Deerlin V, Lee EB

• Frontotemporal lobar degeneration: defining phenotypic diversity through personalized medicine.
  Acta neuropathologica. 2015 Apr;129(4):469-91 Epub 2014 Dec 31; Authors: Irwin DJ, Cairns NJ, Grossman M, McMillan CT, Lee EB, Van Deerlin VM, Lee VM, Trojanowski JQ

• Identification of chimeric antigen receptors that mediate constitutive or inducible proliferation of T cells.
  Cancer immunology research. 2015 Apr;3(4):356-67 Epub 2015 Jan 19; Authors: Frigault MJ, Lee J, Basil MC, Carpenito C, Motohashi S, Scholler J, Kawalekar OU, Guedan S, McGettigan SE, Posey AD Jr, Ang S, Cooper LJ, Platt JM, Johnson FB, Paulos CM, Zhao Y, Kalos M, Milone MC, June CH

• Relationship of contextual cueing and hippocampal volume in amnestic mild cognitive impairment patients and cognitively normal older adults.
  Journal of the International Neuropsychological Society : JINS. 2015 Apr;21(4):285-96 Epub 2015 May 20; Authors: Negash S, Kliot D, Howard DV, Howard JH Jr, Das SR, Yushkevich PA, Pluta JB, Arnold SE, Wolk DA

• Improving the long-term management of benign thyroid nodules.
  JAMA. 2015 Mar 3;313(9):903-4; Authors: Cappola AR, Mandel SJ

• Thyroid function in the euthyroid range and adverse outcomes in older adults.
  The Journal of clinical endocrinology and metabolism. 2015 Mar;100(3):1088-96 Epub 2014 Dec 16; Authors: Cappola AR, Arnold AM, Wulczyn K, Carlson M, Robbins J, Psaty BM

• Automated volumetry and regional thickness analysis of hippocampal subfields and medial temporal cortical structures in mild cognitive impairment.
  Human brain mapping. 2015 Jan;36(1):258-87 Epub 2014 Sep 2; Authors: Yushkevich PA, Pluta JB, Wang H, Xie L, Ding SL, Gertje EC, Mancuso L, Kliot D, Das SR, Wolk DA

• Hypermethylation of repeat expanded C9orf72 is a clinical and molecular disease modifier.
  Acta neuropathologica. 2015 Jan;129(1):39-52 Epub 2014 Nov 12; Authors: Russ J, Liu EY, Wu K, Neal D, Suh E, Irwin DJ, McMillan CT, Harms MB, Cairns NJ, Wood EM, Xie SX, Elman L, McCluskey L, Grossman M, Van Deerlin VM, Lee EB

• Anterior and posterior MTL networks in aging and MCI.
  Neurobiology of aging. 2015 Jan;36 Suppl 1(0 1):S141-50, S150.e1 Epub 2014 Sep 28; Authors: Das SR, Pluta J, Mancuso L, Kliot D, Yushkevich PA, Wolk DA

• Neuropsychological Testing Predicts Cerebrospinal Fluid Amyloid-β in Mild Cognitive Impairment.
  Journal of Alzheimer's disease : JAD. 2015;46(4):901-12; Authors: Kandel BM, Avants BB, Gee JC, Arnold SE, Wolk DA, Alzheimer’s Disease Neuroimaging Initiative1

• Multimodality imaging of Alzheimer disease and other neurodegenerative dementias.
  Journal of nuclear medicine : official publication, Society of Nuclear Medicine. 2014 Dec;55(12):2003-11 Epub 2014 Nov 20; Authors: Nasrallah IM, Wolk DA

• Effects of transdermal testosterone treatment on inflammatory markers in elderly males.
  Endocrine practice : official journal of the American College of Endocrinology and the American Association of Clinical Endocrinologists. 2014 Nov;20(11):1170-7; Authors: Maggio M, Snyder PJ, De Vita F, Ceda GP, Milaneschi Y, Lauretani F, Luci M, Cattabiani C, Peachey H, Valenti G, Cappola AR, Longo DL, Ferrucci L

• Abnormal serine phosphorylation of insulin receptor substrate 1 is associated with tau pathology in Alzheimer's disease and tauopathies.
  Acta neuropathologica. 2014 Nov;128(5):679-89 Epub 2014 Aug 9; Authors: Yarchoan M, Toledo JB, Lee EB, Arvanitakis Z, Kazi H, Han LY, Louneva N, Lee VM, Kim SF, Trojanowski JQ, Arnold SE

• Subject-specific functional parcellation via prior based eigenanatomy.
  NeuroImage. 2014 Oct 1;99:14-27 Epub 2014 May 20; Authors: Dhillon PS, Wolk DA, Das SR, Ungar LH, Gee JC, Avants BB

• A comparison of Aβ amyloid pathology staging systems and correlation with clinical diagnosis.
  Acta neuropathologica. 2014 Oct;128(4):543-50 Epub 2014 Jun 12; Authors: Boluda S, Toledo JB, Irwin DJ, Raible KM, Byrne MD, Lee EB, Lee VM, Trojanowski JQ

• C9orf72 hypermethylation protects against repeat expansion-associated pathology in ALS/FTD.
  Acta neuropathologica. 2014 Oct;128(4):525-41 Epub 2014 May 8; Authors: Liu EY, Russ J, Wu K, Neal D, Suh E, McNally AG, Irwin DJ, Van Deerlin VM, Lee EB

• A nested case-controlled comparison of telomere length and psychological functioning in breast cancer survivors with and without insomnia symptoms.
  Rejuvenation research. 2014 Oct;17(5):453-7; Authors: Garland SN, Palmer C, Donelson M, Gehrman P, Johnson FB, Mao JJ

• Thyroid antibody status, subclinical hypothyroidism, and the risk of coronary heart disease: an individual participant data analysis.
  The Journal of clinical endocrinology and metabolism. 2014 Sep;99(9):3353-62 Epub 2014 Jun 10; Authors: Collet TH, Bauer DC, Cappola AR, Asvold BO, Weiler S, Vittinghoff E, Gussekloo J, Bremner A, den Elzen WP, Maciel RM, Vanderpump MP, Cornuz J, Dörr M, Wallaschofski H, Newman AB, Sgarbi JA, Razvi S, Völzke H, Walsh JP, Aujesky D, Rodondi N, Thyroid Studies Collaboration

• TDP-43 pathology and neuronal loss in amyotrophic lateral sclerosis spinal cord.
  Acta neuropathologica. 2014 Sep;128(3):423-37 Epub 2014 Jun 12; Authors: Brettschneider J, Arai K, Del Tredici K, Toledo JB, Robinson JL, Lee EB, Kuwabara S, Shibuya K, Irwin DJ, Fang L, Van Deerlin VM, Elman L, McCluskey L, Ludolph AC, Lee VM, Braak H, Trojanowski JQ

• Perforant path synaptic loss correlates with cognitive impairment and Alzheimer's disease in the oldest-old.
  Brain : a journal of neurology. 2014 Sep;137(Pt 9):2578-87 Epub 2014 Jul 9; Authors: Robinson JL, Molina-Porcel L, Corrada MM, Raible K, Lee EB, Lee VM, Kawas CH, Trojanowski JQ

• Poly-A binding protein-1 localization to a subset of TDP-43 inclusions in amyotrophic lateral sclerosis occurs more frequently in patients harboring an expansion in C9orf72.
  Journal of neuropathology and experimental neurology. 2014 Sep;73(9):837-45; Authors: McGurk L, Lee VM, Trojanowksi JQ, Van Deerlin VM, Lee EB, Bonini NM

• Association of G-quadruplex forming sequences with human mtDNA deletion breakpoints.
  BMC genomics. 2014 Aug 13;15(1):677; Authors: Dong DW, Pereira F, Barrett SP, Kolesar JE, Cao K, Damas J, Yatsunyk LA, Johnson FB, Kaufman BA

• Subclinical thyroid dysfunction and hip fracture and bone mineral density in older adults: the cardiovascular health study.
  The Journal of clinical endocrinology and metabolism. 2014 Aug;99(8):2657-64 Epub 2014 May 30; Authors: Garin MC, Arnold AM, Lee JS, Robbins J, Cappola AR

• A platform for discovery: The University of Pennsylvania Integrated Neurodegenerative Disease Biobank.
  Alzheimer's & dementia : the journal of the Alzheimer's Association. 2014 Jul;10(4):477-484.e1 Epub 2013 Aug 24; Authors: Toledo JB, Van Deerlin VM, Lee EB, Suh E, Baek Y, Robinson JL, Xie SX, McBride J, Wood EM, Schuck T, Irwin DJ, Gross RG, Hurtig H, McCluskey L, Elman L, Karlawish J, Schellenberg G, Chen-Plotkin A, Wolk D, Grossman M, Arnold SE, Shaw LM, Lee VM, Trojanowski JQ

• Levothyroxine prescription: not as simple as it seems.
  JAMA. 2014 Jun 25;311(24):2532-3; Authors: Cappola AR

• Controlling the metabolic roller coaster in diabetes.
  JAMA. 2014 Jun 11;311(22):2277-8; Authors: Cappola AR, Livingston EH

• Inactivation of yeast Isw2 chromatin remodeling enzyme mimics longevity effect of calorie restriction via induction of genotoxic stress response.
  Cell metabolism. 2014 Jun 3;19(6):952-66 Epub 2014 May 8; Authors: Dang W, Sutphin GL, Dorsey JA, Otte GL, Cao K, Perry RM, Wanat JJ, Saviolaki D, Murakami CJ, Tsuchiyama S, Robison B, Gregory BD, Vermeulen M, Shiekhattar R, Johnson FB, Kennedy BK, Kaeberlein M, Berger SL

• Testosterone, dihydrotestosterone, and incident cardiovascular disease and mortality in the cardiovascular health study.
  The Journal of clinical endocrinology and metabolism. 2014 Jun;99(6):2061-8 Epub 2014 Mar 14; Authors: Shores MM, Biggs ML, Arnold AM, Smith NL, Longstreth WT Jr, Kizer JR, Hirsch CH, Cappola AR, Matsumoto AM

• Methionine restriction activates the retrograde response and confers both stress tolerance and lifespan extension to yeast, mouse and human cells.
  PloS one. 2014;9(5):e97729 Epub 2014 May 15; Authors: Johnson JE, Johnson FB

• CSF Apo-E levels associate with cognitive decline and MRI changes.
  Acta neuropathologica. 2014 May;127(5):621-32 Epub 2014 Jan 3; Authors: Toledo JB, Da X, Weiner MW, Wolk DA, Xie SX, Arnold SE, Davatzikos C, Shaw LM, Trojanowski JQ, Alzheimer’s Disease Neuroimaging Initiative

• Increasing use of vitamin D supplementation in the chronic renal insufficiency cohort study.
  Journal of renal nutrition : the official journal of the Council on Renal Nutrition of the National Kidney Foundation. 2014 May;24(3):186-93 Epub 2014 Mar 7; Authors: Mariani LH, White MT, Shults J, Anderson CA, Feldman HI, Wolf M, Reese PP, Denburg MR, Townsend RR, Lo JC, Cappola AR, Carlow D, Gadegbeku CA, Steigerwalt S, Leonard MB, CRIC Study Investigators

• Mouse models of telomere dysfunction phenocopy skeletal changes found in human age-related osteoporosis.
  Disease models & mechanisms. 2014 May;7(5):583-92 Epub 2014 Mar 13; Authors: Brennan TA, Egan KP, Lindborg CM, Chen Q, Sweetwyne MT, Hankenson KD, Xie SX, Johnson FB, Pignolo RJ

• Subclinical hypothyroidism, weight change, and body composition in the elderly: the Cardiovascular Health Study.
  The Journal of clinical endocrinology and metabolism. 2014 Apr;99(4):1220-6 Epub 2014 Jan 16; Authors: Garin MC, Arnold AM, Lee JS, Tracy RP, Cappola AR

• Neuronal injury biomarkers and prognosis in ADNI subjects with normal cognition.
  Acta neuropathologica communications. 2014 Mar 6;2:26; Authors: Toledo JB, Weiner MW, Wolk DA, Da X, Chen K, Arnold SE, Jagust W, Jack C, Reiman EM, Davatzikos C, Shaw LM, Trojanowski JQ, Alzheimer’s Disease Neuroimaging Initiative

• Modeling Bivariate Longitudinal Hormone Profiles by Hierarchical State Space Models.
  Journal of the American Statistical Association. 2014 Jan 1;109(505):108-118; Authors: Liu Z, Cappola AR, Crofford LJ, Guo W

• The neuropathology of obesity: insights from human disease.
  Acta neuropathologica. 2014 Jan;127(1):3-28 Epub 2013 Oct 6; Authors: Lee EB, Mattson MP

• Detection of G-quadruplex DNA in mammalian cells.
  Nucleic acids research. 2014 Jan;42(2):860-9 Epub 2013 Oct 24; Authors: Henderson A, Wu Y, Huang YC, Chavez EA, Platt J, Johnson FB, Brosh RM Jr, Sen D, Lansdorp PM

• Comparative survey of the topographical distribution of signature molecular lesions in major neurodegenerative diseases.
  The Journal of comparative neurology. 2013 Dec 15;521(18):4339-55; Authors: Arnold SE, Toledo JB, Appleby DH, Xie SX, Wang LS, Baek Y, Wolk DA, Lee EB, Miller BL, Lee VM, Trojanowski JQ

• Recognition memory in amnestic-mild cognitive impairment: insights from event-related potentials.
  Frontiers in aging neuroscience. 2013;5:89 Epub 2013 Dec 11; Authors: Wolk DA, Manning K, Kliot D, Arnold SE

• R-Spondin 1 promotes vibration-induced bone formation in mouse models of osteoporosis.
  Journal of molecular medicine (Berlin, Germany). 2013 Dec;91(12):1421-9 Epub 2013 Aug 24; Authors: Wang H, Brennan TA, Russell E, Kim JH, Egan KP, Chen Q, Israelite C, Schultz DC, Johnson FB, Pignolo RJ

• Amyloid imaging in atypical presentations of Alzheimer's disease.
  Current neurology and neuroscience reports. 2013 Dec;13(12):412; Authors: Wolk DA

• Integration and relative value of biomarkers for prediction of MCI to AD progression: spatial patterns of brain atrophy, cognitive scores, APOE genotype and CSF biomarkers.
  NeuroImage. Clinical. 2014;4:164-73 Epub 2013 Nov 28; Authors: Da X, Toledo JB, Zee J, Wolk DA, Xie SX, Ou Y, Shacklett A, Parmpi P, Shaw L, Trojanowski JQ, Davatzikos C, Alzheimer's Neuroimaging Initiative

• Testosterone therapy and risk of cardiovascular disease in men.
  JAMA. 2013 Nov 6;310(17):1805-6; Authors: Cappola AR

• Development and validation of pedigree classification criteria for frontotemporal lobar degeneration.
  JAMA neurology. 2013 Nov;70(11):1411-7; Authors: Wood EM, Falcone D, Suh E, Irwin DJ, Chen-Plotkin AS, Lee EB, Xie SX, Van Deerlin VM, Grossman M

• Association of plasma C-reactive protein levels with the diagnosis of Alzheimer's disease.
  Journal of the neurological sciences. 2013 Oct 15;333(1-2):9-12 Epub 2013 Aug 23; Authors: Yarchoan M, Louneva N, Xie SX, Swenson FJ, Hu W, Soares H, Trojanowski JQ, Lee VM, Kling MA, Shaw LM, Chen-Plotkin A, Wolk DA, Arnold SE

• Analysis of nonlinear gene expression progression reveals extensive pathway and age-specific transitions in aging human brains.
  PloS one. 2013;8(10):e74578 Epub 2013 Oct 3; Authors: Cao K, Ryvkin P, Hwang YC, Johnson FB, Wang LS

• Resilient brain aging: characterization of discordance between Alzheimer's disease pathology and cognition.
  Current Alzheimer research. 2013 Oct;10(8):844-51; Authors: Negash S, Wilson RS, Leurgans SE, Wolk DA, Schneider JA, Buchman AS, Bennett DA, Arnold SE

• Comparative accuracies of two common screening instruments for classification of Alzheimer's disease, mild cognitive impairment, and healthy aging.
  Alzheimer's & dementia : the journal of the Alzheimer's Association. 2013 Sep;9(5):529-37 Epub 2012 Dec 21; Authors: Roalf DR, Moberg PJ, Xie SX, Wolk DA, Moelter ST, Arnold SE

• Stages of pTDP-43 pathology in amyotrophic lateral sclerosis.
  Annals of neurology. 2013 Jul;74(1):20-38 Epub 2013 Jun 19; Authors: Brettschneider J, Del Tredici K, Toledo JB, Robinson JL, Irwin DJ, Grossman M, Suh E, Van Deerlin VM, Wood EM, Baek Y, Kwong L, Lee EB, Elman L, McCluskey L, Fang L, Feldengut S, Ludolph AC, Lee VM, Braak H, Trojanowski JQ

• Rap1 relocalization contributes to the chromatin-mediated gene expression profile and pace of cell senescence.
  Genes & development. 2013 Jun 15;27(12):1406-20 Epub 2013 Jun 11; Authors: Platt JM, Ryvkin P, Wanat JJ, Donahue G, Ricketts MD, Barrett SP, Waters HJ, Song S, Chavez A, Abdallah KO, Master SR, Wang LS, Johnson FB

• Aging and endocrinology. Preface.
  Endocrinology and metabolism clinics of North America. 2013 Jun;42(2):xvii-xviii Epub 2013 Apr 9; Authors: Cappola AR

• Topography of FUS pathology distinguishes late-onset BIBD from aFTLD-U.
  Acta neuropathologica communications. 2013 May 9;1(9):1-11; Authors: Lee EB, Russ J, Jung H, Elman LB, Chahine LM, Kremens D, Miller BL, Branch Coslett H, Trojanowski JQ, Van Deerlin VM, McCluskey LF

• Cognitive and functional resilience despite molecular evidence of Alzheimer's disease pathology.
  Alzheimer's & dementia : the journal of the Alzheimer's Association. 2013 May;9(3):e89-95 Epub 2012 Nov 2; Authors: Negash S, Xie S, Davatzikos C, Clark CM, Trojanowski JQ, Shaw LM, Wolk DA, Arnold SE

• Familiarity-based memory as an early cognitive marker of preclinical and prodromal AD.
  Neuropsychologia. 2013 May;51(6):1094-102 Epub 2013 Mar 6; Authors: Wolk DA, Mancuso L, Kliot D, Arnold SE, Dickerson BC

• Clinical review: The human experience with ghrelin administration.
  The Journal of clinical endocrinology and metabolism. 2013 May;98(5):1826-37 Epub 2013 Mar 26; Authors: Garin MC, Burns CM, Kaul S, Cappola AR

• Arterial spin labeled MRI in prodromal Alzheimer's disease: A multi-site study.
  NeuroImage. Clinical. 2013;2:630-6 Epub 2013 Apr 30; Authors: Wang Z, Das SR, Xie SX, Arnold SE, Detre JA, Wolk DA, Alzheimer's Disease Neuroimaging Initiative

• Long-term functional engraftment of mesenchymal progenitor cells in a mouse model of accelerated aging.
  Stem cells (Dayton, Ohio). 2013 Mar;31(3):607-11; Authors: Singh L, Brennan TA, Kim JH, Egan KP, McMillan EA, Chen Q, Hankenson KD, Zhang Y, Emerson SG, Johnson FB, Pignolo RJ

• Persistent subclinical hypothyroidism and cardiovascular risk in the elderly: the cardiovascular health study.
  The Journal of clinical endocrinology and metabolism. 2013 Feb;98(2):533-40 Epub 2012 Nov 16; Authors: Hyland KA, Arnold AM, Lee JS, Cappola AR

• Cdc13 OB2 dimerization required for productive Stn1 binding and efficient telomere maintenance.
  Structure (London, England : 1993). 2013 Jan 8;21(1):109-120 Epub 2012 Nov 21; Authors: Mason M, Wanat JJ, Harper S, Schultz DC, Speicher DW, Johnson FB, Skordalakes E

• Can MRI screen for CSF biomarkers in neurodegenerative disease?
  Neurology. 2013 Jan 8;80(2):132-8 Epub 2012 Dec 26; Authors: McMillan CT, Avants B, Irwin DJ, Toledo JB, Wolk DA, Van Deerlin VM, Shaw LM, Trojanoswki JQ, Grossman M

• Cellular, synaptic, and biochemical features of resilient cognition in Alzheimer's disease.
  Neurobiology of aging. 2013 Jan;34(1):157-68 Epub 2012 May 2; Authors: Arnold SE, Louneva N, Cao K, Wang LS, Han LY, Wolk DA, Negash S, Leurgans SE, Schneider JA, Buchman AS, Wilson RS, Bennett DA

• Increased functional connectivity within medial temporal lobe in mild cognitive impairment.
  Hippocampus. 2013 Jan;23(1):1-6 Epub 2012 Jul 20; Authors: Das SR, Pluta J, Mancuso L, Kliot D, Orozco S, Dickerson BC, Yushkevich PA, Wolk DA

• Frequency and clinicopathological characteristics of presenilin 1 Gly206Ala mutation in Puerto Rican Hispanics with dementia.
  Journal of Alzheimer's disease : JAD. 2013;33(4):1089-95; Authors: Arnold SE, Vega IE, Karlawish JH, Wolk DA, Nunez J, Negron M, Xie SX, Wang LS, Dubroff JG, McCarty-Wood E, Trojanowski JQ, Van Deerlin V

• Vascular disease and dementias: paradigm shifts to drive research in new directions.
  Alzheimer's & dementia : the journal of the Alzheimer's Association. 2013 Jan;9(1):76-92 Epub 2012 Nov 22; Authors: Kling MA, Trojanowski JQ, Wolk DA, Lee VM, Arnold SE

• Relationship between plasma analytes and SPARE-AD defined brain atrophy patterns in ADNI.
  PloS one. 2013;8(2):e55531 Epub 2013 Feb 8; Authors: Toledo JB, Da X, Bhatt P, Wolk DA, Arnold SE, Shaw LM, Trojanowski JQ, Davatzikos C, Alzheimer’s Disease Neuroimaging Initiative

• Physical performance and frailty in chronic kidney disease.
  American journal of nephrology. 2013;38(4):307-15 Epub 2013 Oct 4; Authors: Reese PP, Cappola AR, Shults J, Townsend RR, Gadegbeku CA, Anderson C, Baker JF, Carlow D, Sulik MJ, Lo JC, Go AS, Ky B, Mariani L, Feldman HI, Leonard MB, CRIC Study Investigators

• Longitudinal changes in thyroid function in the oldest old and survival: the cardiovascular health study all-stars study.
  The Journal of clinical endocrinology and metabolism. 2012 Nov;97(11):3944-50 Epub 2012 Aug 9; Authors: Waring AC, Arnold AM, Newman AB, Bùzková P, Hirsch C, Cappola AR

• Factors impacting the departure rates of female and male junior medical school faculty: evidence from a longitudinal analysis.
  Journal of women's health (2002). 2012 Oct;21(10):1059-65 Epub 2012 Sep 24; Authors: Speck RM, Sammel MD, Troxel AB, Cappola AR, Williams-Smith CT, Chittams J, Scott P, Tuton LW, Abbuhl SB

• Amyloid imaging in dementias with atypical presentation.
  Alzheimer's & dementia : the journal of the Alzheimer's Association. 2012 Sep;8(5):389-98 Epub 2012 Jan 30; Authors: Wolk DA, Price JC, Madeira C, Saxton JA, Snitz BE, Lopez OL, Mathis CA, Klunk WE, DeKosky ST

• Amyloid imaging in Alzheimer's disease: comparison of florbetapir and Pittsburgh compound-B positron emission tomography.
  Journal of neurology, neurosurgery, and psychiatry. 2012 Sep;83(9):923-6 Epub 2012 Jul 11; Authors: Wolk DA, Zhang Z, Boudhar S, Clark CM, Pontecorvo MJ, Arnold SE

• Advancing Alzheimer's disease diagnosis, treatment, and care: recommendations from the Ware Invitational Summit.
  Alzheimer's & dementia : the journal of the Alzheimer's Association. 2012 Sep;8(5):445-52; Authors: Naylor MD, Karlawish JH, Arnold SE, Khachaturian AS, Khachaturian ZS, Lee VM, Baumgart M, Banerjee S, Beck C, Blennow K, Brookmeyer R, Brunden KR, Buckwalter KC, Comer M, Covinsky K, Feinberg LF, Frisoni G, Green C, Guimaraes RM, Gwyther LP, Hefti FF, Hutton M, Kawas C, Kent DM, Kuller L, Langa KM, Mahley RW, Maslow K, Masters CL, Meier DE, Neumann PJ, Paul SM, Petersen RC, Sager MA, Sano M, Schenk D, Soares H, Sperling RA, Stahl SM, van Deerlin V, Stern Y, Weir D, Wolk DA, Trojanowski JQ

• Parietal influence on temporal encoding indexed by simultaneous transcranial magnetic stimulation and electroencephalography.
  The Journal of neuroscience : the official journal of the Society for Neuroscience. 2012 Aug 29;32(35):12258-67; Authors: Wiener M, Kliot D, Turkeltaub PE, Hamilton RH, Wolk DA, Coslett HB

• Arterial spin labeling MRI: an emerging biomarker for Alzheimer's disease and other neurodegenerative conditions.
  Current opinion in neurology. 2012 Aug;25(4):421-8; Authors: Wolk DA, Detre JA

• Impairment of osteoblast differentiation due to proliferation-independent telomere dysfunction in mouse models of accelerated aging.
  Aging cell. 2012 Aug;11(4):704-13 Epub 2012 Jun 11; Authors: Wang H, Chen Q, Lee SH, Choi Y, Johnson FB, Pignolo RJ

• The natural history of subclinical hypothyroidism in the elderly: the cardiovascular health study.
  The Journal of clinical endocrinology and metabolism. 2012 Jun;97(6):1962-9 Epub 2012 Mar 21; Authors: Somwaru LL, Rariy CM, Arnold AM, Cappola AR

• Telomere stability and carcinogenesis: an off-again, on-again relationship.
  The Journal of clinical investigation. 2012 Jun;122(6):1962-5 Epub 2012 May 24; Authors: Wanat JJ, Johnson FB

• Pattern of ubiquilin pathology in ALS and FTLD indicates presence of C9ORF72 hexanucleotide expansion.
  Acta neuropathologica. 2012 Jun;123(6):825-39 Epub 2012 Mar 18; Authors: Brettschneider J, Van Deerlin VM, Robinson JL, Kwong L, Lee EB, Ali YO, Safren N, Monteiro MJ, Toledo JB, Elman L, McCluskey L, Irwin DJ, Grossman M, Molina-Porcel L, Lee VM, Trojanowski JQ

• Computational detection and analysis of sequences with duplex-derived interstrand G-quadruplex forming potential.
  Methods (San Diego, Calif.). 2012 May;57(1):3-10 Epub 2012 May 29; Authors: Cao K, Ryvkin P, Johnson FB

• Phosphorylated tau/amyloid beta 1-42 ratio in ventricular cerebrospinal fluid reflects outcome in idiopathic normal pressure hydrocephalus.
  Fluids and barriers of the CNS. 2012 Mar 23;9(1):7; Authors: Patel S, Lee EB, Xie SX, Law A, Jackson EM, Arnold SE, Clark CM, Shaw LM, Grady MS, Trojanowski JQ, Hamilton RH

• Determination of grade and subtype of meningiomas by using histogram analysis of diffusion-tensor imaging metrics.
  Radiology. 2012 Feb;262(2):584-92 Epub 2011 Nov 14; Authors: Wang S, Kim S, Zhang Y, Wang L, Lee EB, Syre P, Poptani H, Melhem ER, Lee JY

• MYST protein acetyltransferase activity requires active site lysine autoacetylation.
  The EMBO journal. 2012 Jan 4;31(1):58-70 Epub 2011 Oct 21; Authors: Yuan H, Rossetto D, Mellert H, Dang W, Srinivasan M, Johnson J, Hodawadekar S, Ding EC, Speicher K, Abshiru N, Perry R, Wu J, Yang C, Zheng YG, Speicher DW, Thibault P, Verreault A, Johnson FB, Berger SL, Sternglanz R, McMahon SB, Côté J, Marmorstein R

• Plasma biomarkers of depressive symptoms in older adults.
  Translational psychiatry. 2012 Jan 3;2(1):e65; Authors: Arnold SE, Xie SX, Leung YY, Wang LS, Kling MA, Han X, Kim EJ, Wolk DA, Bennett DA, Chen-Plotkin A, Grossman M, Hu W, Lee VM, Mackin RS, Trojanowski JQ, Wilson RS, Shaw LM

• Direct comparison of fluorodeoxyglucose positron emission tomography and arterial spin labeling magnetic resonance imaging in Alzheimer's disease.
  Alzheimer's & dementia : the journal of the Alzheimer's Association. 2012 Jan;8(1):51-9 Epub 2011 Oct 21; Authors: Musiek ES, Chen Y, Korczykowski M, Saboury B, Martinez PM, Reddin JS, Alavi A, Kimberg DY, Wolk DA, Julin P, Newberg AB, Arnold SE, Detre JA

• Alzheimer's disease pattern of brain atrophy predicts cognitive decline in Parkinson's disease.
  Brain : a journal of neurology. 2012 Jan;135(Pt 1):170-80 Epub 2011 Nov 21; Authors: Weintraub D, Dietz N, Duda JE, Wolk DA, Doshi J, Xie SX, Davatzikos C, Clark CM, Siderowf A

• Alteration of hypothalamic cellular dynamics in obesity.
  The Journal of clinical investigation. 2012 Jan;122(1):22-5 Epub 2011 Dec 27; Authors: Lee EB, Ahima RS

• Integrated management of type 2 diabetes mellitus and depression treatment to improve medication adherence: a randomized controlled trial.
  Annals of family medicine. 2012 Jan-Feb;10(1):15-22; Authors: Bogner HR, Morales KH, de Vries HF, Cappola AR

• Microvascular perfusion based on arterial spin labeled perfusion MRI as a measure of vascular risk in Alzheimer's disease.
  Journal of Alzheimer's disease : JAD. 2012;32(3):677-87; Authors: Zhang Q, Stafford RB, Wang Z, Arnold SE, Wolk DA, Detre JA

• Obesity, leptin, and Alzheimer's disease.
  Annals of the New York Academy of Sciences. 2011 Dec;1243:15-29; Authors: Lee EB

• Neurodegeneration across stages of cognitive decline in Parkinson disease.
  Archives of neurology. 2011 Dec;68(12):1562-8; Authors: Weintraub D, Doshi J, Koka D, Davatzikos C, Siderowf AD, Duda JE, Wolk DA, Moberg PJ, Xie SX, Clark CM

• Gains or losses: molecular mechanisms of TDP43-mediated neurodegeneration.
  Nature reviews. Neuroscience. 2011 Nov 30;13(1):38-50; Authors: Lee EB, Lee VM, Trojanowski JQ

• Voxel-level comparison of arterial spin-labeled perfusion MRI and FDG-PET in Alzheimer disease.
  Neurology. 2011 Nov 29;77(22):1977-85 Epub 2011 Nov 16; Authors: Chen Y, Wolk DA, Reddin JS, Korczykowski M, Martinez PM, Musiek ES, Newberg AB, Julin P, Arnold SE, Greenberg JH, Detre JA

• Metabolic dysfunction associated with adiponectin deficiency enhances kainic acid-induced seizure severity.
  The Journal of neuroscience : the official journal of the Society for Neuroscience. 2011 Oct 5;31(40):14361-6; Authors: Lee EB, Warmann G, Dhir R, Ahima RS

• α-Syn suppression reverses synaptic and memory defects in a mouse model of dementia with Lewy bodies.
  The Journal of neuroscience : the official journal of the Society for Neuroscience. 2011 Jul 6;31(27):10076-87; Authors: Lim Y, Kehm VM, Lee EB, Soper JH, Li C, Trojanowski JQ, Lee VM

• Predictors of thyroid hormone initiation in older adults: results from the cardiovascular health study.
  The journals of gerontology. Series A, Biological sciences and medical sciences. 2011 Jul;66(7):809-14 Epub 2011 May 31; Authors: Somwaru LL, Arnold AM, Cappola AR

• Dehydroepiandrosterone sulfate and postmenopausal women.
  Current opinion in endocrinology, diabetes, and obesity. 2011 Jun;18(3):171-6; Authors: Goel RM, Cappola AR

• Intraneuronal APP, not free Aβ peptides in 3xTg-AD mice: implications for tau versus Aβ-mediated Alzheimer neurodegeneration.
  The Journal of neuroscience : the official journal of the Society for Neuroscience. 2011 May 25;31(21):7691-9; Authors: Winton MJ, Lee EB, Sun E, Wong MM, Leight S, Zhang B, Trojanowski JQ, Lee VM

• A medial temporal lobe division of labor: insights from memory in aging and early Alzheimer disease.
  Hippocampus. 2011 May;21(5):461-6; Authors: Wolk DA, Dunfee KL, Dickerson BC, Aizenstein HJ, DeKosky ST

• PinX1 the tail on the chromosome.
  The Journal of clinical investigation. 2011 Apr;121(4):1242-4 Epub 2011 Mar 23; Authors: Johnson FB

• Higher serum free testosterone concentration in older women is associated with greater bone mineral density, lean body mass, and total fat mass: the cardiovascular health study.
  The Journal of clinical endocrinology and metabolism. 2011 Apr;96(4):989-96 Epub 2011 Feb 2; Authors: Rariy CM, Ratcliffe SJ, Weinstein R, Bhasin S, Blackman MR, Cauley JA, Robbins J, Zmuda JM, Harris TB, Cappola AR

• Rudimentary G-quadruplex-based telomere capping in Saccharomyces cerevisiae.
  Nature structural & molecular biology. 2011 Apr;18(4):478-85 Epub 2011 Mar 13; Authors: Smith JS, Chen Q, Yatsunyk LA, Nicoludis JM, Garcia MS, Kranaster R, Balasubramanian S, Monchaud D, Teulade-Fichou MP, Abramowitz L, Schultz DC, Johnson FB

• Homologous recombination-dependent rescue of deficiency in the structural maintenance of chromosomes (Smc) 5/6 complex.
  The Journal of biological chemistry. 2011 Feb 18;286(7):5119-25 Epub 2010 Dec 7; Authors: Chavez A, Agrawal V, Johnson FB

• Dysregulation of the ALS-associated gene TDP-43 leads to neuronal death and degeneration in mice.
  The Journal of clinical investigation. 2011 Feb;121(2):726-38 Epub 2011 Jan 4; Authors: Igaz LM, Kwong LK, Lee EB, Chen-Plotkin A, Swanson E, Unger T, Malunda J, Xu Y, Winton MJ, Trojanowski JQ, Lee VM

• Fractionating verbal episodic memory in Alzheimer's disease.
  NeuroImage. 2011 Jan 15;54(2):1530-9 Epub 2010 Sep 9; Authors: Wolk DA, Dickerson BC, Alzheimer's Disease Neuroimaging Initiative

• The hormonal profile of hip fracture female patients differs from community-dwelling peers over a 1-year follow-up period.
  Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA. 2011 Jan;22(1):339-44 Epub 2010 Mar 4; Authors: Cappola AR, Hawkes WG, Blocher N, Yu-Yahiro J, Orwig D, Fredman L, Miller RR, Guralnik JM, Magaziner J

• Effects of metformin and leuprolide acetate on insulin resistance and testosterone levels in nondiabetic postmenopausal women: a randomized, placebo-controlled trial.
  Fertility and sterility. 2010 Nov;94(6):2161-6 Epub 2010 Mar 12; Authors: Patel SM, Iqbal N, Kaul S, Ratcliffe SJ, Rickels MR, Reilly MP, Scattergood T, Basu A, Fuller C, Cappola AR

• Lack of shunt response in suspected idiopathic normal pressure hydrocephalus with Alzheimer disease pathology.
  Annals of neurology. 2010 Oct;68(4):535-40; Authors: Hamilton R, Patel S, Lee EB, Jackson EM, Lopinto J, Arnold SE, Clark CM, Basil A, Shaw LM, Xie SX, Grady MS, Trojanowski JQ

• Photo essay. MRI and positron emission tomography findings in Heidenhain variant Creutzfeldt-Jakob disease.
  Journal of neuro-ophthalmology : the official journal of the North American Neuro-Ophthalmology Society. 2010 Sep;30(3):260-2; Authors: Prasad S, Lee EB, Woo JH, Alavi A, Galetta SL

• Temporally distinct neural coding of perceptual similarity and prototype bias.
  Journal of vision. 2010 Aug 16;10(10):12; Authors: Kahn DA, Harris AM, Wolk DA, Aguirre GK

• Apolipoprotein E (APOE) genotype has dissociable effects on memory and attentional-executive network function in Alzheimer's disease.
  Proceedings of the National Academy of Sciences of the United States of America. 2010 Jun 1;107(22):10256-61 Epub 2010 May 17; Authors: Wolk DA, Dickerson BC, Alzheimer's Disease Neuroimaging Initiative

• Sumoylation and the structural maintenance of chromosomes (Smc) 5/6 complex slow senescence through recombination intermediate resolution.
  The Journal of biological chemistry. 2010 Apr 16;285(16):11922-30 Epub 2010 Feb 16; Authors: Chavez A, George V, Agrawal V, Johnson FB

• Olfactory epithelium amyloid-beta and paired helical filament-tau pathology in Alzheimer disease.
  Annals of neurology. 2010 Apr;67(4):462-9; Authors: Arnold SE, Lee EB, Moberg PJ, Stutzbach L, Kazi H, Han LY, Lee VM, Trojanowski JQ

• Altered gene expression in the Werner and Bloom syndromes is associated with sequences having G-quadruplex forming potential.
  Nucleic acids research. 2010 Mar;38(4):1114-22 Epub 2009 Dec 4; Authors: Johnson JE, Cao K, Ryvkin P, Wang LS, Johnson FB

• Cardiovascular disease is associated with greater incident dehydroepiandrosterone sulfate decline in the oldest old: the cardiovascular health study all stars study.
  Journal of the American Geriatrics Society. 2010 Mar;58(3):421-6 Epub 2010 Feb 16; Authors: Sanders JL, Boudreau RM, Cappola AR, Arnold AM, Robbins J, Cushman M, Newman AB

• Inactivation of the Sas2 histone acetyltransferase delays senescence driven by telomere dysfunction.
  The EMBO journal. 2010 Jan 6;29(1):158-70 Epub 2009 Oct 29; Authors: Kozak ML, Chavez A, Dang W, Berger SL, Ashok A, Guo X, Johnson FB

• Examining faculty awards for gender equity and evolving values.
  Journal of general internal medicine. 2010 Jan;25(1):57-60 Epub 2009 Aug 29; Authors: Abbuhl S, Bristol MN, Ashfaq H, Scott P, Tuton LW, Cappola AR, Sonnad SS

• Computational approaches to the detection and analysis of sequences with intramolecular G-quadruplex forming potential.
  Methods in molecular biology (Clifton, N.J.). 2010;608:39-50; Authors: Ryvkin P, Hershman SG, Wang LS, Johnson FB

• Isolation of G-quadruplex DNA using NMM-sepharose affinity chromatography.
  Methods in molecular biology (Clifton, N.J.). 2010;608:207-21; Authors: Smith JS, Johnson FB

• Idiopathic eosinophilic meningoencephalomyelitis following Well syndrome.
  Neurology. 2009 Dec 8;73(23):2037-9; Authors: Turkeltaub PE, Guzman MA, Lee EB, Galetta SL

• Higher serum testosterone concentration in older women is associated with insulin resistance, metabolic syndrome, and cardiovascular disease.
  The Journal of clinical endocrinology and metabolism. 2009 Dec;94(12):4776-84 Epub 2009 Oct 21; Authors: Patel SM, Ratcliffe SJ, Reilly MP, Weinstein R, Bhasin S, Blackman MR, Cauley JA, Sutton-Tyrrell K, Robbins J, Fried LP, Cappola AR

• Trajectories of dehydroepiandrosterone sulfate predict mortality in older adults: the cardiovascular health study.
  The journals of gerontology. Series A, Biological sciences and medical sciences. 2009 Dec;64(12):1268-74 Epub 2009 Aug 27; Authors: Cappola AR, O'Meara ES, Guo W, Bartz TM, Fried LP, Newman AB

• Comparisons of telomere lengths in peripheral blood and cerebellum in Alzheimer's disease.
  Alzheimer's & dementia : the journal of the Alzheimer's Association. 2009 Nov;5(6):463-9; Authors: Lukens JN, Van Deerlin V, Clark CM, Xie SX, Johnson FB

• Hemangiomas of the brachial plexus: a case series.
  Neurosurgery. 2009 Oct;65(4 Suppl):A181-8; Authors: Ranalli NJ, Huang JH, Lee EB, Zhang PJ, Siegelman ES, Zager EL

• Update on amyloid imaging: from healthy aging to Alzheimer's disease.
  Current neurology and neuroscience reports. 2009 Sep;9(5):345-52; Authors: Wolk DA, Klunk W

• Functional unresponsiveness and replicative senescence of myeloid leukemia antigen-specific CD8+ T cells after allogeneic stem cell transplantation.
  Clinical cancer research : an official journal of the American Association for Cancer Research. 2009 Aug 1;15(15):4944-53 Epub 2009 Jul 14; Authors: Beatty GL, Smith JS, Reshef R, Patel KP, Colligon TA, Vance BA, Frey NV, Johnson FB, Porter DL, Vonderheide RH

• Discrimination and reliance on conceptual fluency cues are inversely related in patients with mild Alzheimer's disease.
  Neuropsychologia. 2009 Jul;47(8-9):1865-72 Epub 2009 Mar 4; Authors: Wolk DA, Gold CA, Signoff ED, Budson AE

• Mindfulness Based Stress Reduction: effect on emotional distress in diabetes.
  Practical diabetes international : the journal for diabetes care teams worldwide. 2009 Jul-Aug;26(6):222-224 Epub 2009 Aug 4; Authors: Young LA, Cappola AR, Baime MJ

• Retained surgical sponges after craniotomies: imaging appearances and complications.
  AJNR. American journal of neuroradiology. 2009 Jun;30(6):1270-2 Epub 2009 Feb 12; Authors: Kim AK, Lee EB, Bagley LJ, Loevner LA

• Thyroid transcription factor 1 expression in sellar tumors: a histogenetic marker?
  Journal of neuropathology and experimental neurology. 2009 May;68(5):482-8; Authors: Lee EB, Tihan T, Scheithauer BW, Zhang PJ, Gonatas NK

• High frequency of and factors associated with thyroid hormone over-replacement and under-replacement in men and women aged 65 and over.
  The Journal of clinical endocrinology and metabolism. 2009 Apr;94(4):1342-5 Epub 2009 Jan 6; Authors: Somwaru LL, Arnold AM, Joshi N, Fried LP, Cappola AR

• Telomeres do the (un)twist: helicase actions at chromosome termini.
  Biochimica et biophysica acta. 2009 Apr;1792(4):329-40 Epub 2009 Feb 23; Authors: Chavez A, Tsou AM, Johnson FB

• Timeless Maintains Genomic Stability and Suppresses Sister Chromatid Exchange during Unperturbed DNA Replication.
  The Journal of biological chemistry. 2009 Mar 27;284(13):8777-85 Epub 2008 Dec 28; Authors: Urtishak KA, Smith KD, Chanoux RA, Greenberg RA, Johnson FB, Brown EJ

• Multiple hormonal deficiencies in anabolic hormones are found in frail older women: the Women's Health and Aging studies.
  The journals of gerontology. Series A, Biological sciences and medical sciences. 2009 Feb;64(2):243-8 Epub 2009 Jan 31; Authors: Cappola AR, Xue QL, Fried LP

• Sgs1 RecQ helicase inhibits survival of Saccharomyces cerevisiae cells lacking telomerase and homologous recombination.
  The Journal of biological chemistry. 2008 Oct 31;283(44):29847-58 Epub 2008 Aug 29; Authors: Lee JY, Mogen JL, Chavez A, Johnson FB

• Clinical reasoning: a 42-year-old man with sequential monocular visual loss.
  Neurology. 2008 Oct 21;71(17):e43-9; Authors: Prasad S, Moss HE, Lee EB, Glisson CC, Galetta SL

• Work-life policies for faculty at the top ten medical schools.
  Journal of women's health (2002). 2008 Oct;17(8):1311-20; Authors: Bristol MN, Abbuhl S, Cappola AR, Sonnad SS

• In vivo veritas: using yeast to probe the biological functions of G-quadruplexes.
  Biochimie. 2008 Aug;90(8):1250-63 Epub 2008 Feb 21; Authors: Johnson JE, Smith JS, Kozak ML, Johnson FB

• Activation drives PD-1 expression during vaccine-specific proliferation and following lentiviral infection in macaques.
  European journal of immunology. 2008 May;38(5):1435-45; Authors: Hokey DA, Johnson FB, Smith J, Weber JL, Yan J, Hirao L, Boyer JD, Lewis MG, Makedonas G, Betts MR, Weiner DB

• TDP-43 immunoreactivity in anoxic, ischemic and neoplastic lesions of the central nervous system.
  Acta neuropathologica. 2008 Mar;115(3):305-11 Epub 2007 Dec 18; Authors: Lee EB, Lee VM, Trojanowski JQ, Neumann M

• Defects in telomere maintenance molecules impair osteoblast differentiation and promote osteoporosis.
  Aging cell. 2008 Jan;7(1):23-31 Epub 2007 Nov 20; Authors: Pignolo RJ, Suda RK, McMillan EA, Shen J, Lee SH, Choi Y, Wright AC, Johnson FB

• Exploring human/animal intersections: converging lines of evidence in comparative models of aging.
  Alzheimer's & dementia : the journal of the Alzheimer's Association. 2008 Jan;4(1):1-5 Epub 2007 Dec 21; Authors: Trojanowski JQ, Hendricks JC, Jedrziewski K, Johnson FB, Michel KE, Hess RS, Cancro MP, Sleeper MM, Pignolo R, Teff KL, Aguirre GD, Lee VM, Lawler DF, Pack AI, Davies PF

• Genomic distribution and functional analyses of potential G-quadruplex-forming sequences in Saccharomyces cerevisiae.
  Nucleic acids research. 2008 Jan;36(1):144-56 Epub 2007 Nov 13; Authors: Hershman SG, Chen Q, Lee JY, Kozak ML, Yue P, Wang LS, Johnson FB

• Evidence that a RecQ helicase slows senescence by resolving recombining telomeres.
  PLoS biology. 2007 Jun;5(6):e160; Authors: Lee JY, Kozak M, Martin JD, Pennock E, Johnson FB

• The intersection of cancer and aging: establishing the need for breast cancer rehabilitation.
  Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology. 2007 May;16(5):866-72; Authors: Schmitz KH, Cappola AR, Stricker CT, Sweeney C, Norman SA

• Supranuclear vertical gaze abnormalities in sporadic Creutzfeldt-Jakob disease.
  Journal of the neurological sciences. 2007 Feb 15;253(1-2):69-72 Epub 2007 Jan 17; Authors: Prasad S, Ko MW, Lee EB, Gonatas NK, Stern MB, Galetta S

• Determinants of serum total and free testosterone levels in women over the age of 65 years.
  The Journal of clinical endocrinology and metabolism. 2007 Feb;92(2):509-16 Epub 2006 Nov 7; Authors: Cappola AR, Ratcliffe SJ, Bhasin S, Blackman MR, Cauley J, Robbins J, Zmuda JM, Harris T, Fried LP

• DHEAS levels and mortality in disabled older women: the Women's Health and Aging Study I.
  The journals of gerontology. Series A, Biological sciences and medical sciences. 2006 Sep;61(9):957-62; Authors: Cappola AR, Xue QL, Walston JD, Leng SX, Ferrucci L, Guralnik J, Fried LP

• Insulin sensitizing pharmacotherapy for prevention of myocardial infarction in patients with diabetes mellitus.
  The American journal of cardiology. 2006 Mar 1;97(5):651-4 Epub 2006 Jan 6; Authors: Sauer WH, Cappola AR, Berlin JA, Kimmel SE

• Thyroid status, cardiovascular risk, and mortality in older adults.
  JAMA. 2006 Mar 1;295(9):1033-41; Authors: Cappola AR, Fried LP, Arnold AM, Danese MD, Kuller LH, Burke GL, Tracy RP, Ladenson PW

• Targeting amyloid-beta peptide (Abeta) oligomers by passive immunization with a conformation-selective monoclonal antibody improves learning and memory in Abeta precursor protein (APP) transgenic mice.
  The Journal of biological chemistry. 2006 Feb 17;281(7):4292-9 Epub 2005 Dec 16; Authors: Lee EB, Leng LZ, Zhang B, Kwong L, Trojanowski JQ, Abel T, Lee VM

• Evidence that the S.cerevisiae Sgs1 protein facilitates recombinational repair of telomeres during senescence.
  Nucleic acids research. 2006;34(2):506-16 Epub 2006 Jan 20; Authors: Azam M, Lee JY, Abraham V, Chanoux R, Schoenly KA, Johnson FB

• The role of sensory-motor information in object recognition: evidence from category-specific visual agnosia.
  Brain and language. 2005 Aug;94(2):131-46; Authors: Wolk DA, Coslett HB, Glosser G

• Meningoencephalitis associated with passive immunization of a transgenic murine model of Alzheimer's amyloidosis.
  FEBS letters. 2005 May 9;579(12):2564-8 Epub 2005 Apr 7; Authors: Lee EB, Leng LZ, Lee VM, Trojanowski JQ

• Microtubule-binding drugs offset tau sequestration by stabilizing microtubules and reversing fast axonal transport deficits in a tauopathy model.
  Proceedings of the National Academy of Sciences of the United States of America. 2005 Jan 4;102(1):227-31 Epub 2004 Dec 22; Authors: Zhang B, Maiti A, Shively S, Lakhani F, McDonald-Jones G, Bruce J, Lee EB, Xie SX, Joyce S, Li C, Toleikis PM, Lee VM, Trojanowski JQ

• Modulation of nuclear factor-kappa B activity by indomethacin influences A beta levels but not A beta precursor protein metabolism in a model of Alzheimer's disease.
  The American journal of pathology. 2004 Dec;165(6):2197-206; Authors: Sung S, Yang H, Uryu K, Lee EB, Zhao L, Shineman D, Trojanowski JQ, Lee VM, Praticò D

• Telomere shortening exposes functions for the mouse Werner and Bloom syndrome genes.
  Molecular and cellular biology. 2004 Oct;24(19):8437-46; Authors: Du X, Shen J, Kugan N, Furth EE, Lombard DB, Cheung C, Pak S, Luo G, Pignolo RJ, DePinho RA, Guarente L, Johnson FB

• Early impairment in consciousness predicts mortality after hemispheric ischemic stroke.
  Critical care medicine. 2004 Jan;32(1):241-5; Authors: Cucchiara BL, Kasner SE, Wolk DA, Lyden PD, Knappertz VA, Ashwood T, Odergren T, Nordlund A, CLASS-I Investigators

• Lack of hemispheric dominance for consciousness in acute ischaemic stroke.
  Journal of neurology, neurosurgery, and psychiatry. 2003 Jul;74(7):889-92; Authors: Cucchiara B, Kasner SE, Wolk DA, Lyden PD, Knappertz VA, Ashwood T, Odergren T, Nordlund A

• Hypothyroidism and atherosclerosis.
  The Journal of clinical endocrinology and metabolism. 2003 Jun;88(6):2438-44; Authors: Cappola AR, Ladenson PW

• Genetically modified NT2N human neuronal cells mediate long-term gene expression as CNS grafts in vivo and improve functional cognitive outcome following experimental traumatic brain injury.
  Journal of neuropathology and experimental neurology. 2003 Apr;62(4):368-80; Authors: Watson DJ, Longhi L, Lee EB, Fulp CT, Fujimoto S, Royo NC, Passini MA, Trojanowski JQ, Lee VM, McIntosh TK, Wolfe JH

• Secretion and intracellular generation of truncated Abeta in beta-site amyloid-beta precursor protein-cleaving enzyme expressing human neurons.
  The Journal of biological chemistry. 2003 Feb 14;278(7):4458-66 Epub 2002 Dec 11; Authors: Lee EB, Skovronsky DM, Abtahian F, Doms RW, Lee VM

• Distribution of a lysosomal enzyme in the adult brain by axonal transport and by cells of the rostral migratory stream.
  The Journal of neuroscience : the official journal of the Society for Neuroscience. 2002 Aug 1;22(15):6437-46; Authors: Passini MA, Lee EB, Heuer GG, Wolfe JH