Vinay M. Nadkarni, M.D., M.S.

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Professor of Anesthesiology and Critical Care at the Hospital of the University of Pennsylvania and the Children's Hospital of Philadelphia
Department: Anesthesiology and Critical Care

Contact information
The Children's Hospital of Philadelphia
Department of Anesthesiology and Critical Care Medicine
Suite 8566, Office 8572, 8th Floor Main
Philadelphia, PA 19104
Office: 215-590-7430
Fax: 215-590-4327
B.A. (Zoology)
Duke University, 1979.
M.S. (Physiology)
Georgetown University, 1980.
University of Maryland School of Medicine, 1984.
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Description of Research Expertise

Vinay Nadkarni MD is an Associate Professor of Anesthesia and Pediatrics at the University of Pennsylvania School of Medicine and the director of the pediatric critical care medicine fellowship training program at the Children's Hospital of Philadelphia. He works in a 45-bed tertiary PICU that admits approximately 2700 patients per year. He shares responsibility for patient care and teaching with 15 board certified pediatric intensive care physicians and 15 pediatric critical care fellows. Dr. Nadkarni completed a Masters degree in Physiology at Georgetown University, and his M.D. at the University of Maryland School of Medicine in Baltimore. He completed his pediatric residency, chief residency and critical care fellowship at Children’s National Medical Center in Washington, DC.

Dr Nadkarni has a local, regional, national and international interest in CPR, pediatric resuscitation, and resuscitation education. He has lectured nationally and internationally on resuscitation issues and training. He has been an invited visiting professor and lecturer at numerous academic centers including Adelaide, Beijing, Boston, Budapest, Buffalo, Christchurch, Cleveland, Cincinnati, Dallas, Melbourne, Philadelphia, Sao Paolo, Stavanger, Tokyo, Toronto, Venice and Washington DC. He has served as chairman of the American Heart Association (AHA) National Committee on Pediatric Resuscitation, and the AHA Emergency Cardiovascular Care Committee, a national editor for the Pediatric Advanced Life Support (PALS) training materials, and is currently a member of the AHA Science Advisory and Coordinating Committee. He serves as a member of the International Liaison Committee on Resuscitation (ILCOR) that has recently developed and published advisory statements on resuscitation guidelines for newborns, infants and children in Europe, North America, South America, Southern Africa, Australia, and New Zealand. He is a founding member of the Science Advisory Board of the AHA National Registry of CPR. He has co-chaired international consensus conferences to review and develop a strategy for international registries of CPR events. He was the Co-chair of the 2005 International Consensus Conference on Emergency Cardiovascular Care and Resuscitation Science, and helped to organize the AHA Resuscitation Science Symposia 2003-2006. He serves as President, Board of Directors, AHA Pennsylvania-Delaware Affiliate, and the national Chairman of the AHA’s International Committee. He is a board member of the Citizen CPR Foundation and the World Federation of Pediatric Intensive and Critical Care Societies. He is a Fellow of the American College of Critical Care Medicine, the American Academy of Pediatrics, and the AHA. He also serves on the AHA National Spokesperson Panel.

Dr. Nadkarni balances his clinical and administrative time with investigations of CPR and critical care medicine in the laboratory and clinical outcomes settings. He is an investigator on three NIH research grants. He is a leader in simulation education development on the University of Pennsylvania campus, and has served as an educational consultant to develop infant and child high fidelity simulators. As a member of the Society for Critical Care Medicine for more than 10 years, he has delivered more than 50 presentations at the annual SCCM Education and Scientific Symposia, and received three major SCCM research awards: the 1990 National In-Training Award, the 1999 National Neuroscience Specialty Award, and the 2003 National Pediatric Specialty Award. He is the course director for the 2006 National SCCM Pediatric Critical Care Concepts Course. He has authored more than 60 peer-reviewed manuscripts and 25 book chapters related to the practice of pediatric critical care medicine.

Dr. Nadkarni believes that a healthy academic career must be balanced by a healthy home and family life, a spirit of volunteerism, and good citizenship. He is married to Ellen Deutsch MD, a pediatric Otolaryngologist practicing in Delaware and specializing in laryngotracheal reconstruction, and has 3 children: Lauren 18, Lindsay 15 and Andrew 11. His local and regional service has included the State Abuse Intervention committee, Emergency Medical Services Committee, Child Death Review Committee, and Wilmington Homeless clinic. In addition, he is a board member for the Delaware Chapter of Operation Smile, a national non-profit, non-sectarian medical organization. Over the past 15 years, Dr. Nadkarni has volunteered time to provide pediatric critical care support services on 10 international missions with Operation Smile, including Kenya, Morocco, Philippines, Russia, China, and Colombia and Ecuador.

Selected Publications

Topjian AA, Sutton RM, Reeder RW, Telford R, Meert KL, Yates AR, Morgan RW, Berger JT, Newth CJ, Carcillo JA, McQuillen PS, Harrison RE, Moler FW, Pollack MM, Carpenter TC, Notterman DA, Holubkov R, Dean JM, Nadkarni VM, Berg RA for the Eunice Kennedy Shriver National Institute of Child Health and Human Development Collaborative Pediatric Critical Care Research Network (CPCCRN): The association of immediate post cardiac arrest diastolic hypertension and survival following pediatric cardiac arrest. Resuscitation 141: 88-95, August 2019.

Topjian AA, Telford R, Holubkov R, Nadkarni VM, Berg RA, Dean JM, Moler FW for the Therapeutic Hypotension after Pediatric Cardiac Arrest (THAPCA) Trial Investigators: The association of early post-resuscitation hypotension with discharge survival following targeted temperature management for pediatric in-hospital cardiac arrest. Resuscitation 141: 24-34, August 2019.

Naim, MY, Griffis HM, Burke RV, McNally BF, Song L, Berg RA, Nadkarni VM, Vellano K, Markenson D, Bradley RN, Rossano JW: Race/ethnicity and neighborhood characteristics are associated with bystander: Cardiopulmonary resuscitation in Pediatric out-of-hospital cardiac arrest in the United States: A study from CARES. Journal of the American Heart Association 8(4): e012637, July 2019.

Morgan RW, Landis WP, Marquez A, Graham K, Roberts AL, Lauridsen KG, Wolfe HA, Nadkarni VM, Topjian AA, Berg RA, Kilbaugh TJ, Sutton RM: Hemodynamic effects of chest compression interruptions during pediatric in-hospital cardiopulmonary resuscitation. Resuscitation 139: 1-8, June 2019.

Kirschen MP, Lourie K, Snyder M, Agarwal K, DiDonato P, Kraus B, Madu C, Geddes K, Nadkarni VM, Davis DH, Wolfe HA, Topjian AA: Routine neurological assessments by nurses in the pediatric intensive care unit. Critical Care Nurse 39(3): 20-32, June 2019.

Faustino EV, Hirshberg EL, Asaro LA, Biagas KV, Pinto N, Srinivasan V, Bagdure DN, Steil GM, Coughlin-Wells K, Wypij D, Nadkarni VM, Agus MSD, for the Heart and Lung Failure-Pediatric Insulin Titration (HALF-PINT) Study Investigators: Short-term adverse outcomes associated with hypoglycemia in critically ill children. Critical Care Medicine 47(5): 706-714, May 2019.

Raymond TT, Praestgaard A, Berg RA, Nadkarni VM, Parshuram CS for the American Heart Association’s Get With the Guidelines-Resuscitation Investigators: The association of hospital rate of delayed epinephrine administration with survival to discharge for pediatric nonshockable in-hospital cardiac arrest. Pediatric Critical Care Medicine 20(5): 405-416, May 2019.

Bembea MM, Ng D, Rizkalla N, Rycus P, Lasa J, Dalton H, Topjian AA, Munoz A, Thiagarajan RR, Nadkarni VM, Hunt EA: Outcomes after extracorporeal cardiopulmonary resuscitation of pediatric in-hospital cardiac arrest: A Report from the Get With the Guidelines-Resuscitation and the Extracorporeal Life Support Organization Registries. Critical Care Medicine 47(4): e278-e285, April 2019.

Lautz AJ, Morgan RW, Karlsson M, Mavroudis CD, Ko TS, Licht DJ, Nadkarni VM, Berg RA, Sutton RM, Kilbaugh TJ: Hemodynamic-directed CPR improves neurologic outcomes and mitochondrial function in heart and brain. Critical Care Medicine 47(3): e241-e249, March 2019 Notes: *Lautz and Morgan – co-first authors; +Kilbaugh and Sutton – co-senior authors.

Meert K, Guerguerian AM, Barbaro R, Slomine B, Christensen J, Berger J, Topjian AA, Bembea M, Tabbutt S, Fink, E, Schwartz S, Nadkarni VM, Telford R, Dean M, Moler F: Extracorporeal Cardiopulmonary Resuscitation: one-year survival and neurobehavioral outcome among infants and children with in-hospital cardiac arrest. Critical Care Medicine 47(3): 393-402, March 2019.

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Last updated: 08/12/2019
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