Debbie Cohen, MBBCH
Professor of Medicine (Renal-Electrolyte and Hypertension) at the Hospital of the University of Pennsylvania
Director of Hypertension Programs , Renal Division
Director, Pheochromocytoma/Paraganglioma Program, Hospital of the University Of Pennsylvania
Director of Clinical Research Renal Division, University of Pennsylvania
Department: Medicine
Contact information
One Founders Pavilion
3400 Spruce Street
Philadelphia, PA 19104
3400 Spruce Street
Philadelphia, PA 19104
Office: 2156627544
Email:
debbie.cohen@uphs.upenn.edu
debbie.cohen@uphs.upenn.edu
Links
Penn Kidney Medicine Comprehensive Hypertension Center (ASH-certified)
Penn Kidney Medicine Dialysis Care
Penn Medicine’s Neuroendocrine Tumor Program
Renal-Electrolyte and Hypertension Research Interests--Nephrology Clinical Research
Penn's Renal-Electrolyte and Hypertension Division
Renal-Electrolyte and Hypertension Clinical Trials--Hypertension/SPYRAL HTN-OFF MED and SPYRAL HTN-ON MED
Penn Kidney Medicine Comprehensive Hypertension Center (ASH-certified)
Penn Kidney Medicine Dialysis Care
Penn Medicine’s Neuroendocrine Tumor Program
Renal-Electrolyte and Hypertension Research Interests--Nephrology Clinical Research
Penn's Renal-Electrolyte and Hypertension Division
Renal-Electrolyte and Hypertension Clinical Trials--Hypertension/SPYRAL HTN-OFF MED and SPYRAL HTN-ON MED
Education:
MBBCH ( )
University of Witwatersrand, Johannesburg, South Africa, 1990.
Permanent linkMBBCH ( )
University of Witwatersrand, Johannesburg, South Africa, 1990.
Description of Research Expertise
complex hypertension, adrenal hypertension, pheochromocytoma, chronic kidney diseaseDescription of Clinical Expertise
Chronic kidney disease, complex hypertension, pheochromocytoma,paraganglioma, adrenal hypertension and renovascular hypertensionSelected Publications
Sunderraj A, Cai X, Pasch A, Feinstein M, Mehta R, Srivastava A, Ricardo AC, Cohen DL, Isakova T. : Associations of calciprotein particle maturation time with echocardiographic measures in the CRIC Study. Am J Nephrol. Mar 2026.Dardari ZA, Yao Z, Zhang J, Bakoyannis G, Nan H, Staten LK, Jha KK, Tasdighi E, Jelwan Y, Burka S, Matsushita K, Simonsick EM, Lima JAC, Psaty BM, Cohen DL, Appel LJ, Khera A, Shah AM, Hall ME, Judd SE, Cole SA, Vasan RS, Benjamin EJ, Cawthon PM, Orwoll E, LaMonte MJ, Eaton CB, El Khoudary SR, Thurston RC, Derby CA, Lotufo PA, Bensenor IM, Bittencourt MS, Blaha MJ. : Prospective Associations of Obesity and Obesity Severity With 9 Cardiovascular Outcomes: The Cross-Cohort Collaboration. Circulation. 153(10): 720-735, Mar 2026.
Estrada-Zuniga C, Liang R, Landry B, Alvarez A, Gonzalez-Cantu H, Nascimento da Conceição V, Trevino R, Gius D, Asa SL, Powers J, Prodanov T, Vaidya A, Toledo RA, Bayley JP, Cohen DL, Tischler AS, Pacak K, Li F, Dahia PLM.: Identifying TMEM127-deficient pheochromocytomas/paragangliomas via RET overexpression by immunohistochemistry. Res Sq Feb 2026.
Blinder AR, Sapiro D, Baker JE, Qin Z, Bancos I, Lyden ML, Young WF, Wachtel H, Cohen DL, Kürzinger L, Fassnacht M, Luther JM, Williams TA, Reincke M, Turcu AF, Else T, Giordano TJ, Udager AM, Rainey WE, Nanba K. : Adrenal histologic and genetic characteristics of primary aldosteronism in late adulthood. Eur J Endocrinol. 194(2): 208-216, Feb 2026.
Pregnall AM, Wubbenhorst B, D'Andrea K, Pluta J, Amjad W, Shilan J, Cohen DL, Weathers B, Bennett B, Bonanni M, Montone K, Nathanson KL, Wachtel H.: Metastatic progression of pheochromocytoma and paraganglioma occurs via parallel evolution. NPJ Precis Oncol. Jan 2026.
White WB, Azizi M, Ferdinand K, Cohen DL, Nührenberg T, Lefkowitz M, Jiao R, Rizkala AR, Maboudian M, Williams B. : Natriuretic Peptide Receptor-1 Agonist for Resistant Hypertension: A Randomized Phase 2 Trial. J Am Coll Cardiol. 2026 Jan 13:S0735-1097(25)10351-3. doi: 10.1016/j.jacc.2025.11.045. Epub ahead of print. PMID: 41563174. S0735-1097(25): 10351-10353, Jan 2026.
Estrella MM, Ballew SH, Sang Y, Grams ME, Coresh J, Surapaneni A, Alencar de Pinho N, Ärnlöv J, Brenner H, Carrero JJ, Chen TK, Cohen DL, Cushman M, Gansevoort RT, Hwang SJ, Inker LA, Ix JH, Kabasawa K, Konta T, Lees JS, Polkinghorne KR, Shlipak MG, Vernooij RWM, Wheeler DC, Yadav AK, Levey AS, Eckardt KU; : Chronic Kidney Disease Prognosis Consortium Investigators and Collaborators. Discordance in Creatinine- and Cystatin C-Based eGFR and Clinical Outcomes: A Meta-Analysis. JAMA. 334(21): 1915-1926, Dec 2025.
Tasdighi E, Yao Z, Dardari ZA, Jha KK, Osuji N, Rajan T, Boakye E, Matsushita K, Simonsick EM, Lima JAC, Lloyd-Jones DM, Cohen DL, Appel LJ, Khera A, Hall ME, Rodriguez CJ, Judd S, Cole SA, Ramachandran VS, Benjamin EJ, Lotufo PA, Bittencourt MS, El Khoudary SR, Thurston RC, Derby CA, Psaty BM, Eaton CB, LaMonte MJ, Cawthon PM, Orwoll ES, Bhatnagar A, DeFilippis AP, Blaha MJ. : Association between cigarette smoking status, intensity, and cessation duration with long-term incidence of nine cardiovascular and mortality outcomes: The Cross-Cohort Collaboration (CCC). PLoS Med. 22(11): e1004561, Nov 2025.
Shulman R, Yang W, Cohen DL, Reese PP, Cohen JB; CRIC Study Investigators. : Renin-Angiotensin System Inhibitors in Patients With Nonproteinuric Chronic Kidney Disease and Kidney Outcomes: Findings From the CRIC Study. Kidney Med. 8(1): 101159, Oct 2025.
van Rooyen D, Bandulik S, Coon GA, Laukemper M, Kumar-Sinha C, Udager AM, Lerario AM, Lee C, Wachtel H, Cohen DL, Luther JM, Giordano TJ, Scholl UI, Butz F, Popp B, Turcu AF, Warth R, Rainey WE, Rege J.: Somatic Mutations in MCOLN3 Are Associated With Aldosterone-Producing Adenomas. Hypertension. Aug 2025.