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Mark Alan Rosen, MD, PhD
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Associate Professor of Radiology at the Hospital of the University of Pennsylvania
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Attending Radiologist, Department of Radiology, Hospital of the University of Pennsylvania, Philadelphia, PA
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Medical Staff, Department of Radiology , Penn-Presbyterian Medical Center, Philadelphia, PA
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Medical Staff, Department of Radiology, Pennsylvania Hospital, Philadelphia, PA
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Medical Staff, Department of Radiology, Chester County Hospital
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Department: Radiology
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Contact information
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Department of Radiology
32 Hospital of the University of Pennsylvania
15 1 Silverstein
3a 3400 Spruce Street
Philadelphia, PA 19104-4283
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32 Hospital of the University of Pennsylvania
15 1 Silverstein
3a 3400 Spruce Street
Philadelphia, PA 19104-4283
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Office: 215-662-3107
32 Fax: 215-662-7263
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32 Fax: 215-662-7263
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Publications
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Links
b5 Search PubMed for articles
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b5 Search PubMed for articles
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Education:
21 9 B.A. 16 (Chemistry) c
28 Amherst College, 1986.
21 9 M.D. 15 (Medicine) c
2c Columbia University, 1994.
21 a Ph.D. 19 (Biochemistry) c
2c Columbia University, 1995.
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Permanent link21 9 B.A. 16 (Chemistry) c
28 Amherst College, 1986.
21 9 M.D. 15 (Medicine) c
2c Columbia University, 1994.
21 a Ph.D. 19 (Biochemistry) c
2c Columbia University, 1995.
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2c Morphologic Tumor Response Evaluation
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Description of Research Expertise
40 Functional Tumor MR Imaging: DCE-MRI, DWI, MRSI2c Morphologic Tumor Response Evaluation
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Description of Clinical Expertise
36 Radiology, Abdominal Imaigng, MRI & CT62
Description of Other Expertise
46 Imaging quality assurance, clinical trials methodologye 29
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27d Song I, Thompson EW, Verma A, MacLean MT, Duda J, Elahi A, Tran R, Raghupathy P, Swago S, Hazim M, Bhattaru A, Schneider C, Vujkovic M, Torigian DA, Kahn CE, Gee JC, Borthakur A, Kripke CM, Carson CC, Carr R, Jehangir Q, Ko YA, Litt H, Rosen M, Mankoff DA, Schnall MD, Shou H, Chirinos J, Damrauer SM, Serper M, Chen J, Rader DJ; Penn Medicine BioBank; Witschey WRT, Sagreiya H.: Clinical correlates of CT imaging-derived phenotypes among lean and overweight patients with hepatic steatosis. Sci. Reports 2(14): 53, Jan 2024 Notes: doi: 10.1038/s41598-023-49470-x.
117 Suresh K, Hill PA, Kahn CE Jr, Schnall MD, Rosen MA, Zafar HM, Trerotola SO, Cook TS.: Quality Improvement Report: Design and Implementation of a Radiology E-Consult Service. Radiographics 43(12), Dec 2023.
88 Lee SH, Geng H, Arnold J, Caruana R, Fan Y, Rosen MA, Apte AP, Deasy JO, Bradley JD, Xiao Y. b5 : Interpretable Machine Learning for Choosing Radiation Dose-volume Constraints on Cardio-pulmonary Substructures Associated with Overall Survival in NRG Oncology RTOG 0617 8e Int J Radiat Oncol Biol Phys. 117(5): 1270-1286, Dec 2023 Notes: doi: 10.1016/j.ijrobp.2023.06.009. Epub 2023 Jun 19.
1dc Hall WA, Li J, You YN, Gollub MJ, Grajo JR, Rosen M, dePrisco G, Yothers G, Dorth JA, Rahma OE, Russell MM, Gross HM, Jacobs SA, Faller BA, George S, Al Baghdadi T, Haddock MG, Valicenti R, Hong TS, George TJ.: Prospective Correlation of Magnetic Resonance Tumor Regression Grade With Pathologic Outcomes in Total Neoadjuvant Therapy for Rectal Adenocarcinoma. J Clin Oncol. 10(41): 4643-4651, Oct 2023.
15d Cao J, Pickup S, Rosen M, Zhou R.: Impact of Arterial Input Function and Pharmacokinetic Models on DCE-MRI Biomarkers for Detection of Vascular Effect Induced by Stroma-Directed Drug in an Orthotopic Mouse Model of Pancreatic Cancer. Mol Imaging Biol 25(4): 638-647, Aug 2023.
27d Weiss AR, Chen YL, Scharschmidt TJ, Xue W, Gao Z, Black JO, Choy E, Davis JL, Fanburg-Smith JC, Kao SC, Kayton ML, Kessel S, Lim R, Million L, Okuno SH, Ostrenga A, Parisi MT, Pryma DA, Randall RL, Rosen MA, Shulkin BL, Terezakis S, Venkatramani R, Zambrano E, Wang D, Hawkins DS, Spunt SL.: Outcomes After Preoperative Chemoradiation with or Without Pazopanib in Non-Rhabdomyosarcoma Soft Tissue Sarcoma: A Report from Children's Oncology Group and NRG Oncology. J of Clin Oncology 41(31): 4842-4848, Jul 2023 Notes: doi: 10.1200/JCO.23.00045. Epub 2023 Jul 31.
d8 Boss MA, Snyder BS, Kim E, Flamini D, Englander S, Sundaram KM, Gumpeni N, Palmer SL, Choi H, Froemming AT, Persigehl T, Davenport MS, Malyarenko D, Chenevert TL, Rosen MA. a4 : Repeatability and Reproducibility Assessment of the Apparent Diffusion Coefficient in the Prostate: A Trial of the ECOG-ACRIN Research Group (ACRIN 6701) 78 J Magn Reson Imaging 56(3): 668-679, Sep 2022 Notes: doi: 10.1002/jmri.28093. Epub 2022 Feb 10.
e4 Romanello Joaquim M, Furth EE, Fan Y, Song HK, Pickup S, Cao J, Choi H, Gupta M, Cao Q, Shinohara R, McMenamin D, Clendenin C, Karasic TB, Duda J, Gee JC, O'Dwyer PJ, Rosen MA, Zhou R. 8d : DWI Metrics Differentiating Benign Intraductal Papillary Mucinous Neoplasms from Invasive Pancreatic Cancer: A Study in GEM Models 64 Cancers (Basel) 14(16): 4017, Aug 2022 Notes: doi: 10.3390/cancers14164017.
b7 Mettikanont P, Kalluri A, Bittermann T, Phillips N, Loza BL, Rosen M, Siegelman E, Furth E, Abt P, Olthoff K, Shaked A, Hoteit M, Reddy KR. 7e : The Course of LIRADS 3 and 4 Hepatic Abnormalities as Correlated With Explant Pathology: A Single Center Experience 83 J Clin Exp Hepatol 12(4): 1048-1056, Jul-Aug 2022 Notes: doi: 10.1016/j.jceh.2022.02.005. Epub 2022 Mar 9.
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Selected Publications
155 Gupta M, Choi H, Kemp SB, Furth EE, Pickup S, Clendenin C, Orlen M, Rosen M, Liu F, Cao Q, Stanger BZ, Zhou R: Multimetric MRI Captures Early Response and Acquired Resistance of Pancreatic Cancer to KRAS Inhibitor Therapy. Clin. Cancer Res. 1(31): 2663-2674, Jul 2025.27d Song I, Thompson EW, Verma A, MacLean MT, Duda J, Elahi A, Tran R, Raghupathy P, Swago S, Hazim M, Bhattaru A, Schneider C, Vujkovic M, Torigian DA, Kahn CE, Gee JC, Borthakur A, Kripke CM, Carson CC, Carr R, Jehangir Q, Ko YA, Litt H, Rosen M, Mankoff DA, Schnall MD, Shou H, Chirinos J, Damrauer SM, Serper M, Chen J, Rader DJ; Penn Medicine BioBank; Witschey WRT, Sagreiya H.: Clinical correlates of CT imaging-derived phenotypes among lean and overweight patients with hepatic steatosis. Sci. Reports 2(14): 53, Jan 2024 Notes: doi: 10.1038/s41598-023-49470-x.
117 Suresh K, Hill PA, Kahn CE Jr, Schnall MD, Rosen MA, Zafar HM, Trerotola SO, Cook TS.: Quality Improvement Report: Design and Implementation of a Radiology E-Consult Service. Radiographics 43(12), Dec 2023.
88 Lee SH, Geng H, Arnold J, Caruana R, Fan Y, Rosen MA, Apte AP, Deasy JO, Bradley JD, Xiao Y. b5 : Interpretable Machine Learning for Choosing Radiation Dose-volume Constraints on Cardio-pulmonary Substructures Associated with Overall Survival in NRG Oncology RTOG 0617 8e Int J Radiat Oncol Biol Phys. 117(5): 1270-1286, Dec 2023 Notes: doi: 10.1016/j.ijrobp.2023.06.009. Epub 2023 Jun 19.
1dc Hall WA, Li J, You YN, Gollub MJ, Grajo JR, Rosen M, dePrisco G, Yothers G, Dorth JA, Rahma OE, Russell MM, Gross HM, Jacobs SA, Faller BA, George S, Al Baghdadi T, Haddock MG, Valicenti R, Hong TS, George TJ.: Prospective Correlation of Magnetic Resonance Tumor Regression Grade With Pathologic Outcomes in Total Neoadjuvant Therapy for Rectal Adenocarcinoma. J Clin Oncol. 10(41): 4643-4651, Oct 2023.
15d Cao J, Pickup S, Rosen M, Zhou R.: Impact of Arterial Input Function and Pharmacokinetic Models on DCE-MRI Biomarkers for Detection of Vascular Effect Induced by Stroma-Directed Drug in an Orthotopic Mouse Model of Pancreatic Cancer. Mol Imaging Biol 25(4): 638-647, Aug 2023.
27d Weiss AR, Chen YL, Scharschmidt TJ, Xue W, Gao Z, Black JO, Choy E, Davis JL, Fanburg-Smith JC, Kao SC, Kayton ML, Kessel S, Lim R, Million L, Okuno SH, Ostrenga A, Parisi MT, Pryma DA, Randall RL, Rosen MA, Shulkin BL, Terezakis S, Venkatramani R, Zambrano E, Wang D, Hawkins DS, Spunt SL.: Outcomes After Preoperative Chemoradiation with or Without Pazopanib in Non-Rhabdomyosarcoma Soft Tissue Sarcoma: A Report from Children's Oncology Group and NRG Oncology. J of Clin Oncology 41(31): 4842-4848, Jul 2023 Notes: doi: 10.1200/JCO.23.00045. Epub 2023 Jul 31.
d8 Boss MA, Snyder BS, Kim E, Flamini D, Englander S, Sundaram KM, Gumpeni N, Palmer SL, Choi H, Froemming AT, Persigehl T, Davenport MS, Malyarenko D, Chenevert TL, Rosen MA. a4 : Repeatability and Reproducibility Assessment of the Apparent Diffusion Coefficient in the Prostate: A Trial of the ECOG-ACRIN Research Group (ACRIN 6701) 78 J Magn Reson Imaging 56(3): 668-679, Sep 2022 Notes: doi: 10.1002/jmri.28093. Epub 2022 Feb 10.
e4 Romanello Joaquim M, Furth EE, Fan Y, Song HK, Pickup S, Cao J, Choi H, Gupta M, Cao Q, Shinohara R, McMenamin D, Clendenin C, Karasic TB, Duda J, Gee JC, O'Dwyer PJ, Rosen MA, Zhou R. 8d : DWI Metrics Differentiating Benign Intraductal Papillary Mucinous Neoplasms from Invasive Pancreatic Cancer: A Study in GEM Models 64 Cancers (Basel) 14(16): 4017, Aug 2022 Notes: doi: 10.3390/cancers14164017.
b7 Mettikanont P, Kalluri A, Bittermann T, Phillips N, Loza BL, Rosen M, Siegelman E, Furth E, Abt P, Olthoff K, Shaked A, Hoteit M, Reddy KR. 7e : The Course of LIRADS 3 and 4 Hepatic Abnormalities as Correlated With Explant Pathology: A Single Center Experience 83 J Clin Exp Hepatol 12(4): 1048-1056, Jul-Aug 2022 Notes: doi: 10.1016/j.jceh.2022.02.005. Epub 2022 Mar 9.
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