Mark Alan Rosen, MD, PhD
Associate Professor of Radiology at the Hospital of the University of Pennsylvania
Attending, Department of Radiology, Hospital of the University of Pennsylvania, Philadelphia, PA
Medical Staff, Department of Radiology , Penn-Presbyterian Medical Center, Philadelphia, PA
Medical Staff, Department of Radiology, Pennsylvania Hospital, Philadelphia, PA
Department: Radiology
Contact information
Department of Radiology
Hospital of the University of Pennsylvania
1 Silverstein
3400 Spruce Street
Philadelphia, PA 19104-4283
Hospital of the University of Pennsylvania
1 Silverstein
3400 Spruce Street
Philadelphia, PA 19104-4283
Office: 215-662-3107
Fax: 215-662-7263
Fax: 215-662-7263
Education:
B.A. (Chemistry)
Amherst College, 1986.
M.D. (Medicine)
Columbia University, 1994.
Ph.D. (Biochemistry)
Columbia University, 1994.
Permanent linkB.A. (Chemistry)
Amherst College, 1986.
M.D. (Medicine)
Columbia University, 1994.
Ph.D. (Biochemistry)
Columbia University, 1994.
Description of Research Expertise
Functional Tumor MR Imaging: DCE-MRI, DWI, MRSIMorphologic Tumor Response Evaluation
Description of Clinical Expertise
Radiology, Abdominal Imaigng, MRI & CTSelected Publications
Gupta M, Choi H, Kemp SB, Furth EE, Pickup S, Clendenin C, Orlen M, Rosen M, Liu F, Cao Q, Stanger BZ, Zhou R: Multimetric MRI Captures Early Response and Acquired Resistance of Pancreatic Cancer to KRAS Inhibitor Therapy. Clin. Cancer Res. 1(31): 2663-2674, Jul 2025.Song I, Thompson EW, Verma A, MacLean MT, Duda J, Elahi A, Tran R, Raghupathy P, Swago S, Hazim M, Bhattaru A, Schneider C, Vujkovic M, Torigian DA, Kahn CE, Gee JC, Borthakur A, Kripke CM, Carson CC, Carr R, Jehangir Q, Ko YA, Litt H, Rosen M, Mankoff DA, Schnall MD, Shou H, Chirinos J, Damrauer SM, Serper M, Chen J, Rader DJ; Penn Medicine BioBank; Witschey WRT, Sagreiya H.: Clinical correlates of CT imaging-derived phenotypes among lean and overweight patients with hepatic steatosis. Sci. Reports 2(14), Jan 2024.
Suresh K, Hill PA, Kahn CE Jr, Schnall MD, Rosen MA, Zafar HM, Trerotola SO, Cook TS.: Quality Improvement Report: Design and Implementation of a Radiology E-Consult Service. Radiographics 43(12), Dec 2023.
Lee SH, Geng H, Arnold J, Caruana R, Fan Y, Rosen MA, Apte AP, Deasy JO, Bradley JD, Xiao Y. : Interpretable Machine Learning for Choosing Radiation Dose-volume Constraints on Cardio-pulmonary Substructures Associated with Overall Survival in NRG Oncology RTOG 0617 Int J Radiat Oncol Biol Phys. 117(5): 1270-1286, Dec 2023 Notes: doi: 10.1016/j.ijrobp.2023.06.009. Epub 2023 Jun 19.
Hall WA, Li J, You YN, Gollub MJ, Grajo JR, Rosen M, dePrisco G, Yothers G, Dorth JA, Rahma OE, Russell MM, Gross HM, Jacobs SA, Faller BA, George S, Al Baghdadi T, Haddock MG, Valicenti R, Hong TS, George TJ.: Prospective Correlation of Magnetic Resonance Tumor Regression Grade With Pathologic Outcomes in Total Neoadjuvant Therapy for Rectal Adenocarcinoma. J CLin Oncol. 10(41): 4643-4651, Oct 2023.
Boss MA, Snyder BS, Kim E, Flamini D, Englander S, Sundaram KM, Gumpeni N, Palmer SL, Choi H, Froemming AT, Persigehl T, Davenport MS, Malyarenko D, Chenevert TL, Rosen MA. : Repeatability and Reproducibility Assessment of the Apparent Diffusion Coefficient in the Prostate: A Trial of the ECOG-ACRIN Research Group (ACRIN 6701) J Magn Reson Imaging 56(3): 668-679, Sep 2022 Notes: doi: 10.1002/jmri.28093. Epub 2022 Feb 10.
Romanello Joaquim M, Furth EE, Fan Y, Song HK, Pickup S, Cao J, Choi H, Gupta M, Cao Q, Shinohara R, McMenamin D, Clendenin C, Karasic TB, Duda J, Gee JC, O'Dwyer PJ, Rosen MA, Zhou R. : DWI Metrics Differentiating Benign Intraductal Papillary Mucinous Neoplasms from Invasive Pancreatic Cancer: A Study in GEM Models Cancers (Basel) 14(16): 4017, Aug 2022 Notes: doi: 10.3390/cancers14164017.
Mettikanont P, Kalluri A, Bittermann T, Phillips N, Loza BL, Rosen M, Siegelman E, Furth E, Abt P, Olthoff K, Shaked A, Hoteit M, Reddy KR. : The Course of LIRADS 3 and 4 Hepatic Abnormalities as Correlated With Explant Pathology: A Single Center Experience J Clin Exp Hepatol 12(4): 1048-1056, Jul-Aug 2022 Notes: doi: 10.1016/j.jceh.2022.02.005. Epub 2022 Mar 9.
Wattenberg MM, Asch D, Yu S, O'Dwyer PJ, Domchek SM, Nathanson KL, Rosen MA, Beatty GL, Siegelman ES, Reiss KA: Platinum response characteristics of patients with pancreatic ductal adenocarcinoma and a germline BRCA1, BRCA2 or PALB2 mutation. Br J Cancer 122(3): 333-339, Feb 2020 Notes: doi: 10.1038/s41416-019-0582-7. Epub 2019 Dec 2.
Newitt DC, Zhang Z, Gibbs JE, Partridge SC, Chenevert TL, Rosen MA, Bolan PJ, Marques HS, Aliu S, Li W, Cimino L, Joe BN, Umphrey H, Ojeda-Fournier H, Dogan B, Oh K, Abe H, Drukteinis J, Esserman LJ, Hylton NM; ACRIN Trial Team and I-SPY 2 TRIAL Investigators: Test-retest repeatability and reproducibility of ADC measures by breast DWI: Results from the ACRIN 6698 trial. J Magn Reson Imaging. 49(6): 1617-1628, Jun 2019 Notes: doi: 10.1002/jmri.26539. Epub 2018 Oct 22.