James Treat, M.D.

faculty photo
Professor of Clinical Pediatrics (General Pediatrics)
Attending Dermatologist, Children's Hospital of Philadelphia
Director of Education, Pediatric Dermatology, Children's Hospital of Philadelphia
Associate Chair, IT, Department of Pediatrics, Children's Hospital of Philadelphia
Associate Director, Pediatric Dermatology Fellowship, Children's Hospital of Philadelphia
Department: Pediatrics

Contact information
University of Pennsylvania School of Medicine
Children's Hospital of Philadelphia
HUB 6581
34th and Civic Center Blvd
Philadelphia, PA 19104
Office: 215-590-2159
Fax: 215-590-4948
Education:
BA (Biological Basis of Behavior, minor Anthropology )
University of Pennsylvania, 1997.
MD
University of Pennsylvania, 2002.
Permanent link
 
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Description of Clinical Expertise

Hemangiomas
Capillary Malformations (Port Wine Stains)
Acne
Atopic Dermatitis
Birthmarks
Allergic Contact Dermatitis
Dermatologic manifestations of infectious diseases
Genodermatoses
Melanocytic Nevi
Molluscum
Pigmentary Anomalies
Pediatric Dermatology
Warts

Selected Publications

Braun M, Frieden IJ, Siegel DH, George E, Hess CP, Fox CK, Chamlin SL, Drolet BA, Metry D, Pope E, Powell J, Holland K, Ulschmid C, Liang MG, Barry KK, Ho T, Cotter C, Baselga E, Bosquez D, Jain SN, Bui JK, Lara-Corrales I, Funk T, Small A, Baghoomian W, Yan AC, Treat JR, Hogrogian GS, Huang C, Haggstrom A, List M, McCuaig CC, Barrio V, Mancini AJ, Lawley LP, Grunnet-Satcher K, Horii KA, Newell B, Nopper A, Garzon MC, Scollan ME, Mathes EF. : Multicenter Study of Long-Term Outcomes and Quality of Life in PHACE Syndrome after Age 10. J Pediatr 267(113907), Apr 2024.

Zendt M, Bustos Carrillo FA, Kelly S, Saturday T, DeGrange M, Ginigeme A, Wu L, Callier V, Ortega-Villa A, Faust M, Chang-Rabley E, Bugal K, Kenney H, Khil P, Youn JH, Osei G, Regmi P, Anderson V, Bosticardo M, Daub J, DiMaggio T, Kreuzburg S, Pala F, Pfister J, Treat J, Ulrick J, Karkanitsa M, Kalish H, Kuhns DB, Priel DL, Fink DL, Tsang JS, Sparks R, Uzel G, Waldman MA, Zerbe CS, Delmonte OM, Bergerson JRE, Das S, Freeman AF, Lionakis MS, Sadtler K, van Doremalen N, Munster V, Notarangelo LD, Holland SM, Ricotta EE. : Characterization of the antispike IgG immune response to COVID-19 vaccines in people with a wide variety of immunodeficiencies. Sci Adv 9(41): eadh3150, Oct 2023.

Li D, Sheppard SE, March ME, Battig MR, Surrey LF, Srinivasan AS, Matsuoka LS, Tian L, Wang F, Seiler C, Dayneka J, Borst AJ, Matos MC, Paulissen SM, Krishnamurthy G, Nriagu B, Sikder T, Casey M, Williams L, Rangu S, O'Connor N, Thomas A, Pinto E, Hou C, Nguyen K, Pellegrino da Silva R, Chehimi SN, Kao C, Biroc L, Britt AD, Queenan M, Reid JR, Napoli JA, Low DM, Vatsky S, Treat J, Smith CL, Cahill AM, Snyder KM, Adams DM, Dori Y, Hakonarson H.: Genomic profiling informs diagnoses and treatment in vascular anomalies. Nat Med 29(6): 1530-1539, Jun 2023.

Grenier JM, Borst AJ, Sheppard SE, Snyder KM, Li D, Surrey LF, Al-Ibraheemi A, Weber DR, Treat JR, Smith CL, Laje P, Dori Y, Adams DM, Acord M, Srinivasan AS. : Pathogenic variants in PIK3CA are associated with clinical phenotypes of kaposiform lymphangiomatosis, generalized lymphatic anomaly, and central conducting lymphatic anomaly. Pediatr Blood Cancer. 17(1): e30419, May 2023.

Sharma M, Leung D, Momenilandi M, Jones LCW, Pacillo L, James AE, Murrell JR, Delafontaine S, Maimaris J, Vaseghi-Shanjani M, Del Bel KL, Lu HY, Chua GT, Di Cesare S, Fornes O, Liu Z, Di Matteo G, Fu MP, Amodio D, Tam IYS, Chan GSW, Sharma AA, Dalmann J, van der Lee R, Blanchard-Rohner G, Lin S, Philippot Q, Richmond PA, Lee JJ, Matthews A, Seear M, Turvey AK, Philips RL, Brown-Whitehorn TF, Gray CJ, Izumi K, Treat JR, Wood KH, Lack J, Khleborodova A, Niemela JE, Yang X, Liang R, Kui L, Wong CSM, Poon GWK, Hoischen A, van der Made CI, Yang J, Chan KW, Rosa Duque JSD, Lee PPW, Ho MHK, Chung BHY, Le HTM, Yang W, Rohani P, Fouladvand A, Rokni-Zadeh H, Changi-Ashtiani M, Miryounesi M, Puel A, Shahrooei M, Finocchi A, Rossi P, Rivalta B, Cifaldi C, Novelli A, Passarelli C, Arasi S, Bullens D, Sauer K, Claeys T, Biggs CM, Morris EC, Rosenzweig SD, O'Shea JJ, Wasserman WW, Bedford HM, van Karnebeek CDM, Palma P, Burns SO, Meyts I, Casanova JL, Lyons JJ, Parvaneh N, Nguyen ATV, Cancrini C, Heimall J, Ahmed H, McKinnon ML, Lau YL, Béziat V, Turvey SE.: Human germline heterozygous gain-of-function STAT6 variants cause severe allergic disease. J Exp Med 220(5): e20221755, May 2023.

Bolli A, Nriagu B, Britt AD, Toole AD, Treat J, Srinivasan A, Sheppard SE. : Mosaic pathogenic variants in AKT3 cause capillary malformation and undergrowth. Am J Med Genet A. 191(5): 1442-1446, May 2023.

Larijani M, Zarowin D, Wohlschlaeger A, Perman MJ, Treat JR. : Atopic dermatitis-like graft-versus-host disease treated with dupilumab. Pediatr Dermatol 40(2): 320-322, Mar 2023.

Nriagu BN, Sanders VR, Bercovitch L, Snyder K, Cross EA, Treat JR, Sheppard SE.: Misdiagnosis of capillary malformations in darker skin phototypes. Pediatr Dermatol. 32(Suppl 2): 137-139, November 2021.

McKenzie PL, Rangu S, Treat JR, Castelo-Soccio L.: Experience using dupilumab for pediatric atopic dermatitis at a tertiary care c enter: Inadequate response and adverse events. Pediatr Dermatol. 38(5): 1178-1184, Sep 2021.

Bax CE, Khurana MC, Treat JR, Castelo-Soccio L, Rubin AI, McMahon PJ.: New-onset head and neck dermatitis in adolescent patients after dupilumab therapy for atopic dermatitis. Pediatr Dermatol. 38(2): 390-394, Mar 2021.

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Last updated: 12/16/2025
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