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James Treat, M.D.
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Professor of Clinical Pediatrics (General Pediatrics)
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Attending Dermatologist, Children's Hospital of Philadelphia
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Director of Education, Pediatric Dermatology, Children's Hospital of Philadelphia
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Associate Chair, IT, Department of Pediatrics, Children's Hospital of Philadelphia
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Associate Director, Pediatric Dermatology Fellowship, Children's Hospital of Philadelphia
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Department: Pediatrics
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Contact information
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University of Pennsylvania School of Medicine
2b Children's Hospital of Philadelphia
10 HUB 6581
3d 34th and Civic Center Blvd
Philadelphia, PA 19104
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2b Children's Hospital of Philadelphia
10 HUB 6581
3d 34th and Civic Center Blvd
Philadelphia, PA 19104
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Office: 215-590-2159
32 Fax: 215-590-4948
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32 Fax: 215-590-4948
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Education:
21 7 BA 3e (Biological Basis of Behavior, minor Anthropology ) c
33 University of Pennsylvania, 1997.
21 7 MD c
33 University of Pennsylvania, 2002.
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Permanent link21 7 BA 3e (Biological Basis of Behavior, minor Anthropology ) c
33 University of Pennsylvania, 1997.
21 7 MD c
33 University of Pennsylvania, 2002.
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32 Capillary Malformations (Port Wine Stains)
c Acne
19 Atopic Dermatitis
12 Birthmarks
23 Allergic Contact Dermatitis
3a Dermatologic manifestations of infectious diseases
16 Genodermatoses
18 Melanocytic Nevi
11 Molluscum
1c Pigmentary Anomalies
1d Pediatric Dermatology
c Warts
26 29
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Description of Clinical Expertise
1c Hemangiomas32 Capillary Malformations (Port Wine Stains)
c Acne
19 Atopic Dermatitis
12 Birthmarks
23 Allergic Contact Dermatitis
3a Dermatologic manifestations of infectious diseases
16 Genodermatoses
18 Melanocytic Nevi
11 Molluscum
1c Pigmentary Anomalies
1d Pediatric Dermatology
c Warts
26 29
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75 On A, Caussade MC, Britt A, Sheppard SE, Adams D, Hogrogian GS, Treat JR. 84 : Visualizing Genetics: An Investigation of Dermoscopy as a Tool for Genetic Variant Prediction in Capillary Malformations. 45 Pediatr Dermatol 43(1): 49-55, Jan-Feb 2026.
6f Lopes Almeida Gomes L, Mitchell D, Shah NJ, Greenfield M, Treat JR. 5a : Mycoplasma Rash With Eosinophilia and Systemic Symptoms: A Report of Two Cases. 4f Pediatr Dermatol online ahead of print, December 2025.
8d Britt A, Bolli A, Treat J, Cahill AM, Adams D, Ganguly A, Queenan M, Surrey L, Low D, Sheppard S. db : Somatic Genetic Testing Provides Diagnosis of Verrucous Venous Malformation in an Individual with Discrepant Radiology, Pathology, and Clinical Findings. J Vasc Anom 6(4), December 2025.
a6 Plumptre IR, Bitar RA, Grenier PO, Lee Y, Shah T, Hogrogian GS, Yan AC, Argade SM, Casey MA, Santos S, Treat JR, Liang MG. ac : Cutaneous adverse events associated with mitogen activated protein kinase inhibitors for the treatment of vascular anomalies: A dual-center retrospective study. 63 J Am Acad Dermatol 22(Online ahead of Print): S0190-9622(25)03446-2, 2025.
2c 1be Braun M, Frieden IJ, Siegel DH, George E, Hess CP, Fox CK, Chamlin SL, Drolet BA, Metry D, Pope E, Powell J, Holland K, Ulschmid C, Liang MG, Barry KK, Ho T, Cotter C, Baselga E, Bosquez D, Jain SN, Bui JK, Lara-Corrales I, Funk T, Small A, Baghoomian W, Yan AC, Treat JR, Hogrogian GS, Huang C, Haggstrom A, List M, McCuaig CC, Barrio V, Mancini AJ, Lawley LP, Grunnet-Satcher K, Horii KA, Newell B, Nopper A, Garzon MC, Scollan ME, Mathes EF. 9d : Multicenter Study of Long-Term Outcomes and Quality of Life in PHACE Syndrome after Age 10. J Pediatr 267(113907), Apr 2024.
237 Zendt M, Bustos Carrillo FA, Kelly S, Saturday T, DeGrange M, Ginigeme A, Wu L, Callier V, Ortega-Villa A, Faust M, Chang-Rabley E, Bugal K, Kenney H, Khil P, Youn JH, Osei G, Regmi P, Anderson V, Bosticardo M, Daub J, DiMaggio T, Kreuzburg S, Pala F, Pfister J, Treat J, Ulrick J, Karkanitsa M, Kalish H, Kuhns DB, Priel DL, Fink DL, Tsang JS, Sparks R, Uzel G, Waldman MA, Zerbe CS, Delmonte OM, Bergerson JRE, Das S, Freeman AF, Lionakis MS, Sadtler K, van Doremalen N, Munster V, Notarangelo LD, Holland SM, Ricotta EE. 8a : Characterization of the antispike IgG immune response to COVID-19 vaccines in people with a wide variety of immunodeficiencies. 3b Sci Adv 9(41): eadh3150, Oct 2023.
276 Li D, Sheppard SE, March ME, Battig MR, Surrey LF, Srinivasan AS, Matsuoka LS, Tian L, Wang F, Seiler C, Dayneka J, Borst AJ, Matos MC, Paulissen SM, Krishnamurthy G, Nriagu B, Sikder T, Casey M, Williams L, Rangu S, O'Connor N, Thomas A, Pinto E, Hou C, Nguyen K, Pellegrino da Silva R, Chehimi SN, Kao C, Biroc L, Britt AD, Queenan M, Reid JR, Napoli JA, Low DM, Vatsky S, Treat J, Smith CL, Cahill AM, Snyder KM, Adams DM, Dori Y, Hakonarson H.: Genomic profiling informs diagnoses and treatment in vascular anomalies. Nat Med 29(6): 1530-1539, Jun 2023.
ca Grenier JM, Borst AJ, Sheppard SE, Snyder KM, Li D, Surrey LF, Al-Ibraheemi A, Weber DR, Treat JR, Smith CL, Laje P, Dori Y, Adams DM, Acord M, Srinivasan AS. 100 : Pathogenic variants in PIK3CA are associated with clinical phenotypes of kaposiform lymphangiomatosis, generalized lymphatic anomaly, and central conducting lymphatic anomaly. Pediatr Blood Cancer. 17(1): e30419, May 2023.
76 Bolli A, Nriagu B, Britt AD, Toole AD, Treat J, Srinivasan A, Sheppard SE. 5b : Mosaic pathogenic variants in AKT3 cause capillary malformation and undergrowth. 47 Am J Med Genet A. 191(5): 1442-1446, May 2023.
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Selected Publications
12e Bitar RA, Servattalab SE, Liang MG, Spencer S, Ray A, Petty CR, Beqo BP, Hogrogian GS, Yan AC, Treat JR, Grenier PO.: Leg Length Discrepancy in Patients With Lower Extremity Cutis Marmorata Telangiectatica Congenita: A Multicenter Retrospective Study. 4a Pediatr Dermatol Online ahead of print, Feb 2026.75 On A, Caussade MC, Britt A, Sheppard SE, Adams D, Hogrogian GS, Treat JR. 84 : Visualizing Genetics: An Investigation of Dermoscopy as a Tool for Genetic Variant Prediction in Capillary Malformations. 45 Pediatr Dermatol 43(1): 49-55, Jan-Feb 2026.
6f Lopes Almeida Gomes L, Mitchell D, Shah NJ, Greenfield M, Treat JR. 5a : Mycoplasma Rash With Eosinophilia and Systemic Symptoms: A Report of Two Cases. 4f Pediatr Dermatol online ahead of print, December 2025.
8d Britt A, Bolli A, Treat J, Cahill AM, Adams D, Ganguly A, Queenan M, Surrey L, Low D, Sheppard S. db : Somatic Genetic Testing Provides Diagnosis of Verrucous Venous Malformation in an Individual with Discrepant Radiology, Pathology, and Clinical Findings. J Vasc Anom 6(4), December 2025.
a6 Plumptre IR, Bitar RA, Grenier PO, Lee Y, Shah T, Hogrogian GS, Yan AC, Argade SM, Casey MA, Santos S, Treat JR, Liang MG. ac : Cutaneous adverse events associated with mitogen activated protein kinase inhibitors for the treatment of vascular anomalies: A dual-center retrospective study. 63 J Am Acad Dermatol 22(Online ahead of Print): S0190-9622(25)03446-2, 2025.
2c 1be Braun M, Frieden IJ, Siegel DH, George E, Hess CP, Fox CK, Chamlin SL, Drolet BA, Metry D, Pope E, Powell J, Holland K, Ulschmid C, Liang MG, Barry KK, Ho T, Cotter C, Baselga E, Bosquez D, Jain SN, Bui JK, Lara-Corrales I, Funk T, Small A, Baghoomian W, Yan AC, Treat JR, Hogrogian GS, Huang C, Haggstrom A, List M, McCuaig CC, Barrio V, Mancini AJ, Lawley LP, Grunnet-Satcher K, Horii KA, Newell B, Nopper A, Garzon MC, Scollan ME, Mathes EF. 9d : Multicenter Study of Long-Term Outcomes and Quality of Life in PHACE Syndrome after Age 10. J Pediatr 267(113907), Apr 2024.
237 Zendt M, Bustos Carrillo FA, Kelly S, Saturday T, DeGrange M, Ginigeme A, Wu L, Callier V, Ortega-Villa A, Faust M, Chang-Rabley E, Bugal K, Kenney H, Khil P, Youn JH, Osei G, Regmi P, Anderson V, Bosticardo M, Daub J, DiMaggio T, Kreuzburg S, Pala F, Pfister J, Treat J, Ulrick J, Karkanitsa M, Kalish H, Kuhns DB, Priel DL, Fink DL, Tsang JS, Sparks R, Uzel G, Waldman MA, Zerbe CS, Delmonte OM, Bergerson JRE, Das S, Freeman AF, Lionakis MS, Sadtler K, van Doremalen N, Munster V, Notarangelo LD, Holland SM, Ricotta EE. 8a : Characterization of the antispike IgG immune response to COVID-19 vaccines in people with a wide variety of immunodeficiencies. 3b Sci Adv 9(41): eadh3150, Oct 2023.
276 Li D, Sheppard SE, March ME, Battig MR, Surrey LF, Srinivasan AS, Matsuoka LS, Tian L, Wang F, Seiler C, Dayneka J, Borst AJ, Matos MC, Paulissen SM, Krishnamurthy G, Nriagu B, Sikder T, Casey M, Williams L, Rangu S, O'Connor N, Thomas A, Pinto E, Hou C, Nguyen K, Pellegrino da Silva R, Chehimi SN, Kao C, Biroc L, Britt AD, Queenan M, Reid JR, Napoli JA, Low DM, Vatsky S, Treat J, Smith CL, Cahill AM, Snyder KM, Adams DM, Dori Y, Hakonarson H.: Genomic profiling informs diagnoses and treatment in vascular anomalies. Nat Med 29(6): 1530-1539, Jun 2023.
ca Grenier JM, Borst AJ, Sheppard SE, Snyder KM, Li D, Surrey LF, Al-Ibraheemi A, Weber DR, Treat JR, Smith CL, Laje P, Dori Y, Adams DM, Acord M, Srinivasan AS. 100 : Pathogenic variants in PIK3CA are associated with clinical phenotypes of kaposiform lymphangiomatosis, generalized lymphatic anomaly, and central conducting lymphatic anomaly. Pediatr Blood Cancer. 17(1): e30419, May 2023.
76 Bolli A, Nriagu B, Britt AD, Toole AD, Treat J, Srinivasan A, Sheppard SE. 5b : Mosaic pathogenic variants in AKT3 cause capillary malformation and undergrowth. 47 Am J Med Genet A. 191(5): 1442-1446, May 2023.
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