Yongping Wang, MD, PhD
Associate Professor of Clinical Pathology and Laboratory Medicine
Department: Pathology and Laboratory Medicine
Contact information
Cell Based Therapy Lab
Department of Pathology and Laboratory Medicine
5NW60 Main Building
Children's Hospital of Philadelphia
3401 Civic Center Blvd
Philadelphia, PA 19104
Department of Pathology and Laboratory Medicine
5NW60 Main Building
Children's Hospital of Philadelphia
3401 Civic Center Blvd
Philadelphia, PA 19104
Office: 215-590-4759
Lab: 215-590-2807
Lab: 215-590-2807
Email:
wangy2@chop.edu
wangy2@chop.edu
Education:
B.S. (Molecular Biophysics and Biochemistry; Economics)
Yale, 1995.
M.D, Ph.D. (Medicine; Pharmacology)
Dartmouth Medical School, 2003.
Permanent linkB.S. (Molecular Biophysics and Biochemistry; Economics)
Yale, 1995.
M.D, Ph.D. (Medicine; Pharmacology)
Dartmouth Medical School, 2003.
Description of Clinical Expertise
cGMP cellular therapy, stem cell, bone marrow transplant, hemoglobinopathy gene therapy, chimeric antigen receptor T cells (CARTs)Description of Research Expertise
RNAi, library screening, stem cell, erythropoiesisSelected Publications
Nora M. Gibson, Arwa Z. Al-Riyami, Alexis Peedin, Stephan Kadauke, Stephan Grupp, Timothy S. Olson, Yongping Wang: Challenging immunophenotyping of patients with sickle cell disease adversely affects gene therapy product manufacturing – case reports. International Society for Cell and Gene Therapy Annual Meeting, New Orleans, LA May 2025.Edo Schaefer, MD, Allyson Flower, MD, Janet Ayello, MS, MT, Yaya Chu, PhD, Carmella van De Ven, MS, Lauren Harrison, RN, MSN, Erin Morris, RN, Yongping Wang, MD, PhD, Shalini Shenoy, MD, MBBS, Dean Lee, MD, PHD, Rolla Abu-Arja, MD, Bryon D. Johnson, PhD, Tyce Kearl, MD, PhD, Michael R. Verneris, MD0, Julia Chu, MD, MPH, Christopher C. Dvorak, MD, Kenneth R. Cooke, MD, Julie Talano, MD, Nancy Bunin, MD, Mitchell S. Cairo, MD: Familial Donor Haploidentical Adenovirus (ADV)-specific Cytotoxic T-lymphocytes (CTLs) for Resistant Infections in Pediatric Patients Following Allogeneic Hematopoietic Stem Cell Transplantation (AlloHSCT): A Promising Approach. 12th Pediatic Transplantation & Cellular Therapy Consortium annual meeting, Louisville, KY May 2025.
Haydar Frangoul, MD, MS, Yongping Wang, MD, PhD, Meghann McManus,DO, MPH, Misty D Evans, DNP, APRN, CPNP-AC, Stephan Kadauke, MD, PhD, and Stephan A. Grupp, MD, PhD: Unmet Need in Stem Cell Mobilization for Gene Therapy in Patients with SickleCell Disease (SCD): A Multicenter Review. 41st American Society of Transplantation & Cellular Therapy annual meeting. Honolulu, HI. Feb 2025.
Nora M. Gibson, MD, MSCE, David F. Friedman, MD, Caitlin W. Elgarten, MD,MSCE, Abraham Haimed, MD, Eugene Khandros, MD, PhD, Elizabeth Worster, CRNP, Jonathan Bardahl, MD, Lisa Wray, MD, Yongping Wang, MD, PhD, Alexis A.Thompson, MD, MPH, Janet L. Kwiatkowski, MD, MSCE and Timothy S. Olson, MD,PhD ,: Post-Approval, Real-World Experience with Betibeglogene Autotemcel forTransfusion-Dependent Beta Thalassemia. 41st American Society of Transplantation & Cellular Therapy annual meeting. Honolulu, HI. Feb 2025.
Barz Leahy A, Cain L, DiNofia A, Fraietta J, Kadauke S, Li Y, Maude S, Myers R, Shinehouse L, Sparrow A, Varghese M, Wang L, Wang Y, Grupp SA: Cost-effective manufacture and promising initial efficacy of huCART19 cells manufactured using the CliniMACS Prodigy platform. 66th American Society of Hematology annual meeting, San Diego, CA Dec 2024.
Edo Schaefer, Allyson Flower, Janet Ayello, Yaya Chu, Carmella van De Ven, Lauren Harrison, Erin Morris, Yongping Wang, MD, Shalini Shenoy, Dean Lee, MD, Rolla Abu-Arja, Bryon D. Johnson, Michael R. Verneris, Christopher C. Dvorak, Julia Chu, Kenneth R. Cooke, Julie Talano, Nancy Bunin, Mitchell S. Cairo: The Safety of Familial Virus Specific Cytotoxic T-Lymphocytes for the Treatment of Refractory Viral Infection after Allogeneic Hematopoietic Stem Cell Transplantation, and Solid Organ Transplantation. 56th Congress of the International Society of Paediatric Oncology, Honolulu, HI Oct 2024.
Edo Schaefer, MD, Allyson Flower, MD, Janet Ayello, MS, MT, Yaya Chu, PhD, Carmella van De Ven, MS, Elizabeth Mintzer, Lauren Harrison, RN, MSN, Erin Morris, RN, Yongping Wang, MD, PhD, Shalini Shenoy, MD, MBBS, Dean Lee, MD, PHD, Rolla Abu-Arja, MD, Bryon D. Johnson, PhD, Michael R. Verneris, MD, Christopher C. Dvorak, MD, Julia Chu, MD, MPH, Kenneth R. Cooke, MD, Julie Talano, MD, Nancy Bunin, MD, Mitchell S. Cairo, MD: Treatment of Refractory Cytomegalovirus (CMV) Infections using CMV-specific Cytotoxic T-lymphocytes (CTLs) in Children, Adolescents and Young Adults (CAYA) Post Allogeneic Hematopoietic Stem Cell Transplantation (AlloHSCT) or Solid Organ Transplant (SOT). 11th Pediatric Transplantation and Cellular Therapy Consortium Annual meeting, Seattle, WA Apr 2024.
Edo Schaefer, MD Christine Vu, DO Allyson Flower, MD Janet Ayello, MS, MT(ASCP) Yaya Chu, PhD Carmella van de Ven, MA Elizabeth Mintzer Lauren Harrison, RN, MSN Erin Morris, RN, BSN Yongping Wang, MD, PhD Shalini Shenoy, MD Dean Anthony Lee, MD, PhD Rolla Abu-Arja, MD Bryon D Johnson, PhD Michael R. Verneris, MD Christopher C. Dvorak, MD Julia Chu, MD Kenneth R. Cooke, MD Julie A Talano, MD Nancy J. Bunin, MD Mitchell S. Cairo, MD: Adenoviral Cellular Therapy with Adenovirus (ADV)-specific Cytotoxic T-lymphocytes (CTLs) for Resistant Infections in Children, Adolescent, and Young Adult (CAYA) Patients Following Allogeneic Hematopoietic Stem Cell Transplantation (AlloHSCT): A Promising Approach. Transplantation and Cellular Therapy 30(2): S432, Feb 2024.
Nora M. Gibson, MD Caitlin W. Elgarten, MD, MSCE Joseph H. Oved, M.D. M.A. Lisa Wray, MD Jason L. Freedman, MD, MSCE Yongping Wang, MD, PhD Stephan Kadauke, MD, PhD Patricia Hankins, BSN, RN, CCRC Peter Nicholas Elizabeth Worster, CRNP Janet L. Kwiatkowski, MD, MSCE Stephan A. Grupp, MD, PhD Nancy J. Bunin, MD Timothy S. Olson, MD, PhD: Outcomes of Unrelated Partial T Cell Depleted Stem Cell Transplantation for Patients with Hemoglobinopathies. Transplantation and Cellular Therapy 30(2): S301, Feb 2024.
Caitlin W. Elgarten, MD, MSCE Stephanie Heidemann, MD Jason L. Freedman, MD, MSCE Stephan A. Grupp, MD, PhD Patricia Hankins, BSN, RN, CCRC Stephan Kadauke, MD, PhD Yimei Li, PhD Barbara McGlynn, BSN, RN Timothy S. Olson, MD, PhD Yongping Wang, MD, PhD Lisa Wray, MD Lei Wang, PhD Alix E. Seif, MD, MPH Nancy J. Bunin, MD: Pilot study of unrelated donor (URD) peripheral stem cell transplant (PSCT) with CD45RA depleted addback following TCRab/CD19 depletion in pediatric patients with hematologic malignancies. Transplantation and Cellular Therapy 30(2): S9, Feb 2024.