Sandhitsu Das, Ph.D.

Research Associate Professor of Neurology
Department: Neurology
Contact information
University of Pennsylvania
3700 Hamilton Walk, Fl 6
Philadelphia, PA 19104
3700 Hamilton Walk, Fl 6
Philadelphia, PA 19104
Office: (267) 408-3001
Fax: (215) 573-2701
Fax: (215) 573-2701
Education:
B. Tech (Electrical Engineering)
Indian Institute of Technology, 1997.
M. Tech (Digital Signal Processing)
Indian Institute of Technology, 1999.
Ph.D. (Neuroengineering)
University of Pennsylvania, 2006.
Permanent linkB. Tech (Electrical Engineering)
Indian Institute of Technology, 1997.
M. Tech (Digital Signal Processing)
Indian Institute of Technology, 1999.
Ph.D. (Neuroengineering)
University of Pennsylvania, 2006.
Selected Publications
Altmann A, Aksman LM, Oxtoby NP, Young AL; ADNI; Alexander DC, Barkhof F, Shoai M, Hardy J, Schott JM.: Towards cascading genetic risk in Alzheimer's disease. Brain 147: 2680-2690, Aug 2024.Dong M, Xie L, Das SR, Wang J, Wisse LEM, deFlores R, Wolk DA, Yushkevich PA.: Regional Deep Atrophy: a Self-Supervised Learning Method to Automatically Identify Regions Associated With Alzheimer's Disease Progression From Longitudinal MRI. Imaging Neuroscience Aug 2024.
Wisse LEM, Spotorno N, Rossi M, Grothe MJ, Mammana A, Tideman P, Baiardi S, Strandberg O, Ticca A, van Westen D, Mattsson-Carlgren N, Palmqvist S, Stomrud E, Parchi P, Hansson O; Alzheimer’s Disease Neuroimaging Initiative.: MRI Signature of α-Synuclein Pathology in Asymptomatic Stages and a Memory Clinic Population. JAMA Neurol Jul 2024.
Das SR, Ilesanmi A, Wolk DA, Gee JC.: Beyond Macrostructure: Is There a Role for Radiomics Analysis in Neuroimaging ? Magn Reson Med Sci 23: 367-376, Jul 2024.
Ravikumar S, Denning AE, Lim S, Chung E, Sadeghpour N, Ittyerah R, Wisse LEM, Das SR, Xie L, Robinson JL, Schuck T, Lee EB, Detre JA, Tisdall MD, Prabhakaran K, Mizsei G, de Onzono Martin MMI, Arroyo Jiménez MDM, Mũnoz M, Marcos Rabal MDP, Cebada Sánchez S, Delgado González JC, de la Rosa Prieto C, Irwin DJ, Wolk DA, Insausti R, Yushkevich PA.: Postmortem imaging reveals patterns of medial temporal lobe vulnerability to tau pathology in Alzheimer's disease. Nat Commun 15: 4803, Jun 2024.
Quesnel MJ, Labonté A, Picard C, Zetterberg H, Blennow K, Brinkmalm A, Villeneuve S, Poirier J; Alzheimer’s Disease Neuroimaging Initiative; PREVENT-AD Research Group.: Insulin-like growth factor binding protein-2 in at-risk adults and autopsy-confirmed Alzheimer brains. Brain 147: 1680-1695, May 2024.
Wang YT, Therriault J, Servaes S, Tissot C, Rahmouni N, Macedo AC, Fernandez-Arias J, Mathotaarachchi SS, Benedet AL, Stevenson J, Ashton NJ, Lussier FZ, Pascoal TA, Zetterberg H, Rajah MN, Blennow K, Gauthier S, Rosa-Neto P; Alzheimer’s Disease Neuroimaging Initiative.: Sex-specific modulation of amyloid-β on tau phosphorylation underlies faster tangle accumulation in females. Brain 147: 1497-1510, Apr 2024.
Xie L, Das SR, Wisse LEM, Ittyerah R, de Flores R, Shaw LM, Yushkevich PA, Wolk DA; Alzheimer’s Disease Neuroimaging Initiative.: Correction: Baseline structural MRI and plasma biomarkers predict longitudinal structural atrophy and cognitive decline in early Alzheimer's disease. Alzheimers Res Ther 16: 11, Jan 2024.
Brown C, Das S, Xie L, Nasrallah I, Detre J, Chen-Plotkin A, Shaw L, McMillan C, Yushkevich P, Wolk D.: Medial temporal lobe gray matter microstructure in preclinical Alzheimer's disease. Alzheimers Dement 2024.
Cousins KAQ, Phillips JS, Das SR, O'Brien K, Tropea TF, Chen-Plotkin A, Shaw LM, Nasrallah IM, Mechanic-Hamilton D, McMillan CT, Irwin DJ, Lee EB, Wolk DA.: Pathologic and cognitive correlates of plasma biomarkers in neurodegenerative disease. Alzheimers Dement 2024.