Emily Y. Chu, M.D., Ph.D.
Associate Professor of Dermatology at the Hospital of the University of Pennsylvania
Member, Abramson Cancer Center Melanoma and Cutaneous Malignancies Program
Co-director, Medical Oncodermatology Service, Hospital of the University of Pennsylvania
Director, Dermatopathology Resident Education, Perelman School of Medicine, University of Pennsylvania
Associate Director, Cutaneous Phenomics and Transcriptomics Core, Penn Skin Biology and Diseases Resource-Based Center (SBDRC)
Director, Dermatopathology Fellowship Program, Perelman School of Medicine, University of Pennsylvania
Department: Dermatology
Contact information
2 Maloney Building
3600 Spruce Street
Philadelphia, PA 19104
3600 Spruce Street
Philadelphia, PA 19104
Office: 215-662-6926
Fax: 215-662-7884
Fax: 215-662-7884
Education:
MS (Molecular, Cellular, and Developmental Biology)
Yale University, 1999.
BS (Molecular, Cellular, and Developmental Biology, with Distinction), summa cum laude)
Yale University , 1999.
PhD (Cell and Molecular Biology)
University of Pennsylvania , 2005.
MD (Cell and Molecular Biology)
University of Pennsylvania, 2006.
Permanent linkMS (Molecular, Cellular, and Developmental Biology)
Yale University, 1999.
BS (Molecular, Cellular, and Developmental Biology, with Distinction), summa cum laude)
Yale University , 1999.
PhD (Cell and Molecular Biology)
University of Pennsylvania , 2005.
MD (Cell and Molecular Biology)
University of Pennsylvania, 2006.
Description of Research Expertise
Molecular markers for melanomaInherited skin tumor syndromes
Cutaneous reactions to targeted and immunotherapies
Description of Clinical Expertise
DermatopathologyMelanoma
Inherited skin tumor syndromes
Cutaneous reactions to targeted and immunotherapies
Selected Publications
Nguyen, C.V., Gaddis, K.J., Stephens, M.R., Seykora, J.T., Chu, E.Y.: An intra-patient concordance study of mismatch repair protein immunohistochemical staining patterns in patients with Muir-Torre syndrome. JAMA Dermatology 156(6): 1-5, 2020.Ma, S.A,, O’Day, C.P., Dentchev, T., Takeshita, J., Ridky. T.W., Seykora, J.T., Chu, E.Y. : Expression of p15 in a spectrum of spitzoid melanocytic neoplasms. Journal of Cutaneous Pathology 46(5): 310-316, 2019.
Parekh, V., Sobanko, J., Miller, C.J., Karakousis, G., Xu, W., Letrero, R., Elenitsas, R., Amaravadi, R., Schuchter, L.M., Nathanson, K., Xu, X., Elder, D.E., Wilson, M.A., Chu, E.Y. : NRAS Q61R and BRAF G466A mutations in atypical melanocytic lesions arising in advanced melanoma patients treated with vemurafenib. Journal of Cutaneous Pathology 46(3): 190-194, 2019.
Wang, L.L., Patel, G., Chiesa Fuxench, Z.C., McGettigan, S., Schuchter, L.M., Mitchell, T.C., Ming, M.E., Chu, E.Y. : Timing of onset of adverse cutaneous reactions associated with programmed cell death-1 inhibitors. JAMA Dermatology 154(9): 1057-1061, 2018.
Xu, M., Horrell, J., Snitow, M., Cui, J., Gochnauer, H., Syrett, C., Kallish, S., Seykora, J.T., Liu, F., Gaillard, D., Katz, J., Kaestner, K., Levin, B., Mansfield, C., Douglas, J., Cowart, B., Tordoff, M., Liu, F., Zhu, X., Barlow, L., Rubin, A., McGrath, J., Morrisey, E., Chu, E.Y., & Millar, S.E. : WNT10A mutation causes ectodermal dysplasia by impairing progenitor cell proliferation and KLF4-mediated differentiation. Nature Communications 8(15397), 2017.
Marek Andrew J, Ming Michael E, Bartlett Edmund K, Karakousis Giorgos C, Chu Emily Y: Acral Lentiginous Histologic Subtype and Sentinel Lymph Node Positivity in Thin Melanoma. JAMA Dermatology 152(7): 836-7, Jul 2016.
Chu, E.Y., Wanat, K.A., Miller, C.J., Amaravadi, R.K., Fecher, L.A., Brose, M.S., McGettigan, S., Giles, L.R., Schuchter, L.M., Seykora, J.T., Rosenbach, M.: Diverse cutaneous side effects associated with BRAF inhibitor therapy: A clinicopathologic study. J Am Acad Dermatol 67(6): 1265-1272 2012.
Chu, E. Y., Freeman, A. F., Jing, H., Cowen, E. W., Davis, J., Su, H. C., Holland, S. M., Turner, M. L.: Cutaneous manifestations of DOCK8 deficiency syndrome. Arch Dermatol 148(1): 79-84, 2012.
Chu, E.Y., Hens, J., Andl, T., Kairo, A., Yamaguchi, T.P., Brisken, C., Glick, A., Wysolmerski, J.J., Millar, S.E.: Canonical WNT signaling promotes mammary placode development and is essential for initiation of mammary gland morphogenesis. Development 131(19): 4819-29, 2004.
Li, F., Ambrosini, G., Chu, E.Y., Plescia, J., Tognin, S., Marchisio, P.C., Altieri, D.C.: Control of apoptosis and mitotic spindle checkpoint by survivin. Nature 396(6711): 580-4, 1998.