Emily Y. Chu, M.D., Ph.D.

faculty photo
Assistant Professor of Dermatology at the Hospital of the University of Pennsylvania
Department: Dermatology

Contact information
2 Maloney Building
3600 Spruce Street
Philadelphia, PA 19104
Office: 215-662-6926
Fax: 215-662-7884
MS (Molecular, Cellular, and Developmental Biology)
Yale University, 1999.
BS (Molecular, Cellular, and Developmental Biology, with Distinction), summa cum laude)
Yale University , 1999.
PhD (Cell and Molecular Biology)
University of Pennsylvania , 2005.
MD (Cell and Molecular Biology)
University of Pennsylvania, 2006.
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Description of Research Expertise

Molecular markers for melanoma

Description of Clinical Expertise

Inherited skin tumor syndromes
Cutaneous reactions to targeted and immunotherapies

Selected Publications

Xu, M., Horrell, J., Snitow, M., Cui, J., Gochnauer, H., Syrett, C., Kallish, S., Seykora, J.T., Liu, F., Gaillard, D., Katz, J., Kaestner, K., Levin, B., Mansfield, C., Douglas, J., Cowart, B., Tordoff, M., Liu, F., Zhu, X., Barlow, L., Rubin, A., McGrath, J., Morrisey, E., Chu, E.Y., & Millar, S.E. : WNT10A mutation causes ectodermal dysplasia by impairing progenitor cell proliferation and KLF4-mediated differentiation. Nature Communications 8(15397), 2017.

Marek Andrew J, Ming Michael E, Bartlett Edmund K, Karakousis Giorgos C, Chu Emily Y: Acral Lentiginous Histologic Subtype and Sentinel Lymph Node Positivity in Thin Melanoma. JAMA Dermatology 152(7): 836-7, Jul 2016.

Lott Jason P, Elmore Joann G, Zhao Ge A, Knezevich Stevan R, Frederick Paul D, Reisch Lisa M, Chu Emily Y, Cook Martin G, Duncan Lyn M, Elenitsas Rosalie, Gerami Pedram, Landman Gilles, Lowe Lori, Messina Jane L, Mihm Martin C, van den Oord Joost J, Rabkin Michael S, Schmidt Birgitta, Shea Christopher R, Yun Sook Jung, Xu George X, Piepkorn Michael W, Elder David E, Barnhill Raymond L: Evaluation of the Melanocytic Pathology Assessment Tool and Hierarchy for Diagnosis (MPATH-Dx) classification scheme for diagnosis of cutaneous melanocytic neoplasms: Results from the International Melanoma Pathology Study Group. Journal of the American Academy of Dermatology 75(2): 356-63, Aug 2016.

Sargen, M.R., Merrill, S.L., Chu, E.Y., Nathanson, K.L.: CDKN2A mutations with p14 loss predisposing to multiple nerve sheath tumours, melanoma, dysplastic nevi, and internal malignancies: A case series and review of the literature. The British Journal of Dermatology 175(4): 785-9 Feb 2016.

Chu, E.Y., Wanat, K.A., Miller, C.J., Amaravadi, R.K., Fecher, L.A., Brose, M.S., McGettigan, S., Giles, L.R., Schuchter, L.M., Seykora, J.T., Rosenbach, M.: Diverse cutaneous side effects associated with BRAF inhibitor therapy: A clinicopathologic study. J Am Acad Dermatol 67(6): 1265-1272 2012.

Chu, E. Y., Freeman, A. F., Jing, H., Cowen, E. W., Davis, J., Su, H. C., Holland, S. M., Turner, M. L.: Cutaneous manifestations of DOCK8 deficiency syndrome. Arch Dermatol 148(1): 79-84, 2012.

Lang, D.,Lu, M.M., Huang, L., Engleka, K.A., Zhang, M., Chu, E.Y., Lipner, S., Skoultchi, A., Millar, S.E., Epstein, J.A.: Pax3 functions at a nodal point in melanocyte stem cell differentiation. Nature 433(7028): 884-7, 2005.

Chu, E.Y., Hens, J., Andl, T., Kairo, A., Yamaguchi, T.P., Brisken, C., Glick, A., Wysolmerski, J.J., Millar, S.E.: Canonical WNT signaling promotes mammary placode development and is essential for initiation of mammary gland morphogenesis. Development 131(19): 4819-29, 2004.

Li, F., Ambrosini, G., Chu, E.Y., Plescia, J., Tognin, S., Marchisio, P.C., Altieri, D.C.: Control of apoptosis and mitotic spindle checkpoint by survivin. Nature 396(6711): 580-4, 1998.

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Last updated: 05/28/2019
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