Leslie Raffini, M.D., M.S.C.E.
Professor of Pediatrics (Hematology) at the Children's Hospital of Philadelphia
Director, Hemostasis and Thrombosis Center, Children's Hospital of Philadelphia, University of Pennsylvania
Department: Pediatrics
Contact information
Children's Hospital of Philadelphia
Division of Hematology
The HUB for Clinical Collaboration
3500 Civic Center Blvd
13th Floor
Philadelphia, PA 19104
Division of Hematology
The HUB for Clinical Collaboration
3500 Civic Center Blvd
13th Floor
Philadelphia, PA 19104
Office: 267 426-5029
Email:
raffini@email.chop.edu
raffini@email.chop.edu
Education:
B.S. (Molecular Biology)
University of Wisconsin, 1991.
M.D.
University of Wisconsin, 1996.
M.S.C.E (Clinical Epidemiology)
University of Pennsylvania, 2005.
Permanent linkB.S. (Molecular Biology)
University of Wisconsin, 1991.
M.D.
University of Wisconsin, 1996.
M.S.C.E (Clinical Epidemiology)
University of Pennsylvania, 2005.
Description of Research Expertise
Risk Factors for Thromboembolic Events in ChildrenDescription of Clinical Expertise
Diagnosis and Management of Thromboembolic Events in ChildrenDescription of Other Expertise
Diagnosis and Management of Bleeding Disorders in ChildrenSelected Publications
Zantek N., Steiner M., Teruya J., Baumann-Kreuziger L., Raffini L., Muszynski J., Alexander P., Watt K.: Recommendations on monitoring and replacement of antithrombin, fibrinogen and von Willebrand factor in pediatric patients on ECMO from the Pediatric ECMO Anticoagulation Collaborative (PEACE) Consensus Conference Series. Pediatr Crit Care Med 25(7): e35-43, 2024.Whitworth H., Weber M., Faustino V., Raffini L., Witmer C.: Pediatric venous thromboembolism associated with midline and peripherally inserted central catheters. ISTH Annual Meeting Bangkok Thailand 2024.
Bhatt M., Kulkarni K., Singh G., Raffini L., Dhaliwal M., Chan A.: A pilot feasibility and safety multicenter trial of administering weight adjusted fixed dose of low molecular weight heparin (enoxaparin) to neonates and children with thrombosis (FIXET). ISTH Annual Meeting Bangkok Thailand 2024.
Prudente T., Mesquita Camelo R., Guimaraes R., Roberti M.: Emicizumab prophylaxis in people with hemophilia A and inhibitors: a systematic review and meta-analysis. Sao Paulo Med J. e2023102, 2024.
Faustino V., Kandil S. Leroue M., Sochet A., Kong M., Cholette J., Nellis M., Pinto M., Chegondi M., Ramirez M., Schrieber H., Kerris E., Glau C., Kolmar A., Muisyo T., Sharathkumar A., Polikoff L., Silva C., Ehrlich L., Navarro O., Spinella P., Raffini L., Taylor S., McPartland T., Shabanova V. for the Crete Studies Investigators: Protocol for the Catheter-Related Early Thromboprophylaxis with Enoxaparin (CRETE) Studies. Pediatr Crit Care Med Page: in press, 2024.
Alexander P., Bembrea M., Cashen K, Cheifetz I., Dalton H., Himebauch A., Karam Ol, Moynihan K., Nellis M., Ozment C., Raman L, Rintoul N., Said A., Saini A. Steiner M., Thiagarajan R., Watt K., Willems A., Zantek N., Barbaro R., Steffen K., Vogel A., Almond C., Anders M., Brandao L., Chandler W., Delaney M., DiGeronimo R., Emani S., Gadepalli S., Garcia A., Haileselassie B., Hyslop R., Kneyber M., Bauman Kreuziger L, Le J., Loftis L, McMichael A., Monagle P., Nicol K., Paden M., Patregnani J., Priest J., Raffini L., Ryerson L., Sloan S., Teruya J., Yates A., Gehred A., Lyman El, Muszynski J. : Executive Summary: Pediatric ECMO Anticoagualtion Collaborative (PEACE) Consensus Conference. Pediatr Crit Care Med 25(7): 643-75, 2024.
Wiggins M., Chan A., Goldenburg N., Raffini L., Vanderplum C., Van Ommen H., Monagle P.: Accidental apixaban overdose in children: case report and proposed plan for management: A brief communication from the pediatric and perinatal SSC of ISTH. Res Pract Thromb Haemost 8(1): 102312, 2024.
Whitworth H., Wagner K., Zelenski A., DiCocco E., Davies A., Jordan R., Higginbotham M., Bailey C., Raffini L.: Computable phENotype To Identify Pulmonary Embolism in chilDrEn: The CENTIPEDE study. ISTH Annual Meeting Bangkok, Thailand 2024.
Rastogi R., Okunwono O., Faerber J., Mavroudis C., Whitworth H., Giglia T., Witmer C., Raffini L., O’Byrne M. : Incidence, management and outcomes of pediatric pulmonary embolism in the United States: An observational study using data from the Pediatric Health Information System Database. JACC Adv. 3(4): 100895, 2024.
Dain A.S., Whitworth H., Raffini L: Letter to the editor in response to “Coagulation abnormalities and clinical complications in children with SARs-CoV-2: A systematic review of 48,322 patients” J Pediatr Hematol Oncol 45(1): 44-45, 2023.