Leslie Raffini, M.D., M.S.C.E.

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Professor of Pediatrics (Hematology) at the Children's Hospital of Philadelphia
Director, Hemostasis and Thrombosis Center, Children's Hospital of Philadelphia, University of Pennsylvania
Department: Pediatrics

Contact information
Children's Hospital of Philadelphia
Division of Hematology
3501 Civic Center Blvd
CTRB 11th Floor
Philadelphia, PA 19104
Office: 267 426-5029
B.S. (Molecular Biology)
University of Wisconsin, 1991.
University of Wisconsin, 1996.
M.S.C.E (Clinical Epidemiology)
University of Pennsylvania, 2005.
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Description of Research Expertise

Risk Factors for Thromboembolic Events in Children

Description of Clinical Expertise

Diagnosis and Management of Thromboembolic Events in Children

Description of Other Expertise

Diagnosis and Management of Bleeding Disorders in Children

Selected Publications

Dain A.S., Whitworth H., Raffini L: Letter to the editor in response to “Coagulation abnormalities and clinical complications in children with SARs-CoV-2: A systematic review of 48,322 patients” J Pediatr Hematol Oncol 45(1): 44-45, 2023.

Whitworth H., Amankwah E., Betensky M., Castellucci L., Cuker A., Goldenberg N., Male C., Rinzler E., Zia A., Raffini L: Updated guidance for efficacy and safety outcomes for clinical trials in venous thromboembolism in children: Communication from the ISTH SSC Subcommittee on Pediatric and Neonatal Thrombosis and Hemostasis. J Thromb Haemost epub ahead of print 2023.

Barnes G., Ageno W., Castellucci L., Chiasakul T., Eslick R., Gailani D., Raffini L., Rzende S., Weitz J., Cuker A. : Recommendation on the nomenclature for oral anticoagulants: Updated guidance from the SSC of the ISTH. J Thromb Haemost epub ahead of print 2023.

Monagle P., Male C., Raffini L: The value of the old and the new; a commentary regarding the need to update the 2018 ASH Guidelines for the management of pediatric venous thromboembolism. Blood Adv epub ahead of print 2023.

Whitworth, H., Clark H., Hubbard R., Witmer C., Leonard C., Raffini L.: High rate of recurrent venous thromboembolism in children and adolescents with unprovoked venous thromboembolism. J Thromb Haem 21(1): 47-56, 2023.

Whitworth H., Beslow L., Hubbard R., Leonard C., Scobell R., Witmer C., Raffini L.: Outcomes in infants with unprovoked venous thromboembolis. Res Pract Thrombosis Haemost in press, 2023.

Ragni M., Young G., Batsuli G., Bisson E., Carpenter S., Croteau S., Cuker A., Curtis R., Denne M., Ewenstein B., Federizo A., Frick N., Funkhouser K., George L., Hoots K., Jobe S., Krava E., Landmead C., Lewis R., Lopez J., Malec L., Mann Z., Neely E., Neufeld E., Pierce G., Pipe S., Pitler L., Raffini L., Schnur L, Shavit J. : Building the foundation for a community-generated national research blueprint for inherited bleeding disorders. Facilitating research through infrastructure, workforce, and resources and funding Expert Rev Hematologist 16: 107-27, 2023.

O’Brien S., Stanek J., Witmer C. Raffini L.: The continued rise of venous thromboembolism across U.S. Children’s Hospitals. Pediatrics in press, 2022.

Barnes G., Burnett A., Allen A., Ansell J., Blumenstein M., Clark N., Crowther M., Dager W. Deitelzweig S., Ellsworth S., Garcia D., Kaatz S., Raffini L., Rajasekhar A., VanBeek A., Minichiello T.: Thromboembolic prevention and anticoagulant therapy during the COVID-19 pandemic: updated clinical guidance from the anticoagulation forum. J Thromb Thrombolysis 54(2): 197-22, 2022.

Whitworth H., Raffini L: Practical considerations for use of direct oral anticoagulants in children. Front Pediatr 10: e860369, 2022.

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Last updated: 06/13/2023
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