Jennifer J.D. Morrissette, Ph.D.
Professor of Clinical Pathology and Laboratory Medicine
Scientific Director, Cancer Cytogenetics, Hospital of the University of Pennsylvania, Perelman School of Medicine, Department of Pathology and Laboratory Medicine
Clinical Director, Center for Personalized Diagnostics, Hospital of the University of Pennsylvania, Department of Pathology of Laboratory Medicine
Interim Director, Center for Personalized Diagnostics, University of Pennsylvania
Department: Pathology and Laboratory Medicine
Contact information
Department of Pathology and Laboratory Medicine
3020 Market Street, Suite 220
Philadelphia, PA 19104
3020 Market Street, Suite 220
Philadelphia, PA 19104
Office: 215-615-2387
Fax: 215-898-9817
Fax: 215-898-9817
Publications
Links
Search PubMed for articles
Website describing the Center for Personalized Diagnostics and our role in the detection of mutations in hematological and solid tumors.
Search PubMed for articles
Website describing the Center for Personalized Diagnostics and our role in the detection of mutations in hematological and solid tumors.
Education:
B.S. (Molecular Biology)
State University of New York at Buffalo, 1986.
Ph.D. (Molecular Genetics)
State University of New York at Buffalo, 1992.
Permanent linkB.S. (Molecular Biology)
State University of New York at Buffalo, 1986.
Ph.D. (Molecular Genetics)
State University of New York at Buffalo, 1992.
Selected Publications
Matsumoto Y, Singh O, Garcia J, Abdullaev Z, Freeburg NF, Yu F, Akbari H, Baik K, Guo J, Shih NNC, Toorens E, Ganguly T, Ballinger D, O'Rourke DM, Mohan S, Morrissette JJD, Silverbush D, Aldape K, Davatzikos C, Nasrallah MP.: Intra-tumoral Preservation of the Stem-like Malignant Cell Proportion in Glioblastoma, Prognostic Impact, and its Radiomethylomic Signatures. Neuro Oncol. July 2025.Pawar AS, Somers P, Alex A, Grana J, Feist VK, George SS, Jalnapurkar SS, Antony C, Verner R, White-Brown SK, Khera M, Mendoza-Figueroa MS, Liu KF, Morrissette JJD, Gurbuxani S, Paralkar VR.: Leukemia mutated proteins PHF6 and PHIP form a chromatin complex that represses acute myeloid leukemia stemness. Genes Dev. July 2025.
Sahasrabuddhe AA, Chen X, Ma K, Wu R, Liang HC, Kapoor R, Chhipa RR, Onder O, McFetridge C, Van Arnam JS, Zhang X, Morrissette JJD, Pillai V, Li MM, Szankasi P, Basrur V, Conlon KP, Raabe TD, Bailey NG, Hogaboam CM, Rottapel R, Kim J, López C, Schlesner M, Siebert R, Dreval K, Morin RD, Moro L, Pagano M, Staudt LM, Lim MS, Elenitoba-Johnson KSJ.: The FBXO45-GEF-H1 axis controls germinal center formation and B-cell lymphomagenesis. Cancer Discov. 15: 838-861, April 2025.
Sande CM, Chen S, Mitchell DV, Lin P, Abraham DM, Cheng JM, Gebhard T, Deolikar RJ, Freeman C, Zhou M, Kumar S, Bowman M, Bowman RL, Zheng S, Munkhbileg B, Chen Q, Stanley NL, Guo K, Lapite A, Hausler R, Taylor DM, Corines J, Morrissette JJ, Lieberman DB, Yang G, Shestova O, Gill S, Zheng J, Smith-Simmer K, Banaszak LG, Shoger KN, Reinig EF, Peterson M, Nicholas P, Walne AJ, Dokal I, Rosenheck JP, Oetjen KA, Link DC, Gelman AE, Reilly CR, Dutta R, Lindsley RC, Brundige KJ, Agarwal S, Bertuch AA, Churpek JE, Tague LK, Johnson FB, Olson TS, Babushok DV.: ATM-dependent DNA damage response constrains cell growth and drives clonal hematopoiesis in telomere biology disorders. J Clin Invest 135, April 2025.
Chow RD, Velu P, Deihimi S, Belman JP, Youn A, Shah N, Luger SM, Carroll MP, Morrissette JJ, Bowman RL.: Persistent post-remission clonal hematopoiesis shapes the relapse trajectories of acute myeloid leukemia. Blood Adv. 9: 1888-1899, April 2025.
Landsburg DJ, Morrissette JJD, Nasta SD, Barta SK, Schuster SJ, Chong EA, Svoboda J, Barlev A, Bagg A, Priore SF.: Genomic Features of Newly Diagnosed Large B-cell Lymphoma with or without Subsequent Disease Progression. Cancer Res Commun. 4: 2947-2954, Nov. 2024.
Ni V, Nasta SD, Barta SK, Schuster SJ, Chong EA, Svoboda J, Morrissette JJD, Barlev A, Bagg A, Priore SF, Landsburg DJ.: Identification of a clinicopathologic prognostic index for newly diagnosed large B cell lymphoma patients treated with R-CHOP. Haematologica Nov 2024.
Balciuniene J, Ning Y, Lazarus HM, Aikawa V, Sherpa S, Zhang Y, Morrissette JJD.: Cancer cytogenetics in a genomics world: Wedding the old with the new. Blood Rev. July 2024.
Laczko D, Poveda-Rogers C, Matthews AH, Snaith O, Luger S, Bagg A, Caponetti GC, Morrissette JJD, Yang G.: RAD21 mutations in acute myeloid leukemia. Leuk Lymphoma. Jul 2024.
Marmarelis ME, Scholes DG, McGrath CM, Priore SF, Roth JJ, Feldman M, Morrissette JJD, Litzky L, Deshpande C, Thompson JC, Doucette A, Gabriel PE, Sun L, Singh AP, Cohen RB, Langer CJ, Carpenter EL, Aggarwal C.: Brief Report: Impact of Reflex Testing on Tissue-Based Molecular Genotyping in Patients With Advanced Non-Squamous Non-Small Cell Lung Cancer. Clin Lung Cancer. May 2024.