Jennifer J.D. Morrissette, Ph.D.
Professor of Clinical Pathology and Laboratory Medicine
Scientific Director, Cancer Cytogenetics, Hospital of the University of Pennsylvania, Perelman School of Medicine, Department of Pathology and Laboratory Medicine
Clinical Director, Center for Personalized Diagnostics, Hospital of the University of Pennsylvania, Department of Pathology of Laboratory Medicine
Laboratory Director, CytoGenomics, Hospital of the University of Pennsylvania, Department of Pathology and Laboratory Medicine
Interim Director, Center for Personalized Diagnostics, University of Pennsylvania
Department: Pathology and Laboratory Medicine
Contact information
Department of Pathology and Laboratory Medicine
3020 Market Street, Suite 220
Philadelphia, PA 19104
3020 Market Street, Suite 220
Philadelphia, PA 19104
Office: 215-615-2387
Fax: 215-898-9817
Fax: 215-898-9817
Publications
Links
Search PubMed for articles
Website describing the Center for Personalized Diagnostics and our role in the detection of mutations in hematological and solid tumors.
Search PubMed for articles
Website describing the Center for Personalized Diagnostics and our role in the detection of mutations in hematological and solid tumors.
Education:
B.S. (Molecular Biology)
State University of New York at Buffalo, 1986.
Ph.D. (Molecular Genetics)
State University of New York at Buffalo, 1992.
Permanent linkB.S. (Molecular Biology)
State University of New York at Buffalo, 1986.
Ph.D. (Molecular Genetics)
State University of New York at Buffalo, 1992.
Selected Publications
Chow RD, Velu P, Deihimi S, Belman JP, Youn A, Shah N, Luger SM, Carroll MP, Morrissette JJ, Bowman RL.: Persistent post-remission clonal hematopoiesis shapes the relapse trajectories of acute myeloid leukemia. Blood Adv. Feb 2025.Sahasrabuddhe AA, Chen X, Ma K, Wu R, Liang HC, Kapoor R, Chhipa RR, Onder O, McFetridge C, Van Arnam JS, Zhang X, Morrissette JJD, Pillai V, Li MM, Szankasi P, Basrur V, Conlon KP, Raabe TD, Bailey NG, Hogaboam CM, Rottapel R, Kim J, López C, Schlesner M, Siebert R, Dreval K, Morin RD, Moro L, Pagano M, Staudt LM, Lim MS, Elenitoba-Johnson KSJ.: The FBXO45-GEF-H1 axis controls germinal center formation and B-cell lymphomagenesis. Cancer Discov. Jan 2025.
Pawar AS, Somers P, Alex A, George SS, Antony C, Verner R, White-Brown SK, Khera M, Mendoza-Figueroa MS, Liu KF, Morrissette JJD, Paralkar VR.: Leukemia-mutated proteins PHF6 and PHIP form a chromatin complex that represses acute myeloid leukemia stemness. bioRxiv [Preprint] Dec 2024.
Landsburg DJ, Morrissette JJD, Nasta SD, Barta SK, Schuster SJ, Chong EA, Svoboda J, Barlev A, Bagg A, Priore SF.: Genomic Features of Newly Diagnosed Large B-cell Lymphoma with or without Subsequent Disease Progression. Cancer Res Commun. 4: 2947-2954, Nov. 2024.
Ni V, Nasta SD, Barta SK, Schuster SJ, Chong EA, Svoboda J, Morrissette JJD, Barlev A, Bagg A, Priore SF, Landsburg DJ.: Identification of a clinicopathologic prognostic index for newly diagnosed large B cell lymphoma patients treated with R-CHOP. Haematologica Nov 2024.
Chow RD, Velu P, Deihimi S, Belman J, Youn A, Shah N, Luger SM, Carroll MP, Morrissette J, Bowman RL.: Early drivers of clonal hematopoiesis shape the evolutionary trajectories of de novo acute myeloid leukemia. medRxiv [Preprint]. Sept 2024.
Balciuniene J, Ning Y, Lazarus HM, Aikawa V, Sherpa S, Zhang Y, Morrissette JJD.: Cancer cytogenetics in a genomics world: Wedding the old with the new. Blood Rev. July 2024.
Laczko D, Poveda-Rogers C, Matthews AH, Snaith O, Luger S, Bagg A, Caponetti GC, Morrissette JJD, Yang G.: RAD21 mutations in acute myeloid leukemia. Leuk Lymphoma. Jul 2024.
Marmarelis ME, Scholes DG, McGrath CM, Priore SF, Roth JJ, Feldman M, Morrissette JJD, Litzky L, Deshpande C, Thompson JC, Doucette A, Gabriel PE, Sun L, Singh AP, Cohen RB, Langer CJ, Carpenter EL, Aggarwal C.: Brief Report: Impact of Reflex Testing on Tissue-Based Molecular Genotyping in Patients With Advanced Non-Squamous Non-Small Cell Lung Cancer. Clin Lung Cancer. May 2024.
Ghilardi G, Fraietta JA, Gerson JN, Van Deerlin VM, Morrissette JJD, Caponetti GC, Paruzzo L, Harris JC, Chong EA, Susanibar Adaniya SP, Svoboda J, Nasta SD, Ugwuanyi OH, Landsburg DJ, Fardella E, Waxman AJ, Chong ER, Patel V, Pajarillo R, Kulikovskaya I, Lieberman DB, Cohen AD, Levine BL, Stadtmauer EA, Frey NV, Vogl DT, Hexner EO, Barta SK, Porter DL, Garfall AL, Schuster SJ, June CH, Ruella M.: T-cell Lymphoma and Secondary Primary Malignancy Risk After Commercial CAR T-cell Therapy. Nat Med. 30, April 2024.