Jennifer J.D. Morrissette, Ph.D.
Associate Professor of Clinical Pathology and Laboratory Medicine
Scientific Director, Cancer Cytogenetics, Hospital of the University of Pennsylvania, Perelman School of Medicine, Department of Pathology and Laboratory Medicine
Clinical Director, Center for Personalized Diagnostics, Hospital of the University of Pennsylvania, Department of Pathology of Laboratory Medicine
Laboratory Director, CytoGenomics, Hospital of the University of Pennsylvania, Department of Pathology and Laboratory Medicine
Interim Director, Center for Personalized Diagnostics, University of Pennsylvania
Department: Pathology and Laboratory Medicine
Contact information
Department of Pathology and Laboratory Medicine
3020 Market Street, Suite 220
Philadelphia, PA 19104
3020 Market Street, Suite 220
Philadelphia, PA 19104
Office: 215-615-2387
Fax: 215-898-9817
Fax: 215-898-9817
Publications
Links
Search PubMed for articles
Website describing the Center for Personalized Diagnostics and our role in the detection of mutations in hematological and solid tumors.
Search PubMed for articles
Website describing the Center for Personalized Diagnostics and our role in the detection of mutations in hematological and solid tumors.
Education:
B.S. (Molecular Biology)
State University of New York at Buffalo, 1986.
Ph.D. (Molecular Genetics)
State University of New York at Buffalo, 1992.
Permanent linkB.S. (Molecular Biology)
State University of New York at Buffalo, 1986.
Ph.D. (Molecular Genetics)
State University of New York at Buffalo, 1992.
Selected Publications
Ghilardi G, Fraietta JA, Gerson JN, Van Deerlin VM, Morrissette JJD, Caponetti GC, Paruzzo L, Harris JC, Chong EA, Susanibar Adaniya SP, Svoboda J, Nasta SD, Ugwuanyi OH, Landsburg DJ, Fardella E, Waxman AJ, Chong ER, Patel V, Pajarillo R, Kulikovskaya I, Lieberman DB, Cohen AD, Levine BL, Stadtmauer EA, Frey NV, Vogl DT, Hexner EO, Barta SK, Porter DL, Garfall AL, Schuster SJ, June CH, Ruella M.: T-cell Lymphoma and Secondary Primary Malignancy Risk After Commercial CAR T-cell Therapy. Nat Med. Jan. 2024.Landsburg DJ, Morrissette JJ, Nasta SD, Barta SK, Schuster SJ, Svoboda J, Chong EA, Bagg A.: TP53 mutations predict for poor outcomes in patients with newly diagnosed aggressive B-cell lymphomas in the current era. Blood Adv. 7: 7243-7253, Dec 2023.
Sande CM, Chen S, Mitchell DV, Lin P, Deolikar RJ, Freeman C, Zhou M, Zheng S, Munkhbileg B, Stanley NL, Guo K, Hausler R, Taylor D, Corines J, Morrissette JJD, Lieberman DB, Yang G, Nicholas P, Dokal I, Rosenheck J, Churpek J, Johnson FB, Olson TS, Babushok DV: DNA Damage Response Constrains Cell Growth and Drives Clonal Hematopoiesis in Telomere Biology Disorders. American Society of Haematology (ASH) Annual Meeting Dec. 2023 Notes: ASH abstract with trainees.
Frost BF, Morrissette JJD, Shuster SJ, Nasta SD, Svoboda J, Barta SK, Elise A. Chong3, Ruella M, Bagg A, Landsburg DJ: Impact of Genetic Mutations on Survival Following Receipt of commercial CART19 for Patients Diagnosed with Aggressive B Cell Lymphoma American Society of Haematology (ASH) Annual meeting Dec. 2023 Notes: ASH annual meeting abstract with student.
Bhansali1 RS, Wang X, Mattfield V, Clark D, Morrissette JJD, Babushok D, Carroll M, Bruno XJ: Somatic Mutation Screening in Adult Patients with Myeloid Malignancies Provides Insights into Likely Germline Variants. American Society of Haematology (ASH) Annual meeting Dec. 2023 Notes: ASH abstract with Student.
Poveda-Rogers C, Ni V, Corines J, Morrissette JJD, Yang G : Features of Loss-of-Function SYK-Mutated Advanced Melanoma. Association for Molecular Pathology (AMP) annual meeting Nov. 2023 Notes: abstract with students.
Poveda-Rogers C, Ni V, Corines J, Morrissette JJD, Yang G : CDH1 is an Uncommon but Recurrent Tumor Suppressor Gene Mutated in Advanced Prostate Cancer Association for Molecular Pathology (AMP) annual meeting Nov. 2023 Notes: Abstract with students.
Aisner DL, Gocke CD, Jones D, Limson M, Morrissette J, Segal JP.: The Genomics Organization for Academic Laboratories (GOAL): A vision for a genomics future for academic pathology. Acad Pathol. 10, Aug 2023.
Meredith DM, Cooley LD, Dubuc A, Morrissette J, Sussman RT, Nasrallah MP, Rathbun P, Yap KL, Wadhwani N, Bao L, Wolff DJ, Ida C, Sukhanova M, Horbinski C, Jennings LJ, Farooqi M, Gener M, Ginn K, Kam KL, Sasaki K, Kanagal-Shamanna R, Alexandrescu S, Brat D, Lu X.: ROS1 alterations as a potential driver of gliomas in infant, pediatric, and adult patients. Mod Pathol. 36(11): 100294, July 2023 Notes: doi: 10.1016/j.modpat.2023.100294. Epub 2023 Jul 31. Meta-Analysis.
Yoon JY, Roth JJ, Rushton CA, Morrissette JJD, Nathanson KL, Cohen RB, Rosenbaum JN.: Homologous recombination pathway gene variants identified by tumor-only sequencing assays in lung carcinoma patients. Transl Lung Cancer Res. 12: 1236-1244, June 2023.