Emily A Largent JD, PhD, RN

Emanuel and Robert Hart Associate Professor in Bioethics
Senior Fellow, Leonard Davis Institute of Health Economics, University of Pennsylvania
Division Chief, Medical Ethics, Department of Medical Ethics & Health Policy
Department: Medical Ethics and Health Policy
Contact information
1403 Blockley Hall
423 Guardian Drive
Philadelphia, PA 19104
423 Guardian Drive
Philadelphia, PA 19104
Education:
BS
Georgetown University, 2004.
BS (Nursing)
University of Pennsylvania, 2006.
JD
Harvard Law School, 2016.
PhD
Harvard University, 2016.
Permanent linkBS
Georgetown University, 2004.
BS (Nursing)
University of Pennsylvania, 2006.
JD
Harvard Law School, 2016.
PhD
Harvard University, 2016.
Selected Publications
Langbaum JB, Bradbury AR, Egleston BL, McCarty Wood E, Langlois CM, Largent E, Harkins K, Erickson CM, Stites S, Oyen E, Riviere ME, Liu F, Graf A, Kim S, Grill JD, Reiman EM, Tariot PN, Roberts JS, Karlawish J. : Impact of learning APOE genotype on cognitively unimpaired adults: The Alzheimer’s Prevention Initiative Generation Study 1 Prescreening Cohort Study. Lancet Healthy Longevity In Press 2026.Pierson L, Gibert S, Orszag L, Sullivan H, Largent EA, Persad G: Bioethicists’ Views on Ethical Research: Results of the Views in Bioethics Survey. Ethics & Human Research In Press 2026.
Largent EA, Grill JD, Karlawish J, Bleakley A: Characterizing the Research Participant Recruitment Funnel for Alzheimer’s Secondary Prevention Trials: Results from A Survey of U.S. Adults. Alzheimer's & Dementia: Behavior & Socioeconomics of Aging 1(3), September 2025 Notes: doi: 10.1002/bsa3.70035. Epub 2025 Aug 28.
Nelson R, Kious B, Moore B, Largent EA, Blumenthal-Barby JS : Is Suffering A Useless Concept? American Journal of Bioethics 25(8), August 2025 Notes: doi: 10.1080/15265161.2024.2353799. Epub 2024 Jun 6.
O’Brien K, Largent EA, Karlawish J: Communicating a Diagnosis of Mild Cognitive Impairment or Dementia. JAMA July 2025 Notes: doi: 10.1001/jama.2025.13006. Epub ahead of print. Peer reviewed.
McCoy MS, Gaines M, Joffe S, Kanter GP, Largent EA, Lo B, Lynch HF, Whelan A, Mello M: A Framework for Assessing the Permissibility of Academic Leaders’ Outside Activities. The Millbank Quarterly June 2025 Notes: doi: 10.1111/1468-0009.70024. Epub ahead of print.
Lynch HF, Largent EA, McCoy MS, Joffe S: Advancing Trust in Science: Institutional Obligations to Promote Research Integrity. Journal of Law, Medicine, and Ethics June 2025 Notes: Introduction to special issue co-edited with Lynch HF, McCoy MS, and Joffe S.
oldstein CE, du Toit J, Murphy NB, Nicholls SG, Shaw JF, Althabe F, Binik A, Brehaut J, Eldridge S, Ferrand RA, Gillies K, Giraudeau B, van der Graaf R, Hemkens LG, Hemming K, Johri M, Kim SYH, Largent E, London AJ, Mbuagbaw L, Mitchell SL, Smith M, Tugwell P, Treweek S, Welch VA, Taljaard M, Weijer C.: Gaps in the Ottawa Statement on the Ethical Design and Conduct of Cluster Randomized Trials: A Citation Analysis Reveals A Need for Updated Ethics Guidelines. Research Integrity and Peer Review 10(1), June 2025 Notes: doi: 10.1186/s41073-025-00166-y.
Largent EA: Autistic People Shouldn't Be the Only Ones Worried by RFK Jr.'s Research Agenda. MedPage Today June 2025 Notes: https://www.medpagetoday.com/opinion/second-opinions/116138?trw=no.
Bleakley A, Maloney EK, Hennessy M, Hull S, Harkins K, Largent E, Ashford M, Kwang W, Byrd DR, Nosheny R, Karlawish J, Langbaum JB: Theory-Based Message Design for Recruitment of Underrepresented Racial/Ethnic Groups Into Alzheimer's-Focused Research Registries. Health Education & Behavior 52(3), June 2025 Notes: doi: 10.1177/10901981241296124. Epub 2024 Nov 19.