Emily A Largent JD, PhD, RN

faculty photo
Emanuel and Robert Hart Associate Professor in Bioethics
Senior Fellow, Leonard Davis Institute of Health Economics, University of Pennsylvania
Division Chief, Medical Ethics, Department of Medical Ethics & Health Policy
Department: Medical Ethics and Health Policy

Contact information
1403 Blockley Hall
423 Guardian Drive
Philadelphia, PA 19104
Education:
BS
Georgetown University, 2004.
BS (Nursing)
University of Pennsylvania, 2006.
PhD
Harvard University, 2016.
JD
Harvard Law School, 2016.
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Selected Publications

Neumann LTV, Mahinrad S, Abner E, Borson S, Byrd G, Carrillo MC, Clark L, Correro AN, Deters K, Dilworth-Anderson P, Edelmayer RM, Flatt J, Glover C, Grill J, Hill CV, Karikari T, Ketchum F, Largent EA, Lingler J, Luchsinger J, Maestre G, Mielke M, O’Bryant S, Okonkwo O, Parker M, Rahman-Filipiak AM, Raman R, Schindler S, Soria J, Stites S, Suchy-Dicey AM, Wharton W, Whitmer R, Wiese LAK, Windon C, Kind A, Barnes L: Mitigating Disparities in Diagnosis of Dementia. Alzheimer's & Dementia: Behavior & Socioeconomics of Aging In Press 2026.

Pierson L, Gibert S, Orszag L, Sullivan H, Largent EA, Persad G: Bioethicists’ Views on Ethical Research: Results of the Views in Bioethics Survey. Ethics & Human Research In Press 2026.

Erickson CM, Langlois CM, Wood EM, Mim R, Howe S, Ofidis D, Egleston BL, Harkins L, Largent EA, Roberts JS, Reiman EM, Denkinger M, Ashton NJ, Karlawish J, Bradbury AR, Langbaum JB: Evaluation of self-mediated alternatives for risk testing education and return of results (eSMARTER) study: A randomized study of methods for returning APOE and pTau-217 results. Alzheimer's & Dementia: Translational Research & Clinical Interventions 11, November 2025.

Langbaum JB, Bradbury AR, Egleston BL, McCarty Wood E, Langlois CM, Largent E, Harkins K, Erickson CM, Stites S, Oyen E, Riviere ME, Liu F, Graf A, Kim S, Grill JD, Reiman EM, Tariot PN, Roberts JS, Karlawish J. : Impact of Learning APOE Genotype on Cognitively Unimpaired Adults: A Pre-Screening Cohort Study of the Alzheimer’s Prevention Initiative Generation Study 1. Lancet Healthy Longevity November 2025.

Houtz C, Largent E: The Stories We Tell About Genetics: Freedom, Disability, and Determinism. American Journal of Bioethics 25: 82, November 2025.

Houtz C, Largent EA: Pursuing the Best Life in the Age of Preimplantation Whole Genome Sequencing: Ethical Considerations for Preimplantation Genetic Testing. Fertility and Sterility October 2025 Notes: Cassie Houtz completed this during her T32 post-doctoral fellowship in MEHP.

Morain SR, Gelinas L, Wendler D, O’Rourke PP, Largent EA: Reflections on a Principal of Research Ethics: Tom Beauchamp, Moral Specification, and Waivers of Informed Consent. American Journal of Bioethics October 2025.

Largent EA, Grill JD, Karlawish J, Bleakley A: Characterizing the Research Participant Recruitment Funnel for Alzheimer’s Secondary Prevention Trials: Results from A Survey of U.S. Adults. Alzheimer's & Dementia: Behavior & Socioeconomics of Aging 1(3), September 2025 Notes: doi: 10.1002/bsa3.70035. Epub 2025 Aug 28.

Nelson R, Kious B, Moore B, Largent EA, Blumenthal-Barby JS : Is Suffering A Useless Concept? American Journal of Bioethics 25(8), August 2025 Notes: doi: 10.1080/15265161.2024.2353799. Epub 2024 Jun 6.

O’Brien K, Largent EA, Karlawish J: Communicating a Diagnosis of Mild Cognitive Impairment or Dementia. JAMA July 2025 Notes: doi: 10.1001/jama.2025.13006. Epub ahead of print. Peer reviewed.

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Last updated: 12/01/2025
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