Selected Publications

Rurik JG, Aghajanian H, Epstein JA: Immune Cells and Immunotherapy for Cardiac Injury and Repair. Circ Res 128(11): 1766-1779, May 2021.

Aghajanian H, Kimura T, Hancock AS, Li L, Scholler J, Han W, Wang T, Bedi K, Morley MP, Wirth D, Margulies KB, Jain R, Puré E, Albelda SM, June CH, Epstein JA: Targeting cardiac fibrosis with engineered T cells. Nature 573(7774): 430-433, Sep 2019.

Artap S, Manderfield LJ, Smith CL, Poleshko A, Aghajanian H, See K, Li L, Jain R, Epstein JA: Endocardial Hippo signaling regulates myocardial growth and cardiogenesis. Dev Biol 440(1): 22-30, Aug 2018.

Pauerstein P, Tellez K, Willmarth KB, Park KM, Hsueh B, Arda HE, Gu X, Aghajanian H, Deisseroth K, Epstein JA, Kim SE: A radial axis defined by semaphorin-to-neuropilin signaling controls pancreatic islet morphogenesis. Development 144(20): 3744-3754, Oct 2017.

Poleshko A, Shah PP, Gupta M, Babu A, Morley MP, Manderfield LJ, Ifkovits JL, Calderon D, Aghajanian H, Sierra-Pagán JE, Sun Z, Wang Q, Li L, Dubois NC, Morrisey EE, Lazar MA, Smith CL, Epstein JA, Jain R: Genome-Nuclear Lamina Interactions Regulate Cardiac Stem Cell Lineage Restriction. Cell 171(3): 573-587, Oct 2017.

Aghajanian H, Cho YK, Rizer NW, Wang Q, Li L, Degenhardt K, Jain R: Pdgfrα functions in endothelial-derived cells to regulate neural crest cells and the development of the great arteries. Dis Model Mech 10(9): 1101-1108, Sep 2017.

Ramjee V, Li D, Manderfield LJ, Liu F, Engleka KA, Aghajanian H, Rodell CB, Lu W, Ho V, Wang T, Li L, Singh A, Cibi DM, Burdick JA, Singh MK, Jain R, Epstein JA: Epicardial YAP/TAZ orchestrate an immunosuppressive response following myocardial infarction. J Clin Invest 127(3): 899-911, Mar 2017.

Aghajanian H, Cho YK, Manderfield LJ, Herling MR, Gupta M, Ho VC, Li L, Degenhardt K, Aharonov A, Tzahor E, Epstein JA: Coronary vasculature patterning requires a novel endothelial ErbB2 holoreceptor. Nat Commun 7: 12038, Jun 2016.

Jain R, Barkauskas CE, Takeda N, Bowie EJ, Aghajanian H, Wang Q, Padmanabhan A, Manderfield LJ, Gupta M, Li D, Li L, Trivedi CM, Hogan BLM, Epstein JA: Plasticity of Hopx(+) type I alveolar cells to regenerate type II cells in the lung. Nat Commun 6: 6727, Apr 2015.

Epstein JA, Aghajanian H, Singh MK: Semaphorin signaling in cardiovascular development. Cell Metab 21(2): 163-173, Feb 2015.