Gerald B. W. Wertheim, MD, PhD
Associate Professor of Clinical Pathology and Laboratory Medicine
Hematopathologist, Hospital of the University of Pennsylvania
Assistant Director, Division of Genomic Diagnostics
Children's Hospital of Philadelphia
Director of Hematopathology, The Children's Hospital of Philadelphia
Department: Pathology and Laboratory Medicine
Contact information
Department of Pathology and Laboratory Medicine
Children's Hospital of Philadelphia
5199B Main Building
5th Floor
3401 Civic Center Boulevard
Philadelphia, PA 19104
Children's Hospital of Philadelphia
5199B Main Building
5th Floor
3401 Civic Center Boulevard
Philadelphia, PA 19104
Office: 267-970-5918
Fax: 215-590-1736
Fax: 215-590-1736
Email:
wertheimg@email.chop.edu
wertheimg@email.chop.edu
Education:
BS (Chemistry)
Yale University, New Haven CT, 1994.
PhD (Cancer Biology)
University of Pennsylvania School of Medicine, 2004.
MD (Medicine)
University of Pennsylvania School of Medicine, 2005.
Permanent linkBS (Chemistry)
Yale University, New Haven CT, 1994.
PhD (Cancer Biology)
University of Pennsylvania School of Medicine, 2004.
MD (Medicine)
University of Pennsylvania School of Medicine, 2005.
Selected Publications
Luo M, Wong D, Zelley K, Wu J, Schubert J, Denenberg EH, Fanning EA, Chen J, Gallo D, Golenberg N, Patel M, Conlin LK, Maxwell KN, Wertheim GB, Surrey LF, Zhong Y, Brodeur GM, MacFarland SP, Li MM: Identification of TP53 Germline Variants in Pediatric Patients Undergoing Tumor Testing: Strategy and Prevalence. J Natl Cancer Inst May 2024 Notes: Online Ahead of Print.Myers RM, Devine K, Li Y, Lawrence S, Barz Leahy A, Liu H, Vernau L, Callahan C, Baniewicz D, Kadauke S, McGuire R, Wertheim GB, Kulikovskaya I, Gonzalez VE, Fraietta JA, DiNofia Am, Hunger SP, Rheingold SR, Aplenc R, June CH, Grupp SA, Wray L, Maude SL: Reinfusion of CD19 CAR T Cells for Relapse Prevention and Treatment in Children With Acute Lymphoblastic Leukemia. Blood Adv 14(8): 2182-2192, May 2024.
Liu Y, Li Q, Song L, Gong C, Tang S, Budinich KA, Vanderbeck A, Mathias KM, Wertheim GB, Nguyen SC, Outen R, Joyce EF, Maillard I, Wan L: Condensate-promoting ENL Mutation Drives Tumorigenesis in Vivo Through Dynamic Regulation of Histone Modifications and Gene Expression. Cancer Discov April 2024 Notes: Online Ahead of Print.
Placek A, Lockhart B, Miller KP, Wertheim GB, Maude SL, Wood BL, Kovach AE: Maturational Dyssynchrony in Benign B-cell Precursors Following Lymphocyte Depleting Chemotherapy: A potential Pitfall for B-lymphoblastic Leukemia Minimal/Measurable Residual Disease (MRD) Flow Cytometry Analysis. Cytometry B Clin Cytom 106(2): 138-141, March 2024.
Sung PJ, Selvam M, Riedel SS, Xie HM, Bryant K, Manning B, Wertheim GB, Kulej K, Pham L, Bowman RL, Peresie J, Nemeth MJ, Levine RL, Garcia BA, Meyer SE, Sidoli S, Bernt KM, Carroll M: FLT3 Tyrosine Kinase Inhibition Modulates PRC2 and Promotes Differentiation in Acute Myeloid Leukemia. Leukemia 38(2): 291-301, February 2024.
Newman H, Egan Clark M, Wong D, Wu J, Brodeur GM, Hunger SP, Tasian SK, Olson T, Warren JT, Teachey DT, Bona K, Schubert J, Golenberg N, Patel M, Denenberg EH, Fanning EA, Chen J, Luke T, Charles S, Gallo D, Cao K, Fu W, Fan Z, Surrey LF, Wertheim G, Luo M, MacFarland SP, Li MM, Zhong Y: Genomic profiling of pediatric hematologic malignancies and diagnosis of cancer predisposition syndromes: tumor-only versus paired tumor-normal sequencing. Haematologica February 2024 Notes: Online Ahead of Print.
Brandstadter JD, De Martin A, Lϋtge M, Ferreira A, Gaudette BT, Stanossek Y, Shumei Wang 3, Gonzalez MV, Camiolo E, Wertheim G, Austin B, Allman D, Bagg A, Lim MS, Fajgenbaum DC, Aster JC, Ludewig B, Maillard I: A Novel Cryopreservation and Biobanking Strategy to Study Lymphoid Tissue Stromal Cells in Human Disease. Eur J Immunol 53(9): e2250362, September 2023.
Izumi K, Ganetzky RD, Wertheim G, Skraban CM, Bedoukian EC, Wilkens A, Fincher C, Thomas NH, Ginsberg JP, Rheingold SR, Conlin LK, Deardorff MA: Co-Occurrence of Pallister-Killian Syndrome and Burkitt Lymphoma in a Patient with Near-Normal Neurocognitive Development. Mol Syndromol 14(4): 303-309, August 2023.
Qin VL, Verkuil L, Zangeaneh T, Wertheim G, Davidson SL: Iris and Orbital Myeloid Sarcoma in a Pediatric Patient. J AAPOS 27(3), June 2023.
Maura F, Ziccheddu B, Xiang JZ, Bhinder B, Rosiene J, Abascal F, Maclachlan KH, Eng KW, Uppal M, He F, Zhang W, Gao Q, Yellapantula VD, Trujillo-Alonso V, Park SI, Oberley MJ, Ruckdeschel E, Lim MS, Wertheim GB, Barth MJ, Horton TM, Derkach A, Kovach AE, Forlenza CJ, Zhang Y, Landgren O, Moskowitz CH, Ethel Cesarman E, Imielinski M, Elemento O, Roshal M, Giulino-Roth L: Molecular Evolution of Classic Hodgkin Lymphoma Revealed Through Whole Genome Sequencing of Hodgkin and Reed Sternberg Cells. Blood Cancer Discovery 4(3): 208-227, May 2023.