Gerald B. W. Wertheim, MD, PhD
Associate Professor of Clinical Pathology and Laboratory Medicine
Hematopathologist, Hospital of the University of Pennsylvania
Assistant Director, Division of Genomic Diagnostics
Children's Hospital of Philadelphia
Director of Hematopathology, The Children's Hospital of Philadelphia
Department: Pathology and Laboratory Medicine
Contact information
Department of Pathology and Laboratory Medicine
Children's Hospital of Philadelphia
5199B Main Building
5th Floor
3401 Civic Center Boulevard
Philadelphia, PA 19104
Children's Hospital of Philadelphia
5199B Main Building
5th Floor
3401 Civic Center Boulevard
Philadelphia, PA 19104
Office: 267-970-5918
Fax: 215-590-1736
Fax: 215-590-1736
Email:
wertheimg@email.chop.edu
wertheimg@email.chop.edu
Education:
BS (Chemistry)
Yale University, New Haven CT, 1994.
PhD (Cancer Biology)
University of Pennsylvania School of Medicine, 2004.
MD (Medicine)
University of Pennsylvania School of Medicine, 2005.
Permanent linkBS (Chemistry)
Yale University, New Haven CT, 1994.
PhD (Cancer Biology)
University of Pennsylvania School of Medicine, 2004.
MD (Medicine)
University of Pennsylvania School of Medicine, 2005.
Selected Publications
Maura F, Ziccheddu B, Xiang JZ, Bhinder B, Rosiene J, Abascal F, Maclachlan KH, Eng KW, Uppal M, He F, Zhang W, Gao Q, Yellapantula VD, Trujillo-Alonso V, Park SI, Oberley MJ, Ruckdeschel E, Lim MS, Wertheim GB, Barth MJ, Horton TM, Derkach A, Kovach AE, Forlenza CJ, Zhang Y, Landgren O, Moskowitz CH, Ethel Cesarman E, Imielinski M, Elemento O, Roshal M, Giulino-Roth L: Molecular Evolution of Classic Hodgkin Lymphoma Revealed Through Whole Genome Sequencing of Hodgkin and Reed Sternberg Cells. Blood Cancer Discovery February 2023 Notes: Online Ahead of Print.Xu F, Viaene AN, Ruiz J, Schubert J, Wu J, Chen J, Cao K, Fu W, Bagatell R, Fan Z, Long A, Pagliaroli L, Zhong Y, Luo M, Kreiger PA, Surrey LF, Wertheim GB, Cole KA, Li MM, Santi M, Storm PB: Novel ATXN1/ATXN1L::NUTM2A Fusions Identified in Aggressive Infant Sarcomas With Gene Expression and Methylation Patterns Similar to CIC-rearranged Sarcoma. Acta Neuropathologica Communications 10(1): 102, July 2022.
Guney E, Lucas CHG, Qi Z, Yu J, Zhang R, Ohgami RS, Rubenstein JL, Boué DR, Schafernak KT, Wertheim GB, Dahiya S, Giulino-Roth L, Attarbaschi A, Barth MJ, Kothari S, Abla O, Cohen AL, Mendez JS, Bollen AW, Perry A, Tihan T, Pekmezci M, Solomon DA, Wen KW: A Genetically Distinct Pediatric Subtype of Primary CNS Large B-cell Lymphoma is Associated with Favorable Clinical Outcome. Blood Advances 6(10): 3189-3193, May 2022.
Wing , Xu J, Meng W, Rosenfeld AM, Li EY, Wertheim G, Paessler M, Bagg A, Frank D, Tan K, Teachey DT, Lim MS, Luning Prak E, Fajgenbaum DC, Pillai V: Transcriptome and Unique Cytokine Microenvironment of Castleman Disease. Modern Pathology 35(4): 451-461, April 2022.
Xu F, Aref-Eshghi E, Wu J, Schubert J, Wertheim G, Bhatti T, Pogoriler J, Patel Maha, Cao K, Long A, Fan Z, Denenberg EH, Fanning EA, Wiilmoth DM, Luo M, Conlin LK, Dain AS, Zelley K, Baldino S, Balamuth N, MacFarland S, Li MM, Zhong Y: A Novel TP53 Tandem Duplication in a Child With Li-Fraumeni Syndrome. Cold Spring Harbor Molecular Case Studies 8(3): a006181, April 2022.
Myers RM, Li Y, Leahy AB, Barrett DM, Teachey DT, Callahan C, Fasano CC, Rheingold SR, DiNofia A, Wray L, Aplenc R, Baniewicz D, Liu H, Shaw PA, Pequignot E, Getz KD, Brogdon JL, Fesnak AD, Siegel DL, Davis MM, Bartoszek C, Lacey SF, Hexner EO, Chew A, Wertheim GB, Levine BL, June CH, Grupp SA, Maude SL: Humanized CD19-Targeted Chimeric Antigen Receptor (CAR) T Cells in CAR-Naive and CAR-Exposed Children and Young Adults With Relapsed or Refractory Acute Lymphoblastic Leukemia. Journal of Clinical Oncology 39(27): 3044-3055, September 2021.
Wertheim G: Infant Acute Leukemia. Clinics in Laboratory Medicine 41(3): 541-550, September 2021.
Nelson ND, Meng W, Rosenfeld AM, Bullman S, Pedamallu CS, Nomburg JL, Wertheim GB, Paessler ME, Pinkus G, Hornick JL, Meyerson M, Luning Prak ET, Pillai V: Characterization of Plasmacytoid Dendritic Cells, Microbial Sequences, and Identification of a Candidate Public T-Cell Clone in Kikuchi-Fujimoto Disease. Pediatric and Developmental Pathology 24(3): 193-205, June 2021.
Zhong Y, Wu, J, Lin F, Luo M, Surrey L, Schubert J, Patel M, Xu F, Pechter K, Cao K, Gallo D, Denenberg E, Fanning E, Chen J, Fan Z, MacFarland S, Paessler M, Margolskee M, Pillau V, Aplenc R, Bernt K, Rheingold S, Tasian S, Hunger S, Wertheim G, Li M: Genomic Characterization of 747 Pediatric Hematological Malignancies. 2021 ACMG Annual Clinical Genetics Meeting April 2021 Notes: Poster Presentation.
Kadauke S, Myers RM, Li Y, Aplenc R, Baniewicz D, Barrett DM, Barz Leahy A, Callahan C, Dolan JG, Fitzgerald JC, Gladney W, Lacey SF, Liu H, Maude SL, McGuire R, Motley LS, Teachey DT, Wertheim GB, Wray L, DiNofia AM, Grupp SA: Risk-Adapted Preemptive Tocilizumab to Prevent Severe Cytokine Release Syndrome After CTL019 for Pediatric B-Cell Acute Lymphoblastic Leukemia: A Prospective Clinical Trial. Journal of Clinical Oncology 39(8): 920-930, March 2021.