Gerald B. W. Wertheim, MD, PhD

faculty photo
Associate Professor of Clinical Pathology and Laboratory Medicine
Department: Pathology and Laboratory Medicine

Contact information
Department of Pathology and Laboratory Medicine
Children's Hospital of Philadelphia
5199B Main Building
5th Floor
3401 Civic Center Boulevard
Philadelphia, PA 19104
Office: 267-970-5918
Fax: 215-590-1736
Education:
BS (Chemistry)
Yale University, New Haven CT, 1994.
PhD (Cancer Biology)
University of Pennsylvania School of Medicine, 2004.
MD (Medicine)
University of Pennsylvania School of Medicine, 2005.
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Selected Publications

Jung HS, Lin F, Wolpaw A, Reilly AF, Margolskee E, Luo M, Wertheim GB, Li MM: A Novel KMT2A-ARHGEF12 Fusion Gene Identified in a High-Grade B-cell Lymphoma. Cancer Genetics Page: 41-43, August 2020 Notes: Online ahead of print.

Hurtz C, Wertheim GB, Loftus JP, Blumenthal D, Lehman A, Li Y, Bagashev A, Manning B, Cummins KD, Burkhardt JK, Perl AE, Carroll M, Tasian SK: Oncogene-independent BCR-like signaling adaptation confers drug resistance in Ph-like ALL. The Journal of Clinical Investigation 130(7): 3637-3653, July 2020.

Rentas S, Pillai V, Wertheim GB, Akgumus GT, Nichols KE, Deardorff MA, Conlin LK, Li MM, Olson TS, Luo M : Evolution of Histomorphologic, Cytogenetic, and Genetic Abnormalities in an Untreated Patient With MIRAGE Syndrome. Cancer Genetics 245: 42-48, July 2020.

Cai Z, Aguilera F, Ramdas B, Daulatabad SV, Srivastava R, Kotzin JJ, Carroll M, Wertheim G, Williams A, Janga SC, Zhang C, Henao-Mejia J, Kapur R.: Targeting Bim via a lncRNA Morrbid Regulates the Survival of Preleukemic and Leukemic Cells. Cell Reports 31(12): 107816, June 2020.

Nelson ND, Meng W, Rosenfeld A, Bullman S, Pedamullu CS, Nomburg JL, Wertheim GBW, Paessler, ME, Pinkus GS, Hornick JL, Meyerson ML, Prak EL, Pillai V: Characterization of Plasmacytoid Dendritic Cells, Microbial Sequences, and Identification of a Candidate Public T-cell Clone in Kikuchi-Fujimoto Lymphadenitis. United States and Canadian Academy of Pathology 2020 Los Angeles, California March 2020.

Arenas DJ, Floess K, Kobrin D, Pai RL, Srkalovic MB, Tamakloe MA, Rasheed R, Ziglar J, Khor J, Parente SAT, Pierson SK, Martinez D, Wertheim GB, Kambayashi T, Baur J, Teachey DT, Fajgenbaum DC: Increased mTOR activation in idiopathic multicentric Castleman disease. Blood 135(19): 1673‐1684, March 2020 Notes: Epub ahead of print.

Bellissimo DC, Chen CH, Zhu Q, Bagga S, Lee CT, He B, Wertheim GB, Jordan M, Tan K, Worthen GS, Gilliland DG, Speck NA: Runx1 negatively regulates inflammatory cytokine production by neutrophils in response to Toll-like receptor signaling. Blood Advances 4(6): 1145-1158, March 2020.

Yang G, Faude S, Paessler ME, Wertheim GBW, Pillai V: CD19-Negative B-ALL Relapses after CAR T Cell Therapy are Associated with a Hypermutator Phenotype United States and Canadian Academy of Pathology 2020 Los Angeles, California March 2020.

Faude S, Pillai V, Paessler ME, Wertheim GBW: Absolute Lymphocyte Count Kinetics Correlates with Response and Toxicity in CAR T Therapy. United States and Canadian Academy of Pathology 2020 Los Angeles, California March 2020.

Oberley MJ, Raikar SS, Wertheim GB, Malvar J, Sposto R,Rabin KR, Punia JN, Seif AE, Cahen VC, Schore RJ, Luca DC, Guinipero T, Woods WG, O'Gorman MRG, Orgel E: Significance of minimal residual disease in pediatric mixed phenotype acute leukemia: a multicenter cohort study. Leukemia February 2020 Notes: Epub ahead of print.

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Last updated: 09/18/2020
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