1e
19
1
49
2
2
18
1b
1d
18
49
65
1d
2 29
1d
25
Michael Alan Levine, M.D., FAAP, FACP, MACE
78
65
Emeritus Professor CE of Pediatrics (Endocrinology and Diabetes)
7
61
Department: Pediatrics
4
1
b
1d
46
Contact information
55
4
3
3
1d
55
The Children's Hospital of Philadelphia
23 3615 Civic Center Boulevard
48 Abramson Research Building, Room 510A
Philadelphia, PA 19104
26
23 3615 Civic Center Boulevard
48 Abramson Research Building, Room 510A
Philadelphia, PA 19104
2e
Office: 215-590-3174
32 Fax: 215-590-3053
34 Lab: (267) 426-2382
18
81
32 Fax: 215-590-3053
34 Lab: (267) 426-2382
18
Email:
levinem@chop.edu
12
levinem@chop.edu
18
Publications
23 a
3
2
29
4
b
1f
23 a
13
Education:
21 9 A.B. c
3b Rutgers College, New Brunswick, NJ, 1972.
21 9 M.D. c
64 Drexel University (formerly Hahnemann) College of Medicine, Philadelpia, PA, 1976.
21 7 ML 1a (Master of Law) c
43 University of Pennsylania Carey Law School, 2024.
c
3
3
3
3
8d
Permanent link21 9 A.B. c
3b Rutgers College, New Brunswick, NJ, 1972.
21 9 M.D. c
64 Drexel University (formerly Hahnemann) College of Medicine, Philadelpia, PA, 1976.
21 7 ML 1a (Master of Law) c
43 University of Pennsylania Carey Law School, 2024.
c
2 29
21
1e
1d
24
2b
29
27
23
18e Li, Dong, Mailand, Niels, Ewing, Emma, Hoffmann, Saskia, Caswell, Richard C, Pang, Lewis, Eason, Jacqueline, Dou, Ying, Sullivan, Kathleen E, Hakonarson, Hakon: Quantitative hypermorphic FAM111A alleles cause autosomal recessive Kenny-Caffey syndrome type 2 and osteocraniostenosis. JCI insight 10(6): e186862, 2025.
118 Alzoebie, Lama, Li, Dong, Wang, Xiang, Weber, David R, Levine, Michael A: Unusual PHEX variants implicate uncommon genetic mechanisms for X-linked hypophosphatemic rickets. JBMR plus 9(1): ziae152, 2025.
183 Stoffers, Ashley J, Mancilla, Edna E, Levine, Michael A, Mayer, Michael, Monk, Heather M, Rosano, Joseph, Weber, David R: Clinical Efficacy of Zoledronic Acid on Fracture Reduction in Youth With Primary and Secondary Skeletal Fragility. The Journal of Clinical Endocrinology & Metabolism Page: dgae661, 2024.
12d Wachtel, H, Ermer, JP, Fraker, DL, Kelz, RR, Kelly, TLA, Hackl, M, Levine, MA: Circulating microRNA as a Potential Biomarker for Skeletal Disease in Primary Hyperparathyroidism A Case-control Study. Annals of Surgery 2024.
112 Wu, Calvin C, Econs, Michael J, DiMeglio, Linda A, Insogna, Karl L, Levine, Michael A, Orchard, Paul J, Miller, Weston P, Petryk, Anna, Rush, Eric T, Shoback, Dolores M: Advance Article. 2024.
11e Benson, Matthew, Wyatt, Rachael A, Levine, Michael, Gorvin, Caroline M: An activating CaSR Variant with biased signaling reveals a critical residue for Gα11 coupling. Journal of Bone and Mineral Research 2024.
17b Li, Dong, de Beur, Suzanne Jan, Hou, Cuiping, Ruzhnikov, Maura RZ, Seeley, Hilary, Cutting, Garry R, Sheridan, Molly B, Levine, Michael A: Recurrent small variants in NESP55/NESPAS associated with broad GNAS methylation defects and pseudohypoparathyroidism type 1B. JCI insight 9(24): e185874, 2024.
13a Ralph, Douglas, Levine, Michael, Millán, José Luis, Uitto, Jouni, Li, Qiaoli: Weighing the evidence for the roles of plasma versus local pyrophosphate in ectopic calcification disorders. Journal of Bone and Mineral Research April 2023.
1b7 Watts, Nelson B, Bilezikian, John P, Bone, Henry G, Clarke, Bart L, Denham, Douglas, Levine, Michael A, Mannstadt, Michael, Peacock, Munro, Rothman, Jeffrey G, Vokes, Tamara J: Long-Term Safety and Efficacy of Recombinant Human Parathyroid Hormone (1-84) in Adults with Chronic Hypoparathyroidism. Journal of the Endocrine Society Page: bvad043, April 2023.
2c
7
1d
1f
Selected Publications
1dd Xu, Xiaoqin, Shen, Yingxiao, Yang, Wei, Wei, Haiyan, Chen, Ting, Chen, Linqi, Wang, Zhihua, Yao, Hui, Zhang, Jianping, Chen, Ruimin, Sun, Yan, Dong, Guanping, Huang, Ke, Levine, M A, Fu, Junfen, Wu, Wei: Clinical Evaluation and Molecular Analysis of Genetic and Epigenetic Inactivation Defects in GNAS in children: A multicenter experience in China. European journal of endocrinology 2025.18e Li, Dong, Mailand, Niels, Ewing, Emma, Hoffmann, Saskia, Caswell, Richard C, Pang, Lewis, Eason, Jacqueline, Dou, Ying, Sullivan, Kathleen E, Hakonarson, Hakon: Quantitative hypermorphic FAM111A alleles cause autosomal recessive Kenny-Caffey syndrome type 2 and osteocraniostenosis. JCI insight 10(6): e186862, 2025.
118 Alzoebie, Lama, Li, Dong, Wang, Xiang, Weber, David R, Levine, Michael A: Unusual PHEX variants implicate uncommon genetic mechanisms for X-linked hypophosphatemic rickets. JBMR plus 9(1): ziae152, 2025.
183 Stoffers, Ashley J, Mancilla, Edna E, Levine, Michael A, Mayer, Michael, Monk, Heather M, Rosano, Joseph, Weber, David R: Clinical Efficacy of Zoledronic Acid on Fracture Reduction in Youth With Primary and Secondary Skeletal Fragility. The Journal of Clinical Endocrinology & Metabolism Page: dgae661, 2024.
12d Wachtel, H, Ermer, JP, Fraker, DL, Kelz, RR, Kelly, TLA, Hackl, M, Levine, MA: Circulating microRNA as a Potential Biomarker for Skeletal Disease in Primary Hyperparathyroidism A Case-control Study. Annals of Surgery 2024.
112 Wu, Calvin C, Econs, Michael J, DiMeglio, Linda A, Insogna, Karl L, Levine, Michael A, Orchard, Paul J, Miller, Weston P, Petryk, Anna, Rush, Eric T, Shoback, Dolores M: Advance Article. 2024.
11e Benson, Matthew, Wyatt, Rachael A, Levine, Michael, Gorvin, Caroline M: An activating CaSR Variant with biased signaling reveals a critical residue for Gα11 coupling. Journal of Bone and Mineral Research 2024.
17b Li, Dong, de Beur, Suzanne Jan, Hou, Cuiping, Ruzhnikov, Maura RZ, Seeley, Hilary, Cutting, Garry R, Sheridan, Molly B, Levine, Michael A: Recurrent small variants in NESP55/NESPAS associated with broad GNAS methylation defects and pseudohypoparathyroidism type 1B. JCI insight 9(24): e185874, 2024.
13a Ralph, Douglas, Levine, Michael, Millán, José Luis, Uitto, Jouni, Li, Qiaoli: Weighing the evidence for the roles of plasma versus local pyrophosphate in ectopic calcification disorders. Journal of Bone and Mineral Research April 2023.
1b7 Watts, Nelson B, Bilezikian, John P, Bone, Henry G, Clarke, Bart L, Denham, Douglas, Levine, Michael A, Mannstadt, Michael, Peacock, Munro, Rothman, Jeffrey G, Vokes, Tamara J: Long-Term Safety and Efficacy of Recombinant Human Parathyroid Hormone (1-84) in Adults with Chronic Hypoparathyroidism. Journal of the Endocrine Society Page: bvad043, April 2023.
2c