Michael Alan Levine, M.D., FAAP, FACP, MACE
Emeritus Professor CE of Pediatrics (Endocrinology and Diabetes)
Department: Pediatrics
Contact information
The Children's Hospital of Philadelphia
3615 Civic Center Boulevard
Abramson Research Building, Room 510A
Philadelphia, PA 19104
3615 Civic Center Boulevard
Abramson Research Building, Room 510A
Philadelphia, PA 19104
Office: 215-590-3174
Fax: 215-590-3053
Lab: (267) 426-2382
Fax: 215-590-3053
Lab: (267) 426-2382
Email:
levinem@chop.edu
levinem@chop.edu
Publications
Education:
A.B.
Rutgers College, New Brunswick, NJ, 1972.
M.D.
Drexel University (formerly Hahnemann) College of Medicine, Philadelpia, PA, 1976.
ML (Master of Law)
University of Pennsylania Carey Law School, 2024.
Permanent linkA.B.
Rutgers College, New Brunswick, NJ, 1972.
M.D.
Drexel University (formerly Hahnemann) College of Medicine, Philadelpia, PA, 1976.
ML (Master of Law)
University of Pennsylania Carey Law School, 2024.
Selected Publications
Karen Huang, Rachel M Hurley, Susan T Sotardi, Portia A. Kreiger, Lauren Leonard, Ang Simpson, Sheila J Carroll, Michael Levine, Theodore W Laetsch: Sustained Response to Trametinib in Central Giant Cell Granuloma with KRAS-Gain of Function Mutation: A Case Report. JCO Precision Oncology 2026 Notes: In press.Usui, Toshiaki, Ishibashi, Shun, Tanaka, Ryojiro, Morito, Naoki, Hamada, Michito, Gogoleva, Natalia, Ning, Baoshuo, Kumaga, Eugenia, Oki, Mayuko, Tsunakawa, Yuki: Inhibition of MAFB and PI3K/AKT Signaling for Hereditary FSGS with Multicentric Carpotarsal Osteolysis. Journal of the American Society of Nephrology Page: 10.1681, 2026.
Xu, Xiaoqin, Shen, Yingxiao, Yang, Wei, Wei, Haiyan, Chen, Ting, Chen, Linqi, Wang, Zhihua, Yao, Hui, Zhang, Jianping, Chen, Ruimin, Sun, Yan, Dong, Guanping, Huang, Ke, Levine, M A, Fu, Junfen, Wu, Wei: Clinical Evaluation and Molecular Analysis of Genetic and Epigenetic Inactivation Defects in GNAS in children: A multicenter experience in China. European journal of endocrinology 2025.
Ing, Steven Wai, Bowden, Sasigarn A, Dahir, Kathryn, Florenzano, Pablo, Holm, Ingrid Adele, Khan, Sarah, Levine, Michael A, Moreira, Carolina Aguiar, Tabatabai, Laila, Ward, Leanne M: Effectiveness of Burosumab Versus Oral Phosphate and Active Vitamin D in Adults With X-Linked Hypophosphatemia (XLH) in a Real-World Setting: A 3-Year Follow-up of the XLH Disease Monitoring Program. Journal of Bone and Mineral Research. ASBMR, 2025.
Siggelkow, Heide, Vokes, Tamara, Gittoes, Neil, Ayodele, Olulade, Brandi, Maria Luisa, Castriota, Felicia, Levine, Michael A, Schaeffer Koziol, Carolyn, Rejnmark, Lars, Khan, Aliya A: Health-related quality of life in a cohort of 1070 patients with hypoparathyroidism. EUROPEAN JOURNAL OF ENDOCRINOLOGY 193(4): 428-439, 2025.
Ali, Dalal S, Chung, Zinnia, Kamel, Loay, Björnsdottir, Sigridur, Clarke, Bart L, Gittoes, Neil John, Hahner, Stephanie, Hofbauer, Lorenz C, Houillier, Pascal, Ing, Steven Wai: SUN-765 Retrospective Analysis of Pregnancy and Neonatal Outcomes in Hypoparathyroidism from the PARADIGHM Registry. Journal of the Endocrine Society 9(Supplement_1): bvaf149. 713, 2025.
Whittaker, Madelynn N, Testa, Lauren C, Quigley, Aidan, Brooks, Dominique L, Grandinette, Sarah A, Said, Hooda, Dwivedi, Garima, Jindal, Ishaan, Volpp, Daphne, Hacker, Julia L: Improved specificity and efficiency of in vivo adenine base editing therapies with hybrid guide RNAs. Nature Biomedical Engineering Page: 1-13, 2025.
Testa, Lauren C, Obiri-Yeboah, Dora, Said, Hooda, Qu, Ping, Levine, Michael A, Alameh, Mohamad-Gabriel, Musunuru, Kiran, Li, Qiaoli, Wang, Xiao: Liver-directed base editing of ABCC6 prevents ectopic calcification in a variant-humanized mouse model of pseudoxanthoma elasticum. Molecular Therapy Nucleic Acids 36(4), 2025.
Li, Dong, Mailand, Niels, Ewing, Emma, Hoffmann, Saskia, Caswell, Richard C, Pang, Lewis, Eason, Jacqueline, Dou, Ying, Sullivan, Kathleen E, Hakonarson, Hakon: Quantitative hypermorphic FAM111A alleles cause autosomal recessive Kenny-Caffey syndrome type 2 and osteocraniostenosis. JCI insight 10(6): e186862, 2025.
Alzoebie, Lama, Li, Dong, Wang, Xiang, Weber, David R, Levine, Michael A: Unusual PHEX variants implicate uncommon genetic mechanisms for X-linked hypophosphatemic rickets. JBMR plus 9(1): ziae152, 2025.