Yang Li, MD, PhD

faculty photo
Assistant Professor of Pathology and Laboratory Medicine at the Children's Hospital of Philadelphia
Department: Pathology and Laboratory Medicine

Contact information
Abramson Research Bldg. 712
The Children's Hospital of Philadelphia
3615 Civic Center Blvd.
Philadelphia, Pa 19104
Education:
B.A. (Biophysics)
Johns Hopkins University, 2007.
M.A. (Biophysics)
Johns Hopkins University, 2008.
Ph.D. (Cell and Molecular Biology)
University of Pennsylvania, 2013.
M.D.
University of Pennsylvania, 2015.
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Selected Publications

Hayeck, T. J., Li, Y., Mosbruger, T. L., Bradfield, J. P., Gleason, A. G., Damianos, G. L., Shaw, G. T., Duke, J. L., Conlin, L. K., Turner, T. N., Fernández-Viña, M. A., Sarmady, & M., Monos, D. S.: The impact of patterns in linkage disequilibrium and sequencing quality on the imprint of balancing selection. Genome Biology and Evolution, 16(2), 2024 Notes: https://doi.org/10.1093/gbe/evae009.

Li, Y., Mosbruger, T. L., Hayeck, T. J., Wells, A. D., Grant, S. F. A., & Monos, D.: Hi-C analysis using self-reference provides a more informative MHC chromatin interaction map. ASHI 48th Annual Meeting: P98. 2022.

Guderyon, M. J., Chen, C., Bhattacharjee, A., Ge, G., Fernandez, R. A., Gelfond, J. A. L., Gorena, K. M., Cheng, C. J., Li, Y., Nelson, J. F., Strong, R. J., Hornsby, P. J., Clark, R. A., & Li, S.: Mobilization‐based transplantation of young‐donor hematopoietic stem cells extends lifespan in mice. Aging Cell 19(3), 2020 Notes: https://doi.org/10.1111/acel.13110.

Chen, C., Guderyon, M. J., Li, Y., Ge, G., Bhattacharjee, A., Ballard, C., He, Z., Masliah, E., Clark, R. A., O’Connor, J. C., & Li, S.: Non-toxic HSC Transplantation-Based Macrophage/Microglia-Mediated GDNF Delivery for Parkinson’s Disease. Molecular Therapy - Methods & Clinical Development 17: 83-98, 2020 Notes: https://doi.org/10.1016/j.omtm.2019.11.013.

Henry, C., Zheng, N. Y., Huang, M., Cabanov, A., Rojas, K. T., Kaur, K., Andrews, S. F., Palm, A. E., Chen, Y. Q., Li, Y., Hoskova, K., Utset, H. A., Vieira, M. C., Wrammert, J., Ahmed, R., Holden-Wiltse, J., Topham, D. J., Treanor, J. J., Ertl, H. C., Schmader K.E, Cobey S., Krammer F., Hensley S. E, Greenberg H., He X.S., Wilson, P. C.: Influenza Virus Vaccination Elicits Poorly Adapted B Cell Responses in Elderly Individuals. Cell Host & Microbe 25(3): 357-366, 2019 Notes: https://doi.org/10.1016/j.chom.2019.01.002.

Balcerek, J., Jiang, J., Li, Y., Jiang, Q., Holdreith, N., Singh, B., Chandra, V., Lv, K., Ren, J., Rozenova, K., Li, W., Greenberg, R. A., & Tong, W.: Lnk/Sh2b3 deficiency restores hematopoietic stem cell function and genome integrity in Fancd2 deficient Fanconi anemia. Nature Communications 9(1): 3915, 2018 Notes: https://doi.org/10.1038/s41467-018-06380-1.

Li, Y., Alby, K., Watt, C. D., & Roth, J. J.: Integration of rapid molecular testing for influenza and RSV into existing diagnostic workflow. Association for Molecular Pathology 2016 Annual Meeting. 2016.

Shaffer, S. M., Joshi, R. P., Chambers, B. S., Sterken, D., Biaesch, A. G., Gabrieli, D. J., Li, Y., Feemster, K. A., Hensley, S. E., Issadore, D., & Raj, A.: Multiplexed detection of viral infections using rapid in situ RNA analysis on a chip. Lab on a Chip 15(15): 3170–3182, 2015 Notes: https://doi.org/10.1039/C5LC00459D.

Linderman, S. L., Chambers, B. S., Zost, S. J., Parkhouse, K., Li, Y., Herrmann, C., Ellebedy, A. H., Carter, D. M., Andrews, S. F., Zheng, N.-Y., Huang, M., Huang, Y., Strauss, D., Shaz, B. H., Hodinka, R. L., Reyes-Terán, G., Ross, T. M., Wilson, P. C., Ahmed, R., Bloom J. D., Hensley, S. E.: Potential antigenic explanation for atypical H1N1 infections among middle-aged adults during the 2013–2014 influenza season. Proceedings of the National Academy of Sciences 111(44): 15798–15803, 2014 Notes: https://doi.org/10.1073/pnas.1409171111.

Chambers, B. S., Li, Y., Hodinka, R. L., & Hensley, S. E.: Recent H3N2 Influenza Virus Clinical Isolates Rapidly Acquire Hemagglutinin or Neuraminidase Mutations When Propagated for Antigenic Analyses. Journal of Virology 88(18): 10986–10989, 2014 Notes: https://doi.org/10.1128/JVI.01077-14.

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Last updated: 10/14/2024
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