Andrew McKinstry-Wu, MD
Assistant Professor of Anesthesiology and Critical Care at the Hospital of the University of Pennsylvania
Attending Anesthesiologist, Hospital of the University of Pennsylvania
Faculty Member, Center for Sleep and Circadian Biology
Faculty Member, Neuroscience of Unconsciousness and Reanimation Research Alliance
Department: Anesthesiology and Critical Care
Contact information
University of Pennsylvania
Department of Anesthesiology and Critical Care
Longnecker Laboratories
319C John Morgan Building
3620 Hamilton Walk
Philadelphia, PA 19104
Department of Anesthesiology and Critical Care
Longnecker Laboratories
319C John Morgan Building
3620 Hamilton Walk
Philadelphia, PA 19104
Office: 267-544-9481
Education:
N/A
Exeter College, Oxford University, 2002.
BA (Biology and History)
Williams College, 2003.
MD (Medicine)
Columbia University, 2008.
Permanent linkN/A
Exeter College, Oxford University, 2002.
BA (Biology and History)
Williams College, 2003.
MD (Medicine)
Columbia University, 2008.
Selected Publications
Diego G Dávila, Andrew McKinstry-Wu, Max B Kelz, Alex Proekt : The administration of ketamine is associated with dose-dependent stabilization of cortical dynamics in humans. J Neurosci April 2025.Andrew McKinstry-Wu, Alex Proekt, Max Kelz: Responsiveness at Steady-State Xenon is Consolidated and Varies Over Time in Humans. Association of University Anesthesiologists Annual Meeting March 2025.
J Soohoo, A Mandel, A McKinstry-Wu: MAC Redefined: Individual Stochastic Fluctuations in Response to Noxious Stimuli at Population EC50 in Mice. International Anesthesia Research Society Annual Meeting March 2025.
Andrew McKinstry-Wu, Alex Proekt, Max Kelz: Individual Responsiveness is Both Consolidated and Varies Over Time in Humans at Constant Inhaled Xenon Concentration. Consciousness, Anesthesia, and Evolutionary Biology Gordon Research Conference January 2025.
Andrew McKinstry-Wu, Max Kelz: Reanimation of Rodents: An Animal Model for Cognitive Recovery from Anaesthesia. British Journal of Anaesthesia In Press 2025.
Panagiotis Fotiadis, Andrew R. McKinstry-Wu, Sarah M. Weinstein, Philip A. Cook, Mark Elliott, Matthew Cieslak, Jeffrey T. Duda, Theodore D. Satterthwaite, Russell T. Shinohara, Alexander Proekt, Max B. Kelz, John A. Detre, Dani S. Bassett: Changes in brain connectivity and neurovascular dynamics during dexmedetomidine-induced loss of consciousness. BioRxiv October 2024 Notes: Preprint publication while under review at other journal doi: https://doi.org/10.1101/2024.10.04.616650
Sophia Koutsogiannaki, Panop Limratana, Weiming Bu, Wiriya Maisat, Andrew McKinstry-Wu, Xiaohui Han, Umeharu Ohto, Roderic G Eckenhoff, Sulpicio G Soriano, Koichi Yuki : Dexmedetomidine directly binds to and inhibits Toll-like receptor 4 International Immunopharmacology(141), August 2024.
Andrew McKinstry-Wu, C. Will Carspecken, David Camacho, Woo Byun, George Mashour, Michael Avidan, John Woo, Alex Proekt, Max Kelz : Evidence for Anesthetic Hysteresis in Humans. Association of University Anesthesiologists Annual Meeting April 2024 Notes: poster presentation.
Wasilczuk AZ, Rinehart C, Aggarwal A, Stone ME, Mashour GA, Avidan MS, Kelz MB, Proekt A; ReCCognition Study Group.: Hormonal basis of sex differences in anesthetic sensitivity. Proc Natl Acad Sci U S A 121(3), January 2024.
Andrew McKinstry-Wu, Max Kelz: One node among many: sevoflurane-induced hypnosis and the challenge of an integrative network-level view of anaesthetic action British Journal of Anaesthesia November 2023.