Andrew McKinstry-Wu, MD
Assistant Professor of Anesthesiology and Critical Care at the Hospital of the University of Pennsylvania
Attending Anesthesiologist, Hospital of the University of Pennsylvania
Faculty Member, Center for Sleep and Circadian Biology
Faculty Member, Neuroscience of Unconsciousness and Reanimation Research Alliance
Department: Anesthesiology and Critical Care
Contact information
University of Pennsylvania
Department of Anesthesiology and Critical Care
Longnecker Laboratories
319C John Morgan Building
3620 Hamilton Walk
Philadelphia, PA 19104
Department of Anesthesiology and Critical Care
Longnecker Laboratories
319C John Morgan Building
3620 Hamilton Walk
Philadelphia, PA 19104
Office: 267-544-9481
Education:
N/A
Exeter College, Oxford University, 2002.
BA (Biology and History)
Williams College, 2003.
MD (Medicine)
Columbia University, 2008.
Permanent linkN/A
Exeter College, Oxford University, 2002.
BA (Biology and History)
Williams College, 2003.
MD (Medicine)
Columbia University, 2008.
Selected Publications
Diego G Dávila, Andrew McKinstry-Wu, Max B Kelz, Alex Proekt : The administration of ketamine is associated with dose-dependent stabilization of cortical dynamics in humans. J Neurosci April 2025.Andrew McKinstry-Wu, Alex Proekt, Max Kelz: Individual Responsiveness is Both Consolidated and Varies Over Time in Humans at Constant Inhaled Xenon Concentration. Consciousness, Anesthesia, and Evolutionary Biology Gordon Research Conference January 2025.
Panagiotis Fotiadis, Andrew R. McKinstry-Wu, Sarah M. Weinstein, Philip A. Cook, Mark Elliott, Matthew Cieslak, Jeffrey T. Duda, Theodore D. Satterthwaite, Russell T. Shinohara, Alexander Proekt, Max B. Kelz, John A. Detre, Dani S. Bassett: Changes in brain connectivity and neurovascular dynamics during dexmedetomidine-induced loss of consciousness. BioRxiv October 2024 Notes: Preprint publication while under review at other journal doi: https://doi.org/10.1101/2024.10.04.616650
Sophia Koutsogiannaki, Panop Limratana, Weiming Bu, Wiriya Maisat, Andrew McKinstry-Wu, Xiaohui Han, Umeharu Ohto, Roderic G Eckenhoff, Sulpicio G Soriano, Koichi Yuki : Dexmedetomidine directly binds to and inhibits Toll-like receptor 4 International Immunopharmacology(141), August 2024.
Andrew McKinstry-Wu, C. Will Carspecken, David Camacho, Woo Byun, George Mashour, Michael Avidan, John Woo, Alex Proekt, Max Kelz : Evidence for Anesthetic Hysteresis in Humans. Association of University Anesthesiologists Annual Meeting April 2024 Notes: poster presentation.
Wasilczuk AZ, Rinehart C, Aggarwal A, Stone ME, Mashour GA, Avidan MS, Kelz MB, Proekt A; ReCCognition Study Group.: Hormonal basis of sex differences in anesthetic sensitivity. Proc Natl Acad Sci U S A 121(3), January 2024.
Andrew McKinstry-Wu, Max Kelz: One node among many: sevoflurane-induced hypnosis and the challenge of an integrative network-level view of anaesthetic action British Journal of Anaesthesia November 2023.
Sophia Linguiti1, Jacob W. Vogel, Valerie J. Sydnor, Adam Pines, Nick Wellman, Allan Basbaum, Claudia R. Eickhoff, Simon B. Eickhoff, Robert R. Edwards, Bart Larsen, Andrew McKinstry-Wu, J. Cobb Scott, David R. Roalf Vaishnavi Sharma, Eric C. Strain, Gregory Corder, Robert H. Dworkin & Theodore D. Satterthwaite : Functional imaging studies of acute administration of classic psychedelics, ketamine, and MDMA: Methodological limitations and convergent results. Neuroscience and Biobehavioral Reviews 154, November 2023.
A McKinstry-Wu, T Jiang, K Ayensu, N Frick: "Effects of Adrenergic Signalling on Anesthetic Sensitivity and Resistance to State Transition in Mice" in: Abstracts From the 51st Annual Meeting of the Society for Neuroscience in Anesthesiology and Critical Care, September 8-10, 2023. J Neurosurg Anesthesiol 35(4): 36-e62, October 2023.
Renyu Liu, John Grothusen, Thomas T. Joseph, Andrew McKinstry-Wu: Interaction of Fentanyl with Alpha 2B Adrenergic Receptor. Translational Perioperative and Pain Medicine 10(2), June 2023.