Theodore W. Laetsch, MD
Associate Professor of Pediatrics (Oncology) at the Children's Hospital of Philadelphia
Attending Physician, Division of Oncology, Children's Hospital of Philadelphia
Inaugural Director, Very Rare Malignant Tumors Program, Children's Hospital of Philadelphia
Director, Developmental Therapeutics Program, Children's Hospital of Philadelphia
Co-Leader, Pediatric Oncology Program, Abramson Cancer Center, University of Pennsylvania
Department: Pediatrics
Contact information
Children's Hospital of Philadelphia
HUB for Clinical Collaboration
3500 Civic Center Blvd; Office 3527
Philadelphia, PA 19104
HUB for Clinical Collaboration
3500 Civic Center Blvd; Office 3527
Philadelphia, PA 19104
Email:
laetscht@chop.edu
laetscht@chop.edu
Publications
Education:
BS (Agriculture and Biosystems Engineering)
University of Arizona, Tucson, 2001.
MD
University of California, San Francisco, 2005.
Permanent linkBS (Agriculture and Biosystems Engineering)
University of Arizona, Tucson, 2001.
MD
University of California, San Francisco, 2005.
Selected Publications
Gaze MN, Handkiewicz-Junak D, Hladun R, Laetsch TW, Sorge C, Sparks R, Wan S, Ceraulo A, Kluczewska-Galka A, Gámez-Cenzano C, States LJ, El Khouli R, Aimone P, Perraud K, Kollar G, Khanshan F, Blumenstein L, Brouri F, Giraudet AL: Safety and dosimetry of [177Lu]Lu-DOTA-TATE in adolescent patients with somatostatin receptor-positive gastroenteropancreatic neuroendocrine tumours, or pheochromocytomas and paragangliomas: Primary analysis of the Phase II NETTER-P study. Eur J Nucl Med Mol Imaging Page: doi: 10.1007/s00259-025-07246-7, Apr 2025.Schraw JM, Tark JY, Desrosiers TA, Chambers TM, Shumate CJ, Nembhard WN, Yazdy MM, Nestoridi E, Malone MFW, Laetsch TW, Widemann BC, Janitz AE, Tanner JP, Kirby RS, Salemi JL, Spector LG, Huff CD, Plon SE, Lupo PJ: Risk of carcinomas among children and adolescents with birth defects. Cancer Epidemiology 95(102748), Apr 2025 Notes: doi: 10.1016/j.canep.2025.102748.
Mascarenhas L, DuBois SG, Albert CM, Bielack S, Orbach D, Federman N, Geoerger B, Nagasubramanian R, Zhang Y, Chisholm J, Gallego Melcon S, Goto H, Morgenstern DA, Owens C, Pappo AS, Perreault S, Schulte JH, Shukla N, Zwaan CM, Neu N, Bernard-Gauthier V, De La Cuesta E, van Tilburg CM, Laetsch TW: Elective Discontinuation of Larotrectinib in Pediatric Patients With TRK Fusion Sarcomas and Related Mesenchymal Tumors. Journal of Clinical Oncology 43(10): 1180-1187, April 2025 Notes: doi: 10.1200/JCO.24.00848.
Kothari R, Donner JR, Balakrishnan K, Hartman G; Pediatric Thyroid Program Workgroup:; Alazraki A, Antal Z, Bauer A, Chelius D, Cherella C, Dahl JP, Dimachkieh A, Fox LA, Helmig S, Jiang W, Kazahaya K, Laetsch TW, Lodish M, Mahajan P, Parsons L, Prickett K, Quintanilla-Dieck L, Rastatter J, Rothstein DH, Simons J, Sheyn A, Wagner A, Waguespack SG, Wasserman JD, Wassner AJ, Seeley H, Meister KD: Composition and Priorities of Multidisciplinary Pediatric Thyroid Programs: A Consensus Statement. Thyroid 34(4): 346-356, Apr 2025 Notes: DOI: 10.1089/thy.2024.0496.
Laetsch TW, Voss S, Ludwig K, Hall D, Barkauskas DA, DuBois SG, Ronan J, Rudzinski ER, Memken A, Robinson K, Sorger J, Reid JM, Bhatla T, Crompton BD, Church AJ, Fox E, Weigel BJ: Larotrectinib for Newly Diagnosed Infantile Fibrosarcoma and Other Pediatric NTRK Fusion-Positive Solid Tumors (Children's Oncology Group ADVL1823). Journal of Clinical Oncology 43(10): 1188-1197, Apr 2025 Notes: doi: 10.1200/JCO-24-01854.
Mascarenhas L, DuBois SG, Albert CM, Bielack S, Orbach D, Federman N, Geoerger B, Nagasubramanian R, Zhang Y, Chisholm J, Melcon SG, Goto H, Morgenstern DA, Owens C, Pappo AS, Perreault S, Schulte JH, Shukla N, Zwaan CM, Neu N, Bernard-Gauthier V, De La Cuesta E, van Tilburg CM, Laetsch TW: Erratum: Elective Discontinuation of Larotrectinib in Pediatric Patients With TRK Fusion Sarcomas and Related Mesenchymal Tumors. Journal of Clinical Oncology 43(10): 1046, Mar 2025 Notes: DOI: 10.1200/JCO-25-00252.
Yang AT, Lai ST, Laetsch TW, Bhatti T, Baloch Z, Surrey LF, Franco AT, Ricarte-Filho JCM, Mostoufi-Moab S, Adzick NS, Kazahaya K, Bauer AJ.: Molecular landscape and therapeutic strategies in pediatric differentiated thyroid carcinoma. Endocr Rev Page: doi: 10.1210, Mar 2025 Notes: epub ahead of print.
Yang AT, Lai ST, Laetsch TW, Bhatti T, Baloch Z, Surrey LF, Franco AT, Ricarte-Filho JCM, Mostoufi-Moab S, Adzick NS, Kazahaya K, Bauer AJ: Molecular landscape and therapeutic strategies in pediatric differentiated thyroid carcinoma. Endocrine Rev Page: bnaf003, Feb 2025 Notes: doi: 10.1210/endrev/bnaf003.
Englum BR, Sahoo S, Laetsch TW, Tiao GM, Mayorga-Carlin M, Hayssen H, Yesha Y, Sorkin JD, Lal BK: Temporal trends in pediatric cancer mortality: rare cancers lag behind more common cancers. Pediatric Hematology Oncology 42(1): 1-13, Feb 2025 Notes: doi: 10.1080/08880018.2024.2413643.
Nitsche LJ, Bontrager CE, Devlin PJ, Surrey LF, Pogoriler JE, Kreiger PA, Laetsch TW, Balis F, Fairman AS, Mattei P, Fuller SM: Complex pediatric neoplasms: The role of congenital cardiothoracic surgery. JTCVS Tech Page: 137-143, Feb 2025 Notes: DOI: 10.1016/j.xjtc.2025.01.019.