William C. Gaetz, PhD
Research Professor of Radiology
Research Scientist, Department of Radiology, Children's Hospital of Philadelphia, Philadelphia, PA, University of Pennsylvania
Senior Fellow, Center for Injury Research and Prevention (CIRP), Children's Hospital of Philadelphia Research Institute, Philadelphia, PA
Department: Radiology
Contact information
Children's Hospital of Philadelphia
Department of Radiology
3401 Civic Center Blvd.
Philadelphia, PA 19104
Department of Radiology
3401 Civic Center Blvd.
Philadelphia, PA 19104
Office: 267-426-2268
Fax: 215-590-1345
Fax: 215-590-1345
Email:
gaetzw@chop.edu
gaetzw@chop.edu
Links
World’s First Bilateral Hand Transplant on a Child Performed at The Children’s Hospital of Philadelphia
Brain-remaps-itself-child-double-hand-transplant.
CHOP/Penn medicine team is first to show massive cortical reorganization is reversible in a child
World’s First Bilateral Hand Transplant on a Child Performed at The Children’s Hospital of Philadelphia
Brain-remaps-itself-child-double-hand-transplant.
CHOP/Penn medicine team is first to show massive cortical reorganization is reversible in a child
Education:
BA (Psychology)
Simon Fraser University, Burnaby, B.C., Canada, 1994.
PhD (Experimental Psychology)
McMaster University, Hamilton, Ontario, Canada, 2002.
Permanent linkBA (Psychology)
Simon Fraser University, Burnaby, B.C., Canada, 1994.
PhD (Experimental Psychology)
McMaster University, Hamilton, Ontario, Canada, 2002.
Description of Research Expertise
I am in interested in assessing the functional significance of cortical oscillations in children using magnetoencephalography (MEG). Increasingly, I am using a multimodal approach where cortical oscillations are interpreted in the context of associated structural (MRI) and molecular (MRS GABA) measures. Results from normative developmental studies are used to detail age dependent change as well as for the interpretation of clinical findings in paediatric populations such as Autism, Friedreich Ataxia and Epilepsy.Recent work also has focused on somatosensory and motor plasticity following bilateral hand transplantation.
Selected Publications
Georgiou-Karistianis, N., Corben, L. A., Lock, E. F., Bujalka, H., Adanyeguh, I., Gaetz, W.: Neuroimaging biomarkers for Friedreich ataxia: A cross-sectional analysis of the TRACK-FA study. Annals of Neurology May 2025 Notes: Accepted publication as of May 2025.Roberts TPL, Birnbaum C, Bloy L, Gaetz W.: Beyond sensitivity: what are the enabling opportunities of OPM-MEG? Frontiers in medical technology 7, January 2025 Notes: DOI: 10.3389/fmedt.2025.1515548.
Roberts TPL, Gaetz W, Birnbaum C, Bloy L, Berman JI.: Towards biomarkers for autism spectrum disorder: Contributions of magnetoencephalography (MEG). Advances in neurobiology. Javitt, D.C., McPartland, J.C. (eds) Neurophysiologic Biomarkers in Neuropsychiatric Disorders (eds.). 40: 455-489, November 2024 Notes: Chapter, https://doi.org/10.1007/978-3-031-69491-2_16
Rhodes E, Gaetz W, Marsden J, Hall SD.: Post-Movement Beta Synchrony Inhibits Cortical Excitability. Brain sciences 14(10): 970, September 2024 Notes: DOI: 10.3390/brainsci14100970.
Shiraishi DH, Saha S, Adanyeguh IM, Cocozza S, Corben LA, Deistung A, Delatycki MB, Dogan I, Gaetz W, Georgiou-Karistianis N, Graf S, Grisoli M, Henry PG, Jarola GM, Joers JM, Langkammer C, Lenglet C, Li J, Lobo CC, Lock EF, Lynch DR, Mareci TH, Martinez ARM, Monti S, Nigri A, Pandolfo M, Reetz K, Roberts TPL, Romanzetti S, Rudko DA, Scaravilli A, Schulz JB, Subramony SH, Timmann D, Franca MC, Harding IH, Rezende TJR: Automated dentate nucleus segmentation from QSM images using deep learning. medRxiv 17, June 2024 Notes: https://doi.org/10.1101/2024.06.17.24308662.
Gaetz W, Furlong P, Amaral S, Vossough A, Schwartz E, Roberts TPL, Levin LS. : Somatosensory and motor representations following bilateral transplants of the hands: A 6-year longitudinal case report on the first successful pediatric bilateral hand transplant patient. Brain research(1804), 148262, April 2023 Notes: DOI: 10.1016/j.brainres.2023.148262; This is not a Case Report as listed in PubMed.
Walshe E, Roberts TPL, Ward McIntosh C, Winston F, Romer D, Gaetz W: An event-based magnetoencephalography study of simulated driving: Establishing a novel paradigm to probe the dynamic interplay of executive and motor function. Human brain mapping 44(5): 2109-2121, April 2023 Notes: DOI: 10.1002/hbm.26197.
Seedat, Z. A., Rier, L., Gascoyne, L. E., Cook, H., Woolrich, M. W., Quinn, A. J., Roberts, T., Furlong, P. L., Armstrong, C., St Pier, K., Mullinger, K. J., Marsh, E. D., Brookes, M. J., & Gaetz, W.: Mapping Interictal activity in epilepsy using a hidden Markov model: A magnetoencephalography study. Human brain mapping 44(1): 66-81, January 2023 Notes: DOI: 10.1002/hbm.26118.
Maldjian, J. A., Lee, R., Jordan, J., Davenport, E. M., Proskovec, A. L., Wintermark, M., Stufflebeam, S., Anderson, J., Mukherjee, P., Nagarajan, S. S., Ferrari, P., Gaetz, W., Schwartz, E., & Roberts, T. P. L.: ACR White Paper on Magnetoencephalography and Magnetic Source Imaging: A Report from the ACR Commission on Neuroradiology. AJNR. American journal of neuroradiology 43(12): E46-E53, December 2022 Notes: DOI: 10.3174/ajnr.A7714.
Nellie Georgiou-Karistianis, Louise A. Corben, Kathrin Reetz, Isaac M. Adanyeguh, Manuela Corti, Dinesh K. Deelchand, Martin B. Delatycki, Imis Dogan, Rebecca Evans, Jennifer Farmer, Marcondes C. França, William Gaetz, Ian H. Harding, Karen S. Harris, Steven Hersch, Richard Joules, James J. Joers, Michelle L. Krishnan, Michelle Lax, Eric F. Lock, David Lynch, Thomas Mareci, Sahan Muthuhetti Gamage, Massimo Pandolfo, Marina Papoutsi, Thiago Rezende, Timothy P.L. Roberts, Jens T. Rosenberg, Sandro Romanzetti Jörg B. Schulz, Traci Schilling, Adam Schwarz, Sub Subramony, Bert Yao, Stephen Zicha, Christophe Lenglet and Pierre-Gilles Henry: A natural history study to track brain and spinal cord changes in individuals with Friedreich’s ataxia: TRACK-FA study protocol. PLoS ONE 11(17): e0269649, November 2022 Notes: eCollection; DOI: 10.1371/journal.pone.0269649.