William C. Gaetz, PhD

faculty photo
Research Associate Professor of Radiology
Research Scientist, Department of Radiology, Children's Hospital of Philadelphia, Philadelphia, PA, University of Pennsylvania
Senior Fellow, Center for Injury Research and Prevention (CIRP), Children's Hospital of Philadelphia Research Institute, Philadelphia, PA
Department: Radiology

Contact information
Children's Hospital of Philadelphia
Department of Radiology
3401 Civic Center Blvd.
Philadelphia, PA 19104
Office: 267-426-2268
Fax: 215-590-1345
BA (Psychology)
Simon Fraser University, Burnaby, B.C., Canada, 1994.
PhD (Experimental Psychology)
McMaster University, Hamilton, Ontario, Canada, 2002.
Permanent link
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Description of Research Expertise

I am in interested in assessing the functional significance of cortical oscillations in children using magnetoencephalography (MEG). Increasingly, I am using a multimodal approach where cortical oscillations are interpreted in the context of associated structural (MRI) and molecular (MRS GABA) measures. Results from normative developmental studies are used to detail age dependent change as well as for the interpretation of clinical findings in paediatric populations such as Autism, Friedreich Ataxia and Epilepsy.

Recent work also has focused on somatosensory and motor plasticity following bilateral hand transplantation.

Selected Publications

Walshe E, Roberts TPL, Ward McIntosh C, Winston F, Romer D, Gaetz W: An event-based magnetoencephalography study of simulated driving: Establishing a novel paradigm to probe the dynamic interplay of executive and motor function. Human brain mapping 44(5): 2109-2121, April 2023 Notes: DOI: 10.1002/hbm.26197.

Gaetz, W., Furlong, P., Amaral, S., Vossough, A., Schwartz, E., Roberts, T. P. L., Levin, L. S.: Somatosensory and motor representations following bilateral transplants of the hands: A 6-year longitudinal case report on the first successful pediatric bilateral hand transplant patient. Brain research(1804), 148262, April 2023 Notes: DOI: 10.1016/j.brainres.2023.148262; This is not a Case Report as listed in PubMed; Online ahead of print as of August 2023.

Seedat, Z. A., Rier, L., Gascoyne, L. E., Cook, H., Woolrich, M. W., Quinn, A. J., Roberts, T., Furlong, P. L., Armstrong, C., St Pier, K., Mullinger, K. J., Marsh, E. D., Brookes, M. J., & Gaetz, W.: Mapping Interictal activity in epilepsy using a hidden Markov model: A magnetoencephalography study. Human brain mapping 44(1): 66-81, January 2023 Notes: DOI: 10.1002/hbm.26118.

Maldjian, J. A., Lee, R., Jordan, J., Davenport, E. M., Proskovec, A. L., Wintermark, M., Stufflebeam, S., Anderson, J., Mukherjee, P., Nagarajan, S. S., Ferrari, P., Gaetz, W., Schwartz, E., & Roberts, T. P. L.: ACR White Paper on Magnetoencephalography and Magnetic Source Imaging: A Report from the ACR Commission on Neuroradiology. AJNR. American journal of neuroradiology 43(12): E46-E53, December 2022 Notes: DOI: 10.3174/ajnr.A7714.

Nellie Georgiou-Karistianis, Louise A. Corben, Kathrin Reetz, Isaac M. Adanyeguh, Manuela Corti, Dinesh K. Deelchand, Martin B. Delatycki, Imis Dogan, Rebecca Evans, Jennifer Farmer, Marcondes C. França, William Gaetz, Ian H. Harding, Karen S. Harris, Steven Hersch, Richard Joules, James J. Joers, Michelle L. Krishnan, Michelle Lax, Eric F. Lock, David Lynch, Thomas Mareci, Sahan Muthuhetti Gamage, Massimo Pandolfo, Marina Papoutsi, Thiago Rezende, Timothy P.L. Roberts, Jens T. Rosenberg, Sandro Romanzetti Jörg B. Schulz, Traci Schilling, Adam Schwarz, Sub Subramony, Bert Yao, Stephen Zicha, Christophe Lenglet and Pierre-Gilles Henry: A natural history study to track brain and spinal cord changes in individuals with Friedreich’s ataxia: TRACK-FA study protocol. PLoS ONE 11(17): e0269649, November 2022 Notes: eCollection; DOI: 10.1371/journal.pone.0269649.

Gaetz, W., Graci, V., Falciani, C., Sanders, O., & Prosser, L. A.: A MEG compatible, interactive IR game paradigm for the study of visuomotor reach-to-target movements in young children and clinical populations: The Target-Touch Motor Task. Journal of neuroscience methods 380: 109675, October 2022 Notes: DOI: 10.1016/j.jneumeth.2022.109675.

Waldman, A. T., Sollee, J. R., Datta, R., Lavery, A. M., Liu, G., Aleman, T. S., Banwell, B. L., & Gaetz, W. C: Structural correlates of atypical visual and motor cortical oscillations in pediatric-onset multiple sclerosis. Human brain mapping 41(15): 4299-4313, October 2020 Notes: DOI: 10.1002/hbm.25126.

Gaetz W, Papadelis C, Wilson TW: Clinical Motor Mapping with Magnetoencephalography: Historical Approaches, Challenges, and Recommendations for Best Practice. Fifty Years of Magnetoencephalography: Beginnings, Technical Advances, and Applications. Andy Papanicolau, Timothy P.L. Roberts, James W. Wheless (eds.). Oxford University Press, Page: 211-224, August 2020 Notes: Chapter 15; DOI: 10.1093/oso/9780190935689.003.0015.

Gaetz, W., Rhodes, E., Bloy, L., Blaskey, L., Jackel, C. R., Brodkin, E. S., Waldman, A., Embick, D., Hall, S., & Roberts, T: Evaluating motor cortical oscillations and age-related change in autism spectrum disorder. NeuroImage 207: 116349, February 2020 Notes: DOI: 10.1016/j.neuroimage.2019.116349.

Gofshteyn, J. S., Le, T., Kessler, S., Kamens, R., Carr, C., Gaetz, W., Bloy, L., Roberts, T., Schwartz, E. S., & Marsh, E. D: Synthetic aperture magnetometry and excess kurtosis mapping of Magnetoencephalography (MEG) is predictive of epilepsy surgical outcome in a large pediatric cohort. Epilepsy research 155(106151), September 2019 Notes: DOI: 10.1016/j.eplepsyres.2019.106151.

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Last updated: 08/29/2023
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