William C. Gaetz, PhD

faculty photo
Research Associate Professor of Radiology
Research Scientist, Department of Radiology, Children's Hospital of Philadelphia, Philadelphia, PA, University of Pennsylvania
Senior Fellow, Center for Injury Research and Prevention (CIRP), Children's Hospital of Philadelphia Research Institute, Philadelphia, PA
Department: Radiology

Contact information
Children's Hospital of Philadelphia
Department of Radiology
014A Seashore House
3401 Civic Center Blvd.
Philadelphia, PA 19104
Office: 267-426-2268
Fax: 215-590-1345
BA (Psychology)
Simon Fraser University, Burnaby, B.C., Canada, 1994.
PhD (Experimental Psychology)
McMaster University, Hamilton, Ontario, Canada, 2001.
Permanent link
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Description of Research Expertise

I am in interested in assessing the functional significance of cortical oscillations in children using magnetoencephalography (MEG). Increasingly, I am using a multimodal approach where cortical oscillations are interpreted in the context of associated structural (MRI) and molecular (MRS GABA) measures. Results from normative developmental studies are used to detail age dependent change as well as for the interpretation of clinical findings in paediatric populations such as Autism, Friedreich Ataxia and Epilepsy.

Recent work also has focused on somatosensory and motor plasticity following bilateral hand transplantation.

Selected Publications

Walshe, E. A., Roberts, T. P. L., Ward McIntosh, C., Winston, F. K., Romer, D., & Gaetz, W: An event-based magnetoencephalography study of simulated driving: Establishing a novel paradigm to probe the dynamic interplay of executive and motor function. Human brain mapping January 2023 Notes: DOI: 10.1002/hbm.26197; Online ahead of print as of January 2023.

Gaetz, W., Furlong, P., Amaral, S., Vossough, A., Schwartz, E., Roberts, T. P. L., Levin, L. S.: Somatosensory and motor representations following bilateral transplants of the hands: A 6-year longitudinal case report on the first successful pediatric bilateral hand transplant patient. Brain Research Jan 2023 Notes: Accepted for publication as of January 2023; Manuscript BRAINRES-D-22-01127R2.

Elizabeth A. Walshe, PhD, Timothy P.L. Roberts, PhD, Chelsea Ward McIntosh, MS, Flaura K. Winston PhD, Dan Romer, PhD, William Gaetz, PhD: An Event-Based MEG Study of Simulated Driving: Establishing a Novel Paradigm to Probe the Dynamic Interplay of Executive and Motor Function. Human brain mapping January 2023 Notes: DOI: 10.1002/hbm.26197; Online ahead of print as of January 2023.

Joseph Maldjian, MD; Roland Lee, MD; John Jordan, MD, MPP; Elizabeth M. Davenport, PhD; Amy L. Proskovec, PhD; Max Wintermark, MD; Steven Stufflebeam, MD, PhD; Jeff Anderson, MD, PhD; Pratik Mukherjee, MD PhD; Srikantan S. Nagarajan, PhD; Paul Ferrari, PhD; William Gaetz, PhD; Erin Schwartz, MD; Timothy P.L. Roberts, PhD: ACR White Paper on Magnetoencephalography and Magnetic Source Imaging: A Report from the ACR Commission on Neuroradiology. Journal of the American College of Radiology: JACR December 2022 Notes: DOI: 10.3174/ajnr.A7714; Online ahead of print as of December 2022.

Nellie Georgiou-Karistianis, Louise A. Corben, Kathrin Reetz, Isaac M. Adanyeguh, Manuela Corti, Dinesh K. Deelchand, Martin B. Delatycki, Imis Dogan, Rebecca Evans, Jennifer Farmer, Marcondes C. França, William Gaetz, Ian H. Harding, Karen S. Harris, Steven Hersch, Richard Joules, James J. Joers, Michelle L. Krishnan, Michelle Lax, Eric F. Lock, David Lynch, Thomas Mareci, Sahan Muthuhetti Gamage, Massimo Pandolfo, Marina Papoutsi, Thiago Rezende, Timothy P.L. Roberts, Jens T. Rosenberg, Sandro Romanzetti Jörg B. Schulz, Traci Schilling, Adam Schwarz, Sub Subramony, Bert Yao, Stephen Zicha, Christophe Lenglet and Pierre-Gilles Henry: A natural history study to track brain and spinal cord changes in individuals with Friedreich’s ataxia: TRACK-FA study protocol. PLoS ONE 11(17): e0269649, November 2022 Notes: eCollection; DOI: 10.1371/journal.pone.0269649.

Gaetz, W., Graci, V., Falciani, C., Sanders, O., & Prosser, L. A.: A MEG compatible, interactive IR game paradigm for the study of visuomotor reach-to-target movements in young children and clinical populations: The Target-Touch Motor Task. Journal of neuroscience methods 380: 109675, October 2022 Notes: DOI: 10.1016/j.jneumeth.2022.109675.

Seedat, Z. A., Rier, L., Gascoyne, L. E., Cook, H., Woolrich, M. W., Quinn, A. J., Roberts, T., Furlong, P. L., Armstrong, C., St Pier, K., Mullinger, K. J., Marsh, E. D., Brookes, M. J., & Gaetz, W.: Mapping Interictal activity in epilepsy using a hidden Markov model: A magnetoencephalography study. Human brain mapping October 2022 Notes: DOI: 10.1002/hbm.26118; Online ahead of print as of December 2022.

Walshe E, Roberts TPL, Ward McIntosh C, Winston F, Romer D, Gaetz W: An Event-Based MEG Study of Simulated Driving: Establishing a Novel Paradigm to Probe the Dynamic Interplay of Executive and Motor Oscillatory Activity. Human brain mapping August 2022 Notes: Accepted for publication as of August 2022; In-press as of November 2022.

Waldman, A. T., Sollee, J. R., Datta, R., Lavery, A. M., Liu, G., Aleman, T. S., Banwell, B. L., & Gaetz, W. C: Structural correlates of atypical visual and motor cortical oscillations in pediatric-onset multiple sclerosis. Human brain mapping 41(15): 4299-4313, October 2020 Notes: DOI: 10.1002/hbm.25126.

Gaetz W, Papadelis C, Wilson TW: Clinical Motor Mapping with Magnetoencephalography: Historical Approaches, Challenges, and Recommendations for Best Practice. Fifty Years of Magnetoencephalography: Beginnings, Technical Advances, and Applications. Andy Papanicolau, Timothy P.L. Roberts, James W. Wheless (eds.). Oxford University Press, Page: 211-224, August 2020 Notes: Chapter 15; DOI: 10.1093/oso/9780190935689.003.0015.

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Last updated: 02/21/2023
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