Nicole Jaffe, MD

faculty photo
Clinical Assistant Professor of Pediatrics (General Pediatrics)
Department: Pediatrics

Contact information
CHOP Care Network Cobbs Creek
225 Cobbs Creek Parkway
Philadelphia, PA 19139
Office: 215-476-2223
Fax: 215-476-3981
Education:
B.S. (Microbiology)
Cornell University, 2006.
M.D. (Medicine)
Boston University School of Medicine, 2010.
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Description of Clinical Expertise

Complex Care
Leukodystrophy
Autism in primary care

Selected Publications

Jeffrey M Eugene 1 2, Maria Nelson 3, Rebecca Neergaard 3, Emma Edmondson 3, Sarah Capponi 4, M Christina Herrera 1, Judy A Shea 3, Katherine Yun 1, Nicole Jaffe 1, Julie Premo 1, George Dalembert 1: Pediatrician Perspectives on Incorporating Discussion of Police Encounters Into Anticipatory Guidance for Black Youth and Their Caregivers. JAMA Pediatrics 179(3): 350-352, March 2025.

Jaffe N, Ball LJ, Evans S: Feeding and nutrition in the pediatric leukodystrophy patient. Curr Probl Pediatr Adolesc Health Care 53(1), Jan 2023.

Modesti NB, Evans SH, Jaffe N, Vanderver A, Gavazzi F: Early recognition of patients with leukodystrophies. Curr Probl Pediatr Adolesc Health Care 52(12), December 2022.

Perez G, Young L, Kravitz R, Sheehan D, Adang L, Van Haren K, Lin JL, Jaffe NN, Kuo D, Ball L, Keller J, Sank J, DiVito D, Naime S: Pulmonlogic Issues Curr Probl Pediatr Adolesc Health Care 52(12), Dec 2022.

Vanderver A, Adang L, Gavazzi F, McDonald K, Helman G, Frank DB, Jaffe N, Yum SW, Collins A, Keller SR, Lebon P, Meritet JF, Rhee J, Takanohashi A, Armangue T, Ulrick N, Sherbini O, Koh J, Peer K, Besnier C, Scher C, Boyle K, Dubbs H, Kramer-Golinkoff J, Pizzino A, Woidill S, Shults J.: Janus Kinase Inhibitors in the Aicardi-Goutieres Syndrome New England Journal of Medicine 383(10): 986-989, September 2020.

Adang, L. A., Sherbini, O., Ball, L., Bloom, M., Darbari, A., Amartino, H., DiVito, D., Eichler, F., Escolar, M., Evans, S. H., Fatemi, A., Fraser, J., Hollowell, L., Jaffe, N., Joseph, C., Karpinski, M., Keller, S., Maddock, R., Mancilla, E., McClary, B: Revised consensus statement on the preventive and symptomatic care of patients with leukodystrophies. Mol Genet Metab 122(1-2): 18-32, Sept 2017.

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Last updated: 02/06/2026
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