Nicole Jaffe, MD

faculty photo
Clinical Assistant Professor of Pediatrics (General Pediatrics)
Department: Pediatrics

Contact information
CHOP Care Network Cobbs Creek
225 Cobbs Creek Parkway
Philadelphia, PA 19139
Office: 215-476-2223
Fax: 215-476-3981
Education:
B.S. (Microbiology)
Cornell University, 2006.
M.D. (Medicine)
Boston University School of Medicine, 2010.
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Description of Clinical Expertise

Complex Care
Leukodystrophy
Autism in primary care

Selected Publications

Jeffrey M Eugene 1 2, Maria Nelson 3, Rebecca Neergaard 3, Emma Edmondson 3, Sarah Capponi 4, M Christina Herrera 1, Judy A Shea 3, Katherine Yun 1, Nicole Jaffe 1, Julie Premo 1, George Dalembert 1: Pediatrician Perspectives on Incorporating Discussion of Police Encounters Into Anticipatory Guidance for Black Youth and Their Caregivers. JAMA Pediatrics jan 2026.

Jaffe N, Ball LJ, Evans S: Feeding and nutrition in the pediatric leukodystrophy patient. Curr Probl Pediatr Adolesc Health Care jan 2023.

Jaffe, N., Ball, L. J., & Evans, S: Feeding and nutrition in the pediatric leukodystrophy patient. Current problems in pediatric and adolescent health care 2023.

Modesti NB, Evans SH, Jaffe N, Vanderver A, Gavazzi F: Early recognition of patients with leukodystrophies. Curr Probl Pediatr Adolesc Health Care 12, dec 2022.

Perez G, Young L, Kravitz R, Sheehan D, Adang L, Van Haren K, Lin JL, Jaffe NN, Kuo D, Ball L, Keller J, Sank J, DiVito D, Naime S: Pulmonlogic Issues Curr Probl Pediatr Adolesc Health Care 52(12):(101313), Dec 2022.

Modesti, N. B., Evans, S. H., Jaffe, N., Vanderver, A., & Gavazzi, F: Early recognition of patients with leukodystrophies. Current problems in pediatric and adolescent health care. Current problems in pediatric and adolescent health care, 52, 2022.

Vanderver, A. & Adang, L & Gavazzi, F & McDonald K & Helman, G & Frank, D & Jaffe, N &(…) Shults, J: Janus Kinase Inhibitors in the Aicardi-Goutieres Syndrome New England Journal of Medicine 383: 986-989, 2020.

Adang, L. A., Sherbini, O., Ball, L., Bloom, M., Darbari, A., Amartino, H., DiVito, D., Eichler, F., Escolar, M., Evans, S. H., Fatemi, A., Fraser, J., Hollowell, L., Jaffe, N., Joseph, C., Karpinski, M., Keller, S., Maddock, R., Mancilla, E., McClary, B: Revised consensus statement on the preventive and symptomatic care of patients with leukodystrophies. Molecular genetics and metabolism, 122(1-2), 18–32. https://doi.org/10.1016/j.ymgme.2017.08.006 122, 2017.

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Last updated: 08/18/2025
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