Selected Publications

Hanson D, Chi S, Braunstein S, Elhalawani H, Kool M, Filbin M, Gojo J, Plasschaert S, Margol A, Kline C, Molinaro A, Prados M, Mueller S. : PNOC031 - International Trial for Embryonal Tumor with Multilayered Rosettes. Poster presentation at: 21st International Symposium on Pediatric Neuro-Oncology; Philadelphia, Pennsylvania. June 29-July 2, 2024. June 2024.

Raber S, Hoffman C, Kline C, Mueller S, Prados M, Meyer A. : Implementing a nursing led working group within the Pediatric Neuro-Oncology Consortium (PNOC), a two-year experience and evaluation. Podium presentation at: 21st International Symposium on Pediatric Neuro-Oncology; Philadelphia, Pennsylvania. June 29-July 2, 2024. June 2024.

Franson A, Kilburn L, Cooney T, Stoller S, Reddy A, Banerjee A, Packer R, Bendel A, Skrypek M, Minturn J, ABdelbaki M, Whipple N, Chan P, Crawford J, Leary S, Waanders A, Elster J, Cohen K, George E, Pinto S, Vossough A, Kraya A, Prados M, Kline C, Nazarian J, Solomon D, Long-Boyle J, Molinaro A, Waszak S, Mueller S.: PNOC008: a pilot trial testing the Clinical Benefit of Using Molecular Profiling to Determine an Individualized Treatment Plan in Children and Young Adults with High-Grade Glioma (Excluding Diffuse Intrinsic Pontine Glioma). Poster presentation at: 21st International Symposium on Pediatric Neuro-Oncology; Philadelphia, Pennsylvania. June 29-July 2, 2024. June 2024.

Kline C*, Yu B, Knowles T, Ranavaya A, Minturn J, Banerjee A, Leary S, Abdelbaki MS, Whipple N, Goldman S, Margol A, Dabobo N, Rauschecker A, George E, Nabavizadeh A, Hoare O, Jung J, Phillips J, Prados M, Molinaro A, Gupta N, Raffel C, Cole K, Diaz A, Mueller S: PNOC005: Oncolytic measles virus for the treatment of children and young adults with recurrent medulloblastoma or atypical teratoid rhabdoid tumor. Podium presentation at: 21st International Symposium on Pediatric Neuro-Oncology June 2024.

Kline C*, Schoenfeld J*, Gajjar A, Tinkle C, Margol A, Davidson T, Bendel A, Skrypek M, Kliburn LB, Packer R, Reddy AT, Abdelbaki MS, Rubin J, Sayour E, Mitchell D, Chi S, Waanders AJ, Elster J, Baxter P, Crotty E, Cohen K, Moertel C, Franson AT, Whipple N, Bansal S, Jankovic, V, Kaul M, Paccaly A, Zhong B, Schmidt T, Lowy I, Seebach F, Liu K, Gunasti L, Morinigo D, Singh S, Shai A, Phillips J, Filbin M, Nazarian J, Catalano P, Prados M, Haas-Kogan D, Magnan H, Mueller S: A phase 1/2 study assessing safety and pharmacokinetics of cemiplimab in pediatric patients with relapsed or refractory solid or central-nervous-system tumors and safety and efficacy of cemiplimab in combination with radiotherapy in patients with newly diagnosed diffuse intrinsic pontine glioma, newly diagnosed high-grade glioma, or recurrent high-grade glioma. Poster presentation at: 21st International Symposium on Pediatric Neuro-Oncology June 2024.

Kline C, Franson A, Banerjee A, Reddy AT, Raber S, Hoffman C, Minturn J, van der Lugt J, de Vos-Kerkhof E, van Vuurden D, Gerber N, Guerreiro Stuecklin A, Kilburn LB, Elster J, Whipple N, Cohen KJ, Yalon Oren M, Gardner SL, Cluster A, Chi SN, Landi DB, McCowage G, Vo J, Resnick A, Phillips J, Bhatia A, George E, Vossough A, Nabavizadeh A, Braunstein SE, Gupta N, Prados M, Waszak SM, Boyle-Lang J, Molinaro AM, Dun MD, Koschmann CJ, Nazarian J, Mueller S: PNOC022 report: a combination therapy trial using an adaptive platform design for patients with diffuse midline glioma at initial diagnosis, post-radiation therapy, or progression. Podium presentation at: 21st International Symposium on Pediatric Neuro-Oncology June 2024.

Shatara M, Paul MR, Long-Boyle J, Meyer A, Raber S, Yeh-Nayre L, Jalkanen A, Kilburn L, Packer R, Elster J, Reddy A, Koschmann C, Kraya A, Resnick A, Prados M, Kline C, Mueller S, Wechsler-Reya R, Rubin J. : Early Insights from PNOC027: Personalized Treatment Approaches Based on Real-Time Drug Screening and Genomic Testing in Pediatric and Adolescent Patients with Recurrent Medulloblastoma. Poster presentation at: 21st International Symposium on Pediatric Neuro-Oncology; Philadelphia, Pennsylvania. June 29-July 2, 2024. June 2024.

Kline C*, Crawford J, Reddy AT, Gerber N, Guerreiro Stucklin A, Kilburn LB, Packer R, Margol A, Crotty E, Sayour E, Franson AT, Phillips J, Singh S, Hamanishi E, Lee C, Bhatia A, George E, Rauschecker A, Molinaro A, Prados M, Nazarian J,Venneti S, Wechsler-Reya R, Mueller S: PNOC016: Intratumoral pharmacokinetics and pharmacodynamic (PK/PD) results from a target validation study of a novel pan-HDAC and PI3K inhibitor, fimepinostat, in children and young adults with newly diagnosed diffuse intrinsic pontine glioma (DIPG), recurrent medulloblastoma (MB), and recurrent high-grade glioma (HGG). Podium presentation at: 21st International Symposium on Pediatric Neuro-Oncology June 2024.

Seidl K, Briamonte C, Higgins M, Hoffman C, Holtzlaw S, McHugh M, Meyer A, Rangan K, Schmus C, Strachan M, Waters K, Yeh-Nayre L, Kline C, Prados M, Mueller S, Raber S. : Exploration of correlative studies in early phase trials for pediatric central nervous system (CNS) tumors and the potential translation to clinical care. Podium presentation at: 21st International Symposium on Pediatric Neuro-Oncology; Philadelphia, Pennsylvania. June 29-July 2, 2024. June 2024.

Mueller S, Kline C, Franson A, van der Lugt J, Prados M, Waszak SM, Plasschaert SLA, Molinaro AM, Koschmann C, Nazarian J.: Rational combination platform trial design for children and young adults with diffuse midline glioma: A report from PNOC. Neuro Oncol 26: S125-S135, May 2024.