Selected Publications

Joshi N, Mueller S, Kline C. : Current clinical trials for craniopharyngiomas: what's on the horizon? J Neurooncol. Apr 2025 Notes: doi: 10.1007/s11060-024-04899-6

Erker C, Mynarek M, Simbozel M, Craig BT, Harrod VL, Cappellano AM, Cohen KJ, Lopez VS, Morales-La Madrid A, Cacciotti C, Baroni L, Salloum R, Margol AS, Michaiel G, Aguilera D, Mazewski CM, Kline CN, Finlay JL, Abdelbaki MS, Murray JC, Dorris K, Crooks B, Ginn KF, Amayiri N, Tippelt S, Fleischhack G, Tonn S, Gerber NU, Lassaletta A, Hansford JR, Khan S, Gilheeney SW, Hoffman LM, Zapotocky M, Larouche V, Shah S, Ramaswamy V, Gajjar A, Perreault S, Mueller S, Hukin J, Cheng S, Wang ZJ, Matheson K, Bailey S, Bouffet E, Clifford SC, Robinson G, Dufour C, Rutkowski S, Lafay-Cousin L. : Salvage therapies for first relapse of SHH medulloblastoma in early childhood. Neuro Oncol. Apr 2025 Notes: doi: 10.1093/neuonc/noaf092.

Karsten Nysom, Lindsay B Kilburn, Sarah E S Leary, Daniel B Landi, Evelien de Vos-Kerkhof, Sébastien Perreault, Olaf Witt, David S Ziegler, Pablo Hernáiz Driever, Andrea T Franson, Patricia A Baxter, Nicholas S Whipple, Cassie Kline, Devorah Segal, Nada Jabado, Simon Bailey, Geoffrey McCowage, Jordan R Hansford, Dong-Anh Khuong-Quang, Nicholas G Gottardo, Timothy Hassall, Jung Woo Han, Michal Yalon Oren, Susan N Chi, Jiaheng Qiu, Daniel Da Costa, Sandya Govinda Raju, Peter Manley, Darren Hargrave: Radiographic and visual response to the type II RAF inhibitor tovorafenib in children with relapsed/refractory optic pathway glioma in the FIREFLY-1 trial. Neuro Oncol February 2025 Notes: https://doi.org/10.1093/neuonc/noae274.

Ryan J Corbett, Cricket C Gullickson, Zhuangzhuang Geng, Miguel A Brown, Bo Zhang, Chuwei Zhong, Nicholas Van Kuren, Antonia Chroni, Christopher Blackden, Ammar S Naqvi, Alexa Plisiewicz, Sean McHugh, Emmett Drake, Kaitlin Lehmann, Tom B Davidson, Michael Prados, Phillip B Storm, Adam C Resnick, Angela J Waanders, Sebastian M Waszak, Sabine Mueller, Jo Lynne Rokita, Cassie Kline: Genetic ancestry superpopulations show distinct prevalence and outcomes across pediatric central nervous system tumors from the PBTA and PNOC. Neuro Oncol Jan 2025 Notes: Ref.: Ms. No. N-O-D-24-00560R3 doi: 10.1093/neuonc/noaf017.

Roberts HJ, Ravi K, Marini BL, Schepers A, Kline C, Kilburn L, Prados M, Byron SA, Sturza J, Mueller S, Koschmann C, Franson AT.: Retrospective Comparison of Targeted Anticancer Drugs Predicted by the CNS-TAP Tool Versus Those Selected by a Molecularly Driven Tumor Board in Children With DIPG. J Pediatr Hematol Oncol. Ja 2025 Notes: doi: 10.1097/MPH.0000000000002964.

Hoogendijk R, van den Broek TJM, Lee H, Mueller S, Kline C, Bianco J, Top J, de Zoete MR, Kester L, Calkoen F, van der Lugt J.: Omnigene-Gut(tm) ensures fecal microbiome stability in the pediatric population. AMB Express Dec 2024 Notes: doi: 10.1186/s13568-024-01798-x.

Wright K, Kline C, Abdelbaki MS, Sayour E, Crotty E, Raabe E, Elster J, Prados M, Haas-Kogan D, Mueller S: Decreased growth velocity in a phase 1 trial (PNOC014) of Tovorafenib in patients with recurrent or progressive MAPK-altered tumors. Neuro Oncol 26(8), November 2024.

Apps JR, Gonzalez-Meljem JM, Guiho R, Pickles JC, Prince E, Schwalbe E, Joshi N, Stone TJ, Ogunbiyi O, Chalker J, Bassey A, Otto G, Davies R, Hughes D, Brandner S, Tan E, Lee V, Hayhurst C, Kline C, Castellano S, Hankinson T, Deutschbein T, Jacques TS, Martinez-Barbera JP. : Recurrent adamantinomatous craniopharyngioma show MAPK pathway activation, clonal evolution and rare TP53-loss-mediated malignant progression. Acta Neuropathol Commun August 2024.

Beauchemin MP, Ortega M, Santacroce SJ, Robles JM, Ruiz J, Hall AG, Kahn JM, Fu C, Orjuela-Grimm M, Hillyer GC, Solomon S, Pelletier W, Montiel-Esparza R, Blazin LJ, Kline C, Seif AE, Aristizabal P, Winestone LE, Velez MC. : Clinical trial recruitment of people who speak languages other than English: a Children’s Oncology Group report. JNCI Cancer Spectr July 2024.

Hanson D, Chi S, Braunstein S, Elhalawani H, Kool M, Filbin M, Gojo Johannes, Plasschaert S, Von Hoff K, Margol A, Kline C, Molinaro A, Prados M, Mueller S.: PNOC031 - International trial for embryonal tumor with multilayered rosettes. Neuro Oncol 26(4), June 2024.