Cassie Kline, MD, MAS
Assistant Professor of Pediatrics at the Children's Hospital of Philadelphia
Director, Neuro-Oncology Clinical Research, Children’s Hospital of Philadelphia, Philadelphia, PA
Pacific Pediatric Neuro-Oncology Consortium Site PI, Children’s Hospital of Philadelphia, Philadelphia, PA
Department: Pediatrics
Contact information
Children’s Hospital of Philadelphia
The Hub for Clinical Collaboration
3500 Civic Center Blvd, Room 3591
Philadelphia, PA 19104
Philadelphia, PA 19104
The Hub for Clinical Collaboration
3500 Civic Center Blvd, Room 3591
Philadelphia, PA 19104
Philadelphia, PA 19104
Office: 267-426-6559
Email:
klinec@chop.edu
klinec@chop.edu
Education:
BA (Biology, Cum Laude)
University of Virginia, 2004.
Post-Bacc (Post-baccalaureate)
University of California, San Diego, 2006.
MD (Medicine)
University of California, San Diego, 2011.
MAS (Clinical Research )
University of California, San Francisco, 2017.
Permanent linkBA (Biology, Cum Laude)
University of Virginia, 2004.
Post-Bacc (Post-baccalaureate)
University of California, San Diego, 2006.
MD (Medicine)
University of California, San Diego, 2011.
MAS (Clinical Research )
University of California, San Francisco, 2017.
Selected Publications
Erin R Bonner, Robin Harrington, Augustine Eze, Miriam Bornhorst, Cassie N Kline, Heather Gordish-Dressman, Adam Dawood, Biswajit Das, Li Chen, Rini Pauly, P Mickey Williams, Chris Karlovich, Amanda Peach, D'andra Howell, James Doroshow, Lindsay Kilburn, Roger J Packer, Sabine Mueller, Javad Nazarian: Circulating tumor DNA sequencing provides comprehensive mutation profiling for pediatric central nervous system tumors. NPJ Precis Oncol September 2022 Notes: DOI: 10.1038/s41698-022-00306-3.Evan Cantor, Kyle Wierzbicki, Rohinton S Tarapore, Karthik Ravi, Chase Thomas, Rodrigo Cartaxo, Viveka Nand Yadav, Ramya Ravindran, Amy K Bruzek, Jack Wadden, Vishal John, Clarissa May Babila, Jessica R Cummings, Abed Rahman Kawakibi, Sunjong Ji, Johanna Ramos, Alyssa Paul, Dustin Walling, Marcia Leonard 1, Patricia Robertson, Andrea Franson, Rajen Mody, Hugh J L Garton, Sriram Venneti, Yazmin Odia, Cassie Kline, Nicholas A Vitanza, Soumen Khatua, Sabine Mueller, Joshua E Allen, Sharon L Gardner, Carl Koschmann : Serial H3K27M cell-free tumor DNA (cf-tDNA) tracking predicts ONC201 treatment response and progression in diffuse midline glioma. Neuro Oncol August 2022 Notes: DOI: 10.1093/neuonc/noac030.
Cassie Kline, Payal Jain, Lindsay Kilburn, Erin R Bonner, Nalin Gupta, John R Crawford, Anu Banerjee, Roger J Packer, Javier Villanueva-Meyer, Tracy Luks, Yalan Zhang, Madhuri Kambhampati, Jie Zhang, Sridevi Yadavilli, Bo Zhang, Krutika S Gaonkar, Jo Lynne Rokita, Adam Kraya, John Kuhn, Winnie Liang, Sara Byron, Michael Berens, Annette Molinaro, Michael Prados, Adam Resnick, Sebastian M Waszak, Javad Nazarian, Sabine Mueller : Upfront biology-guided therapy in diffuse intrinsic pontine glioma: therapeutic, molecular, and biomarker outcomes from PNOC003. Clin Cancer Res July 2022 Notes: DOI: 10.1158/1078-0432.CCR-22-0803.
Cassie Kline, Schuyler Stoller, Lennox Byer, David Samuel, Janine M Lupo, Melanie A Morrison, Andreas M Rauschecker, Pierre Nedelec, Walter Faig, Dena B Dubal, Heather J Fullerton, Sabine Mueller: An Integrated Analysis of Clinical, Genomic, and Imaging Features Reveals Predictors of Neurocognitive Outcomes in a Longitudinal Cohort of Pediatric Cancer Survivors, Enriched with CNS Tumors (Rad ART Pro). Front Oncol June 2022 Notes: DOI: 10.3389/fonc.2022.874317.
Cassie Kline, Schuyler Stoller, Lennox Byer, David Samuel, Janine M Lupo, Melanie Anne Morrison, Andreas M Rauschecker, Pierre Nedelec, Walter Faig, Dena B Dubal, Heather J Fullerton, Sabine Mueller: An integrated analysis of clinical, genomic, and imaging reveals predictors of neurocognitive outcomes in a longitudinal cohort of pediatric cancer survivors, enriched with CNS tumors (Rad ART Pro. Frontiers in Oncology June 2022 Notes: doi.org/10.3389/fonc.2022.874317.
Cassie Kline , Payal Jain , Lindsay B. Kilburn , Erin R Bonner , Nalin Gupta , John R Crawford , Anuradha Banerjee , Roger Packer , Javier E Villanueva-Meyer , Tracy Luks , Yalan Zhang , Madhuri Kambhampati , Jie Zhang , Sridevi Yadavilli , Bo Zhang , Krutika S Gaonkar , Jo Lynne Rokita , Adam Kraya , John G Kuhn , Winnie S Liang , Sara A. Byron , Michael E. Berens , Annette M. Molinaro , Michael Prados , Adam C Resnick , Dr. Sebastian M Waszak , Javad Nazarian, Sabine Mueller: Upfront biology-guided therapy in diffuse intrinsic pontine glioma: therapeutic, molecular, and biomarker outcomes from PNOC003. Clinical Cancer Research June 2022 Notes: Provisionally accepted.
Jenny Ruiz, Alexandra N. Welch, Danielle Clerico, Susan E. McClory, Mia Benson Smith, Suzanne P. MacFarland, Lisa Wray, Cassie Kline: Implementing a Diversity, Equity and Antiracism Curriculum in a Single Institution Cancer Center. Pediatric Academic Societies April 2022.
Evan Cantor, Kyle Wierzbicki, Rohinton S Tarapore, Karthik Ravi, Chase Thomas, Rodrigo Cartaxo, Viveka Nand Yadav, Ramya Ravindran, Amy K Bruze k, Jack Wadden, Vishal John, Clarissa May Babila, Jessica R Cummings, Abed Rahman Kawakibi, Sunjong Ji, Johanna Ramos, Alyssa Paul, Dustin Walling, Marcia Leonard, Patricia Robertson, Andrea Franson, Rajen Mody, Hugh J L Garton, Sriram Venetti, Yazmin Odia, Cassie Kline, Nicholas A Vitanza 7, Soumen Khatua, Sabine Mueller, Joshua E Allen, Sharon Gardner 10, Carl Koschmann : Serial H3K27M cell-free tumor DNA (cf-tDNA) tracking predicts ONC201 treatment response and progression in diffuse midline glioma. Neuro Oncol Feb 2022 Notes: DOI: 10.1093/neuonc/noac030.
Emily Marshall, Sylvia Cheng MD BHSc MScCH, Julia Crowley MD, Shana McCormack MD MTR, Brian Rood MD, Todd Hankinson MD, Michael DeCuypere MD PhD, Sandy Lam MD MBA, Stewart Goldman MD, Svenja Boekhoff, Herman Muller MD, Ryan Velasco, Philip B Storm MD, Adam Resnick PhD, Michael Prados MD, Sabine Mueller MD PhD, Cassie Kline MD MAS, Fatema Malbari MD: Clinical management and functional and survival outcomes in pediatric craniopharyngioma, a patient and family perspective. Poster presentation at: International Symposium on Pediatric Neuro-Oncology; Hamburg, Germany. June 13-15, 2022. 2022.
Cassie Kline, Adam Resnick, Michael Prados, Sabine Mueller: Disease-specific working groups within the Pacific Pediatric Neuro-Oncology Consortium (PNOC) and Children’s Brain Tumor Network (CBTN) facilitate multi-disciplinary collaboration and translation of innovative strategies in pediatric neuro-oncology Poster presentation at: International Symposium on Pediatric Neuro-Oncology; Hamburg, Germany. June 13-15, 2022. 2022.