Joseph W. Rossano, MD, MS, MHCM

Professor of Pediatrics (Cardiology) at the Children's Hospital of Philadelphia
Core Faculty, Center for Pediatric Clinical Effectiveness, Children’s Hospital of Philadelphia Research Institute
Core Faculty, Cardiovascular Outcomes, Quality, and Evaluative Research Center, University of Pennsylvania
Senior Fellow, Leonard Davis Institute of Health Care Economics, University of Pennsylvania
Chief, Division of Cardiology, Children's Hospital of Philadelphia
Co-Executive Director, The Cardiac Center, Children's Hospital of Philadelphia
Jennifer Terker Endowed Chair in Pediatric Cardiology, Children's Hospital of Philadelphia
Department: Pediatrics
Contact information
The Children’s Hospital of Philadelphia
Division of Cardiology
34th Street and Civic Center Boulevard
Room 8NW81
Philadelphia, PA 19104
Division of Cardiology
34th Street and Civic Center Boulevard
Room 8NW81
Philadelphia, PA 19104
Office: 267-425-6116
Fax: 215-590-1340
Fax: 215-590-1340
Education:
B.S. (Zoology)
Northern Arizona University, 1996.
M.D. (Doctor of Medicine )
The University of Arizona College of Medicine, 2001.
M.S. (Clinical Research)
Baylor College of Medicine, 2011.
M.H.C.M (Health Care Management)
Harvard T.H. Chan School of Public Health, 2022.
Permanent linkB.S. (Zoology)
Northern Arizona University, 1996.
M.D. (Doctor of Medicine )
The University of Arizona College of Medicine, 2001.
M.S. (Clinical Research)
Baylor College of Medicine, 2011.
M.H.C.M (Health Care Management)
Harvard T.H. Chan School of Public Health, 2022.
Selected Publications
Butters A, Arnott C, Sweeting J, Claggett B, Cuomo A, Abrams D, Ashley EA, Day SM, Helms AS, Lampert R, Lin K, Michels M, Miller EM, Olivotto I, Owens A, Parikh VN, Pereira AC, Rossano JW, Ryan TD, Saberi S, Stendahl JC, Ware JS, Atherton J, Semsarian C, Lakdawala NK, Ho CY, Ingels J: Sex-specific clinical and genetic factors associated with adverse outcomes in hypertrophic cardiomyopathy. Circulation: Genomic and Precision Medicine. In Press, 2025Griffiths ER, Profsky MP, Mokshagundam D, Boucek K, Amdani S, Davies RR, Monge MC, Morales DL, Rossano JW, Jacobs JP, Kirklin JK, Koehl D, Cantor R, Peng DM; Pedimacs Investigators: Eighth annual Society of Thoracic Surgeons Pedimacs report. The Annals of Thoracic Surgery 2025 Notes: In Press.
Goldfarb SB, Burstein DS, Rossano JW: Heart-Lung and Lung Transplantation. Nelson Textbook of Pediatrics, 22nd ed. Kliegman RM. St. Geme III JW, Blum NJ, Tasker RC, Wilson KM, Schuh Am, Mack CL (eds.). Elsevier, Page: 2905-2906, 2025.
Burstein DS, Rossano JW: Cardiogenic Shock. Nelson Textbook of Pediatrics, 22nd ed. Kliegman RM. St. Geme III JW, Blum NJ, Tasker RC, Wilson KM, Schuh Am, Mack CL (eds.). Elsevier, Page: 2901-2902, 2025.
Burstein DS, Rossano JW: Heart Failure. Nelson Textbook of Pediatrics, 22nd ed. Kliegman RM. St. Geme III JW, Blum NJ, Tasker RC, Wilson KM, Schuh Am, Mack CL (eds.). Elsevier, Page: 2893-2900, 2025.
Ahluwalia M, Liu J, Olivotto I, Parikh V, Ashley EA, Michels M, Ingles J, Lampert R, Stendahl JC, Colan SD, Abrams D, Pereira AC, Rossano JW, Ryan TD, Owens AT, Ware JS, Saberi S, Helms AS, Day S, Claggett B, Ho CY, Lakdawala NK: Clinical trajectory of NYHA functional class I patients with obstructive hypertrophic cardiomyopathy. JACC Heart Failure. JACC: Heart Failure 13: 332-343, 2025.
Schmitt C, Beasley G, Guerrier K, Kramer J, Naim MY, Griffis H, McNally B, Chan PS, Al-Araji R, Rossano J. : COVID-19 and pediatric out-of-hospital cardiac arrest using U.S. registry database. Resuscitation Plus 22: 100869, 2025.
Ostrominski JW, Claggett BL, Jerosch-Herold M, Raja AA, Day SM, Russell MW, Zahka K, Pereira AC, Colan SD, Murphy AM, Canter C, Bach RG, Wheeler MT, Rossano JW, Owens AT, Mestroni L, Taylor MRG, Patel AR, Wilmot I, Soslow JH, Becker JR, Lakdawala NK, Bundgaard H, Vargas JD, Ho CY; Valsartan for Attenuating Disease Evolution in Early Sarcomeric Hypertrophic Cardiomyopathy (VANISH) Investigators: Valsartan and cardiac remodeling in early-stage hypertrophic cardiomyopathy: the VANISH randomized clinical trial cardiac magnetic resonance substudy. JAMA Cardiology 2025 Notes: In Press.
Greenberg B, Taylor M, Adler E, Colan S, Ricks D, Yarabe P, Battiprolu G, Shah K, Coggins M, Carou-Keenan S, Schwartz JD, Rossano JW: Phase 1 study of AAV9.LAMP2B gene therapy in Danon disease. The New England Journal of Medicine 392: 972-983, 2025.
Wooster L, O’Connor MJ, Zhang X, Mavroudis CD, Maeda K, Ahmed H, Edwards J, Lin KY, Wittlieb-Weber C, Rossano J, Edelson JB: Impact of heart transplant allocation changes on waitlist mortality and clinical practice in pediatric and adult patients with congenital heart disease and cardiomyopathy. Circulation 2025 Notes: In Press