Joseph W. Rossano, MD, MS, MHCM

Professor of Pediatrics (Cardiology) at the Children's Hospital of Philadelphia
Core Faculty, Center for Pediatric Clinical Effectiveness, Children’s Hospital of Philadelphia Research Institute
Core Faculty, Cardiovascular Outcomes, Quality, and Evaluative Research Center, University of Pennsylvania
Senior Fellow, Leonard Davis Institute of Health Care Economics, University of Pennsylvania
Chief, Division of Cardiology, Children's Hospital of Philadelphia
Co-Executive Director, The Cardiac Center, Children's Hospital of Philadelphia
Jennifer Terker Endowed Chair in Pediatric Cardiology, Children's Hospital of Philadelphia
Department: Pediatrics
Contact information
The Children’s Hospital of Philadelphia
Division of Cardiology
34th Street and Civic Center Boulevard
Room 8NW81
Philadelphia, PA 19104
Division of Cardiology
34th Street and Civic Center Boulevard
Room 8NW81
Philadelphia, PA 19104
Office: 267-425-6116
Fax: 215-590-1340
Fax: 215-590-1340
Education:
B.S. (Zoology)
Northern Arizona University, 1996.
M.D. (Doctor of Medicine )
The University of Arizona College of Medicine, 2001.
M.S. (Clinical Research)
Baylor College of Medicine, 2011.
M.H.C.M (Health Care Management)
Harvard T.H. Chan School of Public Health, 2022.
Permanent linkB.S. (Zoology)
Northern Arizona University, 1996.
M.D. (Doctor of Medicine )
The University of Arizona College of Medicine, 2001.
M.S. (Clinical Research)
Baylor College of Medicine, 2011.
M.H.C.M (Health Care Management)
Harvard T.H. Chan School of Public Health, 2022.
Selected Publications
Butters A, Arnott C, Sweeting J, Claggett B, Cuomo A, Abrams D, Ashley EA, Day SM, Helms AS, Lampert R, Lin K, Michels M, Miller EM, Olivotto I, Owens A, Parikh VN, Pereira AC, Rossano JW, Ryan TD, Saberi S, Stendahl JC, Ware JS, Atherton J, Semsarian C, Lakdawala NK, Ho CY, Ingels J: Sex-specific clinical and genetic factors associated with adverse outcomes in hypertrophic cardiomyopathy. Circulation: Genomic and Precision Medicine. In Press, 2025Griffiths ER, Profsky MP, Mokshagundam D, Boucek K, Amdani S, Davies RR, Monge MC, Morales DL, Rossano JW, Jacobs JP, Kirklin JK, Koehl D, Cantor R, Peng DM; Pedimacs Investigators: Eighth annual Society of Thoracic Surgeons Pedimacs report. The Annals of Thoracic Surgery 119: 513-522, 2025.
Chaudhary A, O’Connor M, Edelson J, Rossano J, Lorts A, Rosenthal D, Shezad M, Wright L, Maeda K, VanderPluym C, Ahmed H: Evaluation of gender disparities among pediatric patients with the HeartMate 3 ventricular assist device. The Journal of Heart and Lung Transplantation 44: S580-S581, 2025.
Kozyak BW, Eichner J, Montgomery C, Weiss F, Seigart A, Collier H, Hager A, Weller J, Raffini L, Lambert MP, Anton-Martin P, Shankar VR, Gardner MM, Maeda K, Rossano J, Wittlieb-Weber C, Masood I, Mirreh M, Romeo DA, Tang J, Dewitt A, O’Connor M, Edelson J.: Peri-procedure anti-platelet therapy for patients on paracorporeal ventricular assist devices. The Journal of Heart and Lung Transplantation 44: S360, 2025.
Sutcliffe DL, Lee J, Lu M, Sleeper LA, Albers El, Alejos JC, Almong CS, Ameduri R, Auerbach SR, Barnes A, Bock MJ, Butto A, Carlo WF, Castleberry C, Chrisant M, Deshpande S, Dreyer WJ, Everitt M, Feingold B, Hollander SA, Hsu D, Kindel S, Lal A, Lytrivi ID, Miyamoto S, Peng D, Rossano JW, Ryan TD, Su JA, Thrush P, Ybarra AM, Zangwill S, Daly KP: Trough levels prediction of major adverse events: a report from the TEAMMATE trial. The Journal of Heart and Lung Transplantation 44: S54, 2025.
Montgomery C, Dewitt A, Kozyak B, Ha L, Weiss F, Eichner J, Wittlieb-Weber C, Ahmed H, Maeda K, Tang J, Lane-Fall M, Rosenthal T, Gardner MM, Rossano J, O’Connor M, Edelson J: A programmatic approach to promote and identify ventricular recovery in pediatric patients supported with ventricular assist devices. The Journal of Heart and Lung Transplantation 44: S359, 2025.
Ludomirsky AB, O’Connor M, Dewitt A, Mavroudis C, Gaynor J, Eichner J, Montgomery C, Weiss F, Ha L, Boyle C, Cardoso Cavalcante R, Rossano J, Maeda K, Edelson: Using the Berlin Excor as a total artificial heart can provide durable support to an infant with congenital heart disease. The Journal of Heart and Lung Transplantation 44: S357, 2025.
Ludomirsky AB, Russell W, Lin K, O’Connor M, Wittlieb-Weber C, Ahmed H, Reza N, Bittermann T, Dewitt A, Griffis H, Zhang X, Huang Y, Rossano J, Edelson J: Resource utilization in adolescent and adult cardiomyopathy and heart failure. The Journal of Heart and Lung Transplantation 44: S627, 2025.
Greenberg B, Taylor M, Adler E, Colan S, Ricks D, Yarabe P, Battiprolu G, Shah K, Coggins M, Carou-Keenan S, Schwartz JD, Rossano JW: Phase 1 study of AAV9.LAMP2B gene therapy in Danon disease. The New England Journal of Medicine 392: 972-983, 2025.
Wooster L, O’Connor MJ, Zhang X, Mavroudis CD, Maeda K, Ahmed H, Edwards J, Lin KY, Wittlieb-Weber C, Rossano J, Edelson JB: Impact of heart transplant allocation changes on waitlist mortality and clinical practice in pediatric and adult patients with congenital heart disease and cardiomyopathy. Circulation 151: 814-824, 2025.