Brian R White, MD, PhD
Assistant Professor of Pediatrics (Cardiology)
Attending Physician, Children's Hospital of Philadelphia
Member, Intellectual and Developmental Disabilities Research Center, Children's Hospital of Philadelphia
Department: Pediatrics
Graduate Group Affiliations
Contact information
Children's Hospital of Philadelphia
Abramson Research Center, 907C
3615 Civic Center Blvd.
Philadelphia, PA 19104
Abramson Research Center, 907C
3615 Civic Center Blvd.
Philadelphia, PA 19104
Office: 267-283-7835
Fax: 215-590-5825
Lab: 215-590-3548
Fax: 215-590-5825
Lab: 215-590-3548
Email:
brian.white@post.harvard.edu
brian.white@post.harvard.edu
Publications
Education:
BA (Physics)
Harvard University, 2004.
MD
Washington University School of Medicine in St. Louis, 2012.
PhD (Physics)
Washington University School of Medicine in St. Louis, 2012.
Permanent linkBA (Physics)
Harvard University, 2004.
MD
Washington University School of Medicine in St. Louis, 2012.
PhD (Physics)
Washington University School of Medicine in St. Louis, 2012.
Description of Clinical Expertise
I am a pediatric cardiologist with expertise in both general cardiology outpatient care as well as echocardiography. I treat pediatric patients with both congenital and acquired heart disease.Description of Research Expertise
My laboratory is interested in developing novel optical neuroimaging techniques to better understand pediatric neurodevelopment and its disruption by pediatric diseases (congenital heart disease, prematurity, stroke). Namely, we use widefield optical imaging (WOI) in mice and diffuse optical tomography (DOT) in large animals and humans to probe brain function. Our analysis methods focus on resting-state methods (e.g., functional connectivity) as a way to probe brain integrity at the bedside. We are also interesting in algorithm development, including new statistical methods to ensure rigor and reproducibility. We collaborate with many researchers at CHOP and Penn including biostatisticians, optical imagers, and labs that develop animal models of disease.Selected Publications
Y Hao, SN Vandekar, BR White, RT Shinohara: Interaction Between Subject and Group Effects in the SPICE Test for Intermodal Correspondence. Organization for Human Brain Mapping Annual Meeting Jun 2026 Notes: Bordeaux, France.J Zhang, A Palmucci, H Fisher, RM Forti, BR White: Subject-Specific Monte Carlo Modeling of Photon Transport for Optical Neuroimaging in Mice. Organization for Human Brain Mapping Annual Meeting Jun 2026 Notes: Bordeaux, France.
Y Hao, O Harel, SN Vandekar, RT Shinohara, BR White: Imputing Missing Neuroimaging Data while Maintaining Spatial Autocorrelation. Organization for Human Brain Mapping Annual Meeting Jun 2026 Notes: Bordeaux, France.
J Zhang, A Palmucci, H Fisher, RM Forti, BR White: Subject-Specific Monte Carlo Modeling for Optical Neuromonitoring and Neuroimaging in Mice. Optica Biophotonics Congress Apr 2026 Notes: Ft. Lauderdal, FL.
AT Subhash, D Derman, HB FIsher, SA Paladugu, TS Ko, BR White, SL Ferradal: Developing Diffuse Optical Tomography for Peri-Arrest Monitoring in Piglet. Optica Biophotonics Congress Apr 2026 Notes: Ft. Lauderdale, FL.
A Asadian, D Derman, BR White, SL Ferradal: Independent Component Analysis Denoising Improves Reliability of Widefield Optical Imaging Functional Connectivity. Optica Biophonotics Congress Apr 2026 Notes: Ft. Lauderdale, FL.
A Palmucci, H Mestre-Payne, H Fisher, E Goldberg, BR White: Neurovascular Effects of Seizure and Cortical Spreading Depolarization Imaged with Widefield Optical Imaging. Optica Biophotonics Congress Apr 2026 Notes: Ft. Lauderdale, FL.
Y Hao, O Harel, SN Vandekar, RT Shinohara, BR White: Maintaining Spatial Autocorrelation During Imputation of Missing Neuroimaging Data. Optica Biophotonics Congress Apr 2026 Notes: Ft. Lauderdale, FL.
Y Hao, O Harel, SN Vandekar, RT Shinohara, BR White: Maintaining Spatial Autocorrelation in Neuroimaging with Multiple Imputation. ENAR Spring Meeting Mar 2026 Notes: Indianapolis, IN.
AT Subhash, A Crozier, HB Fisher, AS Paladugu, D Derman, SL Ferradal, TS Ko, BR White: Developing Diffuse Optical Tomography for Longitudinal Neuroimaging in a Piglet Model of Pediatrics Cardiac Arrest. Cardiology 2026: 29th Annual Update on Pediatric and Congenital Cardiovascular Disease Feb 2026 Notes: Scottsdale, AZ.
