Brian R White, MD, PhD

faculty photo
Assistant Professor of Pediatrics
Department: Pediatrics
Graduate Group Affiliations

Contact information
Children's Hospital of Philadelphia
Abramson Research Center, 907C
3615 Civic Center Blvd.
Philadelphia, PA 19104
Office: 267-283-7835
Fax: 215-590-5825
Lab: 215-590-3548
BA (Physics)
Harvard University, 2004.
PhD (Physics)
Washington University School of Medicine in St. Louis, 2012.
Washington University School of Medicine in St. Louis, 2012.
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Description of Clinical Expertise

I am a pediatric cardiologist with expertise in both general cardiology outpatient care as well as echocardiography. I treat pediatric patients with both congenital and acquired heart disease.

Description of Research Expertise

My laboratory is interested in developing novel optical neuroimaging techniques to better understand pediatric neurodevelopment and its disruption by pediatric diseases (congenital heart disease, prematurity, stroke). Namely, we use optical intrinsic signal (OIS) imaging and diffuse optical tomography (DOT) along with resting-state methods such as functional connectivity. This combination of methods allows true bench-to-bedside neuroimaging. Specifically, my laboratory is interested in analytical technique development, animal models of pediatric disease, and translational studies in humans.

Selected Publications

B.R. White, C. Chan, T. Adepoju, S. Da Silva, E.K. Shih: Evolution of ischemic stroke assessed with resting-state hemodynamics in mice. SPIE Photonics West 2023.

B.R. White, C. Chan, T. Adepoju, R.T. Shinohara, and S. Vandekar: Controlling the familywise error rate in widefield optical neuroimaging of functional connectivity in mice. Neurophotonics 10: 015004, 2023.

R.M. Forti, T.S. Ko, M.K. Weeks, N.J. Widmann, S.S. Shin, S.H. Kao, B.R. White, A.G. Yodh, T.J. Kilbaugh, W.B. Baker: Non-invasive Assessment of Cerebral Edema, Cerebral Hemorrhage and Cerebral Metabolic Impairments after Traumatic Brain Injury with an Optical Spectroscopy System. Military Health Research Symposium 2023.

R.M. Forti, L.J. Hobson, E. Benson, T.S. Ko, N.R. Ranieri, G. Laurent, M.K. Weeks, N.J. Widman, S. Morton, A.M. Davis, T. Sueishi, Y. Lin, K. Wulwick, N. Fagan, S.S. Shin, S.H. Kao, D.J. Licht, B.R. White, T.J. Kilbaugh, A.G. Yodh, W.B. Baker: Non-invasive diffuse optical monitoring of cerebral physiology in an adult swine model of contusional traumatic brain injury. Biomedical Optics Express 14: 2432-2448, 2023.

B.R. White, K.J. Chaszczewski, B. Lemley, S.S. Natarajan, L.S. Rogers: Sustained improvement in fellows’ echocardiographic completeness through the coronavirus pandemic with a standardized imaging protocol. Cardiology in the Young 33: 69-75, 2023.

T.S. Ko, R.W. Morgan, J.C. Slovis, K. Senthil, D. Aronowitz, R.M. Forti, N. Ranieri, G. Laurent, B. Yun, S. Morton, Y. Lin, K. Weeks, N. Widmann, B.R. White, J.M. Lynch, C.D. Mavroudis, A.G. Yodh, D.J. Licht, T.J. Kilbaugh, W.B. Baker: A Pilot Study of Non-Invasive Optical Neuromonitoring Guidance of Cardiopulmonary Resuscitation. European Conferences on Biomedical Optics 2023.

H. Stanley, B.R. White, C. LaRosa, J.W. Gaynor, A. Strong: Patent ductus arteriosus and coarctation of the aorta in siblings with a novel PRDM6 variant. Cardiology 2023: 26th Annual Update on Pediatric and Congenital Cardiovascular Disease 2023.

W. Baker, R. Forti, P. Heye, K. Heye, Y. Lin, K. Andersen, J. Jahnavi, J. Breimann, H. Gaudio, S. Morton, A. Yodh, D. Licht, B. White, M. Hwang, T. Kilbaugh, T. Ko: A Two-layer Modified Beer-Lambert Algorithm for Optical Monitoring of Critical Closing Pressure. Optica Biophotonics Congress 2023.

RM Forti, LJ Hobson, TS Ko, E Benson, NR Ranieri, G Laurent, M Bowe, MK Weeks, NJ Widmann, S Shin, S Morton, AM Davis, T Sueshi, Y Lin, N Fagan, BR White, DJ Licht, TJ Kilbaugh, AG Yodh, WB Baker: Non-invasive diffuse optical monitoring of cerebral oxygen metabolism, cerebral blood volume and cerebral water content in a swine-model of contusional traumatic brain injury. SPIE Photonics West 2023.

W.B. Baker, R. Forti, P. Heye, K. Heye, N.R. Ranieri, E. Benson, Y. Lin, K.N. Andersen, J. Jahnavi, J. Breimann, H. Gaudio, J.M. Lynch, A.G. Yodh, D.J. Licht, B.R. White, M. Hwang, T.J. Kilbaugh, T.S. Ko: Diffuse optical metrics of intracranial hypertension in a pig model of hydrocephalus. European Conferences on Biomedical Optics 2023.

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Last updated: 09/11/2023
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