Brian R White, MD, PhD
Assistant Professor of Pediatrics (Cardiovascular Medicine)
Department: Pediatrics
Graduate Group Affiliations
Contact information
Children's Hospital of Philadelphia
Abramson Research Center, 907C
3615 Civic Center Blvd.
Philadelphia, PA 19104
Abramson Research Center, 907C
3615 Civic Center Blvd.
Philadelphia, PA 19104
Office: 267-283-7835
Fax: 215-590-5825
Lab: 215-590-3548
Fax: 215-590-5825
Lab: 215-590-3548
Email:
brian.white@post.harvard.edu
brian.white@post.harvard.edu
Publications
Education:
BA (Physics)
Harvard University, 2004.
PhD (Physics)
Washington University School of Medicine in St. Louis, 2012.
MD
Washington University School of Medicine in St. Louis, 2012.
Permanent linkBA (Physics)
Harvard University, 2004.
PhD (Physics)
Washington University School of Medicine in St. Louis, 2012.
MD
Washington University School of Medicine in St. Louis, 2012.
Description of Clinical Expertise
I am a pediatric cardiologist with expertise in both general cardiology outpatient care as well as echocardiography. I treat pediatric patients with both congenital and acquired heart disease.Description of Research Expertise
My laboratory is interested in developing novel optical neuroimaging techniques to better understand pediatric neurodevelopment and its disruption by pediatric diseases (congenital heart disease, prematurity, stroke). Namely, we use optical intrinsic signal (OIS) imaging and diffuse optical tomography (DOT) along with resting-state methods such as functional connectivity. This combination of methods allows true bench-to-bedside neuroimaging. Specifically, my laboratory is interested in analytical technique development, animal models of pediatric disease, and translational studies in humans.Selected Publications
A Asadian, D Derman, T Adepoju, BR White, SL Ferradal: Anesthetic effects on functional connectivity fingerprinting in mice. SPIE Photonics West Jan 2025.WB Baker, RM Forti, N Ranieri, A Hurlock, R Goto, D Anderson, JM Lynch, SS Lang, T Flanders, G Heuer, TS Ko, BR White: Low Frequency Power in Cerebral Blood Flow Detects Impaired Oxygen Metabolism in Neonatal Hydrocephalus. SPIE Photonics West Jan 2025.
H Zhao, B Scammon, J Wu, TS Ko, BR White, RM Forti, JM Kainerstorfer, WB Baker: Estimating intracranial pressure with optically-measured cerebral blood flow cardiac waveforms in pigs. SPIE Photonics West Jan 2025.
RM Forti, LJ Hobson, SL Morton, A Hurlock, R Goto, D Andersona MK Weeks, K Senthil, BR White, TS Ko, KD Browne, DK Cullen, AG Yodh, TJ Kilbaugh, WB Baker: Non-invasive diffuse optical monitoring of cerebral physiology after severe closed-head diffuse injury in swine. SPIE Photonics West Jan 2025.
Hayden B. Fisher, Aurora Yuan, and Brian R. White: A Multi-Atlas Machine Learning Approach for Automated Segmentation of Widefield Optical Imaging in Mice. fNIRS 2024 Sept 2024.
Benjamin N. Zelnick, Ananya Paladugu, Hayden B. Fisher, and Brian R. White: Illumind: An Accessible, Flexible Graphical User Interface for Hemodynamic and Fluorescent Widefield Imaging. fNIRS 2024 Sept 2024.
Hayden B. Fisher, Aurora Yuan, and Brian R. White: A Multi-Atlas Machine Learning Approach for Automated Segmentation of Widefield Optical Imaging in Mice. The Third Britton Chance International Symposium on Metabolic Imaging and Spectroscopy July 2024.
Arjun Yodh, Emilie Benson, Danielle Aronowitz, Rodrigo Forti, Alec Lafontant, Nicolina Ranieri, Jonathan Starr, Richard Melchior, Alistair Lewis, Jharna Jahnavi, Jake Breimann, Bohyun Yun, Gerard Laurent, Jennifer Lynch, Brian White, J. Gaynor, Daniel Licht, Todd Kilbaugh, Constantine Mavroudis, Wesley Baker, Tiffany Ko,: Hematocrit Correction for Diffuse Optical Monitoring of Cerebral Blood Flow and Oxygen Metabolism during Cardiopulmonary Bypass. Optica Biophotonics Congress Apr 2024.
Temilola Adepoju, Hayden Fisher, Chloe Winston, Brian White: Intact-Skull Cranial Windows for Widefield Imaging in Juvenile Mice: Complications and Impact on Skull Growth. Optica Biophotonics Congress Apr 2024.
Sarah Lavery, Temilola Adepoju, Hayden Fisher, Claudia Chan, Aurora Yuan, Amanda Kuhs, Rebecca Ahrens-Nicklas, Brian White: Functional Connectivity Changes in Mouse Models of Maple Syrup Urine Disease. Optica Biophotonics Congress Apr 2024.