Ali Nabavizadeh, MD
Associate Professor of Radiology at the Hospital of the University of Pennsylvania
Active Radiologist, Penn Presbyterian Medical Center
Active Radiologist , Chester County Hospital
Active Radiologist , Pennsylvania Hospital
Attending Radiologist, Hospital of the University of Pennsylvania
Department: Radiology
Contact information
Hospital of the University of Pennsylvania
Department of Radiology
3400 Spruce Street
Philadelphia, PA 19104
Department of Radiology
3400 Spruce Street
Philadelphia, PA 19104
Publications
Education:
MD (School of Medicine)
Shiraz Medical School, 2002.
Permanent linkMD (School of Medicine)
Shiraz Medical School, 2002.
Description of Clinical Expertise
Dr. Nabavizadeh is primarily an adult neuroradiologist with additional training in pediatric neuroradiology and nuclear radiology. He specializes in using neuroimaging to diagnose various diseases of the central nervous system.Description of Research Expertise
Dr. Nabavizadeh is an Associate Professor of Radiology at the Hospital of the University of Pennsylvania with a research appointment at the Children’s Hospital of Philadelphia and the imaging lead of two consortia, CBTN (The Children’s Brain Tumor Network) and PNOC (The Pacific Pediatric Neuro-oncology Consortium) respectively dedicated to biospecimen-driven data generation and precision medicine clinical trials. Dr. Nabavizadeh’s research focuses on multimodality imaging using structural and physiologic MRI imaging with additional PET probes and molecular imaging techniques to better understand the complex nature of brain tumor microenvironment. Dr. Nabavizadeh is the associate editor for the brain tumor section at the American Journal of Neuroradiology and has more than 140 peer-reviewed publications in prestigious journals such as Nature Medicine, Nature Communications, JAMA Neurology, Clinical Cancer Research, Neuro-Oncology, Radiology, and Journal of Nuclear Medicine. He has served as the principal investigator of multiple prospective imaging trials including investigator-initiated trials and industry-sponsored FDA registry trials.Selected Publications
Bagley SJ, Desai AS, Fraietta JA, Silverbush D, Chafamo D, Freeburg NF, Gopikrishna GK, Rech AJ, Nabavizadeh A, Bagley LJ, Park J, Jarocha D, Martins R, Sarmiento N, Maloney E, Lledo L, Stein C, Marshall A, Leskowitz RM, Jadlowsky JK, Mackey S, Christensen S, Oner BS, Plesa G, Brennan A, Gonzalez V, Chen F, Barrett D, Colbourn R, Nasrallah MP, Mourelatos Z, Hwang WT, Alanio C, Siegel DL, June CH, Hexner EO, Binder ZA, O'Rourke DM.: Intracerebroventricular bivalent CAR T cells targeting EGFR epitope 806 and IL-13Rα2 in recurrent glioblastoma: a phase 1 dose finding study. Nature Medicine June 2025.Kraya A, Rathi K, Jin R, Kesherwani V, Resnick AC, Storm PB, Nabavizadeh A.: Evaluating the Potential of PSMA Targeting in CNS Tumors: Insights from Large-Scale Transcriptome Profiling. Cancers 6(17 (7)), Apr 2025.
Divyanshu Tak , Biniam A. Garomsa , Anna Zapaishchykova , Zezhong Ye , Sridhar Vajapeyam , Maryam Mahootiha , Juan Carlos Climent Pardo ,Ceilidh Smith , Ariana M. Familiar , Tafadzwa Chaunzwa , Kevin X. Liu , Sanjay Prabhu , Pratiti Bandopadhayay , Ali Nabavizadeh , Sabine Mueller , Hugo J. W. L. Aerts , Daphne Haas-Kogan , Tina Y. Poussaint , Benjamin H. Kann.: Longitudinal Risk Prediction for Pediatric Glioma with Temporal Deep Learning. NEJM AI 2(5), Apr 2025.
Kazerooni AF, Kraya A, Rathi KS, Kim MC, Kesherwani V, Corbett R, Vossough A, Khalili N, Gandhi D, Familiar NKAM, Jin R, Huang X, Zhu Y, Sickler A, Lueder MR, Phul S, Storm PB, Ware JB, Foster JB, Mueller S, Rokita JL, Fisher MJ, Resnick AC, Nabavizadeh A.: Imaging Clusters of Pediatric Low-Grade Glioma are Associated with Distinct Molecular Characteristics. AJNR Am J Neuroradiol Feb 2025.
Kazerooni AF, Kraya A, Rathi KS, Kim MC, Kesherwani V, Corbett R, Vossough A, Khalili N, Gandhi D, Familiar NKAM, Jin R, Huang X, Zhu Y, Sickler A, Lueder MR, Phul S, Storm PB, Ware JB, Foster JB, Mueller S, Rokita JL, Fisher MJ, Resnick AC, Nabavizadeh A.: Imaging Clusters of Pediatric Low-Grade Glioma are Associated with Distinct Molecular Characteristics. AJNR Am J Neuroradiol Feb 2025.
Wills CA, Mohan S, Nabavizadeh A, Patel T, Prior T, Mansour M, McCoy E, Shah S, Angeloni N, O'Neill M, Frangos S, Blessing C, Coghlan L, Maloney E, Wileyto EP, Desai AS, Bagley SJ.: A single-arm phase 2 study of abemaciclib in adult patients with recurrent grade 3 oligodendroglioma. Neurooncol Adv . Jan 2025.
Fathi Kazerooni A, Kraya A, Rathi KS, Kim MC, Vossough A, Khalili N, Familiar AM, Gandhi D, Khalili N, Kesherwani V, Haldar D, Anderson H, Jin R, Mahtabfar A, Bagheri S, Guo Y, Li Q, Huang X, Zhu Y, Sickler A, Lueder MR, Phul S, Koptyra M, Storm PB, Ware JB, Song Y, Davatzikos C, Foster JB, Mueller S, Fisher MJ, Resnick AC, Nabavizadeh A.: Multiparametric MRI Along with Machine Learning Informs on Molecular Underpinnings, Prognosis, and Treatment Response In Pediatric Low-Grade Glioma. Nature Communications Jan 2025.
Mahootiha M, Tak D, Ye Z, Zapaishchykova A, Likitlersuang J, Climent Pardo JC, Boyd A, Vajapeyam S, Chopra R, Prabhu SP, Liu KX, Elhalawani H, Nabavizadeh A, Familiar A, Mueller S, Aerts HJWL, Bandopadhayay P, Ligon KL, Haas-Kogan D, Poussaint TY, Qadir HA, Balasingham I, Kann BH.: Multimodal Deep Learning Improves Recurrence Risk Prediction in Pediatric Low-Grade Gliomas. Neuro Oncol Jan 2025.
Till JE, Seewald NJ, Yazdani Z, Wang Z, Ballinger D, Samberg H, Dandu S, Macia C, Yin M, Abdalla A, Prior T, Shah S, Patel T, McCoy E, Mansour M, Wills CA, Bochenek V, Serrano J, Snuderl M, Phillips RE, O'Rourke DM, Amankulor NM, Nabavizadeh A, Desai AS, Gollomp K, Binder ZA, Zhou W, Bagley SJ, Carpenter EL.: Corticosteroid-dependent association between prognostic peripheral blood cell-free DNA levels and neutrophil-mediated NETosis in patients with glioblastoma. Clin Cancer Res Jan 2025.
Familiar AM, Khalili N, Khalili N, Schuman C, Grove E, Viswanathan K, Seidlitz J, Alexander-Bloch A, Zapaishchykova A, Kann BH, Vossough A, Storm PB, Resnick AC, Kazerooni AF, Nabavizadeh A.: An automated face de-identification AI tool to empower data sharing of pediatric brain MRIs. AJNR Am J Neuroradiol. Nov 2024.