Selected Publications

Evan Gallagher, Shihong Li,Hsiaoju Lee, Hong Xu, Virginia M.-Y. Lee,Robert H. Mach, and Meagan J. McManus: Noninvasive Detection of Oxidative Stress in a Mouse Model of 4R Tauopathy via Positron Emission Tomography with [18F]ROStrace. Int. J. Mol. Sci. 26(5): 1845, Feb 2025.

Hoon Choi, Mamta Gupta, Arjun Sengupta, Emma E. Furth, Christopher Hensley, Aalim M. Weljie, Hsiaoju Lee, Yu-Ting Lu, Austin Pantel, David Mankoff, Rong Zhou: Disruption of redox balance in glutaminolytic triple negative breast cancer by inhibition of glutaminase and glutamate export. Neoplasia 61, 2025 Notes: https://doi.org/10.1016/j.neo.2025.101136.

Gallagher, E., Hou, C., Zhu, Y., Hsieh, C. J., Lee, H., Li, S., Xu, K., Henderson, P., Chroneos, R., Sheldon, M., Riley, S., Luk, K. C., Mach, R. H., McManus, M. J.: Positron Emission Tomography with [(18)F]ROStrace Reveals Progressive Elevations in Oxidative Stress in a Mouse Model of Alpha-Synucleinopathy. Int J Mol Sci 25(9), 2024.

Hsieh CJ, Hou C, Lee H, Tomita C, Schmitz A, Plakas K, Dubroff JG, Mach RH.: Total-body imaging of mu-opioid receptors with [(11)C]carfentanil in non-human primates. Eur J Nucl Med Mol Imaging 2024.

Zhu, Y., Kohli, N., Young, A., Sheldon, M., Coni, J., Rajasekaran, M., Robinson, L., Chroneos, R., Riley, S., Guarnieri, J. W., Jose, J., Patel, N., Wallace, D. C., Li, S., Lee, H., Mach, R. H., McManus, M. J.: PET Imaging with [(18)F]ROStrace Detects Oxidative Stress and Predicts Parkinson''s Disease Progression in Mice. Antioxidants (Basel) 13(10), 2024.

Young, A. J., Pantel, A. R., Kiani, M., Doot, R. K., Bagheri, S., Pryma, D. A., Farwell, M. D., Li, S., Lee, H., Schubert, E. K., Secreto, A., Zuckerman, S. P., Nayak, A., Choi, H., Carlin, S., DeMichele, A., Mankoff, D. A., Zhou, R., Mach, R. H., McDonald, E. S.: Kinetic Analysis and Metabolism of Poly(Adenosine Diphosphate-Ribose) Polymerase-1-Targeted (18)F-Fluorthanatrace PET in Breast Cancer. J Nucl Med 2024.

Li, S., Schmitz, A., Lu, Y. T., Pal, R., Sarkar, S., Sellmyer, M. A., Mach, R. H., Lee, H.: Automation of simplified two-step radiolabeling via ditosylate synthon for (18)F-labeled radiotracers using AllinOne module. Nucl Med Biol 138-139: 108948, 2024.

Ho Young Kim 1, Wai Kit Chia 1, Chia-Ju Hsieh 1, Dinahlee Saturnino Guarino 1, Thomas J A Graham 1, Zsofia Lengyel-Zhand 1, Mark Schneider 1, Cosette Tomita 1, Marshall G Lougee 2, Hee Jong Kim 3, Vinayak V Pagar 2, Hsiaoju Lee 1, Catherine Hou 1, Benjamin A Garcia 3, E James Petersson 2, Jennifer O'Shea 4, Paul T Kotzbauer 4, Chester A Mathis 5, Virginia M-Y Lee 6, Kelvin C Luk 6, Robert H Mach 1: A Novel Brain PET Radiotracer for Imaging Alpha Synuclein Fibrils in Multiple System Atrophy. J. Med. Chem. 66(17): 12185-12201, Sep 2023.

Reagan R Wetherill, Robert K Doot, Anthony J Young, Hsiaoju Lee, Erin K Schubert, Corinde E Wiers, Frank T Leone, Robert H Mach, Henry R Kranzler, Jacob G Dubroff: Molecular Imaging of Pulmonary Inflammation in Users of Electronic and Combustible Cigarettes: A Pilot Study. J Nucl Med 64(5): 797-802, May 2023.

Rong Zhou 1, Hoon Choi 2, Jianbo Cao 2, Austin Pantel 2, Mamta Gupta 2, Hsiaoju S Lee 2, David Mankoff 1: 18F-Fluciclovine PET Imaging of Glutaminase Inhibition in Breast Cancer Models. J Nucl Med 64(1): 131-136, Jan 2023.