Jeffrey Scott Phillips, PhD
Research Assistant Professor of Neurology
Department: Neurology
Graduate Group Affiliations
Contact information
B602 Richards
Penn Frontotemporal Degeneration Center
3700 Hamilton Walk
Philadelphia, PA 19104
Penn Frontotemporal Degeneration Center
3700 Hamilton Walk
Philadelphia, PA 19104
Publications
Links
Search PubMed for articles
Penn Frontotemporal Degeneration Center profile
Github site for academic research projects
Search PubMed for articles
Penn Frontotemporal Degeneration Center profile
Github site for academic research projects
Education:
BA (English & Honors)
Villanova University, 1997.
MS (Cognitive psychology)
University of Pittsburgh, 2009.
PhD (Cognitive psychology)
University of Pittsburgh, 2012.
Permanent linkBA (English & Honors)
Villanova University, 1997.
MS (Cognitive psychology)
University of Pittsburgh, 2009.
PhD (Cognitive psychology)
University of Pittsburgh, 2012.
Description of Research Expertise
Atypical Alzheimer's diseaseFrontotemporal dementia
Magnetic resonance imaging (MRI)
Positron emission tomography (PET): amyloid and tau
Computational neuroimaging
Statistical programming (R, Python)
Selected Publications
Briar Nowling, Hamsanandini Radhakrishnan, Christopher A. Sandolm, Christopher Brown, Sandhitsu Das, James C. Gee, Corey T. McMillan, Allison Snyder, Lauren Massimo, David A. Wolk, David J. Irwin, and Jeffrey S. Phillips: Developing a novel metric of atypicality in Alzheimer's disease regional volume changes. AD/PD 2026 International Conference on Alzheimer's and Parkinson's Diseases, Copenhagen. 2026.McKinstry, D., Shi, Z., Ramos-Rolón, A. P., Phillips, J., Das, S., Li, X., Hager, N. M., Pond, T., Volkow, N. D., Kranzler, H. R., Dubroff, J. G., Nasrallah, I. M., & Wiers, C. E.: Hippocampal volume and brain tau pathology in opioid use disorder: Associations with non-fatal opioid overdose. Addiction Neuroscience 19: 100253, 2026.
Khandelwal, P., Duong, M. T., Levorse, L. M., A. Lim, S., Gauthier, N., Shenoy, V., Chung, E., Denning, A. E., Bahena, A., Trotman, W., Olm, C. A., Radhakrishnan, H., Ittyerah, R., Prabhakaran, K., Mizsei, G., Schuck, T., Robinson, J., Ohm, D. T., Phillips, J. S., ... Yushkevich, P. A.: VIOLET: Volumetric Image registration via Optimization and Learning for Efficient image Translation. Simulation and Synthesis in Medical Imaging V. Fernandez, D. Wiesner, L. Zuo, A. Casamitjana, & S. W. Remedios (eds.). Springer Nature Switzerland, Page: 84-96, 2026.
John L Robinson, Helen Cai, Nicholas J Loh, Omar Vazquez, Zahra Khodakaramimaghsoud, EunRan Suh, Vivianna M. Van Deerlin, Paul A. Yushkevich, Sharon X. Xie, Daniel T Ohm, David J Irwin, Jeffrey S Phillips, Edward B Lee.: Idiotypic-susceptible: a clinically relevant, neurofibrillary tangle subtype of Alzheimer's disease. Acta Neuropathologica 2026.
Daniel T. Ohm, Noah Capp, Philip Sabitini, Katheryn A.Q. Cousins, Jeffrey S. Phillips, Katya Rascovsky, David A. Wolk, Edward B. Lee, Corey T. McMillan, and David J. Irwin: Selectively vulnerable myeloarchitecture in behavioral variant frontotemporal dementia. Society for Neuroscience Annual Meeting 2025.
Watanabe, R., Papatriantafyllou, J. D., Maeda, K., Aguirre, G. K., Ando, M., Benoit, B., Grossman, M., Irwin, D. J., Kim, B., Massimo, L., McMillan, C. T., Papageorgiou, S. G., Phillips, J. S., Shiraishi, T., Sugihara, Y., Suh, E., Takashima, H., Toro, C., Van Deerlin, V. M., Nasrallah, I. M., and Lee, E. B.: Clinicopathological characterization of vacuolar tauopathy associated with VCP D395G. Alzheimer’s & Dementia 21(7): e70427, 2025.
Jesse S Cohen, Jeffrey Phillips, Sandhitsu R Das, Christopher A Olm, Hamsanandini Radhakrishnan, Emma Rhodes, Katheryn AQ Cousins, Sharon X Xie, Ilya M Nasrallah, Paul A Yushkevich, David A Wolk, Edward B Lee, Daniel Weintraub, David J Irwin, and Corey T McMillan: Posterior hippocampal sparing in Lewy body disorders with Alzheimer’s copathology: An in vivo MRI study. NeuroImage: Clinical 45(103714), 2025.
Jeffrey S. Phillips, Dahlia Kamel, Sevila Temirova, Marianthi Hareras, Chigozie Ibe, Quinn Hlava, Emily Xie, Katheryn A. Q. Cousins, Leslie M. Shaw, Sandhitsu R. Das, Jeffrey Maneval, Sara Manning, Christopher Brown, Katherine Lopez, Richard Keegan, Andrew Stephens, Corey T. McMillan, David J. Irwin, Liz Li, Ilya M. Nasrallah, and David A. Wolk: [18F]-PI-2620 uptake in the medial temporal lobes discriminates Alzheimer's disease from normal cognition and non-Alzheimer's dementias. Human Amyloid Imaging 2025.
Matyi, M. A., Radhakrishnan, H., Olm, C. A., Phillips, J. S., Cook, P. A., Rhodes, E., Gee, J. C., Irwin, D. J., McMillan, C. T., & Massimo, L.: Executive dysfunction relates to salience network desegregation in behavioral variant frontotemporal dementia. NeuroImage: Clinical 48: 103853, 2025.
Khandelwal, P., Duong, M. T., Levorse, L. M., Trotman, W., Bahena, A., Lim, S. A., Denning, A. E., Chung, E., Olm, C. A., Radhakrishnan, H., Ittyerah, R., Prabhakaran, K., Mizsei, G., Schuck, T., Emrani, S., Vizcarra, J. A., Robinson, J., Ohm, D. T., Phillips, J. S., … Yushkevich, P. A.: Postmortem brain MRI reveals differential associations of subcortical and limbic volumes with cortical thinning and neuropathology patterns. bioRxiv Page: 2025.12.30.697140, 2025.