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Jeffrey Scott Phillips, PhD
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Research Assistant Professor of Neurology
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Department: Neurology
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Graduate Group Affiliations
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- Neuroscience e
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Contact information
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B602 Richards
2f Penn Frontotemporal Degeneration Center
35 3700 Hamilton Walk
Philadelphia, PA 19104
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2f Penn Frontotemporal Degeneration Center
35 3700 Hamilton Walk
Philadelphia, PA 19104
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Publications
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Links
b5 Search PubMed for articles
95 Penn Frontotemporal Degeneration Center profile
78 Github site for academic research projects
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b5 Search PubMed for articles
95 Penn Frontotemporal Degeneration Center profile
78 Github site for academic research projects
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Education:
21 7 BA 1d (English & Honors) c
2d Villanova University, 1997.
21 7 MS 21 (Cognitive psychology) c
31 University of Pittsburgh, 2009.
21 8 PhD 21 (Cognitive psychology) c
31 University of Pittsburgh, 2012.
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Permanent link21 7 BA 1d (English & Honors) c
2d Villanova University, 1997.
21 7 MS 21 (Cognitive psychology) c
31 University of Pittsburgh, 2009.
21 8 PhD 21 (Cognitive psychology) c
31 University of Pittsburgh, 2012.
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1f Frontotemporal dementia
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28 Magnetic resonance imaging (MRI)
3b Positron emission tomography (PET): amyloid and tau
22 Computational neuroimaging
2a Statistical programming (R, Python)
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Description of Research Expertise
2d Atypical Alzheimer's disease1f Frontotemporal dementia
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28 Magnetic resonance imaging (MRI)
3b Positron emission tomography (PET): amyloid and tau
22 Computational neuroimaging
2a Statistical programming (R, Python)
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187 Shen, T., Vogel, J. W., Van Deerlin, V. M., Suh, E., Dratch, L., Phillips, J. S., Massimo, L., Lee, E. B., Irwin, D. J., & McMillan, C. T.: Disparate and shared transcriptomic signatures associated with cortical atrophy in genetic behavioral variant frontotemporal degeneration. Molecular Degeneration 20(1): 17, 2025.
18c Kim, B. J., Aleman, T. S., Cousins, K. A. Q., Daniel, E., Smith, E., Iacobucci, E., Kolomeyer, A., Hwang, C. K., McMillan, C. T., Van Deerlin, V. M., Phillips, J. S., Yu, Y., Ying, G.-S., & Irwin, D. J.: Choroidal evaluation of FTLD-Tau and biomarker-determined Alzheimer’s disease. Scientific Reports 15(1): 22290, 2025.
204 Watanabe, R., Papatriantafyllou, J. D., Maeda, K., Aguirre, G. K., Ando, M., Benoit, B., Grossman, M., Irwin, D. J., Kim, B., Massimo, L., McMillan, C. T., Papageorgiou, S. G., Phillips, J. S., Shiraishi, T., Sugihara, Y., Suh, E., Takashima, H., Toro, C., Van Deerlin, V. M., Nasrallah, I. M., and Lee, E. B.: Clinicopathological characterization of vacuolar tauopathy associated with VCP D395G. Alzheimer’s & Dementia 21(7): e70427, 2025.
1e3 Jesse S Cohen, Jeffrey Phillips, Sandhitsu R Das, Christopher A Olm, Hamsanandini Radhakrishnan, Emma Rhodes, Katheryn AQ Cousins, Sharon X Xie, Ilya M Nasrallah, Paul A Yushkevich, David A Wolk, Edward B Lee, Daniel Weintraub, David J Irwin, and Corey T McMillan: Posterior hippocampal sparing in Lewy body disorders with Alzheimer’s copathology: An in vivo MRI study. NeuroImage: Clinical 45(103714), 2025.
2b9 Katheryn Alexandra Quilico Cousins, David J Irwin, Thomas F Tropea, Emma Rhodes, Jeffrey S Phillips, Alice Chen-Plotkin, Michael C Brumm, Christopher S Coffey, Ju Hee Kang, Tanya Simuni, Tatiana Foroud, Arthur W Toga, Caroline M Tanner, Karl Kieburtz, Brit M Mollenhauer, Douglas R Galasko, Samantha Hutten, Daniel Weintraub, Andrew Siderowf, Kenneth Marek, Kathleen L Poston, Leslie M Shaw, Parkinson's Progression Marker Initiative: Evaluation of ATN-PD framework and biofluid markers to predict cognitive decline in early Parkinson's disease. Neurology 102(4): e208033, Feb 2024 Notes: doi: 10.1212/WNL.0000000000208033.
17c Jeffrey S. Phillips, John L. Robinson, Katheryn A. Q. Cousins, David A. Wolk, Edward B. Lee, Corey T. McMillan, John Q. Trojanowski, Murray Grossman, and David J. Irwin: Polypathologic associations with grey matter atrophy in neurodegenerative disease. Journal of Neuroscience 44(6): e0808232023, Feb 2024
178 Rhodes E, Mechanic-Hamilton D, Phillips JS, Bahena A, Vitali N, Hlava Q, Cook P, Gee J, Grossman M, McMillan C, Massimo L: Discrepancies in patient and caregiver ratings of personality change in Alzheimer’s disease and related dementias. Archives of Clinical Neuropsychology 39(4): 399-408, May 2024.
1aa Cousins, K.A., Phillips, J.S., Das, S.R., O'Brien, K., Tropea, T.F., Chen‐Plotkin, A., Shaw, L.M., Nasrallah, I.M., Mechanic‐Hamilton, D., McMillan, C.T. and Irwin, D.J.: Pathologic and cognitive correlates of plasma biomarkers in neurodegenerative disease. Alzheimer's & Dementia 20(6): 3889-3905, Apr 2024 Notes: https://doi.org/10.1002/alz.13777.
1b5 Arezoumandan S, Cousins KAQ, Ohm DT, Lowe M, Chen M, Gee J, Phillips JS, McMillan CT, Luk KC, Deik A, Spindler MA, Tropea TF, Weintraub D, Wolk DA, Grossman M, Lee V, Chen-Plotkin AS, Lee EB, Irwin DJ.: Tau maturation in the clinicopathological spectrum of Lewy body and Alzheimer's disease. Annals of Clinical and Translational Neurology 11(3): 673-685, Mar 2024.
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Selected Publications
249 Jeffrey S. Phillips, Dahlia Kamel, Sevila Temirova, Marianthi Hareras, Chigozie Ibe, Quinn Hlava, Emily Xie, Katheryn A. Q. Cousins, Leslie M. Shaw, Sandhitsu R. Das, Jeffrey Maneval, Sara Manning, Christopher Brown, Katherine Lopez, Richard Keegan, Andrew Stephens, Corey T. McMillan, David J. Irwin, Liz Li, Ilya M. Nasrallah, and David A. Wolk: [18F]-PI-2620 uptake in the medial temporal lobes discriminates Alzheimer's disease from normal cognition and non-Alzheimer's dementias. Human Amyloid Imaging 2025.187 Shen, T., Vogel, J. W., Van Deerlin, V. M., Suh, E., Dratch, L., Phillips, J. S., Massimo, L., Lee, E. B., Irwin, D. J., & McMillan, C. T.: Disparate and shared transcriptomic signatures associated with cortical atrophy in genetic behavioral variant frontotemporal degeneration. Molecular Degeneration 20(1): 17, 2025.
18c Kim, B. J., Aleman, T. S., Cousins, K. A. Q., Daniel, E., Smith, E., Iacobucci, E., Kolomeyer, A., Hwang, C. K., McMillan, C. T., Van Deerlin, V. M., Phillips, J. S., Yu, Y., Ying, G.-S., & Irwin, D. J.: Choroidal evaluation of FTLD-Tau and biomarker-determined Alzheimer’s disease. Scientific Reports 15(1): 22290, 2025.
204 Watanabe, R., Papatriantafyllou, J. D., Maeda, K., Aguirre, G. K., Ando, M., Benoit, B., Grossman, M., Irwin, D. J., Kim, B., Massimo, L., McMillan, C. T., Papageorgiou, S. G., Phillips, J. S., Shiraishi, T., Sugihara, Y., Suh, E., Takashima, H., Toro, C., Van Deerlin, V. M., Nasrallah, I. M., and Lee, E. B.: Clinicopathological characterization of vacuolar tauopathy associated with VCP D395G. Alzheimer’s & Dementia 21(7): e70427, 2025.
1e3 Jesse S Cohen, Jeffrey Phillips, Sandhitsu R Das, Christopher A Olm, Hamsanandini Radhakrishnan, Emma Rhodes, Katheryn AQ Cousins, Sharon X Xie, Ilya M Nasrallah, Paul A Yushkevich, David A Wolk, Edward B Lee, Daniel Weintraub, David J Irwin, and Corey T McMillan: Posterior hippocampal sparing in Lewy body disorders with Alzheimer’s copathology: An in vivo MRI study. NeuroImage: Clinical 45(103714), 2025.
2b9 Katheryn Alexandra Quilico Cousins, David J Irwin, Thomas F Tropea, Emma Rhodes, Jeffrey S Phillips, Alice Chen-Plotkin, Michael C Brumm, Christopher S Coffey, Ju Hee Kang, Tanya Simuni, Tatiana Foroud, Arthur W Toga, Caroline M Tanner, Karl Kieburtz, Brit M Mollenhauer, Douglas R Galasko, Samantha Hutten, Daniel Weintraub, Andrew Siderowf, Kenneth Marek, Kathleen L Poston, Leslie M Shaw, Parkinson's Progression Marker Initiative: Evaluation of ATN-PD framework and biofluid markers to predict cognitive decline in early Parkinson's disease. Neurology 102(4): e208033, Feb 2024 Notes: doi: 10.1212/WNL.0000000000208033.
17c Jeffrey S. Phillips, John L. Robinson, Katheryn A. Q. Cousins, David A. Wolk, Edward B. Lee, Corey T. McMillan, John Q. Trojanowski, Murray Grossman, and David J. Irwin: Polypathologic associations with grey matter atrophy in neurodegenerative disease. Journal of Neuroscience 44(6): e0808232023, Feb 2024
178 Rhodes E, Mechanic-Hamilton D, Phillips JS, Bahena A, Vitali N, Hlava Q, Cook P, Gee J, Grossman M, McMillan C, Massimo L: Discrepancies in patient and caregiver ratings of personality change in Alzheimer’s disease and related dementias. Archives of Clinical Neuropsychology 39(4): 399-408, May 2024.
1aa Cousins, K.A., Phillips, J.S., Das, S.R., O'Brien, K., Tropea, T.F., Chen‐Plotkin, A., Shaw, L.M., Nasrallah, I.M., Mechanic‐Hamilton, D., McMillan, C.T. and Irwin, D.J.: Pathologic and cognitive correlates of plasma biomarkers in neurodegenerative disease. Alzheimer's & Dementia 20(6): 3889-3905, Apr 2024 Notes: https://doi.org/10.1002/alz.13777.
1b5 Arezoumandan S, Cousins KAQ, Ohm DT, Lowe M, Chen M, Gee J, Phillips JS, McMillan CT, Luk KC, Deik A, Spindler MA, Tropea TF, Weintraub D, Wolk DA, Grossman M, Lee V, Chen-Plotkin AS, Lee EB, Irwin DJ.: Tau maturation in the clinicopathological spectrum of Lewy body and Alzheimer's disease. Annals of Clinical and Translational Neurology 11(3): 673-685, Mar 2024.
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