Jessica Foster, MD
Assistant Professor of Pediatrics (Oncology)
Department: Pediatrics
Contact information
Children's Hospital of Philadelphia
Division of Oncology
Colket Translational Research Building, Rm. 3030
3501 Civic Center Boulevard
Philadelphia, PA 19104
Division of Oncology
Colket Translational Research Building, Rm. 3030
3501 Civic Center Boulevard
Philadelphia, PA 19104
Office: 267-425-1918
Fax: 267-426-0685
Fax: 267-426-0685
Email:
fosterjb@chop.edu
fosterjb@chop.edu
Publications
Education:
BA (Neuroscience and Behavior)
Columbia University, 2006.
MD
University of Virginia Medical School, 2010.
Permanent linkBA (Neuroscience and Behavior)
Columbia University, 2006.
MD
University of Virginia Medical School, 2010.
Description of Clinical Expertise
Pediatric neuro-oncologyDescription of Research Expertise
CAR T cells, pediatric brain tumors, mRNA therapeutics, liquid biopsySelected Publications
Ni H, Reitman ZJ, Zou W, Akhtar MN, Paul R, Huang M, Zhang D, Zheng H, Zhang R, Ma R, Ngo G, Zhang L, Diffenderfer ES, Motlagh SAO, Kim MM, Minn AJ, Dorsey JF, Foster JB, Metz J, Koumenis C, Kirsch DG, Gong Y, Fan Y.: FLASH radiation reprograms lipid metabolism and macrophage immunity and sensitizes medulloblastoma to CAR-T cell therapy. Nat Cancer Feb 2025.Fathi Kazerooni A, Kraya A, Rathi KS, Kim MC, Vossough A, Khalili N, Familiar AM, Gandhi D, Khalili N, Kesherwani V, Haldar D, Anderson H, Jin R, Mahtabfar A, Bagheri S, Guo Y, Li Q, Huang X, Zhu Y, Sickler A, Lueder MR, Phul S, Koptyra M, Storm PB, Ware JB, Song Y, Davatzikos C, Foster JB, Mueller S, Fisher MJ, Resnick AC, Nabavizadeh A.: Multiparametric MRI along with machine learning predicts prognosis and treatment response in pediatric low-grade glioma. Nat Commun 16: 340, Jan 2025.
Vitanza NA, Ronsley R, Choe M, Seidel K, Huang W, Rawlings-Rhea SD, Beam M, Steinmetzer L, Wilson AL, Brown C, Beebe A, Lindgren C, Gustafson JA, Wein A, Holtzclaw S, Hoeppner C, Goldstein HE, Browd SR, Hauptman JS, Lee A, Ojemann JG, Crotty EE, Leary SES, Perez FA, Wright JN, Alonso MM, Dun MD, Foster JB, Hurst D, Kong A, Thomsen A, Orentas RJ, Albert CM, Pinto N, Annesley C, Gardner RA, Ho O, Pattabhi S, Gust J, Wendler JP, Park JR, Jensen MC.: Intracerebroventricular B7-H3-targeting CAR T cells for diffuse intrinsic pontine glioma: a phase 1 trial. Nat Med Jan 2025.
Naqvi AS, Corbett RJ, Seghal P, Conkrite KL, Rathi KS, Ennis BM, Hayer KE, Zhang B, Brown MA, Miller DP, Kraya AA, Dybas JM, Geng Z, Blackden C, Arif S, Chroni A, Lahiri A, Hollawell ML, Storm PB, Foster JB, Koptyra M, Madsen PJ, Diskin SJ, Thomas-Tikhonenko A, Resnick AC, Rokita JL.: Characterization of aberrant splicing in pediatric central nervous system tumors reveals CLK1 as a candidate oncogenic dependency. bioRxiv Oct 2024.
Vitanza NA, Choe M, Brown C, Beebe A, Kong A, Rogers L, Jacob S, Mano E, Abuan K, Mgebroff S, Lindgren C, Gustafson JA, Wilson AL, Noll A, Ronsley R, Crotty EE, Leary SES, Foster JB, Pinto N, Gust J, Gardner RA, Park JR, Jensen MC.: Locoregional CAR T Cells for the Treatment of CNS Tumors in Children: Investigational Drug Service Pharmacy Activities. J Hematol Oncol Pharm 14(4): 148-154, Aug 2024.
Pascual-Pasto G, McIntyre B, Giudice AM, Alikarami F, Morrissey A, Matlaga S, Hofmann TJ, Burgueño V, Harvey K, Martinez D, Shah AC, Foster JB, Pogoriler J, Eagle RC, Carcaboso AM, Shields CL, Leahey AM, Bosse KR. : Targeting GPC2 on intraocular and CNS metastatic retinoblastomas with local and systemic delivery of CAR T-cells. Clin Cancer Res. June 2024 Notes: doi: 10.1158/1078-0432.CCR-24-0221.
Joshi N, Murugesan R, Beaubien E, McManus O, Wilson C,Harvey K, Mishra D, Hajeebu S, Madsen P, Foster J.: CARTART: A surface target identification tool for tumors. Neuro Oncol. 18(26 (Suppl 4)), Jun 2024.
Joshi N, Bagheri S, Beaubien E, Harvey K, McManus O, Wilson C, Hajeebu S, Mishra D, Nabavizadeh A, Madsen P, Foster J. : Genomic correlations with hemorrhage risk in pediatric patients with diffuse hemispheric glioma. Neuro Oncol. 18(26 (Suppl 4)), Jun 2024.
Harvey K, Al-atrache Z, McManus O, Dickson C, Patterson L, Beaubien E, Wilson C, Hajeebu S, Keil S, Braun M, Meechan M, Vitanza NA, Iliff J, Madsen P, Foster J. : Locoregional delivery of mRNA CAR T cell therapy into the cerebrospinal fluid in preclinical models of diffuse midline glioma. Neuro Oncol. 18(26 (Suppl 4)), Jun 2024.
Foster JB, Koptyra MP, Bagley SJ.: Recent Developments in Blood Biomarkers in Neuro-oncology. Curr Neurol Neurosci Rep 23(12): 857-867, Dec 2023.