1e
19
1
49
2
2
18
1b
1d
18
30
51
1d
2 29
1d
25
Jessica Foster, MD
88
51
Assistant Professor of Pediatrics (Oncology)
28
71
3
61
Attending Physician, Children’s Hospital of Philadelphia
11
Department: Pediatrics
4
1
b
1d
46
Contact information
51
4
3
3
1d
51
Children's Hospital of Philadelphia
1c Division of Oncology
38 Colket Translational Research Building, Rm. 3030
3e 3501 Civic Center Boulevard
Philadelphia, PA 19104
26
1c Division of Oncology
38 Colket Translational Research Building, Rm. 3030
3e 3501 Civic Center Boulevard
Philadelphia, PA 19104
2e
Office: 267-425-1918
32 Fax: 267-426-0685
24
83
32 Fax: 267-426-0685
24
Email:
fosterjb@chop.edu
12
fosterjb@chop.edu
18
Publications
23 a
3
2
29
4
b
1f
23 a
13
Education:
21 7 BA 26 (Neuroscience and Behavior) c
2c Columbia University, 2006.
21 7 MD c
3e University of Virginia Medical School, 2010.
c
3
3
3
3
8d
Permanent link21 7 BA 26 (Neuroscience and Behavior) c
2c Columbia University, 2006.
21 7 MD c
3e University of Virginia Medical School, 2010.
c
2 29
21
1e
1d
24
5e
71
e 29
27
Description of Clinical Expertise
28 Pediatric neuro-oncology71
Description of Research Expertise
55 CAR T cells, pediatric brain tumors, mRNA therapeutics, liquid biopsye 29
23
eb Binder ZA, Bagley SJ, Foster JB, O'Rourke DM. : The development of CAR T cells for patients with CNS malignancies. Nat Rev Clin Oncol. 32(2): 137-150, Feb 2026.
220 Naqvi AS, Sullivan PJ, Corbett RJ, Sehgal P, Conkrite KL, Rathi KS, Ennis BM, Hayer KE, Zhang B, Brown MA, Miller DP, Sickler A, Kraya AA, Coleman KL, Dybas JM, Geng Z, Blackden C, Arif S, Chroni A, Lahiri A, Hollawell ML, Storm PB, Haydar D, Foster JB, Koptyra M, Madsen PJ, Diskin SJ, Thomas-Tikhonenko A, Resnick AC, Rokita JL.: Alternative splicing in pediatric central nervous system tumors highlights oncofetal candidate CLK1 exon 4. Neurooncol Pediatr. Jan 2026.
ca Pan H, Foster JB, Bosse KR. : Scratching the surface of targeting GPC2 on pediatric CNS tumors. Mol Ther Oncol. 33(4), Dec 2025.
19f Song EZ, Timpanaro A, Meechan M, Elena-Sanchez L, Li LZ, Jamet S, Lau DS, Winter LI, Dun MD, Foster JB, Evans MK, Pattwell SS, Kalia V, Sarkar S, Jensen MC, Biery MC, Vitanza NA. : Engineered CXCR3-A expression enhances B7-H3-targeting CAR T cell migration and efficacy against diffuse intrinsic pontine glioma. Nat Commun. 16(1), Nov 2025.
240 Madsen PJ, Schlitter AM, Flemmig C, Dickson C, Harvey K, Wilson C, Beaubien E, Patterson L, Stern A, Griffin C, Joshi N, Hajeebu S, Martinez D, Storm PB, Resnick AC, Hillemanns P, Stanulla M, Faber J, Wingerter A, Gaida MM, Holtemeyer S, Laible M, Feldner A, Frohns F, Duarte JH, Sinn BV, Wöll S, Sahin U, Türeci Ö, Foster JB. : Claudin 6 is a suitable target for CAR T-cell therapy in atypical teratoid/rhabdoid brain tumors and other pediatric solid tumors. J Immunother Cancer. 13(10), Oct 2025.
1f3 Fathi Kazerooni A, Kraya A, Rathi KS, Kim MC, Kesherwani V, Corbett R, Vossough A, Khalili N, Gandhi D, Khalili N, Familiar AM, Jin R, Huang X, Zhu Y, Sickler A, Lueder MR, Phul S, Storm PB, Ware JB, Foster JB, Mueller S, Rokita JL, Fisher MJ, Resnick AC, Nabavizadeh A. : Imaging Clusters of Pediatric Low-Grade Glioma Are Associated with Distinct Molecular Characteristics. AJNR Am J Neuroradiol. 46(8): 1716-1725, Aug 2025.
22a Mikkelsen MK, Li X, Yu K, High AA, Tan H, Furtado LV, Leelatian N, Bell J, Berry JD, Boué DR, Chien F, Coven SL, Dewan MC, Fangusaro J, Foster JB, Hoffman L, Kofler JK, Larkin T, Lazow M, May A, Mobley BC, Noun D, Posorske B, Schwartz J, Sheila I, Spiller S, Tanaka R, Qaddoumi I, Tinkle CL, Peng J, Robinson GW, Moreira DC, Chiang J. : Diffuse leptomeningeal glioneuronal tumor (DLGNT): a comprehensive clinical and molecular analysis. Acta Neuropathol. 150(1): 18, August 2025.
1b6 Foster JB, Madsen PJ, Harvey K, Griffin C, Stern A, Patterson L, Joshi N, Dickson C, McManus O, Beaubien E, Wilson C, Beale DR, Baubet V, Goel P PN, Vitanza NA, Nazarian J, Koptyra M, Storm PB, Resnick AC. : Transient mRNA CAR T cells targeting GD2 provide dose-adjusted efficacy against diffuse midline glioma and high grade glioma models. Neuro Oncol. May 2025.
13a Timpanaro A, Song EZ, Amwas N, Chiu CH, Ronsley R, Taylor MR, Foster JB, Wang LD, Vitanza NA.: Evolving CAR T-Cell Therapy to Overcome the Barriers in Treating Pediatric Central Nervous System Tumors. Cancer Discov. 15(5): 890-902, May 2025.
2c
7
1d
1f
Selected Publications
1d6 Timpanaro A, Song EZ, Toumi R, Elena-Sanchez L, Piccand C, Nemec K, Kordowski A, Lau D, Johnson S, Winter L, Rajendran A, Ronsley R, Oda SK, Gustafson J, Wendler JP, Koschmann C, Evans M, Pattwell S, Jensen MC, Foster JB, Dun MD, Meechan M, Biery MC, Vitanza NA. : Preclinical efficacy of combinatorial B7-H3 CAR T cells and ONC206 against diffuse intrinsic pontine glioma. Neuro Oncol. Feb 2026.eb Binder ZA, Bagley SJ, Foster JB, O'Rourke DM. : The development of CAR T cells for patients with CNS malignancies. Nat Rev Clin Oncol. 32(2): 137-150, Feb 2026.
220 Naqvi AS, Sullivan PJ, Corbett RJ, Sehgal P, Conkrite KL, Rathi KS, Ennis BM, Hayer KE, Zhang B, Brown MA, Miller DP, Sickler A, Kraya AA, Coleman KL, Dybas JM, Geng Z, Blackden C, Arif S, Chroni A, Lahiri A, Hollawell ML, Storm PB, Haydar D, Foster JB, Koptyra M, Madsen PJ, Diskin SJ, Thomas-Tikhonenko A, Resnick AC, Rokita JL.: Alternative splicing in pediatric central nervous system tumors highlights oncofetal candidate CLK1 exon 4. Neurooncol Pediatr. Jan 2026.
ca Pan H, Foster JB, Bosse KR. : Scratching the surface of targeting GPC2 on pediatric CNS tumors. Mol Ther Oncol. 33(4), Dec 2025.
19f Song EZ, Timpanaro A, Meechan M, Elena-Sanchez L, Li LZ, Jamet S, Lau DS, Winter LI, Dun MD, Foster JB, Evans MK, Pattwell SS, Kalia V, Sarkar S, Jensen MC, Biery MC, Vitanza NA. : Engineered CXCR3-A expression enhances B7-H3-targeting CAR T cell migration and efficacy against diffuse intrinsic pontine glioma. Nat Commun. 16(1), Nov 2025.
240 Madsen PJ, Schlitter AM, Flemmig C, Dickson C, Harvey K, Wilson C, Beaubien E, Patterson L, Stern A, Griffin C, Joshi N, Hajeebu S, Martinez D, Storm PB, Resnick AC, Hillemanns P, Stanulla M, Faber J, Wingerter A, Gaida MM, Holtemeyer S, Laible M, Feldner A, Frohns F, Duarte JH, Sinn BV, Wöll S, Sahin U, Türeci Ö, Foster JB. : Claudin 6 is a suitable target for CAR T-cell therapy in atypical teratoid/rhabdoid brain tumors and other pediatric solid tumors. J Immunother Cancer. 13(10), Oct 2025.
1f3 Fathi Kazerooni A, Kraya A, Rathi KS, Kim MC, Kesherwani V, Corbett R, Vossough A, Khalili N, Gandhi D, Khalili N, Familiar AM, Jin R, Huang X, Zhu Y, Sickler A, Lueder MR, Phul S, Storm PB, Ware JB, Foster JB, Mueller S, Rokita JL, Fisher MJ, Resnick AC, Nabavizadeh A. : Imaging Clusters of Pediatric Low-Grade Glioma Are Associated with Distinct Molecular Characteristics. AJNR Am J Neuroradiol. 46(8): 1716-1725, Aug 2025.
22a Mikkelsen MK, Li X, Yu K, High AA, Tan H, Furtado LV, Leelatian N, Bell J, Berry JD, Boué DR, Chien F, Coven SL, Dewan MC, Fangusaro J, Foster JB, Hoffman L, Kofler JK, Larkin T, Lazow M, May A, Mobley BC, Noun D, Posorske B, Schwartz J, Sheila I, Spiller S, Tanaka R, Qaddoumi I, Tinkle CL, Peng J, Robinson GW, Moreira DC, Chiang J. : Diffuse leptomeningeal glioneuronal tumor (DLGNT): a comprehensive clinical and molecular analysis. Acta Neuropathol. 150(1): 18, August 2025.
1b6 Foster JB, Madsen PJ, Harvey K, Griffin C, Stern A, Patterson L, Joshi N, Dickson C, McManus O, Beaubien E, Wilson C, Beale DR, Baubet V, Goel P PN, Vitanza NA, Nazarian J, Koptyra M, Storm PB, Resnick AC. : Transient mRNA CAR T cells targeting GD2 provide dose-adjusted efficacy against diffuse midline glioma and high grade glioma models. Neuro Oncol. May 2025.
13a Timpanaro A, Song EZ, Amwas N, Chiu CH, Ronsley R, Taylor MR, Foster JB, Wang LD, Vitanza NA.: Evolving CAR T-Cell Therapy to Overcome the Barriers in Treating Pediatric Central Nervous System Tumors. Cancer Discov. 15(5): 890-902, May 2025.
2c