Jessica Foster, MD

faculty photo
Assistant Professor of Pediatrics (Oncology)
Department: Pediatrics

Contact information
Children's Hospital of Philadelphia
Division of Oncology
Colket Translational Research Building, Rm. 3030
3501 Civic Center Boulevard
Philadelphia, PA 19104
Office: 267-425-1918
Fax: 267-426-0685
Education:
BA (Neuroscience and Behavior)
Columbia University, 2006.
MD
University of Virginia Medical School, 2010.
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Description of Clinical Expertise

Pediatric neuro-oncology

Description of Research Expertise

CAR T cells, pediatric brain tumors, mRNA therapeutics

Selected Publications

Foster JB, Alonso MM, Sayour E, Davidson TB, Persson ML, Dun MD, Kline C, Mueller S, Vitanza NA, van der Lugt J.: : Translational considerations for immunotherapy clinical trials in pediatric neuro-oncology. Neoplasia 42, August 2023 Notes: doi: 10.1016/j.neo.2023.100909 Epub 2023 May 25.

Foster JB, Madsen P, Harvey K, Patterson L, Griffin C, Stern A, Storm PB, Resnick AC. : Targeting GD2 in thalamic diffuse midline glioma with transient mRNA CAR T cells. SNO 7th Biennial Pediatric Neuro-Oncology Research Conference. June 2023 Notes: Washington DC.

Madsen PJ, Stern A, Dickson C, Wilson C, Patterson L, Harvey K, Griffin C, Oehm P, Rengstl B, Flemmig C, Storm PB, Resnick AC, Foster JB. : CAR T cell therapy targeting claudin-6 is effective in cellular and xenograft models of atypical teratoid/rhabdoid tumor. SNO 7th Biennial Pediatric Neuro-Oncology Research Conference. June 2023 Notes: Washington DC.

Harvey K, Madsen PJ, Smith T, Griffin C, Patterson L, Vitanza NA, Storm PB, Resnick AC, Foster JB. : Development of an intracranial cannula implantation system for serial locoregional CAR T cell infusions in mice. SNO 7th Biennial Pediatric Neuro-Oncology Research Conference. June 2023 Notes: Washington DC.

Harvey K, Madsen PJ, Smith T, Griffin C, Patterson L, Vitanza NA, Storm PB, Resnick AC, Foster JB. : Intracranial Cannula Implantation for Serial Locoregional Chimeric Antigen Receptor (CAR) T Cell Infusions in Mice. J Vis Exp. 24(192), February 2023 Notes: doi: 10.3791/64886.

Vitanza NA, Ronsley R, Choe M, Henson C, Breedt M, Barrios-Anderson A, Wein A, Brown C, Beebe A, Kong A, Kirkey D, Lee BM, Leary SES, Crotty EE, Hoeppner C, Holtzclaw S, Wilson AL, Gustafson JA, Foster JB, Iliff JJ, Goldstein HE, Browd SR, Lee A, Ojemann JG, Pinto N, Gust J, Gardner RA, Jensen MC, Hauptman JS, Park JR. : Locoregional CAR T cells for children with CNS tumors: Clinical procedure and catheter safety. Neoplasia 36(100870), February 2023 Notes: Epub 2023 Jan 3. doi: 10.1016/j.neo.2022.100870.

Madsen PJ, Hollawell ML, Santi M, Surrey LF, Vossough A, Orr BA, Hill-Kayser C, Tucker AM, Storm PB, Foster JB. : Diffuse leptomeningeal glioneuronal tumor in a child masquerading as an intramedullary spinal pilocytic astrocytoma. Neurooncol Adv. 5(1), January - December 2023 Notes: doi: 10.1093/noajnl/vdad049. eCollection.

Vitanza NA, Wilson AL, Huang W, Seidel K, Brown C, Gustafson JA, Yokoyama JK, Johnson AJ, Baxter BA, Koning RW, Reid AN, Meechan M, Biery MC, Myers C, Rawlings-Rhea SD, Albert CM, Browd SR, Hauptman JS, Lee A, Ojemann JG, Berens ME, Dun MD, Foster JB, Crotty EE, Leary SES, Cole BL, Perez FA, Wright JN, Orentas RJ, Chour T, Newell EW, Whiteaker JR, Zhao L, Paulovich AG, Pinto N, Gust J, Gardner RA, Jensen MC, Park JR.: Intraventricular B7-H3 CAR T Cells for Diffuse Intrinsic Pontine Glioma: Preliminary First-in-Human Bioactivity and Safety. Cancer Discov. 13(1): 114-131, January 2023.

Foster JB, Griffin C, Rokita JL, Stern A, Brimley C, Rathi K, Lane MV, Buongervino SN, Smith T, Madsen PJ, Martinez D, Delaidelli A, Sorensen PH, Wechsler-Reya RJ, Karikó K, Storm PB, Barrett DM, Resnick AC, Maris JM, Bosse KR. : Development of GPC2-directed chimeric antigen receptors using mRNA for pediatric brain tumors. J Immunother Cancer 10(9), September 2022.

Naqvi A, Ennis B, Jin R, Gaonkar K. Foster J, Conkrite K, Rathi K, Kraya A, Sonawane P, Madsen P, Storm P, Resnick A, Rokita JL: CLK1 aberrant splicing in pediatric high-grade gliomas disrupts key oncogenic transcriptional programs. Neuro-Oncology 24(Issue Supplement 1): i74, June 2022.

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Last updated: 07/11/2023
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