Vinodh Pillai, M.D., Ph.D.
Associate Professor of Pathology and Laboratory Medicine at the Children's Hospital of Philadelphia
Hematopathologist, Hospital of the University of Pennsylvania
Member, Center for Childhood Cancer Research
Department: Pathology and Laboratory Medicine
Contact information
3401 Civic Center Blvd,
Department of Pathology and Laboratory Medicine
Philadelphia, PA 19104
Department of Pathology and Laboratory Medicine
Philadelphia, PA 19104
Fax: 215-590-1736
Publications
Education:
M.B.B.S. (Medicine and Surgery)
Madras Medical College, 2002.
Ph.D. (Biomedical sciences, Immunology)
University of Texas Southwestern Medical Center , 2007.
Permanent linkM.B.B.S. (Medicine and Surgery)
Madras Medical College, 2002.
Ph.D. (Biomedical sciences, Immunology)
University of Texas Southwestern Medical Center , 2007.
Description of Clinical Expertise
Hematopoietic neoplasmsPathology of CAR T cell therapy in B-ALL
Description of Research Expertise
CAR T cell therapyAcute lymphoblastic leukemia
Castleman disease
Kikuchi-Fujimoto lymphadenitis
Single cell sequencing of pediatric lymphoma
Spatial transcriptomics
Selected Publications
Pillai V: CAR-T — The Slow and the Spurious. Elsevier 31(3): 121-122, March 2025 Notes: https://doi.org/10.1016/j.jtct.2025.02.007.Sahasrabuddhe AA, Chen X, Ma K, Wu R, Liang HC, Kapoor R, Chhipa RR, Onder O, McFetridge C, Van Arnam JS, Zhang X, Morrissette JJD, Pillai V, Li MM, Szankasi P, Basrur V, Conlon KP, Raabe TD, Bailey NG, Hogaboam CM, Rottapel R, Kim J, López C, Schlesner M, Siebert R, Dreval K, Morin RD, Moro L, Pagano M, Staudt LM, Lim MS, Elenitoba-Johnson KSJ: The FBXO45-GEF-H1 Axis Controls Germinal Center Formation and B-cell Lymphomagenesis. Cancer Discov January 2025 Notes: Online ahead of print.
Koga S, Tirado F, Pillai V, Lee FS, and Cooper K: Incidental Autopsy Finding of Retiform Hemangioendothelioma of the Spleen Formosan Journal of Surgery 58(1): 34-35, January 2025.
Smith D, Eichinger A, Rech A, Wang J, Esteva E, Seyedian A, Yang X, Zhang M, Martinez D, Tan K, Luo M, Park C, Reizis B, Pillai V: Spatial and Single Cell Mapping of Castleman Disease Reveals Key Stromal Cell Types and Cytokine Pathways. bioRxiv September 2024 Notes: Online ahead of Print. https://doi.org/10.1101/2024.09.09.609717 https://www.biorxiv.org/content/10.1101/2024.09.09.609717v1.
Patel R, Ghilardi G, Zhang Y, Chiang YH, Xie W, Guruprasad P, Kim KH, Chun I, Angelos MG, Pajarillo R, Hong SJ, Lee YG, Shestova O, Shaw C, Cohen I, Gupta A, Vu T, Qian D, Yang S, Nimmagadda A, Snook AE, Siciliano N, Rotolo A, Inamdar A, Harris J, Ugwuanyi O, Wang M, Carturan A, Paruzzo L, Chen L, Ballard HJ, Blanchard T, Xu C, Abdel-Mohsen M, Gabunia K, Wysocka M, Linette GP, Carreno B, Barrett DM, Teachey DT, Posey AD, Powell Jr DJ, Sauter CT, Pileri S, Pillai V, Scholler J, Rook AH, Schuster SJ, Barta SK, Porazzi P, Ruella M: CD5 Deletion Enhances the Antitumor Activity of Adoptive T Cell Therapies. Sci Immunol 9(97), July 2024.
Bandyopadhyay S, Duffy M, Jin Ahn K, Pang M, Smith D, Duncan G, Sussman J, Zhang I, Huang J, Lin Y, Xiong B, Imtiaz T, Chen CH, Thadi A, Chen C, Xu J, Reichart M, Pillai V, Snaith O, Oldridge D, Bhattacharyya S, Maillard I, Carroll M, Nelson C, Qin L, Tan K: Mapping the Cellular Biogeography of Human Bone Marrow Niches Using Single-Cell Transcriptomics and Proteomic Imaging. Cell 187(12): 3120-3140. June 2024.
Le Coz C, Trofa M, Yoon S, Tian T, Reid W, Cabrera EC, Knox A, Khanna C, Sullivan K, Heimall J, Takach P, Fadugba OO, Lawrence M, Jyonouchi1 S, Hakonarson H, Wells A, Handler S, Zur K, Pillai V, Gildersleeve JC, Romberg N: The Common Variable Immunodeficiency IgM Repertoire Narrowly Recognizes Erythrocyte and Platelet Glycans. Journal of Allergy and Clinical Immunology April 2024 Notes: Online ahead of print
Bandyopadhyay S, Duffy M, Ahn KJ, Pang M, Smith D, Duncan G, Sussman J, Zhang I, Huang J, Lin Y, Xiong B, Imtiaz T, Chen C, Thadi A, Chen C, Xu J, Reichart M, Pillai V, Snaith O, Oldridge D, Bhattacharyya S, Maillard I, Carroll M, Nelson C, Qin L, Tan K: Mapping the Cellular Biogeography of Human Bone Marrow Niches Using Single-Cell Transcriptomics and Proteomic Imaging. 65th ASH Meeting and Exposition December 2023.
Anil J, Alnemri A, Lytle A, Lockhart B, Anil AE, Baumgartner M, Gebre K, McFerran J, Grupp SA, Rheingold SR, Pillai V: Bone Marrow Fibrosis is Associated with Non-Response to CD19 CAR T-Cell Therapy in B-Acute Lymphoblastic Leukemia. Am J Hematol 98(12): 1888-1897, December 2023.
Fenu E, Margolskee E, Pillai V: Transdifferentiation of B-lymphoblastic Leukemia to Histiocytic Sarcoma After Immunotherapy. American journal of hematology 98(8): E216-E218, August 2023.