Vinodh Pillai, M.D., Ph.D.
Associate Professor of Pathology and Laboratory Medicine at the Children's Hospital of Philadelphia
Hematopathologist, Hospital of the University of Pennsylvania
Member, Center for Childhood Cancer Research
Department: Pathology and Laboratory Medicine
Contact information
3401 Civic Center Blvd,
Department of Pathology and Laboratory Medicine
Philadelphia, PA 19104
Department of Pathology and Laboratory Medicine
Philadelphia, PA 19104
Fax: 215-590-1736
Publications
Education:
M.B.B.S. (Medicine and Surgery)
Madras Medical College, 2002.
Ph.D. (Biomedical sciences, Immunology)
University of Texas Southwestern Medical Center , 2007.
Permanent linkM.B.B.S. (Medicine and Surgery)
Madras Medical College, 2002.
Ph.D. (Biomedical sciences, Immunology)
University of Texas Southwestern Medical Center , 2007.
Description of Clinical Expertise
Hematopoietic neoplasmsPathology of CAR T cell therapy in B-ALL
Description of Research Expertise
CAR T cell therapyAcute lymphoblastic leukemia
Castleman disease
Kikuchi-Fujimoto lymphadenitis
Single cell sequencing of pediatric lymphoma
Spatial transcriptomics
Selected Publications
Carturan A, Angelos MG, Guruprasad P, Patel RP, Pajarillo R, Lee AE, Espie D, Zhang Y, Chiang YH, Xie W, Rodriguez JL, Harris J, Devi P, Afolayan-Oloye OI, Xu J, Sussman JH, Elghawy O, Yang AG, Barsouk A, Cho JH, Shaw CE, Singh EB, Ugwuanyi O, Paruzzo L, Stella FMD, Liu S, Nason S, Imparato A, Rotolo A, Lemoine J, Barrett DM, Posey AD Jr, Rook AH, Pillai V, Bagg A, Pileri SA, Liu D, Tan K, Schuster SJ, Teachey DT, Porazzi P, Ruella M: Harnessing the CD2 axis to broaden and enhance the efficacy of CAR T-cell therapies. Blood. American Society of Hematology, January 2026.Ang Z, Castro A, Paruzzo L, Schmidt C, Hasanali ZS, Hayer KE, Stella F, Soldan SS, Torres-Diz M, Kwok C, Sainos PK, Ji K, Krohl PJ, Fine J, Sehgal P, Martinez D, Spangler JB, Riley JL, Vogl DT, Porazzi P, Pillai V, Lieberman PM, Allman D, Ruella M, Thomas-Tikhonenko A: The ancestral haplotype of P2RX5 yields a B-cell surface marker and a multi-lineage immunotherapy target. bioRxiv. Cold Spring Harbor Laboratory, January 2026.
James ER, Salmeron-Villalobos J, Colmenero A, Frauenfeld L, Andres M, Verdu J, Garcia N, Simonitsch-Klupp I, Attarbaschi A, Bacon CM, Burke GA, Lockhart B, Ducray SP, Chen Z, Tizioni MM, Matthews JD, Steel C, Pillon M, Lussolin A, Pervez S, Pillai V, Štěrba J, Krenova Z, Aven M, Wrobel G, Werner J, Knorr F, Oschlies I, Klapper W, Woessmann W, Balague O, Salaverria I, Turner SD: 090 – Pediatric ALK-negative anaplastic large cell lymphoma genetically differs from the adult counterpart. Leukemia Research. Elsevier, 156(Supplement): Abstract 090, September 2025 Notes: Poster presentation abstract. Eighth International Symposium on Childhood, Adolescent and Young Adult Non-Hodgkin Lymphoma.
Smith D, Eichinger A, Fennell É, Xu-Monette ZY, Rech A, Wang J, Esteva E, Seyedian A, Yang X, Zhang M, Martinez D, Tan K, Luo M, Young KJ, Murray PG, Park C, Reizis B, Pillai V: Spatial and single cell mapping of castleman disease reveals key stromal cell types and cytokine pathways. Nat Commun 16(1): 6009, July 2025.
Julia Wang, Brian Lockhart, Jason Xu, Vinodh Pillai: RNA-seq of seven non-neoplastic/inflammatory lymphadenitis entities identify potential molecular diagnostic markers bioRxiv May 2025 Notes: https://doi.org/10.1101/2025.05.29.655793.
Pillai V.: CAR-T - The Slow and the Spurious. Transplant Cell Ther. 31(3): 121-122, March 2025.
Pillai V: CAR-T — The Slow and the Spurious. Elsevier 31(3): 121-122, March 2025 Notes: https://doi.org/10.1016/j.jtct.2025.02.007.
Li D, Tasian SK, Wertheim G, Rheingold SR, Bernt KM, Newman H, Wainwright L, Wilmoth DM, Thiel B, Surrey LF, Margolskee E, Pillai V, Luo M, Paessler ME, Hunger SP, Li MM, Zhong Y: Integrated genomic analysis to reduce chromosomal analysis for the diagnosis of pediatric hematologic malignancies: addressing the shortage of cytogenetic technologists. Haematologica January 2025.
Koga S, Tirado F, Pillai V, Lee FS, and Cooper K: Incidental Autopsy Finding of Retiform Hemangioendothelioma of the Spleen Formosan Journal of Surgery 58(1): 34-35, January 2025.
Sahasrabuddhe AA, Chen X, Ma K, Wu R, Liang HC, Kapoor R, Chhipa RR, Onder O, McFetridge C, Van Arnam JS, Zhang X, Morrissette JJD, Pillai V, Li MM, Szankasi P, Basrur V, Conlon KP, Raabe TD, Bailey NG, Hogaboam CM, Rottapel R, Kim J, López C, Schlesner M, Siebert R, Dreval K, Morin RD, Moro L, Pagano M, Staudt LM, Lim MS, Elenitoba-Johnson KSJ: The FBXO45-GEF-H1 Axis Controls Germinal Center Formation and B-cell Lymphomagenesis. Cancer Discov January 2025 Notes: Online ahead of print.