Vinodh Pillai, M.D., Ph.D.

faculty photo
Assistant Professor of Pathology and Laboratory Medicine at the Children's Hospital of Philadelphia
Hematopathologist, Hospital of the University of Pennsylvania
Member, Center for Childhood Cancer Research
Department: Pathology and Laboratory Medicine

Contact information
3401 Civic Center Blvd,
Department of Pathology and Laboratory Medicine
Philadelphia, PA 19104
Fax: 215-590-1736
Education:
M.B.B.S. (Medicine and Surgery)
Madras Medical College, 2002.
Ph.D. (Biomedical sciences, Immunology)
University of Texas Southwestern Medical Center , 2007.
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Description of Clinical Expertise

Hematopoietic neoplasms
Pathology of CAR T cell therapy in B-ALL

Description of Research Expertise

CAR T cell therapy
Acute lymphoblastic leukemia
Castleman disease
Kikuchi-Fujimoto lymphadenitis
Single cell sequencing of pediatric lymphoma
Spatial transcriptomics

Selected Publications

Hurwitz S, Lockhart B, Önder Ö, Wu R, Pillai V, Elenitoba-Johnson K, Lim MS: Proteogenomic Profiling of High-Grade B-Cell Lymphoma with 11q Aberration and Burkitt Lymphoma Reveals LEF1 as a Novel Biomarker. United States and Canadian Academy of Pathology 2023 New Orleans, Louisiana March 2023 Notes: Oral Presentation.

Ren J, Xing B, O’Keefe RA, Lv K, Wang R, Bauer K, Ghazaryan A, Burslem GM, Zhang J, O'Connell R, Pillai V, Hexner E, Philips M, Tong W: RAB27B Controls Palmitoylation Dependent NRAS Trafficking and Signaling in Leukemia. Journal of Clinical Investigation March 2023.

Lockhart B, Vincent T, Paessler M, Pillai V: Transcriptomics Reveal Genes and Pathways in Sinus Histiocytosis, Autoimmune Lymphoproliferative Syndrome and Rosai Dorfman Disease. United States and Canadian Academy of Pathology 2023 New Orleans, Louisiana March 2023 Notes: Poster Presentation.

Alnemri A, Lockhart B, Anil J, Baumgartner M, Pillai V: Genes and Signaling Pathways Associated with Bone Marrow Fibrosis in B-Lymphoblastic Leukemia. United States and Canadian Academy of Pathology 2023 New Orleans, Louisiana March 2023 Notes: Poster Presentation.

Pillai V, Smith D, Eichinger A, Seyedian A, Park CY, Tan K, Reizis B: Single Cell Multi-Omics Reveals Unique Populations, Cell Interactions and Signaling Pathways that Underlie Kikuchi-Fujimoto Disease. United States and Canadian Academy of Pathology 2023 New Orleans, Louisiana March 2023 Notes: Poster Presentation.

Kirtek T, Hamdan H, Van Arnam JS, Park S, Kovach AE, Pillai V, Weinberg OK: Spontaneous remission of acute lymphoblastic leukemia: A series of 9 cases and a review of literature. International Journal of Laboratory Hematology February 2023 Notes: Online Ahead of Print.

Ang Z, Hayer KE, Diz MT, Schmidt C, Zheng S, Xu F, Falkenstein CD, Loftus JP, Yang SY, Asnani M, Pillai V, Chong E, Li MM, Tasian SK, Barash Y, Schuster SJ, Thomas-Tikhonenko A: Alternative splicing of its 5' untranslated region controls CD20 mRNA translation and enables resistance to CD20-directed immunotherapies. Biorxiv February 2023.

Zhu G, Inam Z, Calleroz A, Pillai V, Schore R, and Cheng J: Pediatric Acute Erythroid Leukemias with Monocytic Antigen Expression and Novel Chromosomal Translocations. Pediatric Blood & Cancer 2023.

Anil J, Lytle A, Alnemri A, Lockhart B, Pillai V: Bone Marrow Fibrosis Is Associated with Non-Response to CD19 CAR-T Therapy. 64th ASH Annual Meeting and Exposition December 2022 Notes: Poster Presentation.

Yang S, Hayer K, Fazelinia H, Spruce L, Asnani M, Black K, Naqvi A, Pillai V, Barash Y, Elenitoba-Johnson K, Thomas-Tikhonenko A: FBXW7β Isoform Drives Transcriptional Activation of a Proinflammatory TNF Cluster in Human pro-B Cells. Blood Advances November 2022 Notes: Online ahead of print.

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Last updated: 03/27/2023
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