Vinodh Pillai, M.D., Ph.D.

Associate Professor of Pathology and Laboratory Medicine at the Children's Hospital of Philadelphia
Hematopathologist, Hospital of the University of Pennsylvania
Member, Center for Childhood Cancer Research
Department: Pathology and Laboratory Medicine
Contact information
3401 Civic Center Blvd,
Department of Pathology and Laboratory Medicine
Philadelphia, PA 19104
Department of Pathology and Laboratory Medicine
Philadelphia, PA 19104
Fax: 215-590-1736
Publications
Education:
M.B.B.S. (Medicine and Surgery)
Madras Medical College, 2002.
Ph.D. (Biomedical sciences, Immunology)
University of Texas Southwestern Medical Center , 2007.
Permanent linkM.B.B.S. (Medicine and Surgery)
Madras Medical College, 2002.
Ph.D. (Biomedical sciences, Immunology)
University of Texas Southwestern Medical Center , 2007.
Description of Clinical Expertise
Hematopoietic neoplasmsPathology of CAR T cell therapy in B-ALL
Description of Research Expertise
CAR T cell therapyAcute lymphoblastic leukemia
Castleman disease
Kikuchi-Fujimoto lymphadenitis
Single cell sequencing of pediatric lymphoma
Spatial transcriptomics
Selected Publications
Bandyopadhyay S, Duffy M, Ahn KJ, Pang M, Smith D, Duncan G, Sussman J, Zhang I, Huang J, Lin Y, Xiong B, Imtiaz T, Chen C, Thadi A, Chen C, Xu J, Reichart M, Pillai V, Snaith O, Oldridge D, Bhattacharyya S, Maillard I, Carroll M, Nelson C, Qin L, Tan K: Mapping the Cellular Biogeography of Human Bone Marrow Niches Using Single-Cell Transcriptomics and Proteomic Imaging. 65th ASH Meeting and Exposition December 2023.Fenu E, Margolskee E, Pillai V: Transdifferentiation of B-lymphoblastic Leukemia to Histiocytic Sarcoma After Immunotherapy. American journal of hematology 98(8): E216-E218, August 2023.
Ang Z, Paruzzo L, Hayer KE, Schmidt C, Diz MT, Xu F, Zankharia U, Zhang Y, Soldan S, Zheng S, Falkenstein CD, Loftus JP, Yang SY, Asnani M, Sainos PK, Pillai V, Chong E, Li MM, Tasian SK, Barash Y, Lieberman PM, Ruella M, Schuster SJ, Thomas-Tikhonenko A: Alternative Splicing of Its 5' UTR Limits CD20 mRNA Translation and Enables Resistance to CD20-directed Immunotherapies. Blood August 2023 Notes: Online Ahead Of Print.
Ren J, Xing B, O’Keefe RA, Lv K, Wang R, Bauer K, Ghazaryan A, Burslem GM, Zhang J, O'Connell R, Pillai V, Hexner E, Philips M, Tong W: RAB27B Controls Palmitoylation Dependent NRAS Trafficking and Signaling in Leukemia. Journal of Clinical Investigation 133(12): e165510, June 2023.
Zhu G, Inam Z, Calleroz A, Pillai V, Schore R, and Cheng J: Pediatric Acute Erythroid Leukemias with Monocytic Antigen Expression and Novel Chromosomal Translocations. Pediatric Blood & Cancer 19, April 2023 Notes: Online ahead of print.
Hurwitz S, Lockhart B, Önder Ö, Wu R, Pillai V, Elenitoba-Johnson K, Lim MS: Proteogenomic Profiling of High-Grade B-Cell Lymphoma with 11q Aberration and Burkitt Lymphoma Reveals LEF1 as a Novel Biomarker. United States and Canadian Academy of Pathology 2023 New Orleans, Louisiana March 2023 Notes: Oral Presentation.
Hurwitz S, Lockhart B, Önder Ö, Wu R, Sethi S, Aypar U, Siebert R, Dogan A, Pillai V, Elenitoba-Johnson K, Lim MS: Proteogenomic Profiling of High-Grade B-Cell Lymphoma with 11q Aberration and Burkitt Lymphoma Reveals LEF1 as a Novel Biomarker Modern Pathology 36(7), March 2023 Notes: Online Ahead of Print.
Lockhart B, Vincent T, Paessler M, Pillai V: Transcriptomics Reveal Genes and Pathways in Sinus Histiocytosis, Autoimmune Lymphoproliferative Syndrome and Rosai Dorfman Disease. United States and Canadian Academy of Pathology 2023 New Orleans, Louisiana March 2023 Notes: Poster Presentation.
Alnemri A, Lockhart B, Anil J, Baumgartner M, Pillai V: Genes and Signaling Pathways Associated with Bone Marrow Fibrosis in B-Lymphoblastic Leukemia. United States and Canadian Academy of Pathology 2023 New Orleans, Louisiana March 2023 Notes: Poster Presentation.
Pillai V, Smith D, Eichinger A, Seyedian A, Park CY, Tan K, Reizis B: Single Cell Multi-Omics Reveals Unique Populations, Cell Interactions and Signaling Pathways that Underlie Kikuchi-Fujimoto Disease. United States and Canadian Academy of Pathology 2023 New Orleans, Louisiana March 2023 Notes: Poster Presentation.