Vinodh Pillai, M.D., Ph.D.

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Assistant Professor of Pathology and Laboratory Medicine at the Children's Hospital of Philadelphia
Department: Pathology and Laboratory Medicine

Contact information
The Children's Hospital of Philadelphia
Department of Pathology and Laboratory Medicine
5th Floor Main Building - Room 5199B
Philadelphia, PA 19104
Fax: 215-590-1736
Education:
M.B.B.S. (Medicine and Surgery)
Madras Medical College, 2002.
Ph.D. (Biomedical sciences Immunology)
University of Texas Southwestern Medical Center , 2007.
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Description of Clinical Expertise

Pediatric Hematopathology including leukemias and lymphomas
Pathology of CAR T cell therapy in B-ALL

Description of Research Expertise

CAR T cell therapy
Pediatric hematopoietic malignancies
Acute lymphoblastic leukemia
Castleman disease
Juvenile myelomonocytic leukemia
Kikuchi-Fujimoto lymphadenitis

Selected Publications

Lytle A, Pillai V, Wertheim GW, Paessler M, Croy C and Rheingold S: Blinatumomab Induces Bone Marrow Lymphoid Infiltrates That Correlate with Response in B-ALL. United States and Canadian Academy of Pathology 2021 Baltimore, Maryland March 2021.

Wei J, Faude S, Xu X, Wertheim G, Paessler M, Bhoj V, Pillai V: Morphological and Immunophenotypic Characterization of CAR T Cells. United States and Canadian Academy of Pathology 2021 Baltimore, Maryland March 2021.

Nya D Nelson 1 2, Wenzhao Meng 1, Aaron M Rosenfeld 1, Susan Bullman 3 4 5, Chandra Sekhar Pedamallu 3 4 5, Jason L Nomburg 3 4 5, Gerald B Wertheim 2, Michele E Paessler 1 2, Geraldine Pinkus 5, Jason L Hornick 5, Matthew Meyerson 3 4 5, Eline T Luning Prak 1, Vinodh Pillai: Characterization of Plasmacytoid Dendritic Cells, Microbial Sequences, and Identification of a Candidate Public T-Cell Clone in Kikuchi-Fujimoto Disease. Pediatr Dev Pathol. Feb 2 2021.

Zhao X, Kotch C, Fox E, Surrey L, Wertheim GB, Baloch ZW, Lin F, P:illai V, Luo M, Kreiger PA, Pogoriler JE, Linn RL, Russo PA, Santi M, Resnick AC, Storm PB, Hunger SP, Bauer AJ and Li MM: NTRK Fusions Identified in Pediatric Tumors: The Frequency, Fusion Partners, and Clinical Outcome. JCO Precision Oncology Page: 204-214, January 2021.

Sophia Faude, Jane Wei, Kavitha Muralidharan, Xiaoming Xu, Gerald Wertheim, Michele Paessler, Vijay G. Bhoj, Stephan A. Grupp, Shannon L. Maude, Susan R. Rheingold, and Vinodh Pillai: Absolute Lymphocyte Count Kinetics after CAR T Cell Infusion Impacts Response and Relapse. Blood Advances (in press) 2021.

Jung-Yeon Lim, Sascha Duttke, Turner Baker, Jihye Lee, Kristyne Gambino, Nicholas Venturini, Jessica Sook Yuin Ho, Simin Zheng, Yesai Fstkchyan, Vinodh Pillai, David Fajgenbaum, Ivan Marazzi, Christopher Benner, and Minji Byun: DNMT3A haploinsufficiency causes dichotomous DNA methylation defects at enhancers in mature human immune cells Journal of Experimental Medicine in press 2021.

Hupp MM, Bashleben C, Cardinali JL, Dorfman DM, Karlon W, Keeney M, Leith C, Long T, Murphy CE, Pillai V, Rosado FN, Seegmiller AC, Linden MA.: Participation in the College of American Pathologists Laboratory Accreditation Program Decreases Variability in B-Lymphoblastic Leukemia and Plasma Cell Myeloma Flow Cytometric Minimal Residual Disease Testing: A Follow-up Survey. Archives of Pathology and Laboratory Medicine August 2020 Notes: Online ahead of print.

Rentas S, Pillai V, Wertheim GB, Akgumus GT,Nichols KE, Deardorff MA, Conlin LK, Li MM, Olson TS, Luo M : Evolution of Histomorphologic, Cytogenetic, and Genetic Abnormalities in an Untreated Patient With MIRAGE Syndrome Cancer Genetics 245: 42-48, July 2020.

Liou A, Van Arnam J, Pillai V, Seif AE, Tasian SK, Phillips CA: Transient atypical monocytosis after α/β T-cell-depleted haploidentical hematopoietic stem cell transplantation. Pediatric Blood and Cancer 67(4), April 2020 Notes: Epub 2019 Dec 22.

Yang G, Faude S, Paessler ME, Wertheim GBW, Pillai V: CD19-Negative B-ALL Relapses after CAR T Cell Therapy are Associated with a Hypermutator Phenotype United States and Canadian Academy of Pathology 2020 Los Angeles, California March 2020.

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Last updated: 03/30/2021
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