Selected Publications

Wong KG, Cheng YF, Wu VH, Kiseleva AA, Li J, Poleshko A, Smith CL, Epstein JA.: Growth factor-induced activation of MSK2 leads to phosphorylation of H3K9me2S10 and corresponding changes in gene expression. Sci Adv 10: eadm9518, Mar 2024.

Padmanabhan A, de Soysa TY, Pelonero A, Sapp V, Shah PP, Wang Q, Li L, Lee CY, Sadagopan N, Nishino T, Ye L, Yang R, Karnay A, Poleshko A, Bolar N, Linares-Saldana R, Ranade SS, Alexanian M, Morton SU, Jain M, Haldar SM, Srivastava D, Jain R.: A genome-wide CRISPR screen identifies BRD4 as a regulator of cardiomyocyte differentiation. Nat Cardiovasc Res 2024.

Kiseleva AA, Poleshko A.: The secret life of chromatin tethers. FEBS Lett 2023.

Kiseleva AA, Cheng YC, Smith CL, Katz RA, Poleshko A.: PRR14 organizes H3K9me3-modified heterochromatin at the nuclear lamina. Nucleus 2023.

Kee J, Thudium S, Renner DM, Glastad K, Palozola K, Zhang Z, Li Y, Lan Y, Cesare J, Poleshko A, Kiseleva AA, Truitt R, Cardenas-Diaz FL, Zhang X, Xie X, Kotton DN, Alysandratos KD, Epstein JA, Shi PY, Yang W, Morrisey E, Garcia BA, Berger SL, Weiss SR, Korb E.: SARS-CoV-2 disrupts host epigenetic regulation via histone mimicry. Nature 2022.

Linares-Saldana R, Kim W, Bolar NA, Zhang H, Koch-Bojalad BA, Yoon S, Shah PP, Karnay A, Park DS, Luppino JM, Nguyen SC, Padmanabhan A, Smith CL, Poleshko A, Wang Q, Li L, Srivastava D, Vahedi G, Eom GH, Blobel GA, Joyce EF, Jain R.: BRD4 orchestrates genome folding to promote neural crest differentiation. Nat Genet 53(12), Dec 2021 Notes: doi: 10.1038/s41588-021-00980-2.

Smith CL, Lan Y, Jain R, Epstein JA, Poleshko A.: Global chromatin relabeling accompanies spatial inversion of chromatin in rod photoreceptors. Sci Adv 7: eabj3035, Sep 2021.

Smith CL, Poleshko A, Epstein JA.: The nuclear periphery is a scaffold for tissue-specific enhancers. Nucleic Acids Res 49: 6181-6195, Jun 2021.

Shah PP, Lv W, Rhoades JH, Poleshko A, Abbey D, Caporizzo MA, Linares-Saldana R, Heffler JG, Sayed N, Thomas D, Wang Q, Stanton LJ, Bedi K, Morley MP, Cappola TP, Owens AT, Margulies KB, Frank DB, Wu JC, Rader DJ, Yang W, Prosser BL, Musunuru K, Jain R.: Pathogenic LMNA variants disrupt cardiac lamina-chromatin interactions and de-repress alternative fate genes. Cell Stem Cell 28: 938-954, May 2021.

See K, Kiseleva AA, Smith CL, Liu F, Li J, Poleshko A, Epstein JA.: Histone methyltransferase activity programs nuclear peripheral genome positioning. Dev Biol 466: 90-98, Oct 2020.