Selected Publications

Linares-Saldana R, Kim W, Bolar NA, Zhang H, Koch-Bojalad BA, Yoon S, Shah PP, Karnay A, Park DS, Luppino JM, Nguyen SC, Padmanabhan A, Smith CL, Poleshko A, Wang Q, Li L, Srivastava D, Vahedi G, Eom GH, Blobel GA, Joyce EF, Jain R.: BRD4 orchestrates genome folding to promote neural crest differentiation. Nat Genet 53(12), Dec 2021 Notes: doi: 10.1038/s41588-021-00980-2.

Smith CL, Lan Y, Jain R, Epstein JA, Poleshko A.: Global chromatin relabeling accompanies spatial inversion of chromatin in rod photoreceptors. Sci Adv 7: eabj3035, Sep 2021.

Smith CL, Poleshko A, Epstein JA.: The nuclear periphery is a scaffold for tissue-specific enhancers. Nucleic Acids Res 49: 6181-6195, Jun 2021.

Shah PP, Lv W, Rhoades JH, Poleshko A, Abbey D, Caporizzo MA, Linares-Saldana R, Heffler JG, Sayed N, Thomas D, Wang Q, Stanton LJ, Bedi K, Morley MP, Cappola TP, Owens AT, Margulies KB, Frank DB, Wu JC, Rader DJ, Yang W, Prosser BL, Musunuru K, Jain R.: Pathogenic LMNA variants disrupt cardiac lamina-chromatin interactions and de-repress alternative fate genes. Cell Stem Cell 28: 938-954, May 2021.

See K, Kiseleva AA, Smith CL, Liu F, Li J, Poleshko A, Epstein JA.: Histone methyltransferase activity programs nuclear peripheral genome positioning. Dev Biol 466: 90-98, Oct 2020.

Dunlevy KL, Medvedeva V, Wilson JE, Hoque M, Pellegrin T, Maynard A, Kremp MM, Wasserman JS, Poleshko A, Katz RA.: The PRR14 heterochromatin tether encodes modular domains that mediate and regulate nuclear lamina targeting. J Cell Sci 133: jcs240416, May 2020.

Poleshko Andrey, Smith Cheryl L, Nguyen Son C, Sivaramakrishnan Priya, Wong Karen G, Murray John Isaac, Lakadamyali Melike, Joyce Eric F, Jain Rajan, Epstein Jonathan A: H3K9me2 orchestrates inheritance of spatial positioning of peripheral heterochromatin through mitosis. eLife 8: e49278, 10 2019.

Jain Rajan, Poleshko Andrey, Epstein Jonathan A: Beating the odds: programming proliferation in the mammalian heart. Genome medicine 10(1): 36, 05 2018.

Artap Stanley, Manderfield Lauren J, Smith Cheryl L, Poleshko Andrey, Aghajanian Haig, See Kelvin, Li Li, Jain Rajan, Epstein Jonathan A: Endocardial Hippo signaling regulates myocardial growth and cardiogenesis. Developmental biology 440(1): 22-30, 08 2018.

Poleshko Andrey, Shah Parisha P, Gupta Mudit, Babu Apoorva, Morley Michael P, Manderfield Lauren J, Ifkovits Jamie L, Calderon Damelys, Aghajanian Haig, Sierra-Pagán Javier E, Sun Zheng, Wang Qiaohong, Li Li, Dubois Nicole C, Morrisey Edward E, Lazar Mitchell A, Smith Cheryl L, Epstein Jonathan A, Jain Rajan: Genome-Nuclear Lamina Interactions Regulate Cardiac Stem Cell Lineage Restriction. Cell 171(3): 573-587.e14, Oct 2017.