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Stephen P. Hunger, MD
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Professor of Pediatrics (Oncology)
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Attending Physician, Children's Hospital of Philadelphia, Division of Oncology
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Chief, Division of Oncology, Children's Hospital of Philadelphia,
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Department of Pediatrics
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Director, Center for Childhood Cancer Research, Children's Hospital of Philadelphia
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Associate Director for Pediatric Research, Abramson Cancer Center
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Member, Executive Committee, Abramson Cancer Center
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Department: Pediatrics
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Contact information
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Division of Oncology
25 Colket Translational Research
11 Room 3060
39 3501 Civic Center Blvd
Philadelphia, PA 19104
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25 Colket Translational Research
11 Room 3060
39 3501 Civic Center Blvd
Philadelphia, PA 19104
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Office: 267-425-0197
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Email:
hungers@chop.edu
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hungers@chop.edu
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Education:
21 7 BS 1c (Applied Biology) c
3e Massachusetts Institute of Technology, 1981.
21 7 MD c
45 University of Connecticut School of Medicine, 1985.
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Permanent link21 7 BS 1c (Applied Biology) c
3e Massachusetts Institute of Technology, 1981.
21 7 MD c
45 University of Connecticut School of Medicine, 1985.
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187 Chen W, Chang T-C, Rabin KR, Raetz EA, Devidas M, Hunger SP, Ramirez NC, Mullighan CG, Loh ML, Wu G. : Performance of Two-phase Designs for the Time-to-event Outcome and a Case Study Assessing the Relapse Risk Associated with B-ALL Subtypes. JCO Clinical Cancer Informatics 9, May 2025 Notes: e2400223 [Epub 2025 May]
ef Psihogios AM, El-Khatib A, Matos K, Rabbi M, Rossoff J, Dinner S, Zeng K, Picos R, Ahmed A, Fleisher L, Hunger SP, Pai A, Laurenceau J-P, Rini C, Ph.D.1, Barakat L, Schwartz L, Murphy S, Yanez B. 112 : Human-Centered Design of a Personalized Digital Health Intervention to Promote Oral Chemotherapy Adherence in Adolescents and Young Adults with Hematologic Cancers. Pediatric Blood and Cancer May 9 2025 Notes: e31756 [Online ahead of print]
237 392. Xu J*, Sussman JH*, Yang A, Yoshimura S, Hu J, Chen C, Vincent T, Bandyopadhyay S, Wu D, Li EY, Chen GM, Diorio D, Newman H, Li A, Chen C-h, Bernt K, Wood BL, Winter S, Dunsmore KP, Devidas M, Pounds S, Hunger SP, Chiang MY, Di Giacomo D, Polonen P, Mullighan CG, Yang JJ, Tan K# , Teachey DT#. : STAT1-mediated Interferon-response Gene Signatures Associate with Preclinical JAK-inhibitor Sensitivity in T-cell Acute Lymphoblastic Leukemia. Blood Mar 18 2025 Notes: [Online ahead of print]
229 Chen* C, Xu* J, Vincent T, Tumulty JS, Yoshimura S, Alikarami F, Yu W, Ding Y-y, Chen C-h, Li EY, Bandyopadhyay S, Peng J, Pölönen P, Newman H, Wood BL, Hu J, Shraim R, Hughes A, Diorio C, Uppuluri L, Shi G, Ryan T, Fuller T, Loh ML, Raetz EA, Hunger SP, Pounds SB, Mullighan CG, Frank D, Yang JJ, Bernt K, Teachey# DT Tan# K. : Single-cell Pan-leukemia Signatures of HSPC-like Blasts Predict Drug Response and Clinical Outcome. Blood Mar 16 2025 Notes: [Online ahead of print]
1e3 Li D, Tasian SK, Wertheim G, Rheingold SR, Bernt KM, Newman H, Wainwright L, Wilmoth DM, Thiel B, Margolskee E, Pillai V, Luo M, Surrey LF, Paessler ME, Hunger SP, Li MM, Zhong Y. : Integrated Genomic Analysis to Reduce Chromosomal Analysis for the Diagnosis of Pediatric Hematological Malignancies: Addressing the Shortage of Cytogenetic Technologists. Haematologica Jan 30 2025 Notes: [Online ahead of print]
12e Raetz EA, Loh ML, Hunger SP. The ASPHO 2025 Distinguished Career Award goes to Dr. William L. Carroll. , in Press.: The ASPHO 2025 Distinguished Career Award goes to Dr. William L. Carroll. Pediatric Blood and Cancer 2025.
19f Hogan LE, Bhatla T, Xu X, Gore L, Raetz EA, Bhojwani D, Teachey DT, Hunger SP, Loh ML, Brown PA, Ji L: Severe Toxicity and Poor Efficacy of Reinduction Chemotherapy are Associated with Overall Poor Outcomes in Relapsed B-acute Lymphoblastic Leukemia: A Report from the Children’s Oncology Group AALL1331. Haematologica 2025 Notes: in Press.
2b1 Newman H, Lee SHR, Pölönen P, Shraim R, Li Y, Liu H, Aplenc R, Bandyopadhyay S, Chen C, Devidas M, Diorio C, Dunsmore K, Elghawy A, Elhachimi A, Fuller T, Gupta S, Hall J, Hughes A, Hunger SP, Loh ML, Martinez Z, McCoy M, Mullen C, Pounds S, Raetz E, Seffernick AE, Shi G, Sussman J, Tan K, Uppuluri L, Vincent T, Wang’ondu R, Winestone L, Winter SS, Wood B, Wu G, Xu J, Yang W, Mullighan** C, Yang** J, Bona** K, Teachey** DT. : Impact of Genetic Ancestry on Biology and Survival Outcomes in T-cell Acute Lymphoblastic Leukemia. Blood Cancer Discovery, in Press. Blood Cancer Discovery. In Press (eds.). 2025.
10a Oh BLZ, Hunger SP, Yeoh AEJ, Lee SHR. : Curing using the Minimal – Strategies For Treatment Reduction In Childhood Acute Lymphoblastic Leukemia. EJC Paediatric Oncology 2025 Notes: in Press.
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Selected Publications
271 Gupta* S, Rau* RE, Kairalla JA, Rabin KR, Wang C, Angiolillo AL, Alexander S, Carroll AJ, Conway S, Gore L, Kirsch I, Kubaney HR, Li A, McNeer JL, Militano O, Miller TP, Moyer Y, O’Brien MM, Okada M, Reshmi SC, Shago M, Wagner E, Winick N, Wood BL, Haworth-Wright T, Zaman F, Zugmaier G, Zupanec S, Devidas M, Hunger SP, Teachey DT, Raetz** EA, Loh** ML. *co-first authors; **co-senior authors.: Blinatumomab in standard risk pediatric B-acute lymphoblastic leukemia. New England Journal of Medicine 92: 875 - 891, Dec 2025 Notes: [Epub 2024 Dec 7]187 Chen W, Chang T-C, Rabin KR, Raetz EA, Devidas M, Hunger SP, Ramirez NC, Mullighan CG, Loh ML, Wu G. : Performance of Two-phase Designs for the Time-to-event Outcome and a Case Study Assessing the Relapse Risk Associated with B-ALL Subtypes. JCO Clinical Cancer Informatics 9, May 2025 Notes: e2400223 [Epub 2025 May]
ef Psihogios AM, El-Khatib A, Matos K, Rabbi M, Rossoff J, Dinner S, Zeng K, Picos R, Ahmed A, Fleisher L, Hunger SP, Pai A, Laurenceau J-P, Rini C, Ph.D.1, Barakat L, Schwartz L, Murphy S, Yanez B. 112 : Human-Centered Design of a Personalized Digital Health Intervention to Promote Oral Chemotherapy Adherence in Adolescents and Young Adults with Hematologic Cancers. Pediatric Blood and Cancer May 9 2025 Notes: e31756 [Online ahead of print]
237 392. Xu J*, Sussman JH*, Yang A, Yoshimura S, Hu J, Chen C, Vincent T, Bandyopadhyay S, Wu D, Li EY, Chen GM, Diorio D, Newman H, Li A, Chen C-h, Bernt K, Wood BL, Winter S, Dunsmore KP, Devidas M, Pounds S, Hunger SP, Chiang MY, Di Giacomo D, Polonen P, Mullighan CG, Yang JJ, Tan K# , Teachey DT#. : STAT1-mediated Interferon-response Gene Signatures Associate with Preclinical JAK-inhibitor Sensitivity in T-cell Acute Lymphoblastic Leukemia. Blood Mar 18 2025 Notes: [Online ahead of print]
229 Chen* C, Xu* J, Vincent T, Tumulty JS, Yoshimura S, Alikarami F, Yu W, Ding Y-y, Chen C-h, Li EY, Bandyopadhyay S, Peng J, Pölönen P, Newman H, Wood BL, Hu J, Shraim R, Hughes A, Diorio C, Uppuluri L, Shi G, Ryan T, Fuller T, Loh ML, Raetz EA, Hunger SP, Pounds SB, Mullighan CG, Frank D, Yang JJ, Bernt K, Teachey# DT Tan# K. : Single-cell Pan-leukemia Signatures of HSPC-like Blasts Predict Drug Response and Clinical Outcome. Blood Mar 16 2025 Notes: [Online ahead of print]
1e3 Li D, Tasian SK, Wertheim G, Rheingold SR, Bernt KM, Newman H, Wainwright L, Wilmoth DM, Thiel B, Margolskee E, Pillai V, Luo M, Surrey LF, Paessler ME, Hunger SP, Li MM, Zhong Y. : Integrated Genomic Analysis to Reduce Chromosomal Analysis for the Diagnosis of Pediatric Hematological Malignancies: Addressing the Shortage of Cytogenetic Technologists. Haematologica Jan 30 2025 Notes: [Online ahead of print]
12e Raetz EA, Loh ML, Hunger SP. The ASPHO 2025 Distinguished Career Award goes to Dr. William L. Carroll. , in Press.: The ASPHO 2025 Distinguished Career Award goes to Dr. William L. Carroll. Pediatric Blood and Cancer 2025.
19f Hogan LE, Bhatla T, Xu X, Gore L, Raetz EA, Bhojwani D, Teachey DT, Hunger SP, Loh ML, Brown PA, Ji L: Severe Toxicity and Poor Efficacy of Reinduction Chemotherapy are Associated with Overall Poor Outcomes in Relapsed B-acute Lymphoblastic Leukemia: A Report from the Children’s Oncology Group AALL1331. Haematologica 2025 Notes: in Press.
2b1 Newman H, Lee SHR, Pölönen P, Shraim R, Li Y, Liu H, Aplenc R, Bandyopadhyay S, Chen C, Devidas M, Diorio C, Dunsmore K, Elghawy A, Elhachimi A, Fuller T, Gupta S, Hall J, Hughes A, Hunger SP, Loh ML, Martinez Z, McCoy M, Mullen C, Pounds S, Raetz E, Seffernick AE, Shi G, Sussman J, Tan K, Uppuluri L, Vincent T, Wang’ondu R, Winestone L, Winter SS, Wood B, Wu G, Xu J, Yang W, Mullighan** C, Yang** J, Bona** K, Teachey** DT. : Impact of Genetic Ancestry on Biology and Survival Outcomes in T-cell Acute Lymphoblastic Leukemia. Blood Cancer Discovery, in Press. Blood Cancer Discovery. In Press (eds.). 2025.
10a Oh BLZ, Hunger SP, Yeoh AEJ, Lee SHR. : Curing using the Minimal – Strategies For Treatment Reduction In Childhood Acute Lymphoblastic Leukemia. EJC Paediatric Oncology 2025 Notes: in Press.
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