Stephen P. Hunger, MD

faculty photo
Professor of Pediatrics (Oncology)
Attending Physician, Children's Hospital of Philadelphia, Division of Oncology
Chief, Division of Oncology, Children's Hospital of Philadelphia, Department of Pediatrics
Director, Center for Childhood Cancer Research, Children's Hospital of Philadelphia
Associate Director for Pediatric Research, Abramson Cancer Center
Member, Executive Committee, Abramson Cancer Center
Department: Pediatrics

Contact information
Division of Oncology
Colket Translational Research
Room 3060
3501 Civic Center Blvd
Philadelphia, PA 19104
Office: 267-425-0197
Education:
BS (Applied Biology)
Massachusetts Institute of Technology, 1981.
MD
University of Connecticut School of Medicine, 1985.
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Selected Publications

Gupta* S, Rau* RE, Kairalla JA, Rabin KR, Wang C, Angiolillo AL, Alexander S, Carroll AJ, Conway S, Gore L, Kirsch I, Kubaney HR, Li A, McNeer JL, Militano O, Miller TP, Moyer Y, O’Brien MM, Okada M, Reshmi SC, Shago M, Wagner E, Winick N, Wood BL, Haworth-Wright T, Zaman F, Zugmaier G, Zupanec S, Devidas M, Hunger SP, Teachey DT, Raetz** EA, Loh** ML. *co-first authors; **co-senior authors.: Blinatumomab in standard risk pediatric B-acute lymphoblastic leukemia. New England Journal of Medicine 92: 875 - 891, Dec 2025 Notes: [Epub 2024 Dec 7]

Chen W, Chang T-C, Rabin KR, Raetz EA, Devidas M, Hunger SP, Ramirez NC, Mullighan CG, Loh ML, Wu G. : Performance of Two-phase Designs for the Time-to-event Outcome and a Case Study Assessing the Relapse Risk Associated with B-ALL Subtypes. JCO Clinical Cancer Informatics 9, May 2025 Notes: e2400223 [Epub 2025 May]

Psihogios AM, El-Khatib A, Matos K, Rabbi M, Rossoff J, Dinner S, Zeng K, Picos R, Ahmed A, Fleisher L, Hunger SP, Pai A, Laurenceau J-P, Rini C, Ph.D.1, Barakat L, Schwartz L, Murphy S, Yanez B. : Human-Centered Design of a Personalized Digital Health Intervention to Promote Oral Chemotherapy Adherence in Adolescents and Young Adults with Hematologic Cancers. Pediatric Blood and Cancer May 9 2025 Notes: e31756 [Online ahead of print]

392. Xu J*, Sussman JH*, Yang A, Yoshimura S, Hu J, Chen C, Vincent T, Bandyopadhyay S, Wu D, Li EY, Chen GM, Diorio D, Newman H, Li A, Chen C-h, Bernt K, Wood BL, Winter S, Dunsmore KP, Devidas M, Pounds S, Hunger SP, Chiang MY, Di Giacomo D, Polonen P, Mullighan CG, Yang JJ, Tan K# , Teachey DT#. : STAT1-mediated Interferon-response Gene Signatures Associate with Preclinical JAK-inhibitor Sensitivity in T-cell Acute Lymphoblastic Leukemia. Blood Mar 18 2025 Notes: [Online ahead of print]

Chen* C, Xu* J, Vincent T, Tumulty JS, Yoshimura S, Alikarami F, Yu W, Ding Y-y, Chen C-h, Li EY, Bandyopadhyay S, Peng J, Pölönen P, Newman H, Wood BL, Hu J, Shraim R, Hughes A, Diorio C, Uppuluri L, Shi G, Ryan T, Fuller T, Loh ML, Raetz EA, Hunger SP, Pounds SB, Mullighan CG, Frank D, Yang JJ, Bernt K, Teachey# DT Tan# K. : Single-cell Pan-leukemia Signatures of HSPC-like Blasts Predict Drug Response and Clinical Outcome. Blood Mar 16 2025 Notes: [Online ahead of print]

Li D, Tasian SK, Wertheim G, Rheingold SR, Bernt KM, Newman H, Wainwright L, Wilmoth DM, Thiel B, Margolskee E, Pillai V, Luo M, Surrey LF, Paessler ME, Hunger SP, Li MM, Zhong Y. : Integrated Genomic Analysis to Reduce Chromosomal Analysis for the Diagnosis of Pediatric Hematological Malignancies: Addressing the Shortage of Cytogenetic Technologists. Haematologica Jan 30 2025 Notes: [Online ahead of print]

Raetz EA, Loh ML, Hunger SP. The ASPHO 2025 Distinguished Career Award goes to Dr. William L. Carroll. , in Press.: The ASPHO 2025 Distinguished Career Award goes to Dr. William L. Carroll. Pediatric Blood and Cancer 2025.

Hogan LE, Bhatla T, Xu X, Gore L, Raetz EA, Bhojwani D, Teachey DT, Hunger SP, Loh ML, Brown PA, Ji L: Severe Toxicity and Poor Efficacy of Reinduction Chemotherapy are Associated with Overall Poor Outcomes in Relapsed B-acute Lymphoblastic Leukemia: A Report from the Children’s Oncology Group AALL1331. Haematologica 2025 Notes: in Press.

Newman H, Lee SHR, Pölönen P, Shraim R, Li Y, Liu H, Aplenc R, Bandyopadhyay S, Chen C, Devidas M, Diorio C, Dunsmore K, Elghawy A, Elhachimi A, Fuller T, Gupta S, Hall J, Hughes A, Hunger SP, Loh ML, Martinez Z, McCoy M, Mullen C, Pounds S, Raetz E, Seffernick AE, Shi G, Sussman J, Tan K, Uppuluri L, Vincent T, Wang’ondu R, Winestone L, Winter SS, Wood B, Wu G, Xu J, Yang W, Mullighan** C, Yang** J, Bona** K, Teachey** DT. : Impact of Genetic Ancestry on Biology and Survival Outcomes in T-cell Acute Lymphoblastic Leukemia. Blood Cancer Discovery, in Press. Blood Cancer Discovery. In Press (eds.). 2025.

Oh BLZ, Hunger SP, Yeoh AEJ, Lee SHR. : Curing using the Minimal – Strategies For Treatment Reduction In Childhood Acute Lymphoblastic Leukemia. EJC Paediatric Oncology 2025 Notes: in Press.

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Last updated: 07/10/2025
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