Karthik Rajasekaran, MD, FACS
Associate Professor of Otorhinolaryngology: Head and Neck Surgery at the Hospital of the University of Pennsylvania
Head/Neck Oncology Leadership Meeting Member, Cancer Service Line, Hospital of the University of Pennsylvania, Philadelphia, PA
Director of Facial Trauma, University of Pennsylvania
Director of Quality Improvement Education, University of Pennsylvania
Senior Fellow of the Leonard Davis Institute of Health Economics , University of Pennsylvania
Co-Director of Head and Neck Oncology and Microvascular Reconstruction Fellowship, University of Pennsylvania
Advisory Dean, Perelman School of Medicine
Department: Otorhinolaryngology: Head and Neck Surgery
Contact information
800 Walnut St, 18th Floor
Department of Otorhinolaryngology
Penn Medicine
Philadelphia, PA 19107
Department of Otorhinolaryngology
Penn Medicine
Philadelphia, PA 19107
Office: 2158295180
Publications
Education:
B.A. (Biology, Health and Society)
University of Rochester, 2005.
M.D. (Doctor of Medicine)
Chicago Medical School at Rosalind Franklin University of Medicine and Science, 2011.
Permanent linkB.A. (Biology, Health and Society)
University of Rochester, 2005.
M.D. (Doctor of Medicine)
Chicago Medical School at Rosalind Franklin University of Medicine and Science, 2011.
Selected Publications
Hughes T, Tenorio D, Rizvi S, Rajasekaran K, Meyer A, Moreira A: Impact of Race, Ethnicity, and Insurance Type on In-hospital Mortality in Children with Traumatic Injury. J Racial Ethn Health Disparities May 2026 Notes: doi: 10.1007/s40615-026-02991-3. Epub ahead of print.Lukens JN, Riina MD, Weinstein G, MacDuffie E, Ramkissoon A, Baron J, Berger M, Messing I, Gentile M, Maxwell R, Ojerholm E, Swisher-McClure S, Giron Santos A, Porier K, Basu D, Brody R, Cannady S, Carey R, Chalian A, Newman J, Rajasekaran K, Rassekh C, Shanti R, Cohen RB, Singh A, Sun L, Montone K, Lin A: Long-Term Results of a Phase II Clinical Trial of Radiation Volume and Dose De-intensification Following Transoral Robotic Surgery and Neck Dissection for Human Papillomavirus-Associated Oropharyngeal Squamous Cell Carcinoma. Int J Radiat Oncol Biol Phys Apr 2026 Notes: doi: 10.1016/j.ijrobp.2026.04.015. Epub ahead of print.
Lin SK, Deitermann AM, Hunter ER, Wang SY, Valdes Morales KL, Lubeck M, Miller CJ, Etzkorn JR, Sobanko JF, Higgins HW 2nd, Walker JL, Zhang J, Cannady SB, Rajasekaran K, Brody RM, Kovach SJ 3rd, Chang B, Lin IC, Fischer JP, Lukens JN, Cohen JV, Mitchell TC, Amaravadi RK, Mehta S, Briceño CA, McMurray SL: Mohs-Facilitated Excision: A Case Series of a Multidisciplinary Approach to Reduce Local Recurrence of Advanced Keratinocyte Carcinomas. J Am Acad Dermatol Apr 2026 Notes: doi: 10.1016/j.jaad.2026.04.011. Epub ahead of print.
Wang SY, Turner G, Valdes-Morales KL, Hunter ER, Kim M, Tran VA, Polen K, Haynes D, Miller CJ, Etzkorn JR, Sobanko JF, Walker JL, Zhang J, Brody RM, Cannady SB, Rajasekaran K, Farwell DG, Miura JT, Karakousis GC, Lukens JR, Amaravadi RK, Schuchter LM, Mitchell TC, Higgins HW 2nd, Carey RM: Accuracy of Sentinel Lymph Node Biopsy to Predict Nodal Metastasis in Head and Neck Merkel Cell Carcinoma. JAMA Otolaryngol Head Neck Surg 152(3): 313-322, Mar 2026.
Park SL, Painter MM, Manne S, Alcalde V, McLaughlin M, Sullivan MA, Mathew D, Torres L, Huang YJ, Reeg DB, Douek NR, Campos T, Klapholz M, Cardenas MA, Fang V, Ngiow SF, Kc W, Goel RR, Baxter AE, Wu JE, Tan M, Berry CT, Ellebrecht CT, Alexander HC, Papazian E, Liu Y, Rajasekaran K, Brody RM, Thaler ER, Basu D, Diab A, Giles JR, Wherry EJ: Tissue-resident exhausted and memory CD8+ T cells have distinct ontogeny, function and role in disease. Nat Immunol 27(1): 110-125, Jan 2026.
Deng J, Lukens JN, Murphy BA, McMenamin E, Rajasekaran K, Quinn RJ, Cohn JC, Schlessinger W, Andersen LP, Spinelli BA, Lin A: Photobiomodulation in Treatment of Head and Neck Cancer-Related Chronic Lymphedema: A Pilot Randomized Controlled Trial. Integr Cancer Ther Jan 2026 Notes: doi: 10.1177/15347354261439138
Moss W, Muralidhar A, Girela M, Rajasekaran K, Moreira A: Pediatric laryngeal trauma: An epidemiological study using the National Trauma Data Bank. Int J Pediatr Otorhinolaryngol Dec 2025 Notes: doi: 10.1016/j.ijporl.2025.112618.
Fu BJ, Potter AL, Pipkorn P, Kraimer KL, Chen MM, Rajasekaran K, Yang CJ, Lee JJ: Differences in Survival Following Surgery Versus Chemoradiotherapy for Clinical Stage T4a Laryngeal Squamous Cell Carcinoma: A Propensity Score-Matched Analysis. Head Neck Dec 2025 Notes: doi: 10.1002/hed.70114. Epub ahead of print.
Barrette LX, Gentile M, Rajasekaran K. Contralateral Tonsil in p16-Positive Tonsil Squamous Cell Carcinoma: Contralateral Tonsil in p16-Positive Tonsil Squamous Cell Carcinoma. JAMA Otolaryngol Head Neck Surg 151(12): 1115-1116, Dec 2025.
Halle TR, Cao AC, Naik AG, Weinstein GS, Lee JJ, Gobillot TA, Kaye ER, Brody RM, Basu D, O'Malley BW Jr, Farwell DG, Cannady SB, Lin A, Lukens J, Gentile M, Newman JG, Chalian AA, Rasskeh CH, Rajasekaran K: Risk of Occult Contralateral Neck Metastasis in Early-Stage HPV-Related Lateralized Cancer of the Base of the Tongue. Head Neck Dec 2025 Notes: doi: 10.1002/hed.70117. Epub ahead of print.
