Rebecca Lee Linn, M.D.

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Assistant Professor of Clinical Pathology and Laboratory Medicine
Department: Pathology and Laboratory Medicine

Contact information
Department of Pathology and Laboratory Medicine
The Children's Hospital of Philadelphia
3401 Civic Center Blvd.
Philadelphia, PA 19104
Office: 215-590-1728
Fax: 215-590-1736
Education:
BS (Biological Chemistry, Cum Laude)
Tulane University, New Orleans, Louisiana, 2007.
MD
St. Louis University School of Medicine, St. Louis, Missouri, 2012.
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Description of Clinical Expertise

Placental pathology
Perinatal pathology

Description of Research Expertise

Placental pathology
Perinatal pathology

Selected Publications

Rebecca Josowitz, Stacy Woyciechowski, Tanaya Jadhav, Tejas Jammihal, Rebecca L Linn, Jack Rychik, J William Gaynor, Ramakrishnan Rajagopalan, Nancy B Spinner : Placental Malperfusion Is Associated With Adverse Outcomes in Congenital Heart Disease and With Genetic Variants in Placental Developmental Pathways. JACC 86(19): 1704-1720, November 2025.

Rebecca Josowitz, Stacy Woyciechowski, Tanaya Jadhav, Tejas Jammihal, Rebecca L Linn, Jack Rychik, J William Gaynor, Ramakrishnan Rajagopalan, Nancy B Spinner : Placental Malperfusion Is Associated With Adverse Outcomes in Congenital Heart Disease and With Genetic Variants in Placental Developmental Pathways. JACC 86(19): 1704-1720, November 2025.

Hui Qiao, Carmelo Jacinto , Amanda Nguy, Lindsay Rogers, Rebecca L Linn : Upstairs-Downstairs Heart: A Rare Complex Cardiac Malformation with Superoinferior Ventricles. Society of Pediatric Pathology 2025 Fall Meeting, Philadelphia, PA October 2025.

Lucie Bennett-Stein, Rebecca L Linn: Postmortem Diagnosis of Non-Rhizomelic Chondrodysplasia Punctata in Diamniotic-Dichorionic Male Twins: A Rare Case Report. Society of Pediatric Pathology 2025 Fall Meeting, Philadelphia, PA October 2025.

Kavari SL, George AM, Linn RL, Kalish JM.: Characterization of placental pathology in Beckwith-Wiedemann Syndrome due to alterations in the KCNQ1OT1:TSS-DMR region. Placenta 171: 102-110, September 2025 Notes: no issue number.

Jacobwitz M, Xie M, Catalano J, Helbig I, Gaynor JW, Burnham N, Linn RL, Gebb J, Russell MW, Hakonarson H, Chaiyachati BH, Cristancho AG.: DNA methylation differences stratified by normalized fetal/placental weight ratios suggest neurodevelopmental deficits in neonates with congenital heart disease PLoS One 20(8): e0317944, August 2025.

Viaene AN, Steele J, Linn RL: Acquired neuropathology and its associations with key patterns of placental pathology. Acta Neropatholo Commun 13(1): 138, June 2025.

Golden TN, Mani S, Linn RL, Leite R, Trigg NA, Wilson A, Anton L, Mainigi M, Conine CC, Kaufman BA, Strauss JF, Parry S, Simmons RA: Extracellular Vesicles Alter Trophoblast Function in Pregnancies Complicated by COVID-19. Journal of Extracellular Vesicles 14(4): e70051, April 2025.

Linn RL, Forkpa M, Leite R, Guerrero JC, Reyes MC, Schwartz LE, Simmons RA, Parry S, Golden TN.: Severe Acute Respiratory Syndrome Coronavirus 2, the Human Placenta, and Adverse Perinatal Outcomes American Journal of Pathology 195(8): 1457-1466, April 2025.

Burrill N, Schindewolf E, Pilchman L, Wright R, Crane H, Gebb J, Khalek N, Soni S, Paidas Teefey C, Oliver ER, Linn R, Moldenhauer JS.: Whole Exome Sequencing in a Population of Fetuses With Structural Anomalies. Prenat Diagn 45(3): 310-317, March 2025.

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Last updated: 12/18/2025
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